(data stored in ACNUC7421 zone)

HOGENOM: STPNE1_1_PE1012

ID   STPNE1_1_PE1012                      STANDARD;      PRT;   213 AA.
AC   STPNE1_1_PE1012; Q97QV8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Redox-sensing transcriptional repressor rex;
DE   (STPNE1_1.PE1012).
GN   Name=rex; OrderedLocusNames=SP_1090;
OS   STREPTOCOCCUS PNEUMONIAE TIGR4.
OC   Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
OX   NCBI_TaxID=170187;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STPNE1_1.PE1012.
CC       Streptococcus pneumoniae TIGR4 chromosome, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:REX_STRPN
CC   -!- FUNCTION: Modulates transcription in response to changes in
CC       cellular NADH/NAD(+) redox state (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- INTERACTION:
CC       Q97SE5:gatC; NbExp=2; IntAct=EBI-2207177, EBI-2207053;
CC       Q97NV3:groS; NbExp=2; IntAct=EBI-2207177, EBI-2206949;
CC       P0A4S9:SP_1877; NbExp=2; IntAct=EBI-2207177, EBI-2207382;
CC       Q97SR4:uppS; NbExp=2; IntAct=EBI-2207177, EBI-2206983;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Probable).
CC   -!- SIMILARITY: Belongs to the transcriptional regulatory rex family.
CC   -!- GENE_FAMILY: HOG000250065 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q97QV8; -.
DR   EMBL; AE005672; AAK75202.1; -; Genomic_DNA.
DR   PIR; A95126; A95126.
DR   RefSeq; NP_345562.1; NC_003028.3.
DR   ProteinModelPortal; Q97QV8; -.
DR   IntAct; Q97QV8; 5.
DR   EnsemblBacteria; EBSTRT00000025544; EBSTRP00000024636; EBSTRG00000025544.
DR   GeneID; 931604; -.
DR   GenomeReviews; AE005672_GR; SP_1090.
DR   KEGG; spn:SP_1090; -.
DR   TIGR; SP_1090; -.
DR   GeneTree; EBGT00050000027130; -.
DR   OMA; LQILAFH; -.
DR   ProtClustDB; PRK05472; -.
DR   BioCyc; SPNE170187-1:SP_1090-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:InterPro.
DR   GO; GO:0051775; P:response to redox state; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
DR   HAMAP; MF_01131; Rex; 1; -.
DR   InterPro; IPR003781; CoA-bd.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR009718; Rex_DNA-bd_C.
DR   InterPro; IPR022876; Tscrpt_rep_Rex.
DR   InterPro; IPR011991; WHTH_trsnscrt_rep_DNA-bd.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Gene3D; G3DSA:1.10.10.10; Wing_hlx_DNA_bd; 1.
DR   Pfam; PF02629; CoA_binding; 1.
DR   Pfam; PF06971; Put_DNA-bind_N; 1.
DR   SMART; SM00881; CoA_binding; 1.
DR   HOGENOMDNA; STPNE1_1.PE1012; -.
KW   redox-sensing transcriptional repressor Rex;
KW   Complete proteome; Cytoplasm; DNA-binding; NAD; Repressor;
KW   Transcription; Transcription regulation.
SQ   SEQUENCE   213 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKDKQFAIPK ATAKRLSLYY RIFKRFHAEK IERANSKQIA EAIGIDSATV RRDFSYFGEL
     GRRGFGYDVK KLMTFFADLL NDNSITNVML VGIGNMGHAL LHYRFHERNK MKIIMAFDLD
     DHPEVGTQTP DGIPIYGISQ IKDKIKDADV KTAILTVPSV KSQEVANLLV DAGVKGILSF
     SPVHLHLPKD VVVQYVDLTS ELQTLLYFMR KED
//

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