(data stored in ACNUC7421 zone)

HOGENOM: STPYO2_1_PE1003

ID   STPYO2_1_PE1003                      STANDARD;      PRT;   500 AA.
AC   STPYO2_1_PE1003; Q7CN65;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Pyruvate kinase; EC=2.7.1 40; (STPYO2_1.PE1003).
GN   Name=pyk; OrderedLocusNames=spyM18_1230;
OS   STREPTOCOCCUS PYOGENES MGAS8232.
OC   Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
OX   NCBI_TaxID=186103;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STPYO2_1.PE1003.
CC       Streptococcus pyogenes MGAS8232, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:Q7CN65_STRP8
CC   -!- CATALYTIC ACTIVITY: ATP + pyruvate = ADP + phosphoenolpyruvate.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-
CC       glyceraldehyde 3-phosphate: step 5/5.
CC   -!- SIMILARITY: Belongs to the pyruvate kinase family.
CC   -!- GENE_FAMILY: HOG000021559 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q7CN65; -.
DR   EMBL; AE009949; AAL97840.1; -; Genomic_DNA.
DR   RefSeq; NP_607341.1; NC_003485.1.
DR   HSSP; P11974; 1AQF.
DR   ProteinModelPortal; Q7CN65; -.
DR   EnsemblBacteria; EBSTRT00000030046; EBSTRP00000028968; EBSTRG00000030046.
DR   GeneID; 993511; -.
DR   GenomeReviews; AE009949_GR; spyM18_1230.
DR   KEGG; spm:spyM18_1230; -.
DR   GeneTree; EBGT00050000027169; -.
DR   OMA; DEICSTA; -.
DR   ProtClustDB; PRK05826; -.
DR   BioCyc; SPYO186103:SPYM18_1230-MONOMER; -.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030955; F:potassium ion binding; IEA:InterPro.
DR   GO; GO:0004743; F:pyruvate kinase activity; IEA:EC.
DR   GO; GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR001697; Pyr_Knase.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase.
DR   InterPro; IPR011037; Pyrv_Knase-like_insert_dom.
DR   InterPro; IPR015794; Pyrv_Knase_a/b.
DR   InterPro; IPR015793; Pyrv_Knase_brl.
DR   InterPro; IPR015795; Pyrv_Knase_C-like.
DR   InterPro; IPR015806; Pyrv_Knase_insert_dom.
DR   Gene3D; G3DSA:2.40.33.10; PK_B_barrel_like; 1.
DR   Gene3D; G3DSA:3.20.20.60; Pyrv/PenolPyrv_Kinase_cat; 2.
DR   Gene3D; G3DSA:3.40.1380.20; Pyrv_Knase_a/b; 1.
DR   PANTHER; PTHR11817; Pyruvate_kinase; 1.
DR   Pfam; PF00224; PK; 1.
DR   Pfam; PF02887; PK_C; 1.
DR   PRINTS; PR01050; PYRUVTKNASE.
DR   SUPFAM; SSF50800; PK_B_barrel_like; 1.
DR   SUPFAM; SSF52935; Pyruvate_kinase; 1.
DR   SUPFAM; SSF51621; Pyrv/PenolPyrv_Kinase_cat; 1.
DR   TIGRFAMs; TIGR01064; Pyruv_kin; 1.
DR   HOGENOMDNA; STPYO2_1.PE1003; -.
KW   Complete proteome; Glycolysis; Kinase; Magnesium; Pyruvate;
KW   Transferase.
SQ   SEQUENCE   500 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNKRVKIVAT LGPAVEIRGG KKYGEDGYWA GQLDVEESAK KIAELIEAGA NVFRFNFSHG
     DHKEQGDRMA TVRLAEEIAR QKVGFLLDTK GPEMRTELFA DDAKEFSYVT GEKIRVATTQ
     GIQSTRDVIA LNVAGSLDIY DEVEVGHTIL IDDGKLGLKV IDKDIATRQF IVEVENDGII
     AKQKGVNIPN TKIPFPALAE RDNADIRFGL EQGLNFIAIS FVRTAKDVEE VREICRETGN
     DHVQLFAKIE NQQGIDNLDE IIEAADGIMI ARGDMGIEVP FEMVPVFQKM IITKVNAAGK
     AVITATNMLE TMTEKPRATR SEVSDVFNAV IDGTDATMLS GESANGKYPV ESVRTMATID
     RNAQTLLNEY GRLDSSAFPR TNKTDVIASA VKDATHSMDI KLVVTITETG NTARAISKFR
     PDADILAVTF DEKVQRALMI NWGVIPVLAE KPASTDDMFE VAERVAVEAG LVQSGDNIVI
     VAGVPVGTGG TNTMRVRTVK
//

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