(data stored in ACNUC7421 zone)

HOGENOM: STPYO2_1_PE1004

ID   STPYO2_1_PE1004                      STANDARD;      PRT;   337 AA.
AC   STPYO2_1_PE1004; Q8P0S6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=6-phosphofructokinase; Short=Phosphofructokinase; EC=2.7.1
DE   11;AltName: Full=Phosphohexokinase; (STPYO2_1.PE1004).
GN   Name=pfkA; Synonyms=pfk; OrderedLocusNames=spyM18_1231;
OS   STREPTOCOCCUS PYOGENES MGAS8232.
OC   Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
OX   NCBI_TaxID=186103;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STPYO2_1.PE1004.
CC       Streptococcus pyogenes MGAS8232, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:K6PF_STRP8
CC   -!- CATALYTIC ACTIVITY: ATP + D-fructose 6-phosphate = ADP + D-
CC       fructose 1,6-bisphosphate.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 3/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the phosphofructokinase family.
CC   -!- GENE_FAMILY: HOG000248870 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q8P0S6; -.
DR   EMBL; AE009949; AAL97841.1; -; Genomic_DNA.
DR   RefSeq; NP_607342.1; NC_003485.1.
DR   ProteinModelPortal; Q8P0S6; -.
DR   SMR; Q8P0S6; 1-298.
DR   EnsemblBacteria; EBSTRT00000029946; EBSTRP00000028868; EBSTRG00000029946.
DR   GeneID; 995115; -.
DR   GenomeReviews; AE009949_GR; spyM18_1231.
DR   KEGG; spm:spyM18_1231; -.
DR   GeneTree; EBGT00050000027028; -.
DR   OMA; MVHHDII; -.
DR   ProtClustDB; PRK03202; -.
DR   BioCyc; SPYO186103:SPYM18_1231-MON; -.
DR   GO; GO:0005945; C:6-phosphofructokinase complex; IEA:InterPro.
DR   GO; GO:0003872; F:6-phosphofructokinase activity; IEA:EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
DR   GO; GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
DR   HAMAP; MF_00339; Phosphofructokinase; 1; -.
DR   InterPro; IPR012003; ATP_PFK_prok.
DR   InterPro; IPR012828; PFKA_ATP.
DR   InterPro; IPR022953; Phosphofructokinase.
DR   InterPro; IPR015912; Phosphofructokinase_CS.
DR   InterPro; IPR000023; Phosphofructokinase_dom.
DR   Pfam; PF00365; PFK; 1.
DR   PIRSF; PIRSF000532; ATP_PFK_prok; 1.
DR   PRINTS; PR00476; PHFRCTKINASE.
DR   SUPFAM; SSF53784; Ppfruckinase; 1.
DR   TIGRFAMs; TIGR02482; PFKA_ATP; 1.
DR   PROSITE; PS00433; PHOSPHOFRUCTOKINASE; 1.
DR   HOGENOMDNA; STPYO2_1.PE1004; -.
KW   Allosteric enzyme; ATP-binding; Complete proteome; Cytoplasm;
KW   Glycolysis; Kinase; Magnesium; Metal-binding; Nucleotide-binding;
KW   Transferase.
SQ   SEQUENCE   337 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKRIAVLTSG GDAPGMNAAI RAVVRKAISE GMEVYGINRG YAGMVDGDIF PLGSKEVGDK
     ISRGGTFLYS ARYPEFAQLE GQLAGIEQLK KHGIEGVVVI GGDGSYHGAM RLTEHGFPAV
     GIPGTIDNDI AGTDYTIGFD TAVNTAVEAI DKLRDTSSSH GRTFVVEVMG RNAGDIALWA
     GIASGADQII VPEEEFDIEK VASTIQYDFE HKGKNHHIIV LAEGVMSGEA FAQKLKEAGD
     KSDLRVTNLG HILRGGSPTA RDRVIASWMG SHAVELLKEG KGGLAVGIHN EELVESPILG
     TAEEGALFSL TEEGKIIVNN PHKARLDFAA LNRSLSQ
//

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