(data stored in ACNUC7421 zone)

HOGENOM: STRE4_1_PE1013

ID   STRE4_1_PE1013                       STANDARD;      PRT;   214 AA.
AC   STRE4_1_PE1013; C0MA73;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Redox-sensing transcriptional repressor rex;
DE   (STRE4_1.PE1013).
GN   Name=rex; OrderedLocusNames=SEQ_1138;
OS   STREPTOCOCCUS EQUI SUBSP. EQUI 4047.
OC   Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
OX   NCBI_TaxID=553482;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STRE4_1.PE1013.
CC       Streptococcus equi subsp. equi 4047, complete genome.
CC       chromosome 1, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:REX_STRE4
CC   -!- FUNCTION: Modulates transcription in response to changes in
CC       cellular NADH/NAD(+) redox state (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the transcriptional regulatory rex family.
CC   -!- GENE_FAMILY: HOG000250065 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C0MA73; -.
DR   EMBL; FM204883; CAW93816.1; -; Genomic_DNA.
DR   RefSeq; YP_002746447.1; NC_012471.1.
DR   ProteinModelPortal; C0MA73; -.
DR   STRING; C0MA73; -.
DR   EnsemblBacteria; EBSTRT00000067302; EBSTRP00000063287; EBSTRG00000067579.
DR   GeneID; 7696084; -.
DR   GenomeReviews; FM204883_GR; SEQ_1138.
DR   KEGG; seu:SEQ_1138; -.
DR   GeneTree; EBGT00050000027130; -.
DR   OMA; LQILAFH; -.
DR   ProtClustDB; PRK05472; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:InterPro.
DR   GO; GO:0051775; P:response to redox state; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
DR   HAMAP; MF_01131; Rex; 1; -.
DR   InterPro; IPR003781; CoA-bd.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR009718; Rex_DNA-bd_C.
DR   InterPro; IPR022876; Tscrpt_rep_Rex.
DR   InterPro; IPR011991; WHTH_trsnscrt_rep_DNA-bd.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Gene3D; G3DSA:1.10.10.10; Wing_hlx_DNA_bd; 1.
DR   Pfam; PF02629; CoA_binding; 1.
DR   Pfam; PF06971; Put_DNA-bind_N; 1.
DR   SMART; SM00881; CoA_binding; 1.
DR   HOGENOMDNA; STRE4_1.PE1013; -.
KW   redox-sensing transcriptional repressor Rex;
KW   Complete proteome; Cytoplasm; DNA-binding; NAD; Repressor;
KW   Transcription; Transcription regulation.
SQ   SEQUENCE   214 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MVIDKSIPKA TAKRLSLYYR IFKRFYADQV EKASSKQIAD AMGIDSATVR RDFSYFGELG
     RRGFGYDVTK LMNFFADLLN DHSTTHVILV GCGNIGRALL HYRFHDRNKM QIVMGFDTDD
     NPMVGTKTPD DIPIYGISTI KEHLDNSGIE TAILTVPSIY AQEVADQLIE AGIRGILSFA
     PLHLQVPKGV IVQSVDLTSE LQTLLYFMNQ NHLD
//

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