(data stored in SCRATCH3701 zone)

HOGENOM6: STRE4_1_PE1039

ID   STRE4_1_PE1039                       STANDARD;      PRT;   831 AA.
AC   STRE4_1_PE1039; C0M7W7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (STRE4_1.PE1039).
GN   OrderedLocusNames=SEQ_1170;
OS   STREPTOCOCCUS EQUI SUBSP. EQUI 4047.
OC   Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
OX   NCBI_TaxID=553482;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STRE4_1.PE1039.
CC       Streptococcus equi subsp. equi 4047, complete genome.
CC       chromosome 1, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:C0M7W7_STRE4
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C0M7W7; -.
DR   EMBL; FM204883; CAW93866.1; -; Genomic_DNA.
DR   RefSeq; YP_002746473.1; NC_012471.1.
DR   STRING; C0M7W7; -.
DR   EnsemblBacteria; EBSTRT00000067368; EBSTRP00000062240; EBSTRG00000068262.
DR   GeneID; 7695423; -.
DR   GenomeReviews; FM204883_GR; SEQ_1170.
DR   KEGG; seu:SEQ_1170; -.
DR   GeneTree; EBGT00050000028052; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; STRE4_1.PE1039; -.
DR   PRODOM; STRE4_1_PE1039.
DR   SWISS-2DPAGE; STRE4_1_PE1039.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   831 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQDKHLVDVN LTSEMKTSFI DYAMSVIVAR ALPDVRDGLK PVHRRILYGM NELGVTPDKP
     HKKSARITGD VMGKYHPHGD SSIYEAMVRM AQWWSYRHML VDGHGNFGSM DGDGAAAQRY
     TEARMSKIAL ELLKDINKNT VDFQDNYDGN EREPLVLPAR FPNLLVNGAT GIAVGMATNI
     PPHNLAEAID AVKMVMENPD CTTRDLMEVL PGPDFPTGAL VMGRSGIHKA YETGKGSIVL
     RSRTEIETTS TGRERIVVTE FPYGINKTKV HEHIVRLAQE KRIEGITAVR DESSRQGVRF
     VIEVRRDASA NVILNNLFKL TSLQTNFSFN MLAIEGGIPK ILSLRQIIDN YILHQKDVIT
     RRTQFDKDKA EARAHILEGL LIALDHLDEV IAIIRNSETD IIAQAELMSR FDLSERQSQA
     ILDMRLRRLT GLERDKIQSE YDDLLALIAD LADILARPER IEAIIKEEME EIKRKYANPR
     RTELMIGEVL SLEDEDLIEE EDVLITLSNN GYIKRLAQDE FRSQKRGGRG VQGTGVNDDD
     FVRELVSTST HDTLLFFTNF GRVYRLKAYE IPEYGRAAKG LPVINLLKLD DGETIQTIIN
     AKKEDILDKY FFFTTKQGIV KRTEVSEFSN IRQNGLRALN LKEGDELINV LLTNGQEDII
     IGTRSGYSVR FNEATIRGMG RSATGVRGVK LREEDWVVGA SRINDKQEVL VITENGYGKR
     TSAAEYPTKG RGGKGIKTAN ITAKNGQLAG LMTVDGSEDI MVITTKGVII RTNVSSISQT
     GRSTLGVKVM RLDTDSKIVT FTLVQAEDND PTAIAQTDTA LTEAPINSSK E
//

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