(data stored in SCRATCH3701 zone)

HOGENOM6: STRG3_1_PE1106

ID   STRG3_1_PE1106                       STANDARD;      PRT;   818 AA.
AC   STRG3_1_PE1106; D3HDL0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase A subunit; (STRG3_1.PE1106).
GN   Name=gyrA; OrderedLocusNames=GALLO_1128;
OS   STREPTOCOCCUS GALLOLYTICUS UCN34.
OC   Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
OX   NCBI_TaxID=637909;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STRG3_1.PE1106.
CC       Streptococcus gallolyticus UCN34, complete genome.
CC       chromosome 1, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:D3HDL0_STRG3
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D3HDL0; -.
DR   EMBL; FN597254; CBI13620.1; -; Genomic_DNA.
DR   RefSeq; YP_003430551.1; NC_013798.1.
DR   EnsemblBacteria; EBSTRT00000092565; EBSTRP00000086417; EBSTRG00000092972.
DR   GeneID; 8777387; -.
DR   GenomeReviews; FN597254_GR; GALLO_1128.
DR   KEGG; sga:GALLO_1128; -.
DR   GeneTree; EBGT00050000028052; -.
DR   OMA; TGRGRIY; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; STRG3_1.PE1106; -.
DR   PRODOM; STRG3_1_PE1106.
DR   SWISS-2DPAGE; STRG3_1_PE1106.
KW   DNA gyrase A subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   818 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQDKNLIDVN LTSEMKTSFI DYAMSVIVAR ALPDVRDGLK PVHRRILYGM NELGVTPDKP
     HKKSARITGD VMGKYHPHGD SSIYEAMVRM AQWWSYRHML VDGHGNFGSM DGDGAAAQRY
     TEARMSKIAL EMLRDINKNT VDFQDNYDGS EREPLVLPSR FPNLLVNGAT GIAVGMATNI
     PPHNLGESID AVKLVMDNPD VTTRELMEVL PGPDFPTGAL VMGKSGIRKA YETGKGSIVL
     RSRTEIETTK SGRERIVVTE FPYGVNKTKV HEHIVRLAQE KRIEGITAVR DESSREGIRF
     IIEVRRDASA NVILNNLFKL TSLQTNFSFN MLAIENGVPK ILSLKQIIVD YIEHQKEVIV
     RRTEFDKAKA EKRAHILEGL LVALDHLDEV ISIIRNSETD VIAQGELMSR FDLSERQSQA
     ILDMRLRRLT GLEREKIQAE YDDLLALIAD LADILAKPER VVAIIKEEMD DIKRKYADPR
     RTELMVGEVL SLEDEDLIEE EDVLITLSNK GYIKRLAQDE FRAQKRGGRG VQGTGVNDDD
     FVRELVSTST HDHVYFMTNK GRVYRLKGYE IPEYGRTAKG LPIVNLLKLD EGEIVQTIIS
     QSGHDDNESY LFFVTRQGVV KRTKESEFSN IRQNGLKALN LKDGDELINV IRTNGNDDII
     IGTKTGYSVR FNESAVRSMS RSATGVRGVN LREGDEVVGA SRISDDQEVL VITEKGYGKR
     TLASEYPTKG RGGKGIKTAN ITEKNGQLAG LATVNGDEDI MVITDTGVII RTNVASISQT
     GRATLGVKIM RLDQDAKIMT FALVEPEEEE EKTGEDLE
//

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