(data stored in SCRATCH3701 zone)

HOGENOM6: STRM6_1_PE941

ID   STRM6_1_PE941                        STANDARD;      PRT;   822 AA.
AC   STRM6_1_PE941; D3H8Q9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, subunit A; EC=5.99.1 3; (STRM6_1.PE941).
GN   Name=gyrA; OrderedLocusNames=smi_1007;
OS   STREPTOCOCCUS MITIS B6.
OC   Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
OX   NCBI_TaxID=365659;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STRM6_1.PE941.
CC       Streptococcus mitis B6, complete genome.
CC       chromosome 1, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:D3H8Q9_STRM6
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D3H8Q9; -.
DR   EMBL; FN568063; CBJ22254.1; -; Genomic_DNA.
DR   RefSeq; YP_003446119.1; NC_013853.1.
DR   EnsemblBacteria; EBSTRT00000096329; EBSTRP00000090067; EBSTRG00000094892.
DR   GeneID; 8799026; -.
DR   GenomeReviews; FN568063_GR; smi_1007.
DR   KEGG; smb:smi_1007; -.
DR   GeneTree; EBGT00050000028052; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; STRM6_1.PE941; -.
DR   PRODOM; STRM6_1_PE941.
DR   SWISS-2DPAGE; STRM6_1_PE941.
KW   DNA gyrase, subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   822 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQDRNLVNVN LTKEMKTSFI DYAMSVIVAR ALPDVRDGLK PVHRRILYGM NELGVTPDKP
     HKKSARITGD VMGKYHPHGD SSIYEAMVRM AQWWSYRYML VDGHGNFGSM DGDGAAAQRY
     TEARMSKIAL EMLRDINKNT VDFVDNYDAN EREPLVLPAR FPNLLVNGAT GIAVGMATNI
     PPHNLGETID AVKLVMDNPE VTTKDLMEVL PGPDFPTGAL VMGKSGIHKA YETGKGSIVL
     RSRTEIEETK TGRERIVVTE FPYMVNKTKV HEHIVRLVQE KRIEGITAVR DESNREGVRF
     VIEVKRDASA NVILNNLFKM TQMQTNFGFN MLAIQNGVPK ILSLRQILDA YIEHQKEVVV
     RRTRFDKEKA EARAHILEGL LIALDHIDEV IRIIRASETD EEAQAELMSK FKLSERQSQA
     ILDMRLRRLT GLERDKIQSE YDDLLALIAD LADILAKPER VSQIIKDELD EVKRKFGDQR
     RTELMVGEVL SLEDEDLIEE SDVLITLSNK GYIKRLDQAE FTAQKRGGRG VQGTGVKDDD
     FVRELVSTST HDHLLFFTNK GRVYRLKGYE IPEYGRTAKG LPVVNLLKLD ESESIQTIIN
     VESERSDDAY LFFTTRHGIV KRTSVKEFAN IRQNGLKALN LKDEDELINV LLTEEDTDII
     IGTKFGYAVR FNQSTVRGMS RIATGVKGVN LRDGDTVVGA SVITDQDEVL IITEKGYGKR
     TVATEYPTKG RGGKGMKTAN VAEKNGPLSG LLTVKGDEDL MIITDTGVMI RTNVANISQT
     GRSTMGVKVM RLDQDAKIVT FTTVAAAEKE EVGTENETEG EA
//

If you have problems or comments...

PBIL Back to PBIL home page