(data stored in ACNUC7421 zone)

HOGENOM: STRP0_1_PE1001

ID   STRP0_1_PE1001                       STANDARD;      PRT;   267 AA.
AC   STRP0_1_PE1001; D6ZRJ0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Hydroxyethylthiazole kinase 1; EC=2.7.1 50;AltName:
DE   Full=4-methyl-5-beta-hydroxyethylthiazole kinase 1; (STRP0_1.PE1001).
GN   Name=thiM; Synonyms=thiM1; OrderedLocusNames=HMPREF0837_11001;
OS   STREPTOCOCCUS PNEUMONIAE TCH8431/19A.
OC   Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
OX   NCBI_TaxID=525381;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STRP0_1.PE1001.
CC       Streptococcus pneumoniae TCH8431/19A chromosome, complete genome.
CC       chromosome 1, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:D6ZRJ0_STRP0
CC   -!- CATALYTIC ACTIVITY: ATP + 4-methyl-5-(2-hydroxyethyl)thiazole =
CC       ADP + 4-methyl-5-(2-phosphonooxyethyl)thiazole.
CC   -!- COFACTOR: Magnesium (By similarity).
CC   -!- PATHWAY: Cofactor biosynthesis; thiamine diphosphate biosynthesis;
CC       4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-
CC       methylthiazole: step 1/1.
CC   -!- SIMILARITY: Belongs to the Thz kinase family.
CC   -!- GENE_FAMILY: HOG000114352 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D6ZRJ0; -.
DR   EMBL; CP001993; ADI69229.1; -; Genomic_DNA.
DR   RefSeq; YP_003724443.1; NC_014251.1.
DR   EnsemblBacteria; EBSTRT00000097885; EBSTRP00000092518; EBSTRG00000096986.
DR   GeneID; 9344257; -.
DR   GenomeReviews; CP001993_GR; HMPREF0837_11001.
DR   KEGG; snc:HMPREF0837_11001; -.
DR   GeneTree; EBGT00050000026805; -.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004417; F:hydroxyethylthiazole kinase activity; IEA:HAMAP.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00228; Thz_kinase; 1; -.
DR   InterPro; IPR000417; Hyethyz_kinase.
DR   PANTHER; PTHR20857:SF14; Hyethyz_kinase; 1.
DR   Pfam; PF02110; HK; 1.
DR   PIRSF; PIRSF000513; Thz_kinase; 1.
DR   PRINTS; PR01099; HYETHTZKNASE.
DR   TIGRFAMs; TIGR00694; ThiM; 1.
DR   HOGENOMDNA; STRP0_1.PE1001; -.
KW   ATP-binding; Complete proteome; Kinase; Magnesium; Metal-binding;
KW   Nucleotide-binding; Thiamine biosynthesis; Transferase.
SQ   SEQUENCE   267 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKRKDFNMTS LKLLKEKAPL VICITNDVVK NFTANGLVAL GASPAMSEFP ADLEDLLKYA
     GGLLINIGTL TDENWKLYQA ALKIAEKYNV PAVLDPVACG AGEYRKKVAD DLINNYKLAA
     IRGNAGEIAS LVGIDVASKG VDSAGVDNID EIALAANEKF NIPIVVTGEV DAIAVNGEVV
     TIHNGSAMMP KVIGTGCLLG AVVASFIGLE KGQELKSLET AMLVYNIAGE IAEKRPNGHL
     PGTFKAEFIN ALYEITDEDV KEFKRVK
//

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