(data stored in ACNUC7421 zone)

HOGENOM: STRPF_1_PE1007

ID   STRPF_1_PE1007                       STANDARD;      PRT;   193 AA.
AC   STRPF_1_PE1007; Q1J6M6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Xanthine phosphoribosyltransferase; Short=XPRTase; EC=2.4.2
DE   22; (STRPF_1.PE1007).
GN   Name=xpt; OrderedLocusNames=MGAS10750_Spy1007;
OS   STREPTOCOCCUS PYOGENES MGAS10750.
OC   Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
OX   NCBI_TaxID=370554;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STRPF_1.PE1007.
CC       Streptococcus pyogenes MGAS10750 chromosome, complete genome.
CC       chromosome 1, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:XPT_STRPF
CC   -!- FUNCTION: Converts the preformed base xanthine, a product of
CC       nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so
CC       it can be reused for RNA or DNA synthesis (By similarity).
CC   -!- CATALYTIC ACTIVITY: XMP + diphosphate = 5-phospho-alpha-D-ribose
CC       1-diphosphate + xanthine.
CC   -!- PATHWAY: Purine metabolism; XMP biosynthesis via salvage pathway;
CC       XMP from xanthine: step 1/1.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the purine/pyrimidine
CC       phosphoribosyltransferase family. XPT subfamily.
CC   -!- GENE_FAMILY: HOG000036777 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q1J6M6; -.
DR   EMBL; CP000262; ABF37957.1; -; Genomic_DNA.
DR   RefSeq; YP_602501.1; NC_008024.1.
DR   ProteinModelPortal; Q1J6M6; -.
DR   SMR; Q1J6M6; 1-190.
DR   STRING; Q1J6M6; -.
DR   EnsemblBacteria; EBSTRT00000041208; EBSTRP00000039603; EBSTRG00000041204.
DR   GeneID; 4067213; -.
DR   GenomeReviews; CP000262_GR; xpt.
DR   KEGG; spi:MGAS10750_Spy1007; -.
DR   eggNOG; COG0503; -.
DR   GeneTree; EBGT00050000026781; -.
DR   OMA; ATVYSFT; -.
DR   ProtClustDB; PRK09219; -.
DR   BioCyc; SPYO370554:MGAS10750_SPY1007-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000310; F:xanthine phosphoribosyltransferase activity; IEA:EC.
DR   GO; GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
DR   GO; GO:0046110; P:xanthine metabolic process; IEA:InterPro.
DR   HAMAP; MF_01184; XPRTase; 1; -.
DR   InterPro; IPR000836; PRibTrfase.
DR   InterPro; IPR010079; Xanthine_PRibTrfase.
DR   Pfam; PF00156; Pribosyltran; 1.
DR   TIGRFAMs; TIGR01744; XPRTase; 1.
DR   PROSITE; PS00103; PUR_PYR_PR_TRANSFER; FALSE_NEG.
DR   HOGENOMDNA; STRPF_1.PE1007; -.
KW   Complete proteome; Cytoplasm; Glycosyltransferase; Purine salvage;
KW   Transferase.
SQ   SEQUENCE   193 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQLLEERILT DGNILGENIL KVDNFLTHQV DYRLMKAIGK VFAQKYAEAG ITKVVTIEAS
     GIAPAVYAAE AMDVPMIFAK KHKNITMTEG ILTAEVYSFT KQVTSTVSIA GKFLSKEDKV
     LIIDDFLANG QAAKGLIEII GQAGAQVVGV GIVIEKSFQD GRRLIEDMGI EVTSLARIKN
     FENGNLNFLE ADA
//

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