(data stored in ACNUC7421 zone)

HOGENOM: STRPS_1_PE1

ID   STRPS_1_PE1                          STANDARD;      PRT;   453 AA.
AC   STRPS_1_PE1; B2IQY9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
DE   (STRPS_1.PE1).
GN   Name=dnaA; OrderedLocusNames=SPCG_0001;
OS   STREPTOCOCCUS PNEUMONIAE CGSP14.
OC   Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
OX   NCBI_TaxID=516950;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STRPS_1.PE1.
CC       Streptococcus pneumoniae CGSP14, complete genome.
CC       chromosome 1, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:DNAA_STRPS
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC   -!- GENE_FAMILY: HOG000235658 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B2IQY9; -.
DR   EMBL; CP001033; ACB89253.1; -; Genomic_DNA.
DR   RefSeq; YP_001834718.1; NC_010582.1.
DR   ProteinModelPortal; B2IQY9; -.
DR   STRING; B2IQY9; -.
DR   EnsemblBacteria; EBSTRT00000018196; EBSTRP00000017510; EBSTRG00000018196.
DR   GeneID; 6217988; -.
DR   GenomeReviews; CP001033_GR; SPCG_0001.
DR   KEGG; spw:SPCG_0001; -.
DR   GeneTree; EBGT00050000028345; -.
DR   OMA; CHTLNAL; -.
DR   ProtClustDB; PRK00149; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   HAMAP; MF_00377; DnaA_bact; 1; -.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR013317; DnaA_Hda.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   Gene3D; G3DSA:1.10.1750.10; DnaA_C; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; Trp_repress_rep; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
DR   HOGENOMDNA; STRPS_1.PE1; -.
KW   chromosomal replication initiation protein;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding.
SQ   SEQUENCE   453 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKEKQFWNRI LEFAQERLTR SMYDFYAIQA ELIKVEENVA TIFLPRSEME MVWEKQLKDI
     IVVAGFEIYD AEITPHYIFT KPQDTTSSQV EEATNLTLYD YSPKLVSIPY SDTGLKEKYT
     FDNFIQGDGN VWAVSAALAV SEDLALTYNP LFIYGGPGLG KTHLLNAIGN EILKNIPNAR
     VKYIPAESFI NDFLDHLRLG EMEKFKKTYR SLDLLLIDDI QSLSGKKVAT QEEFFNTFNA
     LHDKQKQIVL TSDRSPKHLE GLEERLVTRF SWGLTQTITP PDFETRIAIL QSKTEHLGYN
     FQSDTLEYLA GQFDSNVRDL EGAINDITLI ARVKKIKDIT IDIAAEAIRA RKQDVSQMLV
     IPIDKIQTEV GNFYGVSIKE MKGSRRLQNI VLARQVAMYL SRELTDNSLP KIGKEFGGKD
     HTTVIHAHAK IKSLIDQDDN LRLEIESIKK KIK
//

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