(data stored in SCRATCH3701 zone)

HOGENOM6: STRRD_1_PE8

ID   STRRD_1_PE8                          STANDARD;      PRT;   836 AA.
AC   STRRD_1_PE8; D2AVV1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA topoisomerase (STRRD_1.PE8) (ATP-hydrolyzing);
DE   EC=5.99.1 3; .
GN   OrderedLocusNames=Sros_0008;
OS   STREPTOSPORANGIUM ROSEUM DSM 43021.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptosporangineae; Streptosporangiaceae; Streptosporangium.
OX   NCBI_TaxID=479432;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STRRD_1.PE8.
CC       Streptosporangium roseum DSM 43021 chromosome, complete genome.
CC       1..88329 annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:D2AVV1_STRRD
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D2AVV1; -.
DR   EMBL; CP001814; ACZ83070.1; -; Genomic_DNA.
DR   RefSeq; YP_003335813.1; NC_013595.1.
DR   GeneID; 8663270; -.
DR   GenomeReviews; CP001814_GR; Sros_0008.
DR   KEGG; sro:Sros_0008; -.
DR   OMA; TGRGRIY; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; STRRD_1.PE8; -.
DR   PRODOM; STRRD_1_PE8.
DR   SWISS-2DPAGE; STRRD_1_PE8.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   836 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDVNTPLVE RIEPVDIQSE MQRSYMDYAM SVIVSRALPD VRDGLKPVHR RVLYAMYDGG
     YRPDRGYFKC SRVVGDVMGS YHPHGDSSIY GTVVRLAQPW ALRYTLIDGQ GNFGSPGNDM
     PAAMRYTECK LAPIAMEMIR DIDKDTVDFQ PNYDGRSQEP LVLPSRFPNL LVNGSAGIAV
     GMATNIPPHN LREVADGVRW ALQNPEASDE ELLEALIARV KGPDFPTGAL IVGRRGIDDA
     YRTGRGSITM RAIVEVEEDA KGRQCLVVTE LPYQVNPDNL ALSIAESVKE GRITGIADVR
     DESSSRVGQR LVIVLKRDAV AKVVLNNLYK HTQLQTTFGA NMLALVDGVP RTLRLDQFVR
     HYVAHQIEVV VRRTRYLLRK AEERAHILRA LLKALERMDE VIALIRRSPS ASAAQGGLMA
     LLEIDEIQAQ AILDMQLRKL AALERQQITD EYDTLMAHIT DYQAILASPE RQRTIVFDEL
     SEIVSKYGDE RKTEIIAYEG DMSIEDLLAE EDMVVTITRG GYAKRTNTDL YRAQKRGGKG
     VRGAQLRQDD IVDHFFVTTT HHWLLFFTNK GRVYRVKAYE LPDSGRDARG QHLANLLAMQ
     PDEVVMEVLD LRDYEVAPYL VLATRSGLVK KTRLSEYDSP RSGGLIAINL REDDEVIAAR
     LVSEEDDLLL VSRGAQSIRF TASDEALRPM GRATSGVIGM RFLGGDELLA MNRIGDGDDV
     LIATEGGYAK RTPADQYPVQ GRGGKGVLTA KIVSARGKLV GAAMVRPEDE VFAITSAGGV
     IRTSAGEIKQ SGRQTMGVRL MNLAEGDSVV ALARNAEALE TEHNDALETE QNGEGE
//

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