(data stored in ACNUC7421 zone)

HOGENOM: STRS4_1_PE14

ID   STRS4_1_PE14                         STANDARD;      PRT;   1088 AA.
AC   STRS4_1_PE14; C6GYT3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=ATP-dependent helicase/deoxyribonuclease subunit B;
DE   EC=3.1.-.-; EC=3.6.4 12;AltName: Full=ATP-dependent helicase/nuclease
DE   RexB; (STRS4_1.PE14).
GN   Name=rexB; OrderedLocusNames=SSUBM407_p016;
OS   STREPTOCOCCUS SUIS BM407.
OC   Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
OX   NCBI_TaxID=568814;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STRS4_1.PE14.
CC       Streptococcus suis BM407 plasmid pBM407, complete sequence.
CC       1..88329 annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:C6GYT3_STRS4
CC   -!- FUNCTION: The heterodimer acts as both an ATP-dependent DNA
CC       helicase and an ATP-dependent, dual-direction single-stranded
CC       exonuclease. Recognizes the chi site generating a DNA molecule
CC       suitable for the initiation of homologous recombination. This
CC       subunit has 5' -> 3' nuclease activity (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC   -!- COFACTOR: Magnesium (By similarity).
CC   -!- SUBUNIT: Heterodimer of AddA and RexB (By similarity).
CC   -!- SIMILARITY: Belongs to the helicase family. AddB/RexB type 2
CC       subfamily.
CC   -!- GENE_FAMILY: HOG000285113 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C6GYT3; -.
DR   EMBL; FM252033; CAZ55681.1; -; Genomic_DNA.
DR   RefSeq; YP_003024063.1; NC_012923.1.
DR   STRING; C6GYT3; -.
DR   EnsemblBacteria; EBSTRT00000087736; EBSTRP00000081187; EBSTRG00000087364.
DR   GeneID; 8149066; -.
DR   GenomeReviews; FM252033_GR; SSUBM407_p016.
DR   KEGG; ssb:SSUBM407_p016; -.
DR   GeneTree; EBGT00050000028409; -.
DR   OMA; VAKSIRQ; -.
DR   ProtClustDB; CLSK876674; -.
DR   GO; GO:0008409; F:5'-3' exonuclease activity; IEA:HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:HAMAP.
DR   GO; GO:0016817; F:hydrolase activity, acting on acid anhydrides; IEA:InterPro.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:HAMAP.
DR   HAMAP; MF_01453; AddB_type2; 1; -.
DR   InterPro; IPR014141; DNA_helicase_suRexB.
DR   InterPro; IPR011335; Restrct_endonuc_II-like.
DR   SUPFAM; SSF52980; Restrict_endonuc_II-like_core; 1.
DR   TIGRFAMs; TIGR02774; RexB_recomb; 1.
DR   HOGENOMDNA; STRS4_1.PE14; -.
KW   exonuclease RexB;
KW   ATP-binding; Complete proteome; DNA damage; DNA repair; Exonuclease;
KW   Hydrolase; Nuclease; Nucleotide-binding; Plasmid.
SQ   SEQUENCE   1088 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKLVYTDIRN PLTQYLTEQT ATFAEQGKRV FYIAPNSLSF EMERKVLEYL PEQATFDIIV
     TRFGQLARYL MIDRKEAGQP LDDVGLAMIF FRVLSQFEDG DLKVYGRLQT DFGFINQLVA
     LYKELQRANM SILDLEAMDS PDKQADLVKI FLAVTDILSK EGFEHQSKLA QLTGLVETGQ
     LDEQLKNIVL VVDGFSRFSA EEEALVSALN ERVSEILIGV YASKKAVQAT YAEGNVYQAN
     VDFLRQLSAQ FQTKATYIGQ EPVLDSIGKF SKNMEAYYDY SGTMIDLTPA DQEKIQLWEV
     VNQKEEVEQV ATAIRQHVHQ GARYKDILLL LGDVDSYKLQ IGKIFDKYDI PYYFGKAEEM
     SHHPLVHFVE SLERLRRYRF RAEDLLNLLK SGLYASISQK ELDLFESYIL FADMKGQAAF
     SRAFSVNGRA DYDAEVIKEK RLVYDLTVLE PLRAKIMEPL NQLFKAGPQS GTALLEKFMA
     FLEAIDLPKN MEKMSRNLSE VEQEKEEQVW KSFTHLLENF HQIFGKEKLK MDDFLAILQA
     GMQASHYRTV PATVDVVNVK SYDLIEPHTA KYVYAIGMGQ SNFPKVAKNT SLLTEEEMEK
     VNLVSASSSR FDLVSRENIK KNHAAMMSLL NSATEQLVIS TPQIYNEGED SLSPYIKILQ
     KMGLKSEERG RIKTLSPQDI GHYKSLLSRL IESERPSLET EEWEGQRAFW TVLVRHLKKK
     LESQSIEIPT ITGDIASKQL SDETLAALYP EDKPLNLSAS SLTNFYNNQY LYFVRNVLRL
     REQESIHPTA FQHGLFLHRI FERVVMDQSE LDFDQKVDKA ILCTRDEAEF AMFYNQDADA
     RYTEEVLDKI ARSSATILRD NDLVEIDGQE KSFRQDKALV FDLQNGKSVH VNGTIDRLDT
     LQINQAVGVV DYKSSDQSFS VGDFYNGLKP QLVTYLAALQ ELDETKDKPV FGAMYLHLQD
     PIIKLKDTKN LEQLEGAANT SLVYKGLFLK EESLGLNHFY QTRNQLYTED EFAVLLNHNQ
     ELYKQAAMDI LAGRFAINPY TKDGRSVAGE QLKAITGFEA DRHMGMARRL VKEAKRQDWM
     ERMKGGQD
//

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