(data stored in SCRATCH3701 zone)

HOGENOM6: STRSW_1_PE4367

ID   STRSW_1_PE4367                       STANDARD;      PRT;   864 AA.
AC   STRSW_1_PE4367; C9ZAK1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; (STRSW_1.PE4367).
GN   Name=gyrA; OrderedLocusNames=SCAB_45751;
OS   STREPTOMYCES SCABIEI 87.22.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptomycineae; Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=680198;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS STRSW_1.PE4367.
CC       Streptomyces scabiei 87.22, complete genome.
CC       1..88329 annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:C9ZAK1_STRSW
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C9ZAK1; -.
DR   EMBL; FN554889; CBG71635.1; -; Genomic_DNA.
DR   RefSeq; YP_003490180.1; NC_013929.1.
DR   GeneID; 8841415; -.
DR   GenomeReviews; FN554889_GR; SCAB_45751.
DR   KEGG; scb:SCAB_45751; -.
DR   OMA; TGRGRIY; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; STRSW_1.PE4367; -.
DR   PRODOM; STRSW_1_PE4367.
DR   SWISS-2DPAGE; STRSW_1_PE4367.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   864 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MADQNTPVTP EESGETVQRV EPVGLETEMQ RSYLDYAMSV IVSRALPDVR DGLKPVHRRV
     LYAMYDGGYR PEKGFYKCAR VVGDVMGNYH PHGDSSIYDA LVRLAQPWSM RMPLVDSNGN
     FGSPGNDPAA AMRYTECKMA PLSMEMVRDI DEDTVDFTDN YDGRSQEPTV LPARFPNLLI
     NGSAGIAVGM ATNIPPHNLR EVAAGAQWYL ENPEASHEDL LDALIERIKG PDFPTGALVV
     GRKGIEEAYR TGRGSITMRA VVEVEEIQNR QCLVVTELPY QTNPDNLAQK IADLVKDGKI
     GGIADVRDET SSRTGQRLVI VLKRDAVAKV VLNNLYKHTD LQTNFGANML ALVDGVPRTL
     SLDAFIRHWV THQIEVIVRR TKFRLRKAEE RAHILRGLLK ALDAIDEVIA LIRRSDTVDI
     ARTGLMDLLE IDEIQANAIL EMQLRRLAAL ERQKIIQEHD ELQAKIREYN EILASPVRQR
     GIVSAELAAI VEKFGDDRKT MLVPYDGDMS IEDLIAEEDI VVTVSRGGYV KRTKTVDYRA
     QKRGGKGVRG TKLKEDDIVD HFFVSTTHHW LLFFTNKGRV YRAKAYELPD AGRDARGQHV
     ANLLAFQPDE AIAEILAIRD YEATPYLVLA TKGGLVKKTP LKDYDSPRSG GVIAINLREK
     EDGSDDELIG AELVSPNDDI LLISKKAQSI RFTATDEALR PMGRATSGVK GMSFREGDEL
     LSMNVVRPGT FVFTATDGGY AKRTNVDEYR VQGRGGLGIK AAKIVEDRGS LVGALVVEET
     DEILAITLSG GVIRTRVNEI RETGRDTMGV QLINLGKRDA VVGIARNAEA GREAEEVDGD
     EAVDETAEGA ATTGTDEGEA PSSE
//

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