(data stored in ACNUC7421 zone)

HOGENOM: SULIN_1_PE1014

ID   SULIN_1_PE1014                       STANDARD;      PRT;   154 AA.
AC   SULIN_1_PE1014; C3NGF3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=6,7-dimethyl-8-ribityllumazine synthase; Short=DMRL
DE   synthase; Short=Lumazine synthase; EC=2.5.1 9;AltName: Full=Riboflavin
DE   synthase beta chain; (SULIN_1.PE1014).
GN   Name=ribH; OrderedLocusNames=YN1551_1107;
OS   SULFOLOBUS ISLANDICUS Y.N.15.51.
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=419942;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SULIN_1.PE1014.
CC       Sulfolobus islandicus Y.N.15.51 chromosome, complete genome.
CC       1..88329 annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:RISB_SULIN
CC   -!- FUNCTION: Riboflavin synthase is a bifunctional enzyme complex
CC       catalyzing the formation of riboflavin from 5-amino-6-(1'-D)-
CC       ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2-
CC       butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit
CC       catalyzes the condensation of 5-amino-6-(1'-D)-ribityl-amino-
CC       2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-
CC       phosphate yielding 6,7-dimethyl-8-lumazine (By similarity).
CC   -!- CATALYTIC ACTIVITY: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine =
CC       riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine.
CC   -!- PATHWAY: Cofactor biosynthesis; riboflavin biosynthesis;
CC       riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-
CC       ribitylamino)uracil: step 2/2.
CC   -!- SIMILARITY: Belongs to the DMRL synthase family.
CC   -!- GENE_FAMILY: HOG000229251 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C3NGF3; -.
DR   EMBL; CP001404; ACP48213.1; -; Genomic_DNA.
DR   RefSeq; YP_002840135.1; NC_012623.1.
DR   STRING; C3NGF3; -.
DR   GeneID; 7810838; -.
DR   GenomeReviews; CP001404_GR; YN1551_1107.
DR   KEGG; sin:YN1551_1107; -.
DR   OMA; IQGATKH; -.
DR   ProtClustDB; PRK00061; -.
DR   GO; GO:0009349; C:riboflavin synthase complex; IEA:InterPro.
DR   GO; GO:0004746; F:riboflavin synthase activity; IEA:EC.
DR   GO; GO:0009231; P:riboflavin biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00178; Lumazine_synth; 1; -.
DR   InterPro; IPR002180; DMRL_synthase.
DR   Gene3D; G3DSA:3.40.50.960; DMRL_synthase; 1.
DR   PANTHER; PTHR21058; DMRL_synthase; 1.
DR   Pfam; PF00885; DMRL_synthase; 1.
DR   SUPFAM; SSF52121; DMRL_synthase; 1.
DR   TIGRFAMs; TIGR00114; Lumazine-synth; 1.
DR   HOGENOMDNA; SULIN_1.PE1014; -.
KW   6,7-dimethyl-8-ribityllumazine synthase;
KW   Complete proteome; Riboflavin biosynthesis; Transferase.
SQ   SEQUENCE   154 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQEKSIRLGI VVAEFNYDIT QLMLQKALSH AKFLNAEVKV VIKVPGTFDM PLAIKKLLEK
     DFIDAVVTLG AVIKGETKHD EIVASQTARK IVDLSTEFNK PVTLGIIGHG ATHEQAVERI
     EEYATRAVEA AIKLVQRTRK IDELKEVKET VIID
//

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