(data stored in ACNUC7421 zone)

HOGENOM: SYNFM_1_PE10

ID   SYNFM_1_PE10                         STANDARD;      PRT;   250 AA.
AC   SYNFM_1_PE10; A0LE62;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=3-deoxy-manno-octulosonate cytidylyltransferase; EC=2.7.7
DE   38;AltName: Full=CMP-2-keto-3-deoxyoctulosonic acid synthase; Short=CKS;
DE   Short=CMP-KDO synthase; (SYNFM_1.PE10).
GN   Name=kdsB; OrderedLocusNames=Sfum_0010;
OS   SYNTROPHOBACTER FUMAROXIDANS MPOB.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Syntrophobacterales;
OC   Syntrophobacteraceae; Syntrophobacter.
OX   NCBI_TaxID=335543;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS SYNFM_1.PE10.
CC       Syntrophobacter fumaroxidans MPOB, complete genome.
CC       1..88329 annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:KDSB_SYNFM
CC   -!- FUNCTION: Activates KDO (a required 8-carbon sugar) for
CC       incorporation into bacterial lipopolysaccharide in Gram-negative
CC       bacteria (By similarity).
CC   -!- CATALYTIC ACTIVITY: CTP + 3-deoxy-D-manno-octulosonate =
CC       diphosphate + CMP-3-deoxy-D-manno-octulosonate.
CC   -!- PATHWAY: Nucleotide-sugar biosynthesis; CMP-3-deoxy-D-manno-
CC       octulosonate biosynthesis; CMP-3-deoxy-D-manno-octulosonate from
CC       3-deoxy-D-manno-octulosonate and CTP: step 1/1.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC       biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the kdsB family.
CC   -!- GENE_FAMILY: HOG000007602 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A0LE62; -.
DR   EMBL; CP000478; ABK15714.1; -; Genomic_DNA.
DR   RefSeq; YP_844149.1; NC_008554.1.
DR   ProteinModelPortal; A0LE62; -.
DR   STRING; A0LE62; -.
DR   GeneID; 4460159; -.
DR   GenomeReviews; CP000478_GR; Sfum_0010.
DR   KEGG; sfu:Sfum_0010; -.
DR   NMPDR; fig|335543.6.peg.10; -.
DR   eggNOG; COG1212; -.
DR   OMA; INVQADE; -.
DR   PhylomeDB; A0LE62; -.
DR   BioCyc; SFUM335543:SFUM_0010-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008690; F:3-deoxy-manno-octulosonate cytidylyltransferase activity; IEA:EC.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00057; CMP-KDO_synth; 1; -.
DR   InterPro; IPR003329; Cytidylyl_trans.
DR   InterPro; IPR004528; KdsB.
DR   Pfam; PF02348; CTP_transf_3; 1.
DR   TIGRFAMs; TIGR00466; KdsB; 1.
DR   HOGENOMDNA; SYNFM_1.PE10; -.
KW   Complete proteome; Cytoplasm; Lipopolysaccharide biosynthesis;
KW   Nucleotidyltransferase; Transferase.
SQ   SEQUENCE   250 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MRIVGIIPAR YQSSRFPGKP LVDILGKPMI RHVYERSARA GCLDRLIVAT DDARIAAAVA
     GFGGEALLTR ADHASGTDRL AEAARLLELD GADIVVNIQG DEPLVNHRMI EALVEALQCD
     RHCPMATLAF PSESLQDYNN PNVVKVVLDR GLRALYFSRA PIPFVRDGAA DAPAFLKHLG
     FYAYSASFLQ TFSRLPPGRL EGLEKLEQLR ALEHGYGIRV ALSPVDTRGV DTPEDLEAVV
     PVLAQDAVGA
//

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