(data stored in ACNUC7421 zone)

HOGENOM: THAPS_26_PE209

ID   THAPS_26_PE209                       STANDARD;      PRT;   373 AA.
AC   THAPS_26_PE209; B8C6V3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Methylthioribose-1-phosphate isomerase; Short=M1Pi;
DE   Short=MTR-1-P isomerase; EC=5.3.1 23;AltName:
DE   Full=S-methyl-5-thioribose-1-phosphate isomerase;AltName:
DE   Full=Translation initiation factor eIF-2B subunit alpha/beta/delta-like
DE   protein; (THAPS_26.PE209).
GN   ORFNames=THAPSDRAFT_35896;
OS   THALASSIOSIRA PSEUDONANA.
OC   Eukaryota; Stramenopiles; Bacillariophyta; Coscinodiscophyceae;
OC   Thalassiosirophycidae; Thalassiosirales; Thalassiosiraceae; Thalassiosira.
OX   NCBI_TaxID=35128;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS THAPS_26.PE209.
CC       Thalassiosira pseudonana chromosome 8 Thaps3 full sequence 1..1267198
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:MTNA_THAPS
CC   -!- FUNCTION: Catalyzes the interconversion of methylthioribose-1-
CC       phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-methyl-5-thio-alpha-D-ribose 1-phosphate =
CC       S-methyl-5-thio-D-ribulose 1-phosphate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via
CC       salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose
CC       1-phosphate: step 1/6.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits
CC       family. MtnA subfamily.
CC   -!- GENE_FAMILY: HOG000224730 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Thalassiosira_pseudonana;THAPS35896;THAPS35896;THAPS35896.
DR   EMBL; CM000644; - ;
DR   UniProtKB/Swiss-Prot; B8C6V3; -.
DR   EMBL; CM000644; EED90637.1; -; Genomic_DNA.
DR   RefSeq; XP_002291786.1; XM_002291750.1.
DR   ProteinModelPortal; B8C6V3; -.
DR   STRING; B8C6V3; -.
DR   EnsemblProtists; Thaps35896; Thaps35896; Thaps35896.
DR   GeneID; 7445592; -.
DR   KEGG; tps:THAPSDRAFT_35896; -.
DR   GeneTree; EPrGT00050000004326; -.
DR   ProtClustDB; CLSN2687998; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR005251; IF-2BI_MTNA.
DR   InterPro; IPR011559; Initiation_fac_2B_a/b/d.
DR   PANTHER; PTHR10233; IF-2B_related; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   TIGRFAMs; TIGR00524; EIF-2B_rel; 1.
DR   TIGRFAMs; TIGR00512; Salvage_mtnA; 1.
DR   HOGENOMDNA; THAPS_26.PE209; -.
KW   Thaps3589650019671820036002503210000011;
KW   B8C6V3; CM000644;
KW   Amino-acid biosynthesis; Cytoplasm; Isomerase;
KW   Methionine biosynthesis; Nucleus.
SQ   SEQUENCE   373 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDPANTLRS LIFDVDSATN KATLSVLDQL RLPDETMYTK IVNVQDAWDA IRSMRIRGAP
     LIAVVAVLGL AVDLSSNELT IGELDLISGI DEVKAFVTTK MEYLKTSRPT AVNLFNAMDE
     LKSFIDDDAI KTREEVVSAI VQHAYLMLER DVSDNKAIGS HGADDLLSRH VHPEGVCVVT
     ICNTGSLATA GWGTALGVAR ELQRRGKLRS IAALETRPYN QGSRLTAYEI MQEQMPNPIL
     LCDSMAASYL KSKGADVCVV GADRVCANGD TANKIGTFQL SIIAKEMGVE FFVASPFTTL
     DVELESGDMI EIEERPDGEM LESSGAPKGM KCWNPAFDVT PAKYISGIIT EKGVLKPSAD
     GTFDVKGFVS MHS
//

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