(data stored in SCRATCH3701 zone)

HOGENOM6: THASP_1_PE2872

ID   THASP_1_PE2872                       STANDARD;      PRT;   883 AA.
AC   THASP_1_PE2872; C4KB63;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (THASP_1.PE2872).
GN   OrderedLocusNames=Tmz1t_3041;
OS   THAUERA SP. MZ1T.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales;
OC   Rhodocyclaceae; Thauera.
OX   NCBI_TaxID=85643;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS THASP_1.PE2872.
CC       Thauera sp. MZ1T, complete genome.
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:C4KB63_THASP
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C4KB63; -.
DR   EMBL; CP001281; ACR01639.1; -; Genomic_DNA.
DR   RefSeq; YP_002890016.1; NC_011662.2.
DR   ProteinModelPortal; C4KB63; -.
DR   SMR; C4KB63; 30-521, 535-842.
DR   STRING; C4KB63; -.
DR   GeneID; 7874511; -.
DR   GenomeReviews; CP001281_GR; Tmz1t_3041.
DR   KEGG; tmz:Tmz1t_3041; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; THASP_1.PE2872; -.
DR   PRODOM; THASP_1_PE2872.
DR   SWISS-2DPAGE; THASP_1_PE2872.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   883 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTQFAKETLP ISLEEEMRHS YLDYAMSVIV GRALPDARDG LKPVHRRVLF AMHELSNDWN
     RAYKKSARIV GDVIGKYHPH GDTAVYDTIV RMAQDFSLRY MLVDGQGNFG SVDGDNAAAM
     RYTEIRMARI GHELLADIDK ETVDFGPNYD GSEKEPLVLP ARIPNLLING SAGIAVGMAT
     NIPPHNLGEI VDACLKLLAE PDTDIEALID IVQAPDFPTA GLIYGLAGVR EGYRTGRGRV
     IMRARTHFEP IGKTDRQAII VDELPYQVNK RTLQERMAEL VNEKKIEGIS EIRDESDKSG
     MRLVIELKRG EMPEVVLNKL FKHTQLQDSF GMNMVALVDG KPRLLNLKQM LVCFLEHRRE
     VVTRRTIFEL RKARDRGHIL EGLAVALSNV DEIIALIKAA PTPADAKREL MAREWRSALV
     EEMLSRALAD SYRPEGLDPQ YGLQAQGYRL SEAQAQAILE LRLQRLTGLE QDKIVGEYRE
     VMDVITDLLD ILARPERITA IIVEELGAIR NQFGDPRRSE LVMNTAEINI EDLITPEDMV
     VTLSHTGYFK RQPLADYRAQ RRGGRGKQAT SMKDEDFIDH LFVANTHDTV LCFSNRGRCY
     WLKVYEVPEG TRNSRGKPIV NLFPLVEGEK ITAVLPIKEF DEEHFVFMAT SEGTVKKTAL
     TAFSNPRKAG IIAVNLDDGD HLIGVAITDG QCDVMLFSDA GKAVRFAETD VRPMGRDARG
     VRGMTLEDGQ AVIAMLVAKD ESQSVLTATE NGYGKRTPVA EYTRHGRGTK GMIAIQTSDR
     NGRLVGAVLV EPSDEVMLIS TGGVLIRTSV ESIREMGRST QGVTLINLDE GTFLASIEKV
     AESESDESMR ASGEGAEGGE AEGGAQAAPG EGEAPAADEE GEA
//

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