(data stored in SCRATCH3701 zone)

HOGENOM6: THEBD_1_PE7

ID   THEBD_1_PE7                          STANDARD;      PRT;   834 AA.
AC   THEBD_1_PE7; D6Y209;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (THEBD_1.PE7).
GN   OrderedLocusNames=Tbis_0007;
OS   THERMOBISPORA BISPORA DSM 43833.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Pseudonocardineae; Pseudonocardiaceae; Thermobispora.
OX   NCBI_TaxID=469371;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS THEBD_1.PE7.
CC       Thermobispora bispora DSM 43833 chromosome, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:D6Y209_THEBD
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D6Y209; -.
DR   EMBL; CP001874; ADG86744.1; -; Genomic_DNA.
DR   RefSeq; YP_003650637.1; NC_014165.1.
DR   GeneID; 9166476; -.
DR   GenomeReviews; CP001874_GR; Tbis_0007.
DR   KEGG; tbi:Tbis_0007; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; THEBD_1.PE7; -.
DR   PRODOM; THEBD_1_PE7.
DR   SWISS-2DPAGE; THEBD_1_PE7.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   834 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTEVNTPPGP PADRIEVIDL QAEMQRSYMD YAMSVIVSRA LPDVRDGLKP VHRRVLYAMF
     EGGYRPDRGY FKSSRIVGDV MGSYHPHGDA SIYDTVVRLA QPWSLRYPLV DGQGNFGSPG
     NDPAAAMRYT ESRMAPIAME MLRDIDKDTV DFQPNYDGRS REPVVLPSRF PNLLVNGSSG
     IAVGMATNIP PHNLRETGEA VQWALEHPEL SDEELLEGLI ERIKGPDFPT GALIVGRRGI
     EEAYRTGRGS IIMRAVVELE EDAKGRQCLV VTELPYMVNP DNLALTIAEL VREGKISGIA
     DVRDESSSRT GQRLVIVLKR DAVPKVVLNN LYKHTQLQTT FGANMIALVD GVPRTLRLDQ
     FVRHYIRHQI DVVVRRTRFL LRKAEERAHI LRGLLKALER IDEVIELIRR SPSATEAQTG
     LMALLEIDEV QAQAILDMQL RKLAALERQQ IQDEYDGLMA QIADYNDILG SEMRQRRLVS
     EELGEIIAKY GDERRTKITA YEGDMSEEDL IAEEDVVVTI TRGGYAKRTS IDAYRAQRRG
     GKGVRGAQLR QDDIVEHFFV TSTHHWLLAF TNKGRVYRFK AYELPEAARD ARGQHLANLL
     AMQPDEHVME ILSLRNYDEA PYLVLATRSG MVKKTRLAEY DSPRSGGLIA INLRDDDEVI
     AARLVSEEDD LLLVSKNAQA IRFKATDEVL RPMGRATAGV IGMRFAEGDE LLAMEVIRDG
     DEEVLVATEG GYAKRTPADQ YPVQGRGGKG VLTAKIVQSR GKLIGAIMVR PEDEVFAITS
     NGGVIRTRAA EIKRSGRQTM GVRLMHLSEG DSLVALARNA ESLNNEENGA GDGV
//

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