(data stored in ACNUC7421 zone)

HOGENOM: THELT_1_PE1

ID   THELT_1_PE1                          STANDARD;      PRT;   444 AA.
AC   THELT_1_PE1; A8F346;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
DE   (THELT_1.PE1).
GN   Name=dnaA; OrderedLocusNames=Tlet_0001;
OS   THERMOTOGA LETTINGAE TMO.
OC   Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
OX   NCBI_TaxID=416591;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS THELT_1.PE1.
CC       Thermotoga lettingae TMO, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:DNAA_THELT
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC   -!- GENE_FAMILY: HOG000235658 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A8F346; -.
DR   EMBL; CP000812; ABV32574.1; -; Genomic_DNA.
DR   RefSeq; YP_001469638.1; NC_009828.1.
DR   ProteinModelPortal; A8F346; -.
DR   SMR; A8F346; 100-333.
DR   STRING; A8F346; -.
DR   GeneID; 5608554; -.
DR   GenomeReviews; CP000812_GR; Tlet_0001.
DR   KEGG; tle:Tlet_0001; -.
DR   OMA; QFIQNKE; -.
DR   ProtClustDB; PRK14088; -.
DR   BioCyc; TLET416591:TLET_0001-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   HAMAP; MF_00377; DnaA_bact; 1; -.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR013317; DnaA_Hda.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   Gene3D; G3DSA:1.10.1750.10; DnaA_C; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; Trp_repress_rep; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; FALSE_NEG.
DR   HOGENOMDNA; THELT_1.PE1; -.
KW   chromosomal replication initiation protein;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding.
SQ   SEQUENCE   444 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKSEIIESLK SKLNRRVWES WFGTFDVKEI GPDYVVFQVG NLFIREWLEK KYGSLISKTL
     RELFGKPMDF RIEHASAKTE EKLDSNEDEP LVKKRPLILT PLNPILTFEN FVVGPNNMFA
     YSTCLEVAKN PGKYNPLFLH GGVGLGKTHL LQAIGHYLFK HEPDMRVIYL TSERFLNELV
     DSIKKNRVQE FRDKFRNKID VLLLDDVQFL IGKTGIQTEL FHTFNELYNE GKQIVVCSDR
     DPQQLEKFQD RLVSRFQMGV VTKIEKPDEE TCFKIAQKMA QLENAELQED ILKLISKNFS
     DNLRRLRGAL VKLIMYQQIS GEKVDLQKAF ELLAIQNSYH NKSLPEEKLM NSICEIFGVS
     QEEILSKSRK KEVALARQIG MYVARNYMGF SLRKVADMFK RSHPTVSHTI QKLEELTNSG
     NMVIKSQIDR LARCVTGQIL DQSV
//

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