(data stored in ACNUC7421 zone)

HOGENOM: THET1_1_PE1004

ID   THET1_1_PE1004                       STANDARD;      PRT;   296 AA.
AC   THET1_1_PE1004; D1CG72;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Phosphoribosylaminoimidazole-succinocarboxamide synthase;
DE   EC=6.3.2 6;AltName: Full=SAICAR synthetase; (THET1_1.PE1004).
GN   Name=purC; OrderedLocusNames=Tter_1012;
OS   THERMOBACULUM TERRENUM ATCC BAA-798.
OC   Bacteria; Thermobaculum.
OX   NCBI_TaxID=525904;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS THET1_1.PE1004.
CC       Thermobaculum terrenum ATCC BAA-798 chromosome 1, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:D1CG72_THET1
CC   -!- CATALYTIC ACTIVITY: ATP + 5-amino-1-(5-phospho-D-
CC       ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate +
CC       (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-
CC       carboxamido)succinate.
CC   -!- PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway;
CC       5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-
CC       amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.
CC   -!- SIMILARITY: Belongs to the SAICAR synthetase family.
CC   -!- GENE_FAMILY: HOG000230360 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D1CG72; -.
DR   EMBL; CP001825; ACZ41928.1; -; Genomic_DNA.
DR   RefSeq; YP_003322750.1; NC_013525.1.
DR   ProteinModelPortal; D1CG72; -.
DR   GeneID; 8645499; -.
DR   GenomeReviews; CP001825_GR; Tter_1012.
DR   KEGG; ttr:Tter_1012; -.
DR   OMA; LTLMDEV; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004639; F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity; IEA:HAMAP.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00137; SAICAR_synth; 1; -.
DR   InterPro; IPR013816; ATP_grasp_subdomain_2.
DR   InterPro; IPR001636; SAICAR_synth.
DR   InterPro; IPR018236; SAICAR_synthetase_CS.
DR   Gene3D; G3DSA:3.30.470.20; ATP_grasp_subdomain_2; 1.
DR   PANTHER; PTHR11609; SAICAR_synt; 1.
DR   Pfam; PF01259; SAICAR_synt; 1.
DR   TIGRFAMs; TIGR00081; PurC; 1.
DR   PROSITE; PS01058; SAICAR_SYNTHETASE_2; 1.
DR   HOGENOMDNA; THET1_1.PE1004; -.
KW   ATP-binding; Complete proteome; Ligase; Nucleotide-binding;
KW   Purine biosynthesis.
SQ   SEQUENCE   296 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSKAVTETNL PGINLIHRGK VRDTYDLGDS LLMVATDRIS AFDWVLPTPI PDKGKVLSQI
     SVFWFEKLAD IVPNHFITDD INNYSHLLPY SDVLRGRSMI VKKANRIDYE CVVRGYITGS
     GWAEYKKQGT VAGKPMPEGL RDGDKLPEPI FTPARKNEEG HDENITYEIL ESEVGSDLAS
     QLRDISIQLY QDGRDYAETR GVIIADTKFE FGFVDGQLTL IDELLTPDSS RFWLESEYRP
     GESLPSLDKQ YVRDWLTQSG WDKNSQPPEL PDEVVEATRQ RYLEAYRMLT GKELEL
//

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