(data stored in ACNUC7421 zone)

HOGENOM: THET1_1_PE1006

ID   THET1_1_PE1006                       STANDARD;      PRT;   233 AA.
AC   THET1_1_PE1006; D1CG74;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Phosphoribosylformylglycinamidine synthase I; EC=6.3.5 3;
DE   (THET1_1.PE1006).
GN   OrderedLocusNames=Tter_1014;
OS   THERMOBACULUM TERRENUM ATCC BAA-798.
OC   Bacteria; Thermobaculum.
OX   NCBI_TaxID=525904;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS THET1_1.PE1006.
CC       Thermobaculum terrenum ATCC BAA-798 chromosome 1, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:D1CG74_THET1
CC   -!- CATALYTIC ACTIVITY: ATP + N(2)-formyl-N(1)-(5-phospho-D-
CC       ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2-
CC       (formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate.
CC   -!- PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway;
CC       5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-
CC       phospho-D-ribosyl)glycinamide: step 1/2.
CC   -!- SUBUNIT: Heterodimer of two subunits, purQ and purL (By
CC       similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Contains 1 glutamine amidotransferase type-1 domain.
CC   -!- GENE_FAMILY: HOG000238240 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D1CG74; -.
DR   EMBL; CP001825; ACZ41930.1; -; Genomic_DNA.
DR   RefSeq; YP_003322752.1; NC_013525.1.
DR   ProteinModelPortal; D1CG74; -.
DR   GeneID; 8645501; -.
DR   GenomeReviews; CP001825_GR; Tter_1014.
DR   KEGG; ttr:Tter_1014; -.
DR   OMA; HPENHVE; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004642; F:phosphoribosylformylglycinamidine synthase activity; IEA:HAMAP.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00421; PurQ; 1; -.
DR   InterPro; IPR017926; GATASE_1.
DR   InterPro; IPR011698; GATase_3.
DR   InterPro; IPR010075; PRibForGlyAmidine_synth_I.
DR   Pfam; PF07685; GATase_3; 1.
DR   PIRSF; PIRSF001586; FGAM_synth_I; 1.
DR   TIGRFAMs; TIGR01737; FGAM_synth_I; 1.
DR   PROSITE; PS51273; GATASE_TYPE_1; 1.
DR   HOGENOMDNA; THET1_1.PE1006; -.
KW   ATP-binding; Complete proteome; Cytoplasm; Glutamine amidotransferase;
KW   Ligase; Nucleotide-binding; Purine biosynthesis.
SQ   SEQUENCE   233 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MRIGIITFPG SNGDWDCYYA LREIPGFEPV MIWHKEHDLH GVSALILPGG FAHGDYLRAG
     AIARFSPIMH EVTRFASEGR PVIGICNGFQ ILTEAHLLPG ALIRNKNLLF RCSLVHVRVK
     SNRSPWLSSL REGEVLRLAI AHGQGNYFAD QDTLNYLLEN DMIALQYCGP NGEVTPEFNH
     NGSVMNIAGI TNEAGNVLGL MPHPERSADR LLGSADGRRI FMSLAVALKE VLV
//

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