(data stored in ACNUC30630 zone)

HOGENOM: THET8_1_PE1843

ID   THET8_1_PE1843                       STANDARD;      PRT;   204 AA.
AC   THET8_1_PE1843; P05379; Q5SH87;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Anthranilate synthase component II; EC=4.1.3 27;AltName:
DE   Full=Glutamine amido-transferase; (THET8_1.PE1843).
GN   Name=trpG; OrderedLocusNames=TTHA1843;
OS   THERMUS THERMOPHILUS HB8.
OC   Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
OX   NCBI_TaxID=300852;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS THET8_1.PE1843.
CC       Thermus thermophilus HB8, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:TRPG_THET8
CC   -!- CATALYTIC ACTIVITY: Chorismate + L-glutamine = anthranilate +
CC       pyruvate + L-glutamate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L-
CC       tryptophan from chorismate: step 1/5.
CC   -!- SUBUNIT: Tetramer of two components I and two components II.
CC   -!- MISCELLANEOUS: Component I catalyzes the formation of anthranilate
CC       using ammonia rather than glutamine, whereas component II provides
CC       glutamine amidotransferase activity.
CC   -!- SIMILARITY: Contains 1 glutamine amidotransferase type-1 domain.
CC   -!- GENE_FAMILY: HOG000025029 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; P05379; Q5SH87; -.
DR   EMBL; X07744; CAA30567.1; -; Genomic_DNA.
DR   EMBL; AP008226; BAD71666.1; -; Genomic_DNA.
DR   RefSeq; YP_145109.1; NC_006461.1.
DR   ProteinModelPortal; P05379; -.
DR   STRING; P05379; -.
DR   GeneID; 3169403; -.
DR   GenomeReviews; AP008226_GR; TTHA1843.
DR   KEGG; ttj:TTHA1843; -.
DR   NMPDR; fig|300852.3.peg.1319; -.
DR   eggNOG; COG0512; -.
DR   OMA; SVDEIMG; -.
DR   ProtClustDB; PRK05670; -.
DR   BioCyc; TTHE300852:TTHA1843-MON; -.
DR   GO; GO:0004049; F:anthranilate synthase activity; IEA:EC.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR006220; Anth_synthII.
DR   InterPro; IPR001317; CarbamoylP_synth_GATase_dom.
DR   InterPro; IPR011702; GATASE.
DR   InterPro; IPR017926; GATASE_1.
DR   InterPro; IPR006221; TrpG_papA.
DR   Pfam; PF00117; GATase; 1.
DR   PRINTS; PR00097; ANTSNTHASEII.
DR   PRINTS; PR00099; CPSGATASE.
DR   PRINTS; PR00096; GATASE.
DR   TIGRFAMs; TIGR00566; TrpG_papA; 1.
DR   PROSITE; PS51273; GATASE_TYPE_1; 1.
DR   HOGENOMDNA; THET8_1.PE1843; -.
KW   anthranilate synthase component II;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis;
KW   Complete proteome; Glutamine amidotransferase; Lyase;
KW   Reference proteome; Tryptophan biosynthesis.
SQ   SEQUENCE   204 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAANGAKGRK VMRVLVVDNY DSFTYNLVQY LGELGAEPIV WRNDRFRLEE VEALDPDRIL
     ISPGPCTPFE AGLSVPLVQR YAPRYPILGV CLGHQAIGAA FGGKVVPAPV LMHGKVSPIH
     HDGTGVFRGL DSPFPATRYH SLAVVEVPEA LVVNAWAEEA GGRTVMGFRH RDYPTHGVQF
     HPESYLTEAG KLILKNFLED PWTR
//

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