(data stored in ACNUC7421 zone)

HOGENOM: THICR_1_PE1000

ID   THICR_1_PE1000                       STANDARD;      PRT;   165 AA.
AC   THICR_1_PE1000; Q31GX8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=RNA pyrophosphohydrolase; EC=3.6.1 -;AltName:
DE   Full=(Di)nucleoside polyphosphate hydrolase; (THICR_1.PE1000).
GN   Name=rppH; Synonyms=nudH; OrderedLocusNames=Tcr_1000;
OS   THIOMICROSPIRA CRUNOGENA XCL-2.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales;
OC   Piscirickettsiaceae; Thiomicrospira.
OX   NCBI_TaxID=317025;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS THICR_1.PE1000.
CC       Thiomicrospira crunogena XCL-2, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:RPPH_THICR
CC   -!- FUNCTION: Accelerates the degradation of transcripts by removing
CC       pyrophosphate from the 5'-end of triphosphorylated RNA, leading to
CC       a more labile monophosphorylated state that can stimulate
CC       subsequent ribonuclease cleavage (By similarity).
CC   -!- COFACTOR: Divalent ions (By similarity).
CC   -!- SIMILARITY: Belongs to the Nudix hydrolase family. RppH subfamily.
CC   -!- SIMILARITY: Contains 1 nudix hydrolase domain.
CC   -!- GENE_FAMILY: HOG000066723 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q31GX8; -.
DR   EMBL; CP000109; ABB41595.1; -; Genomic_DNA.
DR   RefSeq; YP_391269.1; NC_007520.2.
DR   ProteinModelPortal; Q31GX8; -.
DR   STRING; Q31GX8; -.
DR   GeneID; 3760486; -.
DR   GenomeReviews; CP000109_GR; Tcr_1000.
DR   KEGG; tcx:Tcr_1000; -.
DR   NMPDR; fig|317025.3.peg.786; -.
DR   eggNOG; COG0494; -.
DR   OMA; GQKQIWY; -.
DR   PhylomeDB; Q31GX8; -.
DR   BioCyc; TCRU317025:TCR_1000-MON; -.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   HAMAP; MF_00298; Nudix_RppH; 1; -.
DR   InterPro; IPR020476; Nudix_hydrolase.
DR   InterPro; IPR020084; NUDIX_hydrolase_CS.
DR   InterPro; IPR000086; NUDIX_hydrolase_dom.
DR   InterPro; IPR015797; NUDIX_hydrolase_dom-like.
DR   InterPro; IPR022927; RppH.
DR   Gene3D; G3DSA:3.90.79.10; NUDIX_hydrolase; 1.
DR   Pfam; PF00293; NUDIX; 1.
DR   PRINTS; PR00502; NUDIXFAMILY.
DR   SUPFAM; SSF55811; NUDIX_hydrolase; 1.
DR   PROSITE; PS51462; NUDIX; 1.
DR   PROSITE; PS00893; NUDIX_BOX; 1.
DR   HOGENOMDNA; THICR_1.PE1000; -.
KW   NUDIX hydrolase;
KW   Complete proteome; Hydrolase.
SQ   SEQUENCE   165 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MIDADGYRPN VGIIIVNKEG KLFWGKRLYQ DAWQFPQGGV RENETPQQAV FRELKEEVGL
     EPSDVRVLGR TKDWLTYDLP KHLIRHYSQP VCIGQKQIWF LLGMLSDDEK INLNTHETPE
     FEGWSWVDYW VPVQNVVEFK QSVYHQALTE LETHLHKFWT KEHVG
//

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