(data stored in ACNUC11299 zone)

HOGENOM: TRBRU1_3_PE489

ID   TRBRU1_3_PE489                       STANDARD;      PRT;   1765 AA.
AC   TRBRU1_3_PE489; D6XEQ9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA-directed RNA polymerase; EC=2.7.7 6; (TRBRU1_3.PE489).
GN   ORFNames=Tb927.4.5020;
OS   TRYPANOSOMA BRUCEI TREU927.
OC   Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Trypanosoma.
OX   NCBI_TaxID=185431;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS TRBRU1_3.PE489.
CC       Trypanosoma brucei TREU927 chromosome 4, complete sequence.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:D6XEQ9_TRYB2
CC   -!- CATALYTIC ACTIVITY: Nucleoside triphosphate + RNA(n) = diphosphate
CC       + RNA(n+1).
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC   -!- GENE_FAMILY: HOG000222975 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D6XEQ9; -.
DR   EMBL; CP000067; AAZ11092.1; -; Genomic_DNA.
DR   RefSeq; XP_844651.1; XM_839558.1.
DR   ProteinModelPortal; D6XEQ9; -.
DR   GeneID; 3657041; -.
DR   EuPathDB; EupathDB:Tb927.4.5020; -.
DR   ProtClustDB; CLSZ2441388; -.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:EC.
DR   InterPro; IPR000722; RNA_pol_asu.
DR   InterPro; IPR006592; RNA_pol_N.
DR   InterPro; IPR007080; RNA_pol_Rpb1_1.
DR   InterPro; IPR007066; RNA_pol_Rpb1_3.
DR   InterPro; IPR007083; RNA_pol_Rpb1_4.
DR   InterPro; IPR007081; RNA_pol_Rpb1_5.
DR   InterPro; IPR007075; RNA_pol_Rpb1_6.
DR   InterPro; IPR007073; RNA_pol_Rpb1_7.
DR   Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR   Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR   Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR   Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR   Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR   Pfam; PF04992; RNA_pol_Rpb1_6; 1.
DR   Pfam; PF04990; RNA_pol_Rpb1_7; 1.
DR   SMART; SM00663; RPOLA_N; 1.
DR   HOGENOMDNA; TRBRU1_3.PE489; -.
KW   RNA polymerase IIA largest subunit;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW   Transferase.
SQ   SEQUENCE   1765 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSGGAALPVS QMELQKVNEV QFEIFKERQI KSYAVCLVEH AKSYERGRPV RGGINDLRMG
     TTDFEFACET CHRKHPECPG HFGYIELAEP VFNIGVFDLV LQVLKCVCKT CGALLLNTRE
     QDVHKKLQHM TGLNRLRQVA KMAEAKCRVS TSTEDDMGID GFDSAPFNGG SGMGPGATRG
     CGASQPRVSR FYGIYPTLVI KAVHEEQDAE WHADKVRQVL DRVSDDDARL MGFDPQRCHP
     RDLVLTVLPV PPPQVRPAIS FGGLRSDDEL THQIMSIVKR NNQLRRDKES DVQAAIDRSR
     ALLQEHVATY FNNASTYYKP TKVNDTKKLK SLTERLKGKY GRLRGNLMGK RVDFSARTVI
     TGDPNIDVDE VGVPFSVAMT LTFPERVNTV NKKRLTEFAR RTVYPSANYI HHPNGTITKL
     ALLRDRSKVT LNIGDVVERH VINGDVVLFN RQPTLHRMSM MGHRVRVLNY NTFRLNLSCT
     TPYNADFDGD EMNLHVPQSL LTKAELIEMM MVPKNFVSPN KSAPCMGIVQ DSLLGSYRLT
     DKDTFLDKYF VQSVALWLDL WQLPIPAILK PRPLWTGKQV FSLILPEVNH PATPQDRPPF
     PHNDSVVMIR RGQLLCGPIT KSIVGAAPGS LIHVIFNEHG SDEVARFING VQRVTTFFLL
     NFGFSVGVQD TVADSDTLRQ MNDVLVKTRR NVEKIGAAAN NRTLNRKAGM TLLQSFEADV
     NSALNKCREE AAKKALSNVR RTNSFKVMIE AGSKGTDLNI CQIAVFVGQQ NVAGSRIPFG
     FRRRTLPHFM LDDYGETSRG MANRGYVEGL KPHEFFFHTM AGREGLIDTA VKTSDTGYLQ
     RKLIKALEDV HAAYDGTVRN ANDELIQFMY GEDGLDGARI EGGQLFPLPF RDDKEMEDTY
     KYEYDVDGTF SGKVGGNYMD PHVRKMLRAD PQNVRKLQEE YEQLTADREW SRKMLDLEDR
     DKLKLNLPVN PGRLIQNARS TMGKRSQVSN LSPITIIDHV RKLQEDLMKL FPSYHRGGDG
     YIRNTLSRER IESALTLFNV HLRQLLASKR VLKEYKLNDR AFEYLLKEIR TKYHQSLTTP
     GENIGAIAAQ SCGEPATQMT LNTFHNAGIS SKNVTLGVPR LLELLNVSRN QKHASMTVSL
     FPPYDEKRNA QKAQHLIEYC TLESITRRIQ FIYDPDPRHT VVEADRDILE LEWNVMDESD
     AELRIQEVVA GSPWVVRLEL DVDMVTDKAL DMKDVKQAIL RVDESYIIET GMANNVRQRT
     IRMRSRYNEG ADSIPKLKRE IPALLARVHL RGIPGVRRAL LKDTTEFTVD QATGKMSGNK
     IWAIDTDGTA LRRAFIGVVG EDGKNIINAV KTSSNKVPEV CSLLGIEAAR SKMLTELREA
     YLAYGLNINY RHYTILVDTI CQHGYLMAVS RSGINRSDTS GPLMRCSFEE TVKVLMAAAS
     FGECDPVRGV SANLVLGNQA RVGTGLFDLV LNMAALQQAV PQAEAVAPGK DVNVYHSLGS
     TLQQNIQSSI AYRPRDHDAT PFVNNASLFL RQGFGGGSSS APVTASAPYN PSTTYHGGRL
     EASAVHRSQA YSTSPALEYG GREASASQMY SVMSSASAFN PVSTRMSSVA HSYSEYSEAS
     SYHLQHSVAP TSMQASLPRT DNSMTMQGIG SVSVPYTPHA MSSAAPPSQV YASTEVGRSH
     SEDSRSQSAL YVPTLSPTHA GYAIRGDEPS THRSDSNVMW REAGGGREQD EEDDLSTNYM
     PTAKTPQQVA PPTAAEFGDE EEEEQ
//

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