(data stored in SCRATCH3701 zone)

HOGENOM6: TROWT_1_PE6

ID   TROWT_1_PE6                          STANDARD;      PRT;   819 AA.
AC   TROWT_1_PE6; Q83H53;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (TROWT_1.PE6).
GN   Name=gyrA1; OrderedLocusNames=TWT006; ORFNames=TWT_006;
OS   TROPHERYMA WHIPPLEI STR. TWIST.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Micrococcineae; Tropheryma.
OX   NCBI_TaxID=203267;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS TROWT_1.PE6.
CC       Tropheryma whipplei str. Twist, complete genome.
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:Q83H53_TROWT
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q83H53; -.
DR   EMBL; AE014184; AAO44103.1; -; Genomic_DNA.
DR   RefSeq; NP_787134.1; NC_004572.3.
DR   HSSP; P09097; 1AB4.
DR   ProteinModelPortal; Q83H53; -.
DR   STRING; Q83H53; -.
DR   GeneID; 1482263; -.
DR   GenomeReviews; AE014184_GR; TWT006.
DR   KEGG; twh:TWT006; -.
DR   eggNOG; COG0188; -.
DR   OMA; EEYSAQG; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; TWHI203267:TW006-MONOMER; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; TROWT_1.PE6; -.
DR   PRODOM; TROWT_1_PE6.
DR   SWISS-2DPAGE; TROWT_1_PE6.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   819 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSEQNINQVD LREEMQRSYL DYAMSVIIGR ALPDVRDGLK PVHRRVLYAM YKGGYRPEKA
     FSKCARVVGD VMGQFHPHGD AAIYDALVRL VQPWAMRYPL AQGQGNFGSP GNDGAAAPRY
     TETKMATLAI EMVRDIDEDT VDFSPNYDGE SVEPTVMPCR FPNLLVNGSV GIAVGMATNI
     PPHNLAEVSA GALWCLENPD ATDEELTEAL LERIKGPDFP TGATVLDTGG IKDAYLTGRG
     SVVMRGVVDI EEIDGRTCLV VRELPYQVNP DNLALKIASL VKENKLSGIA DIRDETSGRT
     GQRLIIVLKR DAVARVVLNS LYKHTQLQEN FGVNMLAIVD GAPRTLSLCS FIRLWVEHQI
     EVIVRRTTFR LARAEQRAHI LRAYLRALDQ IDEVIQLIRS SKSAEEAQSN LMALLKIDET
     QARAILDLQL RRLAALERQR IISEAREIEE LISSFRKILS DKTAQCQVIA EELREIGQKH
     SDARRTEIIR GFDGSVSIED LIPVEPVVVV MTRCGYIKRT RIDQYRSQHR GGRGVKGAQV
     KADDVVLQFI STTTHNWLMF FTNTGRVYRA KAYEVPEASR EARGQHVANL LPLKPNEAVT
     RILSVSNFDS EDTSLVLATK DGYVKKTTLK EYDTSLSTGV IAIKLRPGDK LVSAVLARSD
     QDIILVTKNA RSLRFKSGTL RPLSRGSYGV KGISLRENDL LLSAELILSD DSYIFVVSER
     GYAKRSRVGD YKLQARGGIG VRVANITEQK GVLADMLVVN DDDEVLVILA SGKVIRSSVA
     EVSPTLRYTT GVVFVRMSDG DKILAMTIAE KCDDLEGQG
//

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