(data stored in SCRATCH3701 zone)

HOGENOM6: TSUPD_1_PE10

ID   TSUPD_1_PE10                         STANDARD;      PRT;   837 AA.
AC   TSUPD_1_PE10; D5UPB2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (TSUPD_1.PE10).
GN   OrderedLocusNames=Tpau_0010;
OS   TSUKAMURELLA PAUROMETABOLA DSM 20162.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Tsukamurellaceae; Tsukamurella.
OX   NCBI_TaxID=521096;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS TSUPD_1.PE10.
CC       Tsukamurella paurometabola DSM 20162 chromosome, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:D5UPB2_TSUPD
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D5UPB2; -.
DR   EMBL; CP001966; ADG76664.1; -; Genomic_DNA.
DR   RefSeq; YP_003645003.1; NC_014158.1.
DR   GeneID; 9154141; -.
DR   GenomeReviews; CP001966_GR; Tpau_0010.
DR   KEGG; tpr:Tpau_0010; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; TSUPD_1.PE10; -.
DR   PRODOM; TSUPD_1_PE10.
DR   SWISS-2DPAGE; TSUPD_1_PE10.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   837 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDTTPPTET GGHDRIEPVD IQQEMQRSYI DYAMSVIVGR ALPEVRDGMK PVQRRILYAS
     YDAGYRPDRS YVKSAKPVAE TMGNYHPHGD SAIYDALVRL AQPWSMRYPL IDGQGNFGSP
     GNDPAAAMRY TEARLTPLAM EMLRGIDQET VDFAPNYDGK TQEPTVLPAR VPNLLMNGSG
     GIAVGMATNI PPHNLREIAE AVFWCLENYD ADSEATLEAC MERVKGPDFP THGLIVGGQG
     IKDAYSTGRG SIRMRGVVEV EEDSKGATEL VITELPYQVN PDNLVLSIAE QVRDGKIAGI
     SKIEDQSSDR VGMRIVVRLK RDAVAKVVLN NLYKHSQLQT SFGANMLSIV DGVPRTLRLD
     QMIRYYVAHQ LDVIVRRTKF LLRKAEERAH ILRGLVKALD ALDEVIALIR ASQTTEIART
     GLMELLDVDE LQANAILDMQ LRKLAALERQ KIIDELAEIE REIADLKDIL DKPERQRAIV
     RDELGEIVEK FGDDRRTKII AADGDVTDED LIAREDVVVT ITETGYAKRT KTDLYRSQKR
     GGKGVKGADL KQDDIVRHFF VCSTHDWILF FTTKGRVYRA KAYELPEQSR TARGQHVANL
     LAFQPEERIA QVIQIKGYDD APYLVLATKN GLVKKSRLED FDSNRSGGIV AINLRDEDEL
     VGAALVSSED DLLLVSKNAQ SIRFSATDEA LRPMGRATSG VQGMRFNGDD QLLALNVVQE
     DTYLLVATSG GYAKRTAMDD YPVQGRGGKG VLTIQFDPKR GDLVGALIVN DETELYAITS
     GGGVIRTAAR QVRKAGRQTK GVRLMNLGEG TTLLAIARNA DETDETSDET EQATTEE
//

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