(data stored in SCRATCH3701 zone)

HOGENOM6: UREU1_1_PE88

ID   UREU1_1_PE88                         STANDARD;      PRT;   844 AA.
AC   UREU1_1_PE88; B5ZAR1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (UREU1_1.PE88).
GN   Name=gyrA; OrderedLocusNames=UUR10_0088;
OS   UREAPLASMA UREALYTICUM SEROVAR 10 STR. ATCC 33699.
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Ureaplasma.
OX   NCBI_TaxID=565575;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS UREU1_1.PE88.
CC       Ureaplasma urealyticum serovar 10 str. ATCC 33699 chromosome, complete
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:B5ZAR1_UREU1
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B5ZAR1; -.
DR   EMBL; CP001184; ACI60302.1; -; Genomic_DNA.
DR   RefSeq; YP_002284501.1; NC_011374.1.
DR   ProteinModelPortal; B5ZAR1; -.
DR   SMR; B5ZAR1; 47-503.
DR   STRING; B5ZAR1; -.
DR   GeneID; 6984108; -.
DR   GenomeReviews; CP001184_GR; UUR10_0088.
DR   KEGG; uue:UUR10_0088; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; UURE95664:UUR10_0088-MONOMER; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; UREU1_1.PE88; -.
DR   PRODOM; UREU1_1_PE88.
DR   SWISS-2DPAGE; UREU1_1_PE88.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   844 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MALKKPKKSR LTTEEIKQQL EGSTIKEQSI TKEVETSFLD YSMSVIVARA LPDVRDGFKP
     VHRRALFAAF ENGMTHDKPY KKSARWVGDV IGKYHPHGDQ AVYQTIVRMA QEFSMRYLLV
     DGHGNFGSID GDSAAAMRYT EARLSKISYE LLKYIDKETV DFVPNYDASE QEPSVLPSGF
     PNLLTNGTTG IAVGMATNIP PHNLTEVCQA IKAYAKNHDI SIPEIMEHLK GPDFPTGAEI
     YGDSGIINYF NTGRGSVTIR SKYEIEDIGQ GRVAIVVTEI PYMVNKVNLI EKIVELVTNK
     QIEGISDLRD ESSRDGIRIV IEVKRDVIPE VLLNKLFKTT ALQTNFSVNN LALVNGVPMV
     LNIKEMIKYY FEHQIEVLVR RTKFDLRKAK ERIHIVEGLV IAVNNIDEVI KIIKASGDDD
     IASKALIARF GLTELQTKAI LEMRLRALTG LNIDKLKKEY EDLLLIIEDL EDILENYDRQ
     VNIICENLDY LIEKFGDERR TEIMYGVSSH IDDEDLIPVE DIVVTMSKRG YFKRLPIDTY
     KNQRRGGVGV QGLKTYEDDD VEKILVANTH TDLLFFSDLG RVYRLRGHEV PLGSRQSKGI
     PAINFLPIEK SESILTILPI DNYEQGSLFF TTSKGIIKRA NLSDFESIRA NGKIAITLKE
     GDKLFSVMQT LGNDEVFIGA SNGNVIRFNE NDAREMGRIA TGVKGINLED DEYVVGTGLS
     SHGEYVLAVG SKGLGKLTDI NDYRLTKRGA KGVNTLKVND RTGNLVSIKV VNRDEEALII
     TTSGKVIRLS IQDISVIGRN TSGVKLISLE NKEEVKSIAI FKKEEIDDND DEQKTSHGNE
     HNLE
//

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