(data stored in SCRATCH3701 zone)

HOGENOM6: VIBCJ_2_PE2052

ID   VIBCJ_2_PE2052                       STANDARD;      PRT;   894 AA.
AC   VIBCJ_2_PE2052; C3NR44;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (VIBCJ_2.PE2052).
GN   OrderedLocusNames=VCD_003093;
OS   VIBRIO CHOLERAE MJ-1236.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=593588;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS VIBCJ_2.PE2052.
CC       Vibrio cholerae MJ-1236 chromosome 1, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:C3NR44_VIBCJ
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C3NR44; -.
DR   EMBL; CP001485; ACQ61253.1; -; Genomic_DNA.
DR   RefSeq; YP_002878823.1; NC_012668.1.
DR   ProteinModelPortal; C3NR44; -.
DR   SMR; C3NR44; 30-521, 535-865.
DR   STRING; C3NR44; -.
DR   GeneID; 7857331; -.
DR   GenomeReviews; CP001485_GR; VCD_003093.
DR   KEGG; vcj:VCD_003093; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; VIBCJ_2.PE2052; -.
DR   PRODOM; VIBCJ_2_PE2052.
DR   SWISS-2DPAGE; VIBCJ_2_PE2052.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   894 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSDLAKEITP VNIEDELRSS YLDYAMSVIV GRALPDVRDG LKPVHRRVLF AMNVLGNDWN
     KAYKKSARVV GDVIGKYHPH GDSAVYDTIV RMAQPFSLRY MLVDGQGNFG SIDGDSAAAM
     RYTEVRMSKI AHELLADLDK ETVDYVPNYD GTEQIPAVLP TKIPNLLING ASGIAVGMAT
     NIPPHNLGEV IDGCLAYIDN EAITIDELMD YIPGPDFPTA ALISGRKGII DAYKTGRGKV
     YMRSKAEIET DKNGKETIIV SEIPYQVNKA RLIEKIAELV KEKKVEGISA LRDESDKDGM
     RIVIECKRDA VGEVVLNNLY ANTQLQTTFG INMVALDNGQ PKLFNLKEML KCFVDHRREV
     VTRRTIFELR KARERAHILE GLALALANID EIIELIRRAA TPAEAKEGLI ARGWDLGNVA
     AMLERAGTDA ARPEWLEPQY GIRDGKYFLT EQQAQAILDL RLHKLTGLEH EKILDEYKQL
     LEEIAALMHI LASTERLMEV IREELEAIRA GFSDARRTEI TAATHDIDME ELIAREDVVV
     TLSHEGYVKY QLLSDYEAQR RGGKGKSATK MKEEDYIERL LVANTHDNIL LFSTRGKTYR
     MKVYQLPLAS RTARGKPIVN LLPLEENERI TAILPVTEFS EDKFIFMATG DGTVKKTSLD
     QFANVRANGL IALNLRDEDS LIGVDITDGE SEIMLFSKFG KVVRFKESEE TAVVDENGQP
     VLDENGQPEI KFKGVRPMGR TAAGVRGMKL ADGDQVVSLI VPKTEGDVLT VTENGYGKRT
     SLSEYPTKGR GTQGVVSIKV SERNGSVVGA VQVAEGDEFM MITNAGTLVR TRVAEVSQVG
     RNTQGVTLIR TSEGESVVGL QRIDEIEESE LPEGEEALVE NDAPVAQDDD GEQE
//

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