(data stored in SCRATCH3701 zone)

HOGENOM6: VIBF1_1_PE1203

ID   VIBF1_1_PE1203                       STANDARD;      PRT;   878 AA.
AC   VIBF1_1_PE1203; Q5E5J7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase (VIBF1_1.PE1203) (Type II topoisomerase),
DE   subunit A; EC=5.99.1 3; .
GN   Name=gyrA; OrderedLocusNames=VF_1204;
OS   VIBRIO FISCHERI ES114.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Aliivibrio.
OX   NCBI_TaxID=312309;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS VIBF1_1.PE1203.
CC       Vibrio fischeri ES114 chromosome I, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:Q5E5J7_VIBF1
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q5E5J7; -.
DR   EMBL; CP000020; AAW85699.1; -; Genomic_DNA.
DR   RefSeq; YP_204587.1; NC_006840.2.
DR   PDB; 3KUA; X-ray; 2.13 A; A/B=362-493.
DR   PDBsum; 3KUA; -.
DR   ProteinModelPortal; Q5E5J7; -.
DR   SMR; Q5E5J7; 30-520, 534-840.
DR   STRING; Q5E5J7; -.
DR   GeneID; 3278520; -.
DR   GenomeReviews; CP000020_GR; VF_1204.
DR   KEGG; vfi:VF_1204; -.
DR   NMPDR; fig|312309.3.peg.1052; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; Q5E5J7; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; VFIS312309:VF1204-MONOMER; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; VIBF1_1.PE1203; -.
DR   PRODOM; VIBF1_1_PE1203.
DR   SWISS-2DPAGE; VIBF1_1_PE1203.
KW   DNA gyrase (type II topoisomerase), subunit A;
KW   3D-structure; ATP-binding; Complete proteome; Cytoplasm; DNA-binding;
KW   Isomerase; Nucleotide-binding; Reference proteome; Topoisomerase.
SQ   SEQUENCE   878 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSDLAKEITP VNIEDELRGS YLDYAMSVIV GRALPDVRDG LKPVHRRVLF AMDVLGNDWN
     KPYKKSARVV GDVIGKYHPH GDSAVYDTIV RMAQPFSLRY MLVDGQGNFG SIDGDSAAAM
     RYTEVRMAKI AHELLADLDK ETVDYVPNYD GTEQIPAVLP TKIPNLLVNG SSGIAVGMAT
     NIPPHNLTEV VNGCLAFIEN EEITIDELMN YIPGPDFPTA ALISGRKGIV DAYKTGRGKV
     YMRSKANIEA DKNGKETIIV TEIPYQVNKA RLIEKIAELV KDKKVEGISA LRDESDKDGM
     RIVIECKRDA VGEVVLNNLY SLTQLQTTFG INMVALDNGQ PKLFNLKEML KCFVDHRREV
     VTRRTIFELR KARDRAHILE GLALALANID EIIELIKNAP TPAEAKEGLI SRGWDLGNVA
     SMLERAGTDA ARPDWLEPEF GIREGKYFLT EQQAQAILEL RLHRLTGLEH EKILDEYKAL
     LDEIAELMHI LASTERLMEV IRDELVMVRD MYGDERRTEI GAAIHDIDME DLITQEDVVV
     TLSREGYVKY QILSDYEAQR RGGKGKSATK MKDEDFIERL LVANTHDNIL CFSTRGKAYS
     LKVFQLPQAS RTARGKPIVN ILPLEEGERI TAILPVSEYS EDKFIFMATG DGTVKKTSLD
     QFAKVRANGL IAVNLREDDS LIGVDITDGS SEIMLFSKAG KVVRFNEEQV RGMGRTASGV
     RGMKLSGEDQ VVSLIVPSNE GDILTVTQNG YGKRTVLSEY PAKSRATQGV VSIKVSERNG
     SVVGAVQAED GDEFMMITDA GTLVRTRVSE VSQVGRNTQG VTLIRTSENE NVVALQRIDE
     VEEAEIIEGE EGEVTEATVT TEATDAPQAD TDAESTEE
//

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