(data stored in SCRATCH3701 zone)

HOGENOM6: VIVUL1_1_PE2762

ID   VIVUL1_1_PE2762                      STANDARD;      PRT;   852 AA.
AC   VIVUL1_1_PE2762; Q8D8E2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (VIVUL1_1.PE2762).
GN   Name=gyrA; OrderedLocusNames=VV1_3038;
OS   VIBRIO VULNIFICUS CMCP6.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=216895;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS VIVUL1_1.PE2762.
CC       Vibrio vulnificus CMCP6 chromosome I, complete genome.
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:Q8D8E2_VIBVU
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q8D8E2; -.
DR   EMBL; AE016795; AAO11362.2; -; Genomic_DNA.
DR   RefSeq; NP_761835.2; NC_004459.3.
DR   GeneID; 1179865; -.
DR   GenomeReviews; AE016795_GR; VV1_3038.
DR   KEGG; vvu:VV1_3038; -.
DR   BioCyc; VVUL216895:VV1_3038-MONOMER; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; VIVUL1_1.PE2762; -.
DR   PRODOM; VIVUL1_1_PE2762.
DR   SWISS-2DPAGE; VIVUL1_1_PE2762.
KW   Type IIA topoisomerase, A subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   852 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNVLGNDWNK PYKKSARVVG DVIGKYHPHG DSAVYDTIVR MAQPFSLRYM LVDGQGNFGS
     IDGDSAAAMR YTEVRMAKIA HELLADLDKE TVDYVPNYDG TEQIPAVLPT KIPNLLVNGS
     SGIAVGMATN IPPHNLTEVI DGCLAYINNE AITIDELMDY IPGPDFPTAA LISGRKGIID
     AYKTGRGKIY MRSKAEIEVE KNGKETIIVT EIPYQVNKAR LIEKIAELVK DKKVEGISAL
     RDESDKDGMR IVIECKRDAV GEVVLNNLYA QTQLQTTFGI NMVALDNGQP KLFNLKEMLK
     CFVDHRREVV TRRTIFELKK ARDRAHILEA LALALANIDE IIELIRNAAT PAEAKAGLVA
     RGWDLGNVAA MLESAGTDAA RPDWLEPQYG IRDGQYFLTE TQAQAILDLR LHKLTGLEHE
     KILDEYKALL DEIKELMHIL ASTERLMEVI REELEMVRDA FGDVRRTEIT AASHDIDLEE
     LIAREDVVVT LSHEGYVKYQ ILSDYEAQRR GGKGKSATKM KDEDYIERLL VANTHDNILL
     FSTRGKTYRL KVYQLPLASR TARGKPIVNL LPLEESERIT AILPVTEFSA DKFIFMATGD
     GTVKKTSLDQ FSNVRANGLI AVNLRDEDSL IGVDITDGES EIMLFSKFGK VVRFKEAEES
     PVLDENGNPA LDENGQPEIK FKGVRPMGRT AAGVRGMKLA DGDQVVSLIV PKNDGDVLTV
     TENGYGKRTV LSEYPTKGRG TQGVVSIKVS ERNGSVVGAV QVEDGDEFMM ITDAGTLVRT
     RVAEVSQVGR NTQGVTLIRT AEDESVVGLQ RIDEVEETEL PEGEEADATE ATEQAPQAQD
     PQADNDDAAD QE
//

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