(data stored in ACNUC7820 zone)

HOGENOM: XENTR1001_PE5

ID   XENTR1001_PE5                        STANDARD;      PRT;   582 AA.
AC   XENTR1001_PE5; B1H349;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   Flags: Fragments;
DE   RecName: Full=Transcription factor Sox-6;AltName: Full=SRY (XENTR1001.PE5)
DE   (sex determining region Y)-box 6; .
GN   Name=sox6;
OS   XENOPUS (SILURANA) TROPICALIS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amphibia; Batrachia; Anura; Mesobatrachia;
OC   Pipoidea; Pipidae; Xenopodinae; Xenopus.
OX   NCBI_TaxID=8364;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS XENTR1001.PE5.
CC       Xenopus tropicalis scaffold scaffold_1001 JGI4.1 full sequence 1..23008
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:SOX6_XENTR
CC   -!- FUNCTION: Transcriptional activator. Binds specifically to the DNA
CC       sequence 5'-AACAAT-3'. Plays a key role in several developmental
CC       processes, including neurogenesis and skeleton formation (By
CC       similarity).
CC   -!- SUBCELLULAR LOCATION: Nucleus (By similarity).
CC   -!- PTM: Sumoylation inhibits the transcriptional activity (By
CC       similarity).
CC   -!- SIMILARITY: Contains 1 HMG box DNA-binding domain.
CC   -!- GENE_FAMILY: HOG000056455 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Xenopus_tropicalis;ENSXETG00000016058;ENSXETT00000035026;ENSXETP00000035026.
DR   EMBL; BC161247; - ;
DR   UniProtKB/Swiss-Prot; B1H349; -.
DR   EMBL; BC161247; AAI61247.1; -; mRNA.
DR   RefSeq; NP_001116887.1; NM_001123415.1.
DR   UniGene; Str.35208; -.
DR   ProteinModelPortal; B1H349; -.
DR   SMR; B1H349; 568-637.
DR   STRING; B1H349; -.
DR   GeneID; 100144640; -.
DR   KEGG; xtr:100144640; -.
DR   CTD; 55553; -.
DR   Xenbase; XB-GENE-483934; sox6.
DR   eggNOG; veNOG06750; -.
DR   GeneTree; ENSGT00600000084111; -.
DR   Bgee; B1H349; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
DR   InterPro; IPR000910; HMG_HMG1/HMG2.
DR   InterPro; IPR009071; HMG_superfamily.
DR   Gene3D; G3DSA:1.10.30.10; HMG-box; 1.
DR   Pfam; PF00505; HMG_box; 1.
DR   SMART; SM00398; HMG; 1.
DR   SUPFAM; SSF47095; HMG-box; 1.
DR   PROSITE; PS50118; HMG_BOX_2; 1.
DR   HOGENOMDNA; XENTR1001.PE5; -.
KW   ENSXETG00000016058820036002503210000011;
KW   SOX6_XENTR; BC161247;
KW   Activator; Complete proteome; Developmental protein; DNA-binding;
KW   Isopeptide bond; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Ubl conjugation.
SQ   SEQUENCE   582 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     GTPESLAEKE RQLSTMITQL ISLREQLLAA HDEQKKLAAS QIEKQRQQMD LARQQQEQIA
     RQQQQLLQQQ HKINILQQQI QVQGHMPPLM IPIFPHDQRT LAAAAAAQQG FLFPPGLSYK
     PGDNYPMQFI PSTMAAAAAS GLSPLQLQQL YAAQLASMQV SPGAKIPTTP QPANAPGTLS
     PTGMKSEKRG TSPVAQIKED EAAQPLNLSA RPKTADPIKS PTSPTQSFFP VSKTSPVSLS
     NKSGIPSPIR GPSLDILSSL NSPALFGDQD TVMKAIQEAR KMREQIQREQ LLTPHSIDGK
     LPINNMGLNN CRSDKERTHF ENLGPQLTGK PNEDGKLGPG VIDLTRPEDV EGGATVVEAR
     VYRDTRGRSS SEPHIKRPMN AFMVWAKDER RKILQAFPDM HNSNISKILG SRWKAMSNQE
     KQPYYEEQAR LSKIHLEKYP NYKYKPRPKR TCIVDGKKLR IGEYKQLMRS RRQEMRQFFT
     VGQQPQIPIS TPTGVVYPGA ISMATTTPSP QMTSDCSSTS ASPEPSIPVI QSTYGMKLDS
     GSLGGNDLMN GEDEMEMYDD FEDDPKSDYS SDNEANEAVS AN
//

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