(data stored in ACNUC14238 zone)

HOGENOM: YEASTIII_PE104

ID   YEASTIII_PE104                       STANDARD;      PRT;   512 AA.
AC   YEASTIII_PE104; P25621; D6VR38;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Pantothenate transporter FEN2;AltName: Full=Fenpropimorph
DE   resistance protein 2; (YEASTIII.PE104).
GN   Name=FEN2; OrderedLocusNames=YCR028C; ORFNames=YCR28C;
OS   SACCHAROMYCES CEREVISIAE.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomyceta; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=4932;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS YEASTIII.PE104.
CC       Saccharomyces cerevisiae chromosome III EF2 full sequence 1..316617
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:FEN2_YEAST
CC   -!- FUNCTION: Transports pantothenate into the cell. Also involved in
CC       the catabolite repression-mediated regulation of ergosterol
CC       biosynthesis and in fenpropimorph resistance.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- MISCELLANEOUS: Present with 3060 molecules/cell in log phase SD
CC       medium.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       Allantoate permease family.
CC   -!- GENE_FAMILY: HOG000179304 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Saccharomyces_cerevisiae;YCR028C;YCR028C;YCR028C.
DR   EMBL; X59720; - ;
DR   UniProtKB/Swiss-Prot; P25621; D6VR38; -.
DR   EMBL; X59720; CAA42320.1; -; Genomic_DNA.
DR   EMBL; BK006937; DAA07507.1; -; Genomic_DNA.
DR   PIR; S19439; S19439.
DR   RefSeq; NP_009957.1; NM_001178743.1.
DR   ProteinModelPortal; P25621; -.
DR   DIP; DIP-7672N; -.
DR   IntAct; P25621; 1.
DR   MINT; MINT-1357147; -.
DR   STRING; P25621; -.
DR   TCDB; 2.A.1.14.18; major facilitator superfamily (MFS).
DR   EnsemblFungi; YCR028C; YCR028C; YCR028C.
DR   GeneID; 850394; -.
DR   KEGG; sce:YCR028C; -.
DR   NMPDR; fig|4932.3.peg.682; -.
DR   CYGD; YCR028c; -.
DR   SGD; S000000623; FEN2.
DR   eggNOG; fuNOG05390; -.
DR   GeneTree; EFGT00050000001200; -.
DR   OMA; VLASMNM; -.
DR   OrthoDB; EOG44QX8H; -.
DR   PhylomeDB; P25621; -.
DR   NextBio; 965917; -.
DR   ArrayExpress; P25621; -.
DR   Genevestigator; P25621; -.
DR   GermOnline; YCR028C; Saccharomyces cerevisiae.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IGI:SGD.
DR   GO; GO:0015233; F:pantothenate transmembrane transporter activity; IMP:SGD.
DR   GO; GO:0006897; P:endocytosis; IMP:SGD.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR016196; MFS_dom_general_subst_transpt.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; MFS_gen_substrate_transporter; 1.
DR   HOGENOMDNA; YEASTIII.PE104; -.
KW   YCR028C-A100026476820036002503210000011; YCR028C-A1; FEN2_YEAST; X59720;
KW   Cell membrane; Complete proteome; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
SQ   SEQUENCE   512 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MMKESKSITQ HEVERESVSS KRAIKKRLLL FKIDLFVLSF VCLQYWINYV DRVGFTNAYI
     SGMKEDLKMV GNDLTVSNTV FMIGYIVGMV PNNLMLLCVP PRIWLSFCTF AWGLLTLGMY
     KVTSFKHICA IRFFQALFES CTFSGTHFVL GSWYKEDELP IRSAIFTGSG LVGSMFSGFM
     QTSIFTHLNG RNGLAGWRWL FIIDFCITLP IAIYGFIFFP GLPDQTSAVS KFSMTRYIFN
     EQELHYARRR LPARDESTRL DWSTIPRVLK RWHWWMFSLV WVLGGENLGF ASNSTFALWL
     QNQKYTLAQR NNYPSGIFAV GIVSTLCSAV YMSKIPRARH WHVSVFISLV MVIVAVLIRA
     DPLNPKVVFS AQYLGGVAYA GQAVFFSWAN IICHADLQER AIVLASMNMF SGAVNAWWSI
     LFFASDMVPK FERGCYALLA TAISSGIVSV VIRSLQIKEN LSKKQVPYID ANDMPGEDDD
     DDNQDNENDG DDESMEVELH NEEMAEISNP FR
//

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