(data stored in ACNUC7421 zone)

HOGENOM: YEASTVII_PE264

ID   YEASTVII_PE264                       STANDARD;      PRT;   918 AA.
AC   YEASTVII_PE264; P05030; D6VUC9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Plasma membrane ATPase 1; EC=3.6.3 6;AltName: Full=Proton
DE   pump 1; (YEASTVII.PE264).
GN   Name=PMA1; OrderedLocusNames=YGL008C;
OS   SACCHAROMYCES CEREVISIAE.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomyceta; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=4932;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS YEASTVII.PE264.
CC       Saccharomyces cerevisiae chromosome VII EF2  sequence 1..1090947
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:PMA1_YEAST
CC   -!- FUNCTION: The plasma membrane ATPase of plants and fungi is a
CC       hydrogen ion pump. The proton gradient it generates drives the
CC       active transport of nutrients by H(+)-symport. The resulting
CC       external acidification and/or internal alkinization may mediate
CC       growth responses.
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O + H(+)(In) = ADP + phosphate +
CC       H(+)(Out).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- PTM: Phosphorylated on multiple Ser and Thr residues.
CC   -!- MISCELLANEOUS: There are two plasma membrane ATPases in yeast.
CC       This is the major isoform.
CC   -!- MISCELLANEOUS: Present with 1260000 molecules/cell in log phase SD
CC       medium.
CC   -!- SIMILARITY: Belongs to the cation transport ATPase (P-type)
CC       (TC 3.A.3) family. Type IIIA subfamily.
CC   -!- GENE_FAMILY: HOG000160005 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Saccharomyces_cerevisiae;YGL008C;YGL008C;YGL008C.
DR   EMBL; X03534; - ;
DR   EMBL; Z72530; - ;
DR   UniProtKB/Swiss-Prot; P05030; D6VUC9; -.
DR   EMBL; X03534; CAA27237.1; -; Genomic_DNA.
DR   EMBL; Z72530; CAA96708.1; -; Genomic_DNA.
DR   EMBL; BK006941; DAA08090.1; -; Genomic_DNA.
DR   PIR; S64010; PXBY1P.
DR   RefSeq; NP_011507.1; NM_001180873.1.
DR   ProteinModelPortal; P05030; -.
DR   SMR; P05030; 2-916.
DR   DIP; DIP-2537N; -.
DR   IntAct; P05030; 7.
DR   MINT; MINT-685556; -.
DR   STRING; P05030; -.
DR   TCDB; 3.A.3.3.6; P-type ATPase (P-ATPase) superfamily.
DR   PeptideAtlas; P05030; -.
DR   EnsemblFungi; YGL008C; YGL008C; YGL008C.
DR   GeneID; 852876; -.
DR   KEGG; sce:YGL008C; -.
DR   NMPDR; fig|4932.3.peg.2615; -.
DR   CYGD; YGL008c; -.
DR   SGD; S000002976; PMA1.
DR   eggNOG; fuNOG06156; -.
DR   GeneTree; EFGT00050000000742; -.
DR   OMA; YNAVEIL; -.
DR   OrthoDB; EOG4M68RQ; -.
DR   PhylomeDB; P05030; -.
DR   NextBio; 972514; -.
DR   ArrayExpress; P05030; -.
DR   Genevestigator; P05030; -.
DR   GermOnline; YGL008C; Saccharomyces cerevisiae.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0045121; C:membrane raft; IDA:SGD.
DR   GO; GO:0005739; C:mitochondrion; IDA:SGD.
DR   GO; GO:0005886; C:plasma membrane; IDA:SGD.
DR   GO; GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IDA:SGD.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006885; P:regulation of pH; IEP:SGD.
DR   InterPro; IPR008250; ATPase_P-typ_ATPase-assoc-dom.
DR   InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR   InterPro; IPR023300; ATPase_P-typ_cyto_domA.
DR   InterPro; IPR023299; ATPase_P-typ_cyto_domN.
DR   InterPro; IPR000695; ATPase_P-typ_H-transp.
DR   InterPro; IPR001757; ATPase_P-typ_ion-transptr.
DR   InterPro; IPR018303; ATPase_P-typ_P_site.
DR   InterPro; IPR006534; ATPase_P-typ_PM_proton-efflux.
DR   InterPro; IPR023298; ATPase_P-typ_TM_dom.
DR   InterPro; IPR005834; Dehalogen-like_hydro.
DR   InterPro; IPR023214; HAD-like_dom.
DR   Gene3D; G3DSA:2.70.150.10; ATPase_P-typ_cyto_domA; 2.
DR   Gene3D; G3DSA:3.40.1110.10; ATPase_P-typ_cyto_domN; 1.
DR   Gene3D; G3DSA:1.20.1110.10; ATPase_P-typ_TM_dom; 2.
DR   Pfam; PF00690; Cation_ATPase_N; 1.
DR   Pfam; PF00122; E1-E2_ATPase; 1.
DR   Pfam; PF00702; Hydrolase; 1.
DR   PRINTS; PR00119; CATATPASE.
DR   PRINTS; PR00120; HATPASE.
DR   SMART; SM00831; Cation_ATPase_N; 1.
DR   SUPFAM; SSF56784; HAD-like_dom; 1.
DR   TIGRFAMs; TIGR01647; ATPase-IIIA_H; 1.
DR   TIGRFAMs; TIGR01494; ATPase_P-type; 3.
DR   PROSITE; PS00154; ATPASE_E1_E2; 1.
DR   HOGENOMDNA; YEASTVII.PE264; -.
KW   YGL008C-A100026476820036002503210000011; YGL008C-A1; PMA1_YEAST; X03534;
KW   Z72530;
KW   ATP-binding; Cell membrane; Complete proteome;
KW   Direct protein sequencing; Hydrogen ion transport; Hydrolase;
KW   Ion transport; Isopeptide bond; Magnesium; Membrane; Metal-binding;
KW   Nucleotide-binding; Phosphoprotein; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport; Ubl conjugation.
SQ   SEQUENCE   918 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDTSSSSSS SSASSVSAHQ PTQEKPAKTY DDAASESSDD DDIDALIEEL QSNHGVDDED
     SDNDGPVAAG EARPVPEEYL QTDPSYGLTS DEVLKRRKKY GLNQMADEKE SLVVKFVMFF
     VGPIQFVMEA AAILAAGLSD WVDFGVICGL LMLNAGVGFV QEFQAGSIVD ELKKTLANTA
     VVIRDGQLVE IPANEVVPGD ILQLEDGTVI PTDGRIVTED CFLQIDQSAI TGESLAVDKH
     YGDQTFSSST VKRGEGFMVV TATGDNTFVG RAAALVNKAA GGQGHFTEVL NGIGIILLVL
     VIATLLLVWT ACFYRTNGIV RILRYTLGIT IIGVPVGLPA VVTTTMAVGA AYLAKKQAIV
     QKLSAIESLA GVEILCSDKT GTLTKNKLSL HEPYTVEGVS PDDLMLTACL AASRKKKGLD
     AIDKAFLKSL KQYPKAKDAL TKYKVLEFHP FDPVSKKVTA VVESPEGERI VCVKGAPLFV
     LKTVEEDHPI PEDVHENYEN KVAELASRGF RALGVARKRG EGHWEILGVM PCMDPPRDDT
     AQTVSEARHL GLRVKMLTGD AVGIAKETCR QLGLGTNIYN AERLGLGGGG DMPGSELADF
     VENADGFAEV FPQHKYRVVE ILQNRGYLVA MTGDGVNDAP SLKKADTGIA VEGATDAARS
     AADIVFLAPG LSAIIDALKT SRQIFHRMYS YVVYRIALSL HLEIFLGLWI AILDNSLDID
     LIVFIAIFAD VATLAIAYDN APYSPKPVKW NLPRLWGMSI ILGIVLAIGS WITLTTMFLP
     KGGIIQNFGA MNGIMFLQIS LTENWLIFIT RAAGPFWSSI PSWQLAGAVF AVDIIATMFT
     LFGWWSENWT DIVTVVRVWI WSIGIFCVLG GFYYEMSTSE AFDRLMNGKP MKEKKSTRSV
     EDFMAAMQRV STQHEKET
//

If you have problems or comments...

PBIL Back to PBIL home page