(data stored in ACNUC30567 zone)

HOGENOM: YEASTXIII_PE111

ID   YEASTXIII_PE111                      STANDARD;      PRT;   810 AA.
AC   YEASTXIII_PE111; P15274; D6VZE0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=AMP deaminase; EC=3.5.4 6;AltName: Full=Myoadenylate
DE   deaminase; (YEASTXIII.PE111).
GN   Name=AMD1; Synonyms=AMD; OrderedLocusNames=YML035C;
OS   SACCHAROMYCES CEREVISIAE.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomyceta; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=4932;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS YEASTXIII.PE111.
CC       Saccharomyces cerevisiae chromosome XIII EF2 full sequence 1..924429
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:AMPD_YEAST
CC   -!- FUNCTION: AMP deaminase plays a critical role in energy
CC       metabolism.
CC   -!- CATALYTIC ACTIVITY: AMP + H(2)O = IMP + NH(3).
CC   -!- COFACTOR: Binds 1 zinc ion per subunit (By similarity).
CC   -!- PATHWAY: Purine metabolism; IMP biosynthesis via salvage pathway;
CC       IMP from AMP: step 1/1.
CC   -!- SUBUNIT: Homotetramer.
CC   -!- INTERACTION:
CC       P33203:PRP40; NbExp=2; IntAct=EBI-2548, EBI-701;
CC   -!- MISCELLANEOUS: Present with 3910 molecules/cell in log phase SD
CC       medium.
CC   -!- SIMILARITY: Belongs to the adenosine and AMP deaminases family.
CC   -!- GENE_FAMILY: HOG000092200 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Saccharomyces_cerevisiae;YML035C;YML035C;YML035C.
DR   EMBL; M30449; - ;
DR   EMBL; Z46659; - ;
DR   UniProtKB/Swiss-Prot; P15274; D6VZE0; -.
DR   EMBL; M30449; AAA34420.1; -; Genomic_DNA.
DR   EMBL; Z46659; CAA86620.1; -; Genomic_DNA.
DR   EMBL; BK006946; DAA09864.1; -; Genomic_DNA.
DR   PIR; S49744; S49744.
DR   RefSeq; NP_013677.1; NM_001182392.1.
DR   ProteinModelPortal; P15274; -.
DR   SMR; P15274; 299-797.
DR   DIP; DIP-1949N; -.
DR   IntAct; P15274; 11.
DR   MINT; MINT-408221; -.
DR   STRING; P15274; -.
DR   PeptideAtlas; P15274; -.
DR   EnsemblFungi; YML035C; YML035C; YML035C.
DR   GeneID; 854973; -.
DR   KEGG; sce:YML035C; -.
DR   NMPDR; fig|4932.3.peg.4717; -.
DR   CYGD; YML035c; -.
DR   SGD; S000004498; AMD1.
DR   eggNOG; fuNOG04148; -.
DR   GeneTree; EFGT00050000003751; -.
DR   OMA; LQSGWEA; -.
DR   OrthoDB; EOG44XNR5; -.
DR   PhylomeDB; P15274; -.
DR   NextBio; 978079; -.
DR   ArrayExpress; P15274; -.
DR   Genevestigator; P15274; -.
DR   GermOnline; YML035C; Saccharomyces cerevisiae.
DR   GO; GO:0005737; C:cytoplasm; IDA:SGD.
DR   GO; GO:0003876; F:AMP deaminase activity; IDA:SGD.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006144; P:purine base metabolic process; IEA:InterPro.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
DR   InterPro; IPR006650; A/AMP_deam_AS.
DR   InterPro; IPR001365; A/AMP_deaminase.
DR   InterPro; IPR006329; AMP_deaminase.
DR   InterPro; IPR016297; AMP_deaminase_met.
DR   Pfam; PF00962; A_deaminase; 1.
DR   PIRSF; PIRSF001251; AMP_deaminase_met; 1.
DR   TIGRFAMs; TIGR01429; AMP_deaminase; 1.
DR   PROSITE; PS00485; A_DEAMINASE; 1.
DR   HOGENOMDNA; YEASTXIII.PE111; -.
KW   YML035C-A100026476820036002503210000011; YML035C-A1; AMPD_YEAST; M30449;
KW   Z46659;
KW   Complete proteome; Hydrolase; Metal-binding; Nucleotide metabolism;
KW   Phosphoprotein; Reference proteome; Zinc.
SQ   SEQUENCE   810 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDNQATQRLN DLSLEPAPSH DEQDGSGLVI DIDQRKIGDE QAGVVVDDET PPLEQQDSHE
     SLAADSRNAN FSYHENQQLL ENGTKQLALD EHDSHSAILE QPSHSTNCSS SNIAAMNKGH
     DSADHASQNS GGKPRTLSAS AQHILPETLK SFAGAPVVNK QVRTSASYKM GMLADDASQQ
     FLDDPSSELI DLYSKVAECR NLRAKYQTIS VQNDDQNPKN KPGWVVYPPP PKPSYNSDTK
     TVVPVTNKPD AEVFDFTKCE IPGEDPDWEF TLNDDDSYVV HRSGKTDELI AQIPTLRDYY
     LDLEKMISIS SDGPAKSFAY RRLQYLEARW NLYYLLNEYQ ETSVSKRNPH RDFYNVRKVD
     THVHHSACMN QKHLLRFIKH KLRHSKDEKV IFRDGKLLTL DEVFRSLHLT GYDLSIDTLD
     MHAHKDTFHR FDKFNLKYNP IGESRLREIF LKTNNYIKGT YLADITKQVI FDLENSKYQN
     CEYRISVYGR SLDEWDKLAS WVIDNKVISH NVRWLVQIPR LYDIYKKTGI VQSFQDICKN
     LFQPLFEVTK NPQSHPKLHV FLQRVIGFDS VDDESKVDRR FHRKYPKPSL WEAPQNPPYS
     YYLYYLYSNV ASLNQWRAKR GFNTLVLRPH CGEAGDPEHL VSAYLLAHGI SHGILLRKVP
     FVQYLYYLDQ VGIAMSPLSN NALFLTYDKN PFPRYFKRGL NVSLSTDDPL QFSYTREPLI
     EEYSVAAQIY KLSNVDMCEL ARNSVLQSGW EAQIKKHWIG KDFDKSGVEG NDVVRTNVPD
     IRINYRYDTL STELELVNHF ANFKRTIEEK
//

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