(data stored in ACNUC3476 zone)

HOGENOM: YEASTXIV_PE250

ID   YEASTXIV_PE250                       STANDARD;      PRT;   713 AA.
AC   YEASTXIV_PE250; P50944; D6W178;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Vacuolar amino acid transporter 4; (YEASTXIV.PE250).
GN   Name=AVT4; OrderedLocusNames=YNL101W; ORFNames=N2185;
OS   SACCHAROMYCES CEREVISIAE.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomyceta; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=4932;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS YEASTXIV.PE250.
CC       Saccharomyces cerevisiae chromosome XIV EF2 full sequence 1..784334
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:AVT4_YEAST
CC   -!- FUNCTION: Involved in amino acid efflux from the vacuole to the
CC       cytoplasm. Capable of transporting large neutral amino acids
CC       including tyrosine, glutamine, asparagine, isoleucine and leucine.
CC   -!- SUBCELLULAR LOCATION: Vacuole membrane; Multi-pass membrane
CC       protein.
CC   -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2
CC       family.
CC   -!- GENE_FAMILY: HOG000185918 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Saccharomyces_cerevisiae;YNL101W;YNL101W;YNL101W.
DR   EMBL; DQ115393; - ;
DR   EMBL; Z50161; - ;
DR   EMBL; Z71377; - ;
DR   UniProtKB/Swiss-Prot; P50944; D6W178; -.
DR   EMBL; Z50161; CAA90525.1; -; Genomic_DNA.
DR   EMBL; Z71377; CAA95977.1; -; Genomic_DNA.
DR   EMBL; BK006947; DAA10444.1; -; Genomic_DNA.
DR   PIR; S58251; S58251.
DR   RefSeq; NP_014298.1; NM_001182939.1.
DR   ProteinModelPortal; P50944; -.
DR   DIP; DIP-6754N; -.
DR   IntAct; P50944; 1.
DR   MINT; MINT-671686; -.
DR   STRING; P50944; -.
DR   EnsemblFungi; YNL101W; YNL101W; YNL101W.
DR   GeneID; 855622; -.
DR   KEGG; sce:YNL101W; -.
DR   NMPDR; fig|4932.3.peg.5369; -.
DR   CYGD; YNL101w; -.
DR   SGD; S000005045; AVT4.
DR   eggNOG; fuNOG04131; -.
DR   OMA; FLEFLYV; -.
DR   OrthoDB; EOG4R2731; -.
DR   PhylomeDB; P50944; -.
DR   NextBio; 979816; -.
DR   ArrayExpress; P50944; -.
DR   Genevestigator; P50944; -.
DR   GermOnline; YNL101W; Saccharomyces cerevisiae.
DR   GO; GO:0000329; C:fungal-type vacuole membrane; IMP:SGD.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015186; F:L-glutamine transmembrane transporter activity; IMP:SGD.
DR   GO; GO:0015188; F:L-isoleucine transmembrane transporter activity; IMP:SGD.
DR   GO; GO:0005302; F:L-tyrosine transmembrane transporter activity; IMP:SGD.
DR   GO; GO:0032974; P:amino acid export from vacuole; IMP:SGD.
DR   InterPro; IPR013057; AA_transpt_TM.
DR   Pfam; PF01490; Aa_trans; 1.
DR   HOGENOMDNA; YEASTXIV.PE250; -.
KW   YNL101W-A100026476820036002503210000011; YNL101W-A1; AVT4_YEAST;
KW   DQ115393; Z50161; Z71377;
KW   Amino-acid transport; Complete proteome; Membrane; Phosphoprotein;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport;
KW   Vacuole.
SQ   SEQUENCE   713 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MVTNNGDGEH LGIRRNGNLR HPSNNMKIPR RAQSTVLNSN PFYSRKYSMS TLTPRDICRS
     VDSRVFVDMS SPNFQTLEDP HRDEIINSVR LNYLNSSKRS SVSHGNEAIP RVNPTKNSSA
     STIAAANVDS DDDETNLSSA GGDITHDIYK LVKAEDPKRL RRPRSMENVT PKIEHHTKLS
     SASGLNVPGG FRREFIVNKK RQEHQLNDSA SSDFTSHESD SINQSSPSSN QDIDKVPFLT
     RNFLEFLYVF GHFAGESFED DFIPDSSNMM IRGEDERSAL LSRPDHMKVL PSAKGTTSTK
     KVFLILLKSF IGTGVLFLPN AFHNGGLFFS VSMLAFFGIY SYWCYYILVQ AKSSCGVSSF
     GDIGLKLYGP WMRIIILFSL VITQVGFSGA YMIFTAKNLQ AFLDNVFHVG VLPLSYLMVF
     QTIIFIPLSF IRNISKLSLP SLLANFFIMA GLVIVIIFTA KRLFFDLMGT PAMGVVYGLN
     ADRWTLFIGT AIFAFEGIGL IIPVQDSMRN PEKFPLVLAL VILTATILFI SIATLGYLAY
     GSNVQTVILL NLPQSNIFVN LIQLFYSIAI MLSTPLQLFP AIKIIENKFF PKFTKIYVKH
     DDLTTRVELR PNSGKLNWKI KWLKNFIRSI IVIIVVSIAY FGSDNLDKFV SVIGSLACIP
     LVYIYPSMLH LRGNSLPETK GEFWRFKPML DTILIFFGIA SMLYTSYQSI FGV
//

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