(data stored in ACNUC8465 zone)

HOGENOM: YEASTXI_PE295

ID   YEASTXI_PE295                        STANDARD;      PRT;   291 AA.
AC   YEASTXI_PE295; Q00246; D6VXB6; P30618;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=GTP-binding protein RHO4;Flags: Precursor; (YEASTXI.PE295).
GN   Name=RHO4; OrderedLocusNames=YKR055W;
OS   SACCHAROMYCES CEREVISIAE.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomyceta; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=4932;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS YEASTXI.PE295.
CC       Saccharomyces cerevisiae chromosome XI EF2 full sequence 1..666454
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:RHO4_YEAST
CC   -!- FUNCTION: Plays an important role in cell growth. Required to keep
CC       the uninucleated state. May be involved in the organization of the
CC       cytoskeleton which affects microtubule functions. Most likely RHO3
CC       and RHO4 of S.cerevisiae regulate partially overlapping but
CC       different pathways.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor; Cytoplasmic
CC       side (Potential).
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rho family.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA78500.1; Type=Frameshift; Positions=263; Note=Leads to a fusion with RNC1;
CC   -!- GENE_FAMILY: HOG000233974 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Saccharomyces_cerevisiae;YKR055W;YKR055W;YKR055W.
DR   EMBL; AY557909; - ;
DR   EMBL; D10007; - ;
DR   EMBL; Z14126; - ;
DR   EMBL; Z25734; - ;
DR   EMBL; Z28280; - ;
DR   UniProtKB/Swiss-Prot; Q00246; D6VXB6; P30618; -.
DR   EMBL; Z25734; CAA81020.1; -; Genomic_DNA.
DR   EMBL; D10007; BAA00898.1; -; Genomic_DNA.
DR   EMBL; Z14126; CAA78500.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; Z28280; CAA82133.1; -; Genomic_DNA.
DR   EMBL; AY557909; AAS56235.1; -; Genomic_DNA.
DR   EMBL; BK006944; DAA09206.1; -; Genomic_DNA.
DR   PIR; S37743; S37743.
DR   RefSeq; NP_012981.1; NM_001179845.1.
DR   ProteinModelPortal; Q00246; -.
DR   SMR; Q00246; 70-239.
DR   DIP; DIP-755N; -.
DR   IntAct; Q00246; 4.
DR   MINT; MINT-390167; -.
DR   STRING; Q00246; -.
DR   PeptideAtlas; Q00246; -.
DR   EnsemblFungi; YKR055W; YKR055W; YKR055W.
DR   GeneID; 853929; -.
DR   KEGG; sce:YKR055W; -.
DR   NMPDR; fig|4932.3.peg.3967; -.
DR   CYGD; YKR055w; -.
DR   SGD; S000001763; RHO4.
DR   GeneTree; EFGT00070000008719; -.
DR   OMA; VTNIEGP; -.
DR   OrthoDB; EOG4STWDX; -.
DR   PhylomeDB; Q00246; -.
DR   NextBio; 975294; -.
DR   ArrayExpress; Q00246; -.
DR   Genevestigator; Q00246; -.
DR   GermOnline; YKR055W; Saccharomyces cerevisiae.
DR   GO; GO:0005935; C:cellular bud neck; IDA:SGD.
DR   GO; GO:0005622; C:intracellular; IEA:InterPro.
DR   GO; GO:0005624; C:membrane fraction; IDA:SGD.
DR   GO; GO:0005886; C:plasma membrane; IDA:SGD.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:SGD.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030011; P:maintenance of cell polarity; IGI:SGD.
DR   GO; GO:0090337; P:regulation of formin-nucleated actin cable assembly; IPI:SGD.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   InterPro; IPR003578; Small_GTPase_Rho.
DR   Pfam; PF00071; Ras; 1.
DR   PRINTS; PR00449; RASTRNSFRMNG.
DR   SMART; SM00174; RHO; 1.
DR   TIGRFAMs; TIGR00231; Small_GTP; 1.
DR   PROSITE; PS51420; RHO; 1.
DR   HOGENOMDNA; YEASTXI.PE295; -.
KW   YKR055W-A100026476820036002503210000011; YKR055W-A1; RHO4_YEAST;
KW   D10007; Z14126; Z25734; Z28280;
KW   Cell membrane; Complete proteome; Direct protein sequencing;
KW   GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding;
KW   Phosphoprotein; Prenylation; Reference proteome.
SQ   SEQUENCE   291 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNTLLFKRKG GNCGNESNIV SQGSPSSSNL PESPGTLDEK NLPRLPTPFA RSLSTIPSYE
     QMKRTNKLPD YHLKIVVVGD GAVGKTCLLI SYVQGTFPTD YIPTIFENYV TNIEGPNGQI
     IELALWDTAG QEEYSRLRPL SYTNADVLMV CYSVGSKTSL KNVEDLWFPE VKHFCPSTPI
     MLVGLKSDLY EADNLSDLVE PSSAESLAKR LGAFAHIQCS ARLKENIDEV FETAIHTLLS
     DSLYAPREPT HTIKNPFKRN TTRSDIDSST GDTSVSISGT KRLRKNKCII M
//

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