(data stored in ACNUC3476 zone)

HOGENOM: YEASTXI_PE81

ID   YEASTXI_PE81                         STANDARD;      PRT;   692 AA.
AC   YEASTXI_PE81; P36062; D6VX50;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Vacuolar amino acid transporter 3; (YEASTXI.PE81).
GN   Name=AVT3; OrderedLocusNames=YKL146W; ORFNames=YKL600;
OS   SACCHAROMYCES CEREVISIAE.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomyceta; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=4932;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS YEASTXI.PE81.
CC       Saccharomyces cerevisiae chromosome XI EF2 full sequence 1..666454
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:AVT3_YEAST
CC   -!- FUNCTION: Involved in amino acid efflux from the vacuole to the
CC       cytoplasm. Capable of transporting large neutral amino acids
CC       including tyrosine, glutamine, asparagine, isoleucine and leucine.
CC   -!- SUBCELLULAR LOCATION: Vacuole membrane; Multi-pass membrane
CC       protein.
CC   -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2
CC       family.
CC   -!- GENE_FAMILY: HOG000185918 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Saccharomyces_cerevisiae;YKL146W;YKL146W;YKL146W.
DR   EMBL; Z26877; - ;
DR   EMBL; Z28146; - ;
DR   UniProtKB/Swiss-Prot; P36062; D6VX50; -.
DR   EMBL; Z26877; CAA81508.1; -; Genomic_DNA.
DR   EMBL; Z28146; CAA81988.1; -; Genomic_DNA.
DR   EMBL; BK006944; DAA09016.1; -; Genomic_DNA.
DR   PIR; S37976; S37976.
DR   RefSeq; NP_012776.1; NM_001179712.1.
DR   ProteinModelPortal; P36062; -.
DR   DIP; DIP-4105N; -.
DR   MINT; MINT-542142; -.
DR   STRING; P36062; -.
DR   TCDB; 2.A.18.7.1; amino acid/auxin permease (AAAP) family.
DR   EnsemblFungi; YKL146W; YKL146W; YKL146W.
DR   GeneID; 853710; -.
DR   KEGG; sce:YKL146W; -.
DR   NMPDR; fig|4932.3.peg.3755; -.
DR   CYGD; YKL146w; -.
DR   SGD; S000001629; AVT3.
DR   eggNOG; fuNOG04131; -.
DR   GeneTree; EFGT00050000001667; -.
DR   OMA; PGGFRRN; -.
DR   OrthoDB; EOG4R2731; -.
DR   PhylomeDB; P36062; -.
DR   NextBio; 974716; -.
DR   ArrayExpress; P36062; -.
DR   Genevestigator; P36062; -.
DR   GermOnline; YKL146W; Saccharomyces cerevisiae.
DR   GO; GO:0000329; C:fungal-type vacuole membrane; IMP:SGD.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015186; F:L-glutamine transmembrane transporter activity; IMP:SGD.
DR   GO; GO:0015188; F:L-isoleucine transmembrane transporter activity; IMP:SGD.
DR   GO; GO:0005302; F:L-tyrosine transmembrane transporter activity; IMP:SGD.
DR   GO; GO:0032974; P:amino acid export from vacuole; IMP:SGD.
DR   InterPro; IPR013057; AA_transpt_TM.
DR   Pfam; PF01490; Aa_trans; 1.
DR   HOGENOMDNA; YEASTXI.PE81; -.
KW   YKL146W-A100026476820036002503210000011; YKL146W-A1; AVT3_YEAST; Z26877;
KW   Z28146;
KW   Amino-acid transport; Complete proteome; Membrane; Phosphoprotein;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport;
KW   Vacuole.
SQ   SEQUENCE   692 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNGKEVSSGS GRTQSNNNKK NNNGGSTGIS HASGSPLTDG NGGNSNGNSR SRSRSRKSSG
     TTGGLLKKPP LLVNNEAVHA SVPDASHTSC NNGTLEVSIN NPEPHVVDAV ARHLIRNPSN
     SLQLQGGDIT RDLYKWTNDH PSSPSQYQYP SQPALSTSIP SQAPSFSNRK RSMSFSAASI
     ASSSHLNNNS EANGNPLAAI GLAPAPMTHE EIRAPGGFRR SFIIQKRRKH NVDAPIPNFF
     TRNFIEFLTL YGHFAGEDLS EEEEEEEETE EEPEEEALET ESTQLVSREH GRHPHKSSTV
     KAVLLLLKSF VGTGVLFLPK AFHNGGWGFS ALCLLSCALI SYGCFVSLIT TKDKVGVDGY
     GDMGRILYGP KMKFAILSSI ALSQIGFSAA YTVFTATNLQ VFSENFFHLK PGSISLATYI
     FAQVLIFVPL SLTRNIAKLS GTALIADLFI LLGLVYVYVY SIYYIAVNGV ASDTMLMFNK
     ADWSLFIGTA IFTFEGIGLL IPIQESMKHP KHFRPSLSAV MCIVAVIFIS CGLLCYAAFG
     SDVKTVVLLN FPQDTSYTLT VQLLYALAIL LSTPLQLFPA IRILENWTFP SNASGKYNPK
     VKWLKNYFRC AIVVLTSILA WVGANDLDKF VSLVGSFACI PLIYIYPPLL HYKASILSGT
     SRARLLLDLI VIVFGVAVMA YTSWQTIKMW SQ
//

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