(data stored in ACNUC7421 zone)

HOGENOM: YEASTXVI_PE260

ID   YEASTXVI_PE260                       STANDARD;      PRT;   947 AA.
AC   YEASTXVI_PE260; P19657; D6W3X8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Plasma membrane ATPase 2; EC=3.6.3 6;AltName: Full=Proton
DE   pump 2; (YEASTXVI.PE260).
GN   Name=PMA2; OrderedLocusNames=YPL036W;
OS   SACCHAROMYCES CEREVISIAE.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomyceta; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=4932;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS YEASTXVI.PE260.
CC       Saccharomyces cerevisiae chromosome XVI EF2 full sequence 1..948062
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:PMA2_YEAST
CC   -!- FUNCTION: The plasma membrane ATPase of plants and fungi is a
CC       hydrogen ion pump. The proton gradient it generates drives the
CC       active transport of nutrients by H(+)-symport. The resulting
CC       external acidification and/or internal alkinization may mediate
CC       growth responses.
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O + H(+)(In) = ADP + phosphate +
CC       H(+)(Out).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- MISCELLANEOUS: There are two plasma membrane ATPases in yeast.
CC       This is the minor isoform.
CC   -!- SIMILARITY: Belongs to the cation transport ATPase (P-type)
CC       (TC 3.A.3) family. Type IIIA subfamily.
CC   -!- GENE_FAMILY: HOG000160005 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Saccharomyces_cerevisiae;YPL036W;YPL036W;YPL036W.
DR   EMBL; J04421; - ;
DR   EMBL; U44030; - ;
DR   UniProtKB/Swiss-Prot; P19657; D6W3X8; -.
DR   EMBL; J04421; AAA83387.1; -; Genomic_DNA.
DR   EMBL; U44030; AAB68184.1; -; Genomic_DNA.
DR   EMBL; BK006949; DAA11394.1; -; Genomic_DNA.
DR   PIR; S62039; PXBY2P.
DR   RefSeq; NP_015289.1; NM_001183850.1.
DR   ProteinModelPortal; P19657; -.
DR   DIP; DIP-4036N; -.
DR   IntAct; P19657; 3.
DR   MINT; MINT-485284; -.
DR   STRING; P19657; -.
DR   PeptideAtlas; P19657; -.
DR   EnsemblFungi; YPL036W; YPL036W; YPL036W.
DR   GeneID; 856071; -.
DR   KEGG; sce:YPL036W; -.
DR   NMPDR; fig|4932.3.peg.6423; -.
DR   CYGD; YPL036w; -.
DR   SGD; S000005957; PMA2.
DR   eggNOG; fuNOG06156; -.
DR   GeneTree; EFGT00050000000742; -.
DR   OrthoDB; EOG47DDQ8; -.
DR   PhylomeDB; P19657; -.
DR   NextBio; 981065; -.
DR   ArrayExpress; P19657; -.
DR   Genevestigator; P19657; -.
DR   GermOnline; YPL036W; Saccharomyces cerevisiae.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005739; C:mitochondrion; IDA:SGD.
DR   GO; GO:0005886; C:plasma membrane; IDA:SGD.
DR   GO; GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IDA:SGD.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006885; P:regulation of pH; IEP:SGD.
DR   InterPro; IPR008250; ATPase_P-typ_ATPase-assoc-dom.
DR   InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR   InterPro; IPR023300; ATPase_P-typ_cyto_domA.
DR   InterPro; IPR023299; ATPase_P-typ_cyto_domN.
DR   InterPro; IPR000695; ATPase_P-typ_H-transp.
DR   InterPro; IPR001757; ATPase_P-typ_ion-transptr.
DR   InterPro; IPR018303; ATPase_P-typ_P_site.
DR   InterPro; IPR006534; ATPase_P-typ_PM_proton-efflux.
DR   InterPro; IPR023298; ATPase_P-typ_TM_dom.
DR   InterPro; IPR005834; Dehalogen-like_hydro.
DR   InterPro; IPR023214; HAD-like_dom.
DR   Gene3D; G3DSA:2.70.150.10; ATPase_P-typ_cyto_domA; 2.
DR   Gene3D; G3DSA:3.40.1110.10; ATPase_P-typ_cyto_domN; 2.
DR   Gene3D; G3DSA:1.20.1110.10; ATPase_P-typ_TM_dom; 2.
DR   Pfam; PF00690; Cation_ATPase_N; 1.
DR   Pfam; PF00122; E1-E2_ATPase; 1.
DR   Pfam; PF00702; Hydrolase; 1.
DR   PRINTS; PR00119; CATATPASE.
DR   PRINTS; PR00120; HATPASE.
DR   SMART; SM00831; Cation_ATPase_N; 1.
DR   SUPFAM; SSF56784; HAD-like_dom; 1.
DR   TIGRFAMs; TIGR01647; ATPase-IIIA_H; 1.
DR   TIGRFAMs; TIGR01494; ATPase_P-type; 3.
DR   PROSITE; PS00154; ATPASE_E1_E2; 1.
DR   HOGENOMDNA; YEASTXVI.PE260; -.
KW   YPL036W-A100026476820036002503210000011; YPL036W-A1; PMA2_YEAST; J04421;
KW   U44030;
KW   ATP-binding; Cell membrane; Complete proteome; Hydrogen ion transport;
KW   Hydrolase; Ion transport; Magnesium; Membrane; Metal-binding;
KW   Nucleotide-binding; Phosphoprotein; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
SQ   SEQUENCE   947 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSSTEAKQYK EKPSKEYLHA SDGDDPANNS AASSSSSSST STSASSSAAA VPRKAAAASA
     ADDSDSDEDI DQLIDELQSN YGEGDESGEE EVRTDGVHAG QRVVPEKDLS TDPAYGLTSD
     EVARRRKKYG LNQMAEENES LIVKFLMFFV GPIQFVMEAA AILAAGLSDW VDVGVICALL
     LLNASVGFIQ EFQAGSIVDE LKKTLANTAT VIRDGQLIEI PANEVVPGEI LQLESGTIAP
     ADGRIVTEDC FLQIDQSAIT GESLAAEKHY GDEVFSSSTV KTGEAFMVVT ATGDNTFVGR
     AAALVGQASG VEGHFTEVLN GIGIILLVLV IATLLLVWTA CFYRTVGIVS ILRYTLGITI
     IGVPVGLPAV VTTTMAVGAA YLAKKQAIVQ KLSAIESLAG VEILCSDKTG TLTKNKLSLH
     EPYTVEGVSP DDLMLTACLA ASRKKKGLDA IDKAFLKSLI EYPKAKDALT KYKVLEFHPF
     DPVSKKVTAV VESPEGERIV CVKGAPLFVL KTVEEDHPIP EDVHENYENK VAELASRGFR
     ALGVARKRGE GHWEILGVMP CMDPPRDDTA QTINEARNLG LRIKMLTGDA VGIAKETCRQ
     LGLGTNIYNA ERLGLGGGGD MPGSELADFV ENADGFAEVF PQHKYRVVEI LQNRGYLVAM
     TGDGVNDAPS LKKADTGIAV EGATDAARSA ADIVFLAPGL SAIIDALKTS RQIFHRMYSY
     VVYRIALSLH LEIFLGLWIA ILNNSLDINL IVFIAIFADV ATLTIAYDNA PYAPEPVKWN
     LPRLWGMSII LGIVLAIGSW ITLTTMFLPN GGIIQNFGAM NGVMFLQISL TENWLIFVTR
     AAGPFWSSIP SWQLAGAVFA VDIIATMFTL FGWWSENWTD IVSVVRVWIW SIGIFCVLGG
     FYYIMSTSQA FDRLMNGKSL KEKKSTRSVE DFMAAMQRVS TQHEKSS
//

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