(data stored in ACNUC13767 zone)

HOGENOM: YEPES2_1_PE4037

ID   YEPES2_1_PE4037                      STANDARD;      PRT;   609 AA.
AC   YEPES2_1_PE4037; Q8Z9S8; Q0W9R9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Glucosamine--fructose-6-phosphate aminotransferase
DE   (YEPES2_1.PE4037) [isomerizing]; EC=2.6.1 16;AltName:
DE   Full=D-fructose-6-phosphate amidotransferase;AltName: Full=GFAT;AltName:
DE   Full=Glucosamine-6-phosphate synthase;AltName: Full=Hexosephosphate
DE   aminotransferase;AltName: Full=L-glutamine-D-fructose-6-phosphate
DE   amidotransferase; .
GN   Name=glmS; OrderedLocusNames=YPO4118, y4132, YP_4025;
OS   YERSINIA PESTIS KIM 10.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Yersinia.
OX   NCBI_TaxID=187410;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS YEPES2_1.PE4037.
CC       Yersinia pestis KIM 10 chromosome, complete genome.
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:GLMS_YERPE
CC   -!- FUNCTION: Catalyzes the first step in hexosamine metabolism,
CC       converting fructose-6P into glucosamine-6P using glutamine as a
CC       nitrogen source (By similarity).
CC   -!- CATALYTIC ACTIVITY: L-glutamine + D-fructose 6-phosphate = L-
CC       glutamate + D-glucosamine 6-phosphate.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Contains 1 glutamine amidotransferase type-2 domain.
CC   -!- SIMILARITY: Contains 2 SIS domains.
CC   -!- GENE_FAMILY: HOG000258898 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q8Z9S8; Q0W9R9; -.
DR   EMBL; AL590842; CAL22686.1; -; Genomic_DNA.
DR   EMBL; AE009952; AAM87674.1; -; Genomic_DNA.
DR   EMBL; AE017042; AAS64164.1; -; Genomic_DNA.
DR   PIR; AB0500; AB0500.
DR   RefSeq; NP_671423.1; NC_004088.1.
DR   RefSeq; NP_995287.1; NC_005810.1.
DR   RefSeq; YP_002348969.1; NC_003143.1.
DR   ProteinModelPortal; Q8Z9S8; -.
DR   SMR; Q8Z9S8; 2-609.
DR   IntAct; Q8Z9S8; 1.
DR   GeneID; 1149079; -.
DR   GeneID; 1176946; -.
DR   GeneID; 2766761; -.
DR   GenomeReviews; AE009952_GR; y4132.
DR   GenomeReviews; AE017042_GR; YP_4025.
DR   GenomeReviews; AL590842_GR; YPO4118.
DR   KEGG; ype:YPO4118; -.
DR   KEGG; ypk:y4132; -.
DR   KEGG; ypm:YP_4025; -.
DR   OMA; YWFEALA; -.
DR   ProtClustDB; PRK00331; -.
DR   BioCyc; YPES187410:Y4132-MON; -.
DR   BioCyc; YPES214092:YPO4118-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004360; F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity; IEA:EC.
DR   GO; GO:0005529; F:sugar binding; IEA:InterPro.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00164; GlmS; 1; -.
DR   InterPro; IPR000583; GATase_2.
DR   InterPro; IPR017932; GATase_II.
DR   InterPro; IPR005855; GlmS_trans.
DR   InterPro; IPR001347; SIS.
DR   Pfam; PF00310; GATase_2; 2.
DR   Pfam; PF01380; SIS; 2.
DR   TIGRFAMs; TIGR01135; GlmS; 1.
DR   PROSITE; PS51278; GATASE_TYPE_2; 1.
DR   PROSITE; PS51464; SIS; 2.
DR   HOGENOMDNA; YEPES2_1.PE4037; -.
KW   Aminotransferase; Complete proteome; Cytoplasm;
KW   Glutamine amidotransferase; Reference proteome; Repeat; Transferase.
SQ   SEQUENCE   609 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MCGIVGAVAQ RDIAEILIEG LRRLEYRGYD SAGLAVVDSE GHLTRLRRVG KVHALSDAAE
     KQDLHGGTGI AHTRWATHGE PSEANAHPHV SDYISVVHNG IIENHEPLRE LLISRGYRFS
     SETDTEVIAH LVHWEQQQGG SLLEVVKRVI PQLRGAYGTV VMDSRDPSRL IAARSGSPLV
     IGCGVGENFI ASDQLALLPV TRRFIFLEEG DVVEVTRRSI SIFDKQGNAI ERPEIESQVQ
     YDAGDKGIYR HYMQKEIYEQ PMAIKNTLEG RLSHGMIDLS ELGPKADALL AEVQHIQIIA
     CGTSYNSGMV SRYWFESLAG VPCDVEIASE FRYRKSAVRP NSLLITLSQS GETADTLAAL
     RLSKELGYLG SLAICNVAGS SLVRESDLAL MTKAGTEIGV ASTKAFTTQL TVLLMLVGRI
     GKLKGADASL EHDIVHALQA LPARIEQMLS LDKTIEALAE GFSDKHHALF LGRGDQYPIA
     MEGALKLKEI SYIHAEAYAA GELKHGPLAL IDADMPVIVV APNNELLEKL KSNIEEVRAR
     GGLLYVFADQ DAGFTDSEGM KIIQLPHVEE IIAPIFYTVP LQLLSYHVAL IKGTDVDQPR
     NLAKSVTVE
//

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