(data stored in ACNUC9435 zone)

HOGENOM: YEPSE1_1_PE1

ID   YEPSE1_1_PE1                         STANDARD;      PRT;   732 AA.
AC   YEPSE1_1_PE1; Q05608; Q663G6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Protein kinase ypkA; Short=Protein kinase A; EC=2.7.11
DE   1;AltName: Full=Targeted effector protein kinase;Flags: Precursor;
DE   (YEPSE1_1.PE1).
GN   Name=ypkA; OrderedLocusNames=pYV0001;
OS   YERSINIA PSEUDOTUBERCULOSIS IP 32953.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Yersinia.
OX   NCBI_TaxID=273123;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS YEPSE1_1.PE1.
CC       Yersinia pseudotuberculosis IP 32953 plasmid pYV, complete sequence.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:YPKA_YERPS
CC   -!- FUNCTION: Acts as a virulence determinant.
CC   -!- CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr
CC       protein kinase family.
CC   -!- SIMILARITY: Contains 1 protein kinase domain.
CC   -!- GENE_FAMILY: HOG000219636 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q05608; Q663G6; -.
DR   EMBL; X69439; CAA49215.1; -; Genomic_DNA.
DR   EMBL; L33833; AAA68487.1; -; Genomic_DNA.
DR   EMBL; BX936399; CAF25344.1; -; Genomic_DNA.
DR   PIR; S30060; S30060.
DR   RefSeq; YP_068414.1; NC_006153.2.
DR   PDB; 2H7O; X-ray; 2.00 A; A=434-732.
DR   PDB; 2H7V; X-ray; 2.60 A; C/D=434-732.
DR   PDBsum; 2H7O; -.
DR   PDBsum; 2H7V; -.
DR   ProteinModelPortal; Q05608; -.
DR   SMR; Q05608; 439-732.
DR   PhosSite; Q05608; -.
DR   GeneID; 2952894; -.
DR   GenomeReviews; BX936399_GR; pYV0001.
DR   KEGG; yps:pYV0001; -.
DR   NMPDR; fig|273123.1.peg.1; -.
DR   OMA; VGELNIE; -.
DR   ProtClustDB; CLSK862113; -.
DR   BioCyc; YPSE273123:PYV0001-MON; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR000719; Prot_kinase_cat_dom.
DR   InterPro; IPR019093; Rac1-binding_domain.
DR   InterPro; IPR017442; Se/Thr_kinase-like_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   InterPro; IPR003547; Ser/thr_kinase_yersinia.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF09632; Rac1; 1.
DR   PRINTS; PR01373; YERSSTKINASE.
DR   SUPFAM; SSF56112; Kinase_like; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; FALSE_NEG.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
DR   HOGENOMDNA; YEPSE1_1.PE1; -.
KW   ypkA; putative targeted effector protein kinase;
KW   3D-structure; ATP-binding; Complete proteome; Kinase;
KW   Nucleotide-binding; Plasmid; Secreted;
KW   Serine/threonine-protein kinase; Signal; Transferase; Virulence.
SQ   SEQUENCE   732 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKSVKIMGTM PPSISLAKAH ERISQHWQNP VGELNIGGKR YRIIDNQVLR LNPHSGFSLF
     REGVGKIFSG KMFNFSIARN LTDTLHAAQK TTSQELRSDI PNALSNLFGA KPQTELPLGW
     KGEPLSGAPD LEGMRVAETD KFAEGESHIS IIETKDKQRL VAKIERSIAE GHLFAELEAY
     KHIYKTAGKH PNLANVHGMA VVPYGNRKEE ALLMDEVDGW RCSDTLRTLA DSWKQGKINS
     EAYWGTIKFI AHRLLDVTNH LAKAGVVHND IKPGNVVFDR ASGEPVVIDL GLHSRSGEQP
     KGFTESFKAP ELGVGNLGAS EKSDVFLVVS TLLHCIEGFE KNPEIKPNQG LRFITSEPAH
     VMDENGYPIH RPGIAGVETA YTRFITDILG VSADSRPDSN EARLHEFLSD GTIDEESAKQ
     ILKDTLTGEM SPLSTDVRRI TPKKLRELSD LLRTHLSSAA TKQLDMGGVL SDLDTMLVAL
     DKAEREGGVD KDQLKSFNSL ILKTYRVIED YVKGREGDTK NSSTEVSPYH RSNFMLSIVE
     PSLQRIQKHL DQTHSFSDIG SLVRAHKHLE TLLEVLVTLS QQGQPVSSET YGFLNRLAEA
     KITLSQQLNT LQQQQESAKA QLSILINRSG SWADVARQSL QRFDSTRPVV KFGTEQYTAI
     HRQMMAAHAA ITLQEVSEFT DDMRNFTVDS IPLLIQLGRS SLMDEHLVEQ REKLRELTTI
     AERLNRLERE WM
//

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