(data stored in ACNUC14238 zone)

HOGENOM: ZYGRO_1_PE113

ID   ZYGRO_1_PE113                        STANDARD;      PRT;   650 AA.
AC   ZYGRO_1_PE113; C5DPF1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Methylenetetrahydrofolate reductase; EC=1.5.1 20;
DE   (ZYGRO_1.PE113).
GN   OrderedLocusNames=ZYRO0A02838g;
OS   ZYGOSACCHAROMYCES ROUXII.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX   NCBI_TaxID=4956;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ZYGRO_1.PE113.
CC       Zygosaccharomyces rouxii strain CBS732 chromosome A complete sequence.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:C5DPF1_ZYGRC
CC   -!- CATALYTIC ACTIVITY: 5-methyltetrahydrofolate + NAD(P)(+) = 5,10-
CC       methylenetetrahydrofolate + NAD(P)H.
CC   -!- COFACTOR: FAD (By similarity).
CC   -!- PATHWAY: One-carbon metabolism; tetrahydrofolate pathway.
CC   -!- SIMILARITY: Belongs to the methylenetetrahydrofolate reductase
CC       family.
CC   -!- GENE_FAMILY: HOG000246234 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C5DPF1; -.
DR   EMBL; CU928173; CAR25562.1; -; Genomic_DNA.
DR   RefSeq; XP_002494495.1; XM_002494450.1.
DR   ProteinModelPortal; C5DPF1; -.
DR   STRING; C5DPF1; -.
DR   GeneID; 8201581; -.
DR   GenomeReviews; CU928173_GR; ZYRO0A02838g.
DR   KEGG; zro:ZYRO0A02838g; -.
DR   OrthoDB; EOG444PTG; -.
DR   GO; GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
DR   GO; GO:0006555; P:methionine metabolic process; IEA:InterPro.
DR   InterPro; IPR004621; Fadh2_euk.
DR   InterPro; IPR003171; Mehydrof_redctse.
DR   Pfam; PF02219; MTHFR; 1.
DR   TIGRFAMs; TIGR00677; Fadh2_euk; 1.
DR   HOGENOMDNA; ZYGRO_1.PE113; -.
KW   CAR25562.100026476820036002503210000011;
KW   ZYRO0A02838p;
KW   Complete proteome; FAD; Flavoprotein; Oxidoreductase.
SQ   SEQUENCE   650 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSIRELYESK DGPTLSLEFF PPKTETGKQN LLERMERMTA LGPLFATVTW GAGGSTAEKT
     LELASLAQKN LNLPICMHLT CTNMDRNIID DALTRCKAAG IHNILALRGD PPIGQDWSDL
     EASQSEFKHA VDLVRYINYR FPNEFCIGVA AYPEGHCEGE AEGNEQNPWK DLPFLKEKID
     AGADFVITQL FYDVDKFLQF EQMFRQHIST DLPLIPGLMP INSYLLFNRA AKLSHASIPS
     SVLQKFPPEI QADDDAVKSI GVDILIEIIE TIYKATHGRI KCFHFYTLNL EKAVAKIVAT
     SPTLSDTLDV VEDENDEAAT SEPEEQDQEG DIVLEDANVK NLIEDNRKRR RQSSTVSNVS
     SELTSNRVII GKKNQHGVGA PTRKVVISIS QGSGTLGRDA TWDEFPNGRF GDTRSPAFGE
     IDGYGPTLKV SNKKAYELWG QPKTIQDLQI IFIKYLEGSI DALPWCDLGL SPETALIQEE
     LIQLNERGFL TLASQPATNG SPSTNKIFGW GPAYGVVYQK AFIEMFVPKN IWENGNMKKA
     IEQYGRAKLT YYANDSQGNF ETNLESNSSN VVTWGVFSDS QVIQSTIVSE ESFKAWSDEA
     FSIWLEWAKL FPRNTSTNSL LRQIHQEYCL ISIVHHDYIN PDELWEIILS
//

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