ID   2243 PHOVERGEN49 34 seq.
AC   HBG002243
IO   0
KW   HBG002243//
LA   749
ND   34
CC   -!- TREE CALCULATED WITH PHYML
TR   ((((((((PYRG1_MOUSE:0.00000,(B1WC02_RAT:0.00354,B1AS53_MOUSE:0.00000)1:0.00000)1:0.00000,(Q3TPP2_MOUSE:0.01654,PYRG1_CRIGR:0.01799)1:0.00000)91:0.00487,A0JNE9_BOVIN:0.00863)77:0.00357,(((B4DR64_HUMAN:0.00000,B4E1E0_HUMAN:0.00000)1:0.00000,PYRG1_HUMAN:0.00000)1:0.00000,B4DMB5_HUMAN:0.02697)97:0.01173)70:0.00443,B7Z9C4_HUMAN:0.05333)95:0.03027,(PYG1B_XENLA:0.00759,PYG1A_XENLA:0.00469)100:0.07479)97:0.04560,(((Q6DBZ3_DANRE:0.01838,(B7ZVK1_DANRE:0.00350,A9JT21_DANRE:0.00000)58:0.00179)99:0.04966,Q4SYD8_TETNG:0.15684)52:0.01833,(((Q4THD8_TETNG:0.03650,Q4SGG9_TETNG:0.00000)96:0.06572,(PYRG1_DANRE:0.00000,A3QJW5_DANRE:0.00000)100:0.03717)64:0.00974,(B5X434_SALSA:0.04681,B5X4W4_SALSA:0.04042)88:0.01318)86:0.01306)94:0.03209):0.12809,(PYRG2_CHICK:0.05758,(((PYRG2_BOVIN:0.02889,(PYRG2_HUMAN:0.00000,B3KWM2_HUMAN:0.00000)97:0.02077)45:0.01824,(PYRG2_RAT:0.01364,((A2AEQ8_MOUSE:0.00000,(PYRG2_MOUSE:0.00000,A2AEQ7_MOUSE:0.00000)1:0.00000)1:0.00000,A2AEQ6_MOUSE:0.01277)93:0.01395)100:0.06396)100:0.10475,(PYRG2_XENLA:0.01933,B1H2S0_XENTR:0.00619)100:0.12722)1:0.01354):0.07187)100;
CC   -!- ALIGNMENT CALCULATED WITH MUSCLE
AL   B1H2S0_XENTR|B1H2S0_XENTR                                      1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGVGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQQVINRERRGDYLGKTVQVVPHITDAIQEWVLNQAKVPVDSDQKEPQICVIELGGTIGDIEGMPFIEAFRQFQFKAKRENFCNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSAKPIEMAVKQKISMFCHVEPEQVIFVHDVSSTYRVPILLQEQGIIKYFKQRLSIPIDDQPSTLLFKWKRMADRYERLLKTCSIALVGKYTKLSDCYTSVFKALEHSALAINHKLNLMYIDSADLEPSMKAEDPVKYHKAWEELCKAEGILVPGGFGLRGTEGKIQAITWARERKIPFL----------------------GICLGMQLAVVEFARNILKMT----------------------------DANSTEFDPNTNNPVVIDMPEHHPGDMGGTMRLGRRKTVFKTSDSVIKKLYDNYEFVEERHRHRYEVNPELVHQFEEKGLKFVGQDNEGQRMEIIELEGHPYFVGVQFHPEFCSRPMKPSPPYLGFMLAASGKFNSYVQNGCKLSPRNSY-SEHSDESSSDS-------------
AL   PYRG2_XENLA|PYRG2_XENLA                                        1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGVGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQQVINRERRGDYLGKTVQVVPHITDAIQEWVLNQAKVPVDRDQKEPQICVIELGGTIGDIEGMPFIEAFRQFQFKAKRENFCNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSAKPIEMAVKQKISMFCHVEPEQVIFVHDVSSTYRVPILLQEQGIIKYFKQRLSIPIEDQPSTQLFKWKRMADRYERLLKTCSIALVGKYTKLSDCYTSVFKALEHSALAINHKLNLMYIDSADLEPSMKAQDPVKYHKAWEELCKAEGILVPGGFGLRGTEGKIQAITWARERKIPFL----------------------GICLGMQLAVVEFARNILKMT----------------------------DANSTEFDPNTKNPAVIDMPEHHPGDMGGTMRLGSRKTVFKTSESVVKKLYDNQDFVEERHRHRYEVNPELVQQFEEKGLKFVGQDNEGQRMEIIELEGHPYFVGVQFHPEFCSRPMKPSPPYLGFMLAASGKLNTYVQNGCKLSPRNSY-SEHSDESSSDS-------------
AL   PYRG2_RAT|PYRG2_RAT                                            1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAIQDWVMNQAKVSVDGNKEDPQICVIELGGTIGDIEGMAFVEAFRQFQFKAKRENFYNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSIYRVPLLLEEQGVVKYFQERLDLPINDCSNNLLFKWKTMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEPVTKAEDPVKFHEAWQKLCLADGILVPGGFGIRGTLGKLQAISWARTKKIPFL----------------------GICLGMQLAVIEFARNCLNLK----------------------------DANSTEFDPNTPVPLVIDMPEHNPGDLGGTMRLGLRRTVFTTENSILKKLYGDVPYIEERHRHRYEVNPNLINQFENKDLCFVGEDVDGKRMEIIELTGHPYFIGVQFHPEFSSRPMKPSPPYLGLLLAATGTLNTHLQQMSKLSYSDIY-SDASDDSFSEAKFAELDIN-----
AL   A2AEQ7_MOUSE|A2AEQ7_MOUSE                                      1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAIQEWVMNQAKVSVDGNKEDPQICVIELGGTIGDIEGMAFVEAFRQFQFKAKKENFYNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSIYRVPLLLEEQGVVKYFQERLGLPINDCSSNLLFKWKAMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEPVTKAEDPVKFHEAWQKLCLADGILVPGGFGIRGTLGKLQAISWARTKKIPFL----------------------GICLGMQLAVIEFARNCLNLK----------------------------DANSTEFEPNTPVPLVIDMPEHNPGDLGGTMRLGLRRTVFTTENSILKKLYGDVPYIEERHRHRYEVNPNLINQFENKDLCFVGEDVDGKRMEIVELTSHPYFIGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAHLQQMNKLPYSDGY-SDASDDSFPEAKLAELDLN-----
AL   PYRG2_MOUSE|PYRG2_MOUSE                                        1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAIQEWVMNQAKVSVDGNKEDPQICVIELGGTIGDIEGMAFVEAFRQFQFKAKKENFYNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSIYRVPLLLEEQGVVKYFQERLGLPINDCSSNLLFKWKAMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEPVTKAEDPVKFHEAWQKLCLADGILVPGGFGIRGTLGKLQAISWARTKKIPFL----------------------GICLGMQLAVIEFARNCLNLK----------------------------DANSTEFEPNTPVPLVIDMPEHNPGDLGGTMRLGLRRTVFTTENSILKKLYGDVPYIEERHRHRYEVNPNLINQFENKDLCFVGEDVDGKRMEIVELTSHPYFIGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAHLQQMNKLPYSDGY-SDASDDSFPEAKLAELDLN-----
AL   A2AEQ8_MOUSE|A2AEQ8_MOUSE                                      1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAIQEWVMNQAKVSVDGNKEDPQICVIELGGTIGDIEGMAFVEAFRQFQFKAKKENFYNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSIYRVPLLLEEQGVVKYFQERLGLPINDCSSNLLFKWKAMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEPVTKAEDPVKFHEAWQKLCLADGILVPGGFGIRGTLGKLQAISWARTKKIPFL----------------------GICLGMQLAVIEFARNCLNLK----------------------------DANSTEFEPNTPVPLVIDMPEHNPGDLGGTMRLGLRRTVFTTENSIL---------------------------------------------------SHPYFIGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAHLQQMNKLPYSDGY-SDASDDSFPEAKLAELDLN-----
AL   A2AEQ6_MOUSE|A2AEQ6_MOUSE                                      1   749 1.00  -------------------------------MGSELLGKNSALFSSFPTFCGGGPLGCTVADGQTFMIASGYWQSPIRPPMKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAIQEWVMNQAKVSVDGNKEDPQICVIELGGTIGDIEGMAFVEAFRQFQFKAKKENFYNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSIYRVPLLLEEQGVVKYFQERLGLPINDCSSNLLFKWKAMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEPVTKAEDPVKFHEAWQKLCLADGILVPGGFGIRGTLGKLQAISWARTKKIPFL----------------------GICLGMQLAVIEFARNCLNLK----------------------------DANSTEFEPNTPVPLVIDMPEHNPGDLGGTMRLGLRRTVFTTENSIL-----------------------------------------------------------------------------SLYLQCSG-------------------------------------------
AL   B3KWM2_HUMAN|B3KWM2_HUMAN                                      1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQAKVPVDGNKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQLSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSTYRVPVLLEEQSIVKYFKERLHLPIGDSASNLLFKWRNMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEKITETEDPVKFHEAWQKLCKADGILVPGGFGIRGTLGKLQAISWARTKKIPFL----------------------GVCLGMQLAVIEFARNCLNLK----------------------------DADSTEFRPNAPVPLVIDMPEHNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRHRFEVNPNLIKQFEQNDLSFVGQDVDGDRMEIIELANHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAYLQQGCKLSSSDRY-SDASDDSFSEPRIAELEIS-----
AL   PYRG2_HUMAN|PYRG2_HUMAN                                        1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQAKVPVDGNKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQLSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSTYRVPVLLEEQSIVKYFKERLHLPIGDSASNLLFKWRNMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEKITETEDPVKFHEAWQKLCKADGILVPGGFGIRGTLGKLQAISWARTKKIPFL----------------------GVCLGMQLAVIEFARNCLNLK----------------------------DADSTEFRPNAPVPLVIDMPEHNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRHRFEVNPNLIKQFEQNDLSFVGQDVDGDRMEIIELANHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAYLQQGCKLSSSDRY-SDASDDSFSEPRIAELEIS-----
AL   PYRG2_BOVIN|PYRG2_BOVIN                                        1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQAMVPVDGHKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSTYRVPVLLEEQGIIKYFKERLDLPIGDSASSLLSKWRNMADRYERLQKTCSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEQTTEVEDPVKFHEAWQKLCKADGVLVPGGFGIRGTLGKLQAISWARSRKIPFL----------------------GVCLGMQLAVIEFARNCLNLK----------------------------DADSTEFEPNARVPVVIDMPEHNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRHRYEVNPSLISQLEQKDLSFVGQDVDGERMEIIELANHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAYLLQGCKLSSSDRY-SDASDDSFSEPRLAELEIS-----
AL   PYRG2_CHICK|PYRG2_CHICK                                        1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERHGDYLGKTVQVVPHITDAVQEWVMNQAKVPVDDDRKEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQPNATGEQKTKPTQNSVRALRGLGLSPDLIVCRSAKPIEMAVKEKISMFCHVEPEQVIFIHDVSSTYRVPILLEEQGIIKYFKQRLNLPIDDQPSDLLMKWKKMADRYERLLKVCSIALVGKYTKLSDCYASVFKALEHSALAINHKLDLMYIDSTELERSTEVENSVKYHQAWHKLCKADGILVPGGFGIRGTEGKLQAISWARTKKKPFL----------------------GVCLGMQLAVVEFARNCLNWK----------------------------DANSTEFDPDTKSPVVIDMPEHNPGDMGGTMRLGKRRTVFKTQNSILRKLYGDEMFVEERHRHRYEVNPELTHCFEEKGLKFVGHDTEGNRMEMIELENHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGTLNAYLQRGCKLSPSESY-SDLSDDSSPEKEFPKSETS-----
AL   Q4SYD8_TETNG|Q4SYD8_TETNG                                      1   749 1.00  PNTVRTLERDRPANPQQPNSRGSQISLVLVTMNSSEGELNKLVKDGAIRIGKIQPGYGQIFFSFTSFPDELCHHSYSHVAMKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTKNNNLTTGKIYQSVINKERKGDYLGKTVQVVPHITDAIQEWVMKQARVSVDDDDIEPEVCVIE----------------------------------------------------------------------------------------------VICVQDVSSIYRVPLLLEEQGVVNYFCNRLNMSVKMSPRKMLTKWKEMADRSDRLLEHVTIALVGKYTKLADSYTSVIKALEHSALAINHKLEVKYIDSEDLEPTTLGVEPVKYHEAWQKLCSSQGVLVPGGFGARGTEGKMLAINWARKQNKPYL----------------------GVCLGMQLAVCEFARNVLGWK----------------------------DANSTEFNPESKYPVVIEMPEHNPGQMGGTMRLGKRRTVFKSDTSVMKKLYGNVDFIDERHRHRFEVNPALKDYFVKHGLQFVGQDVQGERMEIVELEDHCYFVGVQYHPEFTSRPIKPSPPYFGLLLAAAGKLQSYLSKGCQLSPRDMYCCSSSGSSSPEPDITELKF------
AL   PYG1A_XENLA|PYG1A_XENLA                                        1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGVIASSIGTILKSSNLHVTSIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQSVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGIEPEVCVIELGGTVGDIESMPFVEAFRQFQFKVRRENFCNIHVSLVPQPSATGEQKTKPTQNSVRELRGLGLSPDLVVCRCSTPLDTSVKEKISMFCHVEPQQVICVHDVSSIYRVPLLLEEQGVVDYFRQRLDLPIGRQPRRLLMKWKEMADRYERLLESCSIALVGKYTKFSDSYASVIKALEHSALAINHRLEIKYIDSADLEQETLQEEPVRYHEAWQKLCSSEGILVPGGFGVRGTEGKIQAIAWARKQKKPFL----------------------GVCLGMQLAVVEFARDVLGWT----------------------------DANSTEFNPKTSHPVVIDMPEHNPGQMGGTMRLGKRRTIFHSQNSIMKKLYGGHEYVEERHRHRYEVNPELRRELEVRGLKFVGQDTEGERMEIVELEDHPYFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSQYIERGCRLSPRDTY-SDRSENSSPDAEIAELKLPMIDHD
AL   PYG1B_XENLA|PYG1B_XENLA                                        1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGVIASSVGTILKSSNLHVTSIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQSVINKERKGDYLGKTVQVVPHITEAIQEWVMRQALIPVDEDGIEPEVCVIELGGTVGDIESMPFVEAFRQFQFKARRENFCNIHVSLVPQPSATGEQKTKPTQNSVRELRGLGLSPDLVVCRCSTPLDTSVKEKISMFCHVEPQQVICVHDVSSIYRVPLLLEEQGVVDYFRQRLDLPIGRQPRRLLMKWKEMADRYERLLESCSIALVGKYTKFSDSYASVIKALEHSALAINHRLEIKYIDSADLEQETLQEEPVRYHEAWQKLCSSDGILVPGGFGVRGTEGKIQAIAWARKQKKPFL----------------------GVCLGMQLAVVEFARDVLDWK----------------------------DANSTEFNPKTSHPVVIDMPEHNPGQMGGTMRLGKRRTIFHSQNSVMKKLYGGHEYVEERHRHRYEVNPELRRELEARGLKFVGQDTEGERMEIVELEDHPYFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSQYIERGCRLSPRDTY-SDRSENSSPDAEIAELKLPMIDHE
AL   B4E1E0_HUMAN|B4E1E0_HUMAN                                      1   749 1.00  -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFL----------------------GVCLGMQLAVVEFSRNVLGWQ----------------------------DANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGCRLSPRDTY-SDRSGSSSPDSEITELKFPSINHD
AL   PYRG1_HUMAN|PYRG1_HUMAN                                        1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFL----------------------GVCLGMQLAVVEFSRNVLGWQ----------------------------DANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGCRLSPRDTY-SDRSGSSSPDSEITELKFPSINHD
AL   B4DR64_HUMAN|B4DR64_HUMAN                                      1   749 1.00  --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFL----------------------GVCLGMQLAVVEFSRNVLGWQ----------------------------DANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGCRLSPRDTY-SDRSGSSSPDSEITELKFPSINHD
AL   B4DMB5_HUMAN|B4DMB5_HUMAN                                      1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQAVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFL----------------------GVCLGMQLAVVEFSRNVLGWQ----------------------------DANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVRI-------------------------------------------------PACWYSGKIVS----------------------------------------------
AL   B7Z9C4_HUMAN|B7Z9C4_HUMAN                                      1   749 1.00  -------------------------------------------------------------------------MPKSKSKMKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRFA--------------------------------------------------------------------CNEE------------------------------L----------------------GVLASFTLL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
AL   PYRG1_CRIGR|PYRG1_CRIGR                                        1   749 1.00  -----------------------------------------------------------------------------------------------------------------------DPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVHVVPHITDAIQRWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRSLELPIERQSRKMLMKWKEMADRYDRLLETCSIALVGKYTKLSDSYASVIKALEHSALAINHKLEIKYIDSTDLEPSTLQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARKQKKPFL----------------------GVCLGMQLAVVEFSRNVLGWQ----------------------------DANSTEFDPKTSHPVVIDMPEHNPGQMGGTMRLGKSRTLFQTKNSVMSKLYGDTDYLEERHRHRFEVNP----------------------------------------------------------------------------------------------------------
AL   A0JNE9_BOVIN|A0JNE9_BOVIN                                      1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSTDLEPSTLQEDPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAISWARKQKKPFL----------------------GVCLGMQLAVVEFSRNVLGWQ----------------------------DANSTEFDPNTNHPVVIDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDPDYLEERHRHRFEVNPVLKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLPHYLQKGCRLSPRDTY-SDRSGSSSPDSEITELKFPSINHD
AL   Q3TPP2_MOUSE|Q3TPP2_MOUSE                                      1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGVIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLEVCRCSNPLDTSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
AL   B1AS53_MOUSE|B1AS53_MOUSE                                      1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGVIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQSRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSTDLEPSTLQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARKQKKPFL----------------------GVCLGMQLAVVEFSRNVLGWQ----------------------------DANSTEFDPKTSHPVVIDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDTDYLEERHRHRFEVNPVLKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLPHYLQKGCRLSPRDTY-SDRSGSSSPDSEITELKFPSISQD
AL   PYRG1_MOUSE|PYRG1_MOUSE                                        1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGVIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQSRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSTDLEPSTLQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARKQKKPFL----------------------GVCLGMQLAVVEFSRNVLGWQ----------------------------DANSTEFDPKTSHPVVIDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDTDYLEERHRHRFEVNPVLKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLPHYLQKGCRLSPRDTY-SDRSGSSSPDSEITELKFPSISQD
AL   B1WC02_RAT|B1WC02_RAT                                          1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGVIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKKENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPVERQSRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSTDLEPSTLQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARKQKKPFL----------------------GVCLGMQLAVVEFSRNVLGWQ----------------------------DANSTEFDPKTSHPVVIDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDTDYLEERHRHRFEVNPVLKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLPHYLQKGCRLSPRDTY-SDRSGSSSPDSEITELKFPSISQD
AL   A3QJW5_DANRE|A3QJW5_DANRE                                      1   749 1.00  ----------------------------------------------------------------------------MISKMKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQSVINKERRGDYLGKTVQVVPHITDAIQEWVMRQAKIPVDDDDVEPQVCVIELGGTVGDIESMPFVEAFRQFQFKVKRENFCNIHVSLVPQPSATGEQKTKPTQNSVRELRGLGLSPDLIMCRCSTPLDNSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEDQGVVGYFCRRLNLPIENRPRKMLAKWKEMSDRSDRLLEQCSIALVGKYTKFSDSYASVIKALEHSALAISHKLEVKYVDSADLEPSMLQEEPVKYHEAWQKLCSSDGILVPGGFGVRGTEGKIQAINWARKQKKPFL----------------------GVCLGMQLAVCEFARNMLDWT----------------------------DANSTEFDPETKHPVVIDMPEHNPGQMGGTMRLGKRRTIFKNKSSILRKLYGDVDYVEERHRHRFEVNPELKHHFEEKGFRFVGQDVEGERMEVIEMDDHPYFVGVQYHPEFTSRPIKPSPPYLGLLLAAAGRLQSYLQKGCRLSPRDAY-SDRSGSSSPDLEIADLKLRSIAQE
AL   PYRG1_DANRE|PYRG1_DANRE                                        1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQSVINKERRGDYLGKTVQVVPHITDAIQEWVMRQAKIPVDDDDVEPQVCVIELGGTVGDIESMPFVEAFRQFQFKVKRENFCNIHVSLVPQPSATGEQKTKPTQNSVRELRGLGLSPDLIMCRCSTPLDNSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEDQGVVGYFCRRLNLPIENRPRKMLAKWKEMSDRSDRLLEQCSIALVGKYTKFSDSYASVIKALEHSALAISHKLEVKYVDSADLEPSMLQEEPVKYHEAWQKLCSSDGILVPGGFGVRGTEGKIQAINWARKQKKPFL----------------------GVCLGMQLAVCEFARNMLDWT----------------------------DANSTEFDPETKHPVVIDMPEHNPGQMGGTMRLGKRRTIFKNKSSILRKLYGDVDYVEERHRHRFEVNPELKHHFEEKGFRFVGQDVEGERMEVIEMDDHPYFVGVQYHPEFTSRPIKPSPPYLGLLLAAAGRLQSYLQKGCRLSPRDAY-SDRSGSSSPDLEIADLKLRSIAQE
AL   A9JT21_DANRE|A9JT21_DANRE                                      1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTRDNNLTTGKIYQSVINKERRGDYLGKTVQVVPHITDAIQEWVMRQAKVSVDDDGIEPEVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPNSTGEQKTKPTQNSVRELRGLGLSPDLIVCRCSTPLDTAVKEKISMFCHVEPEQVICIHDVSSIYRVPLLLEDQGMVHYFCRRLDLPIQMRPRQMLRKWKEMSDRSDRLLEQTSIALVGKYTKLSDSYASVIKALEHSALAINYKLEVKYIDSAYLEPAALQDEPVKYHEAWQKLCSADGVLVPGGFGVRGTEGKIQAINWARKQKKPFL----------------------GVCLGMQLAVCEFARNVLGWE----------------------------DANSTEFDPETKHPVVIEMPEHNPGQMGGTMRLGKRRTLFKSTPSILRKLYGDAEYVDERHRHRFEVNPELKHHFEDRGFRFVGQDLEGERMEIIELEDHTYFVGVQYHPEFTSRPIKPSPPYFGLLLAASGKLQNYLQKGCRLSPRDAY-SDRSGTSSPDSEISEFKFPSLS--
AL   B7ZVK1_DANRE|B7ZVK1_DANRE                                      1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTRDNNLTTGKIYQSVINKERRGDYLGKTVQVVPHITDAIQEWVMRQAKVSVDDDGIEPEVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPNSTGEQKTKPTQNSVRELRGLGLSPDLIVCRCSTPLDTAVKEKISMFCHVEPEQVICIHDVSSIYRVPLLLEDQGMVHYFCRRLDLPIQMRPRQMLRKWKEMSDRSDRLLEQTSIALVGKYTKLSDSYASVIKALEHSALAINYKLEVKYIDSAYLEPAALQDEPVKYHEAWQKLCSADGVLVPGGFGVRGTEGKIQAINWARKQKKPFL----------------------GVCLGMQLAVCEFARNVLGWE----------------------------DANSTEFDPETKHPVVIEMPEHNPGQMGGTMRLGKRRTLLKSTPSILRKLYGDAEYVDERHRHRFEVNPELKHHFEDRGFRFVGQDLEGERMEIIELEDHTYFVGVQYHPEFTSRPIKPSPPYFGLLLAASGKLHNYLQKGCRLSPRDAY-SDRSGTSSPDSEISEFKFPSLS--
AL   Q6DBZ3_DANRE|Q6DBZ3_DANRE                                      1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTRDNNLTTGKIYQSVINKERRGDYLGKTVQVVPHITDAIQEWVMRQAKVSVDDDGIEPEVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPNSTGEQKTKPTQNSVRELRGLGLSPDLIVCRCSTPLDTAVKEKISMFCHVEPEQVICIHDVSSIYRVPLLLEDQGMVHYFCRRLDLPIQMRPRQMLRKWKEMSDRSDRLLEQTSIALVGKYTKLSDSYASVIKALEHSALAINYKLEVKYIDSAYLEPAALQDEPVKYHEAWQKLCSADGVLVPGGFGVRGTEGKIQAINWARKQKKPFL----------------------GVCLGMQLAVCEFARNVLGWE----------------------------DANSTEFDPETKHPVV--------------------------------------------------------------GVRLVKQII-------------------------------------------------------------IY-T-----------------------
AL   B5X4W4_SALSA|B5X4W4_SALSA                                      1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSVGTILKSCGLRVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQSVINKERKGDYLGKTVQVVPHITDAIQEWVMRQARVPVDDDGVEPQICVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSATGEQKTKPTQNSVRELRGLGLSPDLIMCRCSTPLENSVKEKISMFCHVEPEQVICVADVSSIYRVPLLLENQGVVGYFCQRLDLPIETRPRKMLTKWKEMSDRSDRLLEQCSIALVGKYTKFTDSYASVIKALEHSALAICHKLDIKYIDSADLEPNTLKEEPVKYHEAWQKLCSADGILVPGGFGVRGTEGKIHAINWARKQKKPFL----------------------GVCLGMQLAVCEFARNVLEWE----------------------------DANSTEFHPESKHPVVIDMPEHNPGQMGGTMRLGKRRTIFKTTNSILRRLYGDAEYVDERHRHRFEVNPELKDHFEGKGFHFVGQDVEGERMEVIELDDHPYFVGVQYHPEFTSRPIKPSPPYFGLLLASAGKLQSYLQKGCRLSPRDTY-SDQSGSSTPDSEIAESISQEFV--
AL   B5X434_SALSA|B5X434_SALSA                                      1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSVGLILKSCGLHVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTRDNNLTTGKIYQSVINKERRGDYLGKTVQVVPHITDAIQEWVVKQAKISVDDDGVEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRDNFCNIHVSLVPQPSATGEQKTKPTQNSVRELRGLGLSPDLIMCRCATPLENAVKEKISMFCHVEPTQVICVADVSSIYRVPLLLEDQGVVGYICQRLDLPIEMRARKMLTKWKEMSDRSDRLLEHVSVALVGKYTKFSDSYASVIKALEHSALAINHKLEIKFIDSADLEPNTLQEEPVKYHEAWQKLCSADGVLVPGGFGVRGTEGKIQAISWARKKKKPFL----------------------GICLGMQLAVCEFARNVLGWQ----------------------------DANSTEFHPESKHPVVIDMPEHNPGQMGGTMRLGKRRTIFKSNTSILRKLYGDAEYVDERHRHRFEVNPELKHHFEERGFHFVGQDIEGERMEVIELDDHAYFVGVQYHPEFTSRPIKPSPPYFGLLLAAAGKLQSYLQKGCRLSPRDTY-SDRSDSSSPDSEIAELKF------
AL   Q4SGG9_TETNG|Q4SGG9_TETNG                                      1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTAIKIDPYINIDAGTFSPYEHGRSEGVDEPVCVCVCVCVCVMVASCHAGEVFVLDDGGEVDLDLGNYERFLDIRLTRDNNLTTGKIYQSVINKERRGDYLGKTVQVVPHITDAIQEWVEKQATVPVDDDGVEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVRRENFCNIHVSLIPQPGTTGEQKTKPTQNSVRELRGLGLSPDLIMCRCTTALENSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLESQGVVSYLSRRLNMPIETRPRKMLTKWKEMSDRSDRLLEQCSIALVGKYTKFSDSYASVIKALEHSALAISHKLEVKYIDSACLEPSTLQEEPVKYHEAWQKLCSSDGVLVPGGFGVRGTEGKIHAIGWARKQRKPFLGENVRLSEGVAPVTVSKTFVCAGVCLGMQLAVCEFARNELGWEGDHHTTVYWFFQISRRTFLTCISFFFGSDANSTEFDPESKHPVVIDMPEHNPGQMGGTMRLGKRRTIFRAPGSILRKLYGDAEYVEERHRHRFEVNPELKSHFEDKGFRFVGQDIEGERMEVIELDEHPYFVGVQYHPEFTSRPIKPSPPYLGLLLASAGKLQSYLQKGCRLSPRDTY-SDHSGSSTPDSEISELKLPSISSE
AL   Q4THD8_TETNG|Q4THD8_TETNG                                      1   749 1.00  --------------------------------------------------------------------------------MKYILVTGGVISGIGKGIIASSVGTILKVCGLHVTAIKIDPYINIDAGTFSPYEH---------------------------GEVFVLDDGGEVDLDLGNYERFLDIRLTRDNNLTTGKIYQSVINKERRGDYLGKTVQVVPHMTDAIQEWVEKQVTVPVDDDGVEPQVCVIELGGTVGDIESMPFI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
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