Alignment of the gene Family HOG000039981 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL194603_1_PE1 NOISO VIMSELSAAPAGSSQGQQKPLRVGFYDVERTLGKGNFAVVKLARHRVTKTQ--------- ANOCA118_1_PE4 NOISO VIMSDYTPVPT-SNQSQQRPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQ--------- BOVIN1_151_PE19 NOISO VIMSELSAAPAGSGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQ--------- CALJA21_49_PE3 NOISO VIMSEFSADPAGQ--GQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQ--------- CANFA31_40_PE24 NOISO VIMSE----------LQQKPLRVGFYDVERTLGKGNFAVVKLARHRVTKTQ--------- CAOWC1_1_8257 NOISO ------MATTRGAYRGRLRMIKLGDYQLLQTIGTGAFSKVKQAVHLPSEVD--------- CAVPO90_4_PE5 NOISO VIMSEL---------SQQKTLRVGFYDVERTLGKGNFAVVKLARHRVTKTQ--------- CHICK1_PE1912 NOISO VIMSEYASVPA-PSAAQPRPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQ--------- DANRE9_10_PE10 ISOFORMIN -------------------PLQVGFYEIIRTLGKGNFAVVKLARHKVTKTQ--------- DANRE9_10_PE9 ENSDARG00000058606 VIMTDSRTGSH-SSCAQARPLQVGFYEIIRTLGKGNFAVVKLARHKVTKTQAITTFYFIF DIPOR24691_PE1 NOISO ------------------------------------------------------------ FELCAGS_3190_PE2 NOISO VIMSELSAAPAGSGQSQQKPLRVGFYDVERTLGKGNFAVVKLARHRVTKTQ--------- FUGRU42_1_PE71 NOISO VIMSESSQAAQ-SRPGLGRPLQVGFYEIIRTLGKGNFAVVKLARHKVTKTQ--------- GASACGROUPXVI_8_PE88 NOISO VIMTENSRGAQ-SSAAQGRPLQVGFYEIIRTLGKGNFAVVKLAKHKVTKTQ--------- GORGO21_33_PE9 NOISO VIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQ--------- HORSE26_39_PE13 NOISO VIMSEFSAAPAGSGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQ--------- HS21_PE783 NOISO VIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQ--------- LOXAF67_11_PE8 NOISO VIMSEFSTAAVGSGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQ--------- MACEUGS_5215_PE1 NOISO VIMSEFTSVPT-SSQTQQRPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQ--------- MACMU3_4_PE8 NOISO ------------------------------------------------------------ MICMU10143_PE1 NOISO VIMSEFGAAPA----GQQKPLRVGFYDVERTLGKGNFAVVKLARHRVTKTQ--------- MONDO4_10_PE20 NOISO VIMSEFTSVPI-SNQTQQRPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQ--------- MOUSE17_PE914 NOISO VIMSEFSAVPSGTGQGQQKPLRVGFYDVERTLGKGNFAVVKLARHRVTKTQ--------- MYOLUGS_2972_PE1 NOISO ------------------------------------------------------------ NEMVE_5053_PE7 NOISO --------------MDRSKAIRVGFYEIDKTIGKGNFSVVKLARHRITKSQ--------- OCHPR24279_PE1 NOISO ------------------------------------------------------------ ORNANULTRA222_5_PE7 ENSOANG00000006466 VIMSDFTSVPI-SSHIQQRPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQ--------- ORNANULTRA222_5_PE8 ISOFORMIN VIMSDFTSVPI-SSHIQQRPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQ--------- ORYLA21_6_PE2 NOISO VIMTETSGGSQ-PSPAQRRPLQVGFYEIIRTLGKGNFAVVKLAKHKVTKTQ--------- OTOGA106538_PE1 NOISO ------------------------------------------------------------ PANTR21_44_PE11 NOISO VIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQ--------- POEGU1_5_PE12 NOISO VIMSEFASAPA-AAHGQQRPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQ--------- POEGUUN_26_PE2 NOISO --------------------------------------------------Q--------- PONPY21_46_PE1 NOISO VIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQ--------- PROCAGS_3809_PE1 NOISO VIMSEFSAAASGSGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTR--------- PTEVA15161_PE1 NOISO ------------------------------------------------------------ RAT20_PE448 NOISO VIMSEFSAVPTGTGQGQQKPLRVGFYDVERTLGKGNFAVVKLARHRVTKTQ--------- SPETRGS_2922_PE1 NOISO VIMSEFSAAPAGADQGQQKPLRVGFYDVERTLGKGNFAVVKLA-HRVTKTQ--------- TETNG2_PE879 NOISO VIMS---EAAP-CRAGPGRPLQVGFYEILRTLGKGNFAVVKLARHKVTKTQ--------- TURTR106893_PE1 NOISO ------------------------------------------------------------ XENTR1084_PE7 ISOFORMIN GIMRESC----GAGGPPNRPLRVGFYDIKETLGKGNFAVVKLAQHRVTNTQGA------- XENTR1084_PE8 ENSXETG00000013685 GIMRESC----GAGGPPNRPLRVGFYDIKETLGKGNFAVVKLAQHRVTNTQGA------- XENTR1084_PE9 ISOFORMIN GIMRESC----GAGGPPNRPLRVGFYDIKETLGKGNFAVVKLAQHRVTNTQGA------- MATCH CONSENSUS ???????????????????????G?Y????T?G?G?F??VK?A?H???????????????

AILMEGL194603_1_PE1 NOISO --VAIKIIDKTRLDSSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE ANOCA118_1_PE4 NOISO --VAIKIIDKTRLDPSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE BOVIN1_151_PE19 NOISO --VAIKIIDKARLDSSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE CALJA21_49_PE3 NOISO --VAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE CANFA31_40_PE24 NOISO --VAIKIIDKTRLDSSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE CAOWC1_1_8257 NOISO --VAMKIISKKKIDSSSMDKLRREMHIIRELRHPNIIRLFHVMETEEELILVTEFAKNGE CAVPO90_4_PE5 NOISO --VAIKIIDKTRLDPSNLEKIYREVQLMKLLNHPHIIRLYQVMETKDMLYIVTEFAKNGE CHICK1_PE1912 NOISO --VAIKIIDKTRLDPSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE DANRE9_10_PE10 ISOFORMIN --VAIKIIDKTRLNSANLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEYAKNGE DANRE9_10_PE9 ENSDARG00000058606 MQVAIKIIDKTRLNSANLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEYAKNGE DIPOR24691_PE1 NOISO --VAIKIIDKTRLDSGNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE FELCAGS_3190_PE2 NOISO --VAIKIIDKTRLDSSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE FUGRU42_1_PE71 NOISO --VAIKIIDKTRLNPSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEYAKNGE GASACGROUPXVI_8_PE88 NOISO --VAIKIIDKTRLNPSNLEKIYREVQIMKLLNHPHIIKLYQVMETTDMLYIVTEYAKNGE GORGO21_33_PE9 NOISO --VAIKIIDKTRLDASNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE HORSE26_39_PE13 NOISO --VAIKIIDKTRLDSSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE HS21_PE783 NOISO --VAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE LOXAF67_11_PE8 NOISO --VAIKIIDKTRLDPSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE MACEUGS_5215_PE1 NOISO --VAIKIIDKARLDSSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE MACMU3_4_PE8 NOISO ---------------------------MKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE MICMU10143_PE1 NOISO --VAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE MONDO4_10_PE20 NOISO --VAIKIIDKARLDPSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE MOUSE17_PE914 NOISO --VAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPNIIKLYQVMETKDMLYIVTEFAKNGE MYOLUGS_2972_PE1 NOISO --VAIKIIDKTRLDSSNLEKIYREVQIMKLLNHPHIIKLYQXXXXXXXXXXXXXXXXXXX NEMVE_5053_PE7 NOISO --VAIKIIDKTQLNEMNLKKIYREVQIMKLLQHPHIVKLYQVMETKNMLYLVTDYANNGE OCHPR24279_PE1 NOISO ------------------------------------------------------------ ORNANULTRA222_5_PE7 ENSOANG00000006466 --VAIKIIDKTRLDSSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE ORNANULTRA222_5_PE8 ISOFORMIN --VAIKIIDKTRLDSSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE ORYLA21_6_PE2 NOISO --VAIKIIDKTRLSPSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEYAKNGE OTOGA106538_PE1 NOISO --VAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE PANTR21_44_PE11 NOISO --VAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE POEGU1_5_PE12 NOISO --VAIKIIDKTRLDPSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE POEGUUN_26_PE2 NOISO --VAIKIIDKTRLDPSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE PONPY21_46_PE1 NOISO --VAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGE PROCAGS_3809_PE1 NOISO --VAIKIIDKTR-DPSNLEKIYREVXXXXXXXXXXXXXXXXVMETKDMLYIVTEFAKNGE PTEVA15161_PE1 NOISO -----------------------------------------VMETKDMLVTEI-----KN RAT20_PE448 NOISO --VAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPNIIKLYQVMETKDMLYIVTEFAKNGE SPETRGS_2922_PE1 NOISO --VAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIKLYQXXXXXXXXXXXXXXXXXXX TETNG2_PE879 NOISO --VAIKIIDKTRLSPSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEYAKNGE TURTR106893_PE1 NOISO --VAIKIIDKTRLDSSNLEKIYREVQIMKLLSHPHIIKLYQVMETKDMLYIVTEFAKNGE XENTR1084_PE7 ISOFORMIN ----VSVWGGTWGSISRGVHGAVSVRYNTNWG-----FSVQVMETKDMIYIVTEYAKNGE XENTR1084_PE8 ENSXETG00000013685 ----VSVWGGTWGSISRGVHGAVSVRWGGSLTRGGSLTGVQVMETKDMIYIVTEYAKNGE XENTR1084_PE9 ISOFORMIN ----VSVWGGTWGSISRGVHGAVSVRYNTNWG-----FSVQVMETKDMIYIVTEYAKNGE MATCH CONSENSUS ??VAIKIIDKTRL??SNLEKIYREVQ?MKLL?HP?IIKLYQVMETKDMLYIVTE?AKNGE

AILMEGL194603_1_PE1 NOISO MFDYLTSNGHLSENEAREKFWQILSAVEYCHSRHIVHRDLKTENLLLDGSMDIKLA---- ANOCA118_1_PE4 NOISO MFDHLTSHGHLSESEARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDANMNIKLA---- BOVIN1_151_PE19 NOISO MFDYLTSNGHLSESEARKKFWQILSAVEYCHSHNIVHRDLKTENLLLDDNMDIKLA---- CALJA21_49_PE3 NOISO MFDYLTSNGHLSESEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLA---- CANFA31_40_PE24 NOISO MFDYLTSNGHLSENEARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDGSMDIKLA---- CAOWC1_1_8257 NOISO IYDHIVETGKLTETAARKKFTQLASAVEYCHGQGIVHRDLKVENMLLDDDFNVKLV---- CAVPO90_4_PE5 NOISO MFDYLTANGHLSEKEARRKFWQILSAVEYCHNHHIVHRDLKTENLLLDANMDVKLA---- CHICK1_PE1912 NOISO MFDHLTSNGHLSESEARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDANMNIKLA---- DANRE9_10_PE10 ISOFORMIN MFDYLTSNGRMSENEARKKFWQILTAVDYCHRHHIVHRDLKTENLLLDANMNIKLA---- DANRE9_10_PE9 ENSDARG00000058606 MFDYLTSNGRMSENEARKKFWQILTAVDYCHRHHIVHRDLKTENLLLDANMNIKLA---- DIPOR24691_PE1 NOISO MFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLA---- FELCAGS_3190_PE2 NOISO MFDYLTSNGHLSENEARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDGSMDIKLA---- FUGRU42_1_PE71 NOISO MFDFLTSHGRMSEDEARKKFWQILTAVDYCHRHHIVHRDLKTENLLLDANMNIKLA---- GASACGROUPXVI_8_PE88 NOISO MFDHLTTNGRMSEDEARKKFWQILTAVDYCHQHHIVHRDLKTENLLLDANMNIKLA---- GORGO21_33_PE9 NOISO MFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLA---- HORSE26_39_PE13 NOISO MFDYLTSNGHLSENEARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDGNMDIKLAGKGP HS21_PE783 NOISO MFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLA---- LOXAF67_11_PE8 NOISO MFDYLTSNGHLSEEEARKKFWQILSAVEYCHGHHIVHRDLKTENLLLDNNMDIKLA---- MACEUGS_5215_PE1 NOISO MFDYLTSNGHLSENEARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDASMNIKLA---- MACMU3_4_PE8 NOISO MFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLA---- MICMU10143_PE1 NOISO MFDYLTSNGHLSENEARKKFWQILSAVEYCHSHHVVHRDLKTENLLLDGNMDIKLAGK-- MONDO4_10_PE20 NOISO MFDYLTSNGHLSENEARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDASMNIKLA---- MOUSE17_PE914 NOISO MFDYLTSNGHLSENEARQKFWQILSAVEYCHNHHIVHRDLKTENLLLDSNMDIKLA---- MYOLUGS_2972_PE1 NOISO XXXXXXXXXXXXXXXXRKKFWQILSAVEYCHSHHIVHRDLKTENLLLDGNMDIKLAGE-- NEMVE_5053_PE7 NOISO MFDYLAHHGRLPEKEARKKFVQILSAVDYCHKRHVVHRDLKAENLLLDQNMNIKIAGMSG OCHPR24279_PE1 NOISO ------SHGHLSDEEARKKFCQILSAV-YCHSARIV-RDLRTKNLLLDADMDVKLA---- ORNANULTRA222_5_PE7 ENSOANG00000006466 MFDYLTSNGHLSENEARKKFWQILSAVDYCHSHHIVHRDLKTENLLLDANMNIKLA---- ORNANULTRA222_5_PE8 ISOFORMIN MFDYLTSNGHLSENEARKKFWQILSAVDYCHSHHIVHRDLKTENLLLDANMNIKLA---- ORYLA21_6_PE2 NOISO MFDYLTSNGRMSEDEARTKFWQILTAV-YCHRHHIVHRDLKTENLLLDGNMNIKLA---- OTOGA106538_PE1 NOISO MFDYLTSNGHLSEQEARKTFWQILSAVEYCHSHHIVHRDLKTENLLLDVNMDIKLAGK-- PANTR21_44_PE11 NOISO MFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLA---- POEGU1_5_PE12 NOISO MFDHLTSNGHLSESEARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDANMNIKLA---- POEGUUN_26_PE2 NOISO MFDHLTSNGHLSESEARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDANMNIKLA---- PONPY21_46_PE1 NOISO MFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLA---- PROCAGS_3809_PE1 NOISO MFDYLTSNGHMSEEEARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDTNMDIKLA---- PTEVA15161_PE1 NOISO EMHYLTSNGHLRESEARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDGNMDIKLA---- RAT20_PE448 NOISO MFDYLTSNGHLSENEARKKFWQILSAVEYCHNHHIVHRDLKTENLLLDGNMDIKLA---- SPETRGS_2922_PE1 NOISO XXXYLTSKRHLSENEARKKFRQILSAVEYCHNHHIVHRDLKTENLLLDSNMDIKLAGEG- TETNG2_PE879 NOISO MFDFLTSHGRMSEAEARTAFWQILTAVDYCHRHHIVHRDLKTENLLLDANMNIKLA---- TURTR106893_PE1 NOISO MFDYLTSTGHLSESEARKKFWQILSAVEYCHSHNIVHRDLKTENLLLDGNMDIKLA---- XENTR1084_PE7 ISOFORMIN LFDYLTARGRLTEQEARHKFLQILSAVEFCHAHCVVHRDLKAENLLLTDNMDLKLP---- XENTR1084_PE8 ENSXETG00000013685 LFDYLTARGRLTEQEARHKFLQILSAVEFCHAHCVVHRDLKAENLLLTDNMDLKLP---- XENTR1084_PE9 ISOFORMIN LFDYLTARGRLTEQEARHKFLQILSAVEFCHAHCVVHRDLKAENLLLTDNMDLKLP---- MATCH * * *: :** :** :* ***:.:*:** .:::*: CONSENSUS MFD?LTS?G?LSE?EARKKFWQILSAV?YCH?HHIVHRDLKTENLLLD?NM?IKLA????

AILMEGL194603_1_PE1 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV ANOCA118_1_PE4 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPHLDIWSLGVV BOVIN1_151_PE19 NOISO -------------DFGFGNFYNPGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV CALJA21_49_PE3 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV CANFA31_40_PE24 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV CAOWC1_1_8257 NOISO -------------DFGLSNFYSRGKFLSTFCGSPPYAAPELYQRQPYEGPEVDIWSLGVI CAVPO90_4_PE5 NOISO -------------DFGFGNFYKPGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV CHICK1_PE1912 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPHLDIWSLGVV DANRE9_10_PE10 ISOFORMIN -------------DFGFGNFYNAGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV DANRE9_10_PE9 ENSDARG00000058606 -------------DFGFGNFYNAGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV DIPOR24691_PE1 NOISO -------------DFGFGNFYNPGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV FELCAGS_3190_PE2 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV FUGRU42_1_PE71 NOISO -------------DFGFGNFYNAGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV GASACGROUPXVI_8_PE88 NOISO -------------DFGFGNFYNAGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV GORGO21_33_PE9 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV HORSE26_39_PE13 NOISO ----------AREDFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDVWSLGVV HS21_PE783 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV LOXAF67_11_PE8 NOISO -------------DFGFGNFYKSGEALSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV MACEUGS_5215_PE1 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPHLDIWSLGVV MACMU3_4_PE8 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV MICMU10143_PE1 NOISO ------------EDFGFGNFYKPGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV MONDO4_10_PE20 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPHLDIWSLGVV MOUSE17_PE914 NOISO -------------DFGFGNFYKPGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDVWSLGVV MYOLUGS_2972_PE1 NOISO ------------EDFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV NEMVE_5053_PE7 NOISO LYLVIHCILFSSLDFGFGNYYKPGNPLNTWCGSPPYAAPEH----IYCEPKVDFWPLGVV OCHPR24279_PE1 NOISO -------------DFGFGNFYNPGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV ORNANULTRA222_5_PE7 ENSOANG00000006466 -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPLLDVWSLGVV ORNANULTRA222_5_PE8 ISOFORMIN -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPLLDVWSLGVV ORYLA21_6_PE2 NOISO -------------DFGFGNFYNAGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV OTOGA106538_PE1 NOISO ------------EDC--WNFYKLGEPLSTWGS--LYAAPEVFEGKEYEGPQLDVWSLGVV PANTR21_44_PE11 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV POEGU1_5_PE12 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPHLDIWSLGVV POEGUUN_26_PE2 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPHLDIWSLGVV PONPY21_46_PE1 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV PROCAGS_3809_PE1 NOISO -------------DFGFGNFCKSGEALSKWSGSPQYAAPEVXXXXXXXXXXXXXXXXXXX PTEVA15161_PE1 NOISO -------------DFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV RAT20_PE448 NOISO -------------DFGFGNFYKPGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV SPETRGS_2922_PE1 NOISO -------------DFGFGNFYNPGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV TETNG2_PE879 NOISO -------------DFGFGNFYNAGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV TURTR106893_PE1 NOISO -------------DFGFGNFYKPGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV XENTR1084_PE7 ISOFORMIN ------------EDFGFGNFYKEGQALNTWCGSPPYAAPEVFQGQEYEGPPLDVWSLGVV XENTR1084_PE8 ENSXETG00000013685 ------------EDFGFGNFYKEGQALNTWCGSPPYAAPEVFQGQEYEGPPLDVWSLGVV XENTR1084_PE9 ISOFORMIN ------------EDFGFGNFYKEGQALNTWCGSPPYAAPEVFQGQEYEGPPLDVWSLGVV MATCH * *: . *: *..: . ***** CONSENSUS ?????????????DFGFGNFY??GEPLSTWCGSPPYAAPEVFEGKEYEGP?LD?WSLGVV

AILMEGL194603_1_PE1 NOISO LYVLVCGSLPFDGPDLPALRQRVLEGRFRIPFFMSQ------DCETLIR----RMLVVDP ANOCA118_1_PE4 NOISO LYVLVCGSLPFDGPNLPSLRQRVLEGRFRIPYFMSQ------DCETLIR----RMLVVDP BOVIN1_151_PE19 NOISO LYVLVCGSLPFDGPNLPALRQRVLEGRFRIPFFMSR------DCETLIR----RMLVVEP CALJA21_49_PE3 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCESLIR----RMLVVDP CANFA31_40_PE24 NOISO LYVLVCGSLPFDGPNLPALRQRVLEGRFRIPFFMSQ------DCETLIR----RMLVVDP CAOWC1_1_8257 NOISO LYVLVTGELPFDSTDQEELKQNILQAKYAAPEGVDP------ACVELIG----MMLQPDR CAVPO90_4_PE5 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCEMLIR----RMLVVDP CHICK1_PE1912 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPYFMSE------DCETLIR----RMLVVDP DANRE9_10_PE10 ISOFORMIN LYVLVCGSLPFDGDSLPALRQRVTEGRFRIPFFMSQ------DCENLIR----KMLVVDP DANRE9_10_PE9 ENSDARG00000058606 LYVLVCGSLPFDGDSLPALRQRVTEGRFRIPFFMSQ------DCENLIR----KMLVVDP DIPOR24691_PE1 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCETLIR----RMLAVDP FELCAGS_3190_PE2 NOISO LYVLVCGSLPFDGPNLPAXXXXXXXXXXXXXXXXXX------XCETLIR----RMLVVDP FUGRU42_1_PE71 NOISO LYVLVCGSLPFDGASLPALRQRVTEGRFRIPFFMSQ------DCENLIR----KMLVVDP GASACGROUPXVI_8_PE88 NOISO LYVLVCGSFPFDGPGLPALRQRVTEGRFRIPFFMSQ------DCENLIR----KMLVVDP GORGO21_33_PE9 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCESLIRRMIRRMLVVDP HORSE26_39_PE13 NOISO LYVLVCGSLPFDGPNLPALRQRVLEGRFRIPFFMSQ------DCETLIR----RMLVVDP HS21_PE783 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCESLIR----RMLVVDP LOXAF67_11_PE8 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCESLIR----RMLVVDP MACEUGS_5215_PE1 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFYMSQ------DCETLIR----RMLVVDP MACMU3_4_PE8 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCESLIR----RMLVVDP MICMU10143_PE1 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCESLIR----RMLVVDP MONDO4_10_PE20 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFYMSQ------DCETLIR----RMLVVDP MOUSE17_PE914 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCETLIR----RMLVVDP MYOLUGS_2972_PE1 NOISO LYVLVCGSLPFDGPSLPALRQRVLEGRFRIPFFMSR------DCETLIR----RMLVVDP NEMVE_5053_PE7 NOISO LYVLVCGALPFDGSTLQALRDRVLEGKFRIPFFMST------ECEHLIR----HMLVKDP OCHPR24279_PE1 NOISO LYVLVCGSLPFDGPTLPSLRQRVLEGRFRIPFFMSQ------DCESLLR----RMLVVDP ORNANULTRA222_5_PE7 ENSOANG00000006466 LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCESLIR----RMLVVDP ORNANULTRA222_5_PE8 ISOFORMIN LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCESLIR----RMLVVDP ORYLA21_6_PE2 NOISO LYVLVCGSLPFDGPSLPALRQRVTEGRFRIPFFMSQ------DCENLIR----KMLVVDP OTOGA106538_PE1 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCETLIR----RMLVVDP PANTR21_44_PE11 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCESLIR----RMLVVDP POEGU1_5_PE12 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPYFMSEVCLCHPNCETLIR----RMLVVDP POEGUUN_26_PE2 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPYFMSE------DCETLIR----RMLVVDP PONPY21_46_PE1 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCESLIR----RMLVVDP PROCAGS_3809_PE1 NOISO XXXXXXXXXXXX------XXXXXXXXXXXXXXXXXXXXXXXXXCESLIR----RMLVVDP PTEVA15161_PE1 NOISO MYVLVCGSLPFDGPSLL-LRHQVLDGRFRVPFFMSR------DCEALIR----RMLAVDP RAT20_PE448 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCETLIR----RMLVVDP SPETRGS_2922_PE1 NOISO LYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQ------DCETLIR----RMLVVDP TETNG2_PE879 NOISO LYVLVCGSLPFDGPSLPALRQRVTEGRFRIPFFMSQ------DCENLIR----KMLVVDP TURTR106893_PE1 NOISO LYVLVCGSLPFDGPSLPALRQRVLEGRFRIPFFMSR------DCETLVR----RMLAVDP XENTR1084_PE7 ISOFORMIN LYVLLCGTFPFDAPNLPTLRQRVLEGRFRIPYFMSQ------DCESLIR----RMLVVDP XENTR1084_PE8 ENSXETG00000013685 LYVLLCGTFPFDAPNLPTLRQRVLEGRFRIPYFMSQ------DCESLIR----RMLVVDP XENTR1084_PE9 ISOFORMIN LYVLLCGTFPFDAPNLPTLRQRVLEGRFRIPYFMSQ------DCESLIR----RMLVVDP MATCH * *: ** : CONSENSUS LYVLVCGSLPFDGP?LP?LRQRVLEGRFRIP?FMS???????DCE?LIR????RMLVVDP

AILMEGL194603_1_PE1 NOISO AKRITIAQIRQHRWMQAGPSVPRQ--------ACPTFSAPGPGPGSGSGRGHYDEQALGI ANOCA118_1_PE4 NOISO TKRITIAQIKQHKWILADPSLQQHQ--------SLSFSMHSY----NSNLGDYNEQVLGI BOVIN1_151_PE19 NOISO AKRITIAQIRQHRWMQAEPALVLP--------ACPGFSLLGY----TSSVGDYDEQALGI CALJA21_49_PE3 NOISO ARRISIAQIRQHRWMRAEPCLPEPCL----GPACPAFSAHSY----SSNLGDYDEQALGI CANFA31_40_PE24 NOISO TKRITIAQIRQHRWMQADPSVPRQ--------ACPALSALS----YNSNLGHYDEQVLGI CAOWC1_1_8257 NOISO ALRCTMADIRAHRWMNNKEEDFYAE-----------IEAAAW----ADEDDEMCAFALRI CAVPO90_4_PE5 NOISO AKRITIAQIWQHRWMQADPTLLQQ--------ADPALSMLGY----TSNLGDYNEQALGI CHICK1_PE1912 NOISO TKRITISQIKQHKWMQADPSLRQQQ--------SLSFSMQNY----NSNLGDYNEQVLGI DANRE9_10_PE10 ISOFORMIN AKRITIAQIKQHRWMLADPSAPHQ---------TLSLSLTDY----NSNLGDYSEPVLGI DANRE9_10_PE9 ENSDARG00000058606 AKRITIAQIKQHRWMLADPSAPHQ---------TLSLSLTDY----NSNLGDYSEPVLGI DIPOR24691_PE1 NOISO TKRISIAQIRQHRWMQADPRPR----------PGPALSTQAY----SSNLGDYNEQALGI FELCAGS_3190_PE2 NOISO SKRITIAQIRQHRWMQAEPPVPRQ--------ACTAFSALSY----NASPGRYDEQVLGI FUGRU42_1_PE71 NOISO TRRITVAQIKQHRWMLADPTAARQ---------ILSHSLTEY----NSNLGDYSEPVLSI GASACGROUPXVI_8_PE88 NOISO ARRISVAQIKQHRWMLADPTAARQ---------TLSHSLTEY----NSNLGDYSEPVLGI GORGO21_33_PE9 NOISO ARRITIAQIRQHRWMRAEPCLP--------GPACPAFSAHSY----TSNLGDYDEQALGI HORSE26_39_PE13 NOISO AKRITVAQIRQHRWMQADPSLLRQ--------ACPAFSALSY----NSNLGDYDEQVLGI HS21_PE783 NOISO ARRITIAQIRQHRWMRAEPCLP--------GPACPAFSAHSY----TSNLGDYDEQALGI LOXAF67_11_PE8 NOISO AKRITVAQIKQHRWMQAEPTRPQP--------SSLAFLAHDY----NSHLGDYNEQVLGI MACEUGS_5215_PE1 NOISO TKRITIAQIKHHKWMLADPSFPE---------STLSFSIQNY----SSNLGDYNEQVLGI MACMU3_4_PE8 NOISO ARRITIAQIRQHRWMRAEPCLP--------GPACSTFSAHSY----SSNLGDYDEQALGI MICMU10143_PE1 NOISO AKRITLAQIRQHRWMQAAPSLLRQ--------PPLACPAHGC----SASPGDPDERVLGI MONDO4_10_PE20 NOISO AKRITIAQIKHHKWMQADPSLPRSP--------GLAFSVHNY----SSNLGDYNEQVLGM MOUSE17_PE914 NOISO AKRITIAQIRQHRWMQADPTLLQQ--------DDPAFDMQGY----TSNLGDYNEQVLGI MYOLUGS_2972_PE1 NOISO AKRISIAQIRQHKWMQADPTLPLT---------RPTSAALSY----NSNLGDYDEQVLGI NEMVE_5053_PE7 NOISO NQRYTIEQIQKHKWLQAADSQKIS---------EIEQSMREF---EKISMEDYNEQALEL OCHPR24279_PE1 NOISO TKRITIAQIWQHRWVQADPGLPGA---------HAARTLHSY----DSSLGDYDEQVLGV ORNANULTRA222_5_PE7 ENSOANG00000006466 AKRITVAQIKQHRWMQTGPALQQPQHQQPPPPSPLCFALHGY----NSNLGDYDEQVLGI ORNANULTRA222_5_PE8 ISOFORMIN AKRITVAQIKQHRWMQTGPALQQPQHQQPPPPSPLCFALHGY----NSNLGDYDEQVLGI ORYLA21_6_PE2 NOISO ARRISVAQIKQHRWMLADPAAAHQ---------TLCHSLTDY----NSNLGDYSEPVLGI OTOGA106538_PE1 NOISO AKRITIAQIRQHRWMQADPALLRQ--------ASLASPAHSC----SSTLGEPDEQVLGI PANTR21_44_PE11 NOISO ARRITIAQIRQHRWMRAEPCLP--------GPACPAFSAHSY----TSNLGDYDEQALGI POEGU1_5_PE12 NOISO TKRITISQIKQHKWMQADPSLQQQQ--------SLCFSMQNY----NSNLGDYNEQVLGI POEGUUN_26_PE2 NOISO AKRITISQIKQHKWMQADPSLQQQQ--------SLCFSMQNY----NSNLGDYNEQVLGI PONPY21_46_PE1 NOISO ARRITIAQIRQHRWMRAEPCFP--------GPACPTFSAHSY----SSNLGDYDEQALGI PROCAGS_3809_PE1 NOISO AKRITVAQIKQHRWMQAEPTLSQS--------TSLAFVAQDY----NSNLGDYNEQVLGI PTEVA15161_PE1 NOISO ARRISIAQIRQHRWMQAGPAP--PCV----SPAGP-------ALGCNSNLGGYDEQVLGF RAT20_PE448 NOISO AKRITIAQIRQHRWMQADPTLLQQ--------DDPAFSMQGY----TSNLGDYNEQVLGI SPETRGS_2922_PE1 NOISO AKRITIAQIWQHRWMQADPSLLQQ--------ADPTFSVHSY----TSNLGDYNEQVLGI TETNG2_PE879 NOISO SRRITVAQIKQHRWMLADPAAARQ---------VLTRSLTEY----NSNLGDYSEPVLSV TURTR106893_PE1 NOISO TKRITISQIWEHRWMRADPALRQP--------TCPVFSLLGY----ASSLGSYDEQALGI XENTR1084_PE7 ISOFORMIN AKRLTIGQIKQHRWVQTGDYLPPIPDALSPA--------------------PPCLQVLSL XENTR1084_PE8 ENSXETG00000013685 AKRLTIGQIKQHRWVQTGDYLPPIPDALSPA--------------------PPCLQVLSL XENTR1084_PE9 ISOFORMIN AKRLTIGQIKQHRWVQTGDYLPPIPDALSPA--------------------PPCLQVLSL MATCH * :: :* *:*: .* . CONSENSUS ??RIT?AQI?QHRWM?A?P????????????????????????????S??G?Y?EQ?LGI

AILMEGL194603_1_PE1 NOISO MHSLGIDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRHPPAVRPPG------------- ANOCA118_1_PE4 NOISO MHTLGIDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRSNQLANRPV------------- BOVIN1_151_PE19 NOISO MQMLGVDRKKTVESLQKRSYNHFAAIYYLLVERLKEYRLTQP-ARPG------------- CALJA21_49_PE3 NOISO MQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQC-TRPG------------- CANFA31_40_PE24 NOISO MHTLGIDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRHTQ------------------- CAOWC1_1_8257 NOISO LTQVGYSEPIIINSLVINCLDDICASYNFILERLRRMDVEEWPAFEESYIRLFQLEPDAS CAVPO90_4_PE5 NOISO MQALGIDRKKTVESLQNSSYNHFAAIYYLLLERLKEHRGAQPLARPV------------- CHICK1_PE1912 NOISO MQTLGIDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRSSQLSSRPA------------- DANRE9_10_PE10 ISOFORMIN MQTLGIDRQRTVESLQNSSYNHFSAIYYLLLERVKEHRSQQISRQCG------------- DANRE9_10_PE9 ENSDARG00000058606 MQTLGIDRQRTVESLQNSSYNHFSAIYYLLLERVKEHRSQQISRQCG------------- DIPOR24691_PE1 NOISO MQALGIDRQRTVESLQNSSYNHFAAIYYLLLERLREHRSSQLPARPL------------- FELCAGS_3190_PE2 NOISO MHTLGIDRQRTVESLQNSSYNHFAAIYYLLLERLKEHRHTQPSARPG------------- FUGRU42_1_PE71 NOISO MNTLGIDRQKTIESLQSSSYNHFSAIYYLLLERVREHRTQQLSRQCG------------- GASACGROUPXVI_8_PE88 NOISO MSTLGINRQKTIESLQSSSYNHFSAIYYLLLERVREHRNQQLSRQCG------------- GORGO21_33_PE9 NOISO MQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQC-ARPG------------- HORSE26_39_PE13 NOISO MQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQPSARPG------------- HS21_PE783 NOISO MQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQC-ARPG------------- LOXAF67_11_PE8 NOISO MQTLGIDRRRTVESLQDSSYNHFAAIYYLLLERLKEYRSSQLPARPG------------- MACEUGS_5215_PE1 NOISO MQTLGINRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNTQPSNCSG------------- MACMU3_4_PE8 NOISO MQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQC-ARPG------------- MICMU10143_PE1 NOISO MQTLGIDRQRTVESLQSRSYNHFAAIYYLLLERLQEHRNTPC-ARPG------------- MONDO4_10_PE20 NOISO MQTLGISKQRTVESLQNSSYNHFAAIYYLLLERLKEYRSTQPSTCSG------------- MOUSE17_PE914 NOISO MQALGIDRQRTIESLQNSSYNHFAAIYYLLLERLKEHRSAQPSSRPT-----------PA MYOLUGS_2972_PE1 NOISO MQTLGVDRQRTMESLQNSSYNHFAAIYYLLLERLKEYRNTPPSARPG------------- NEMVE_5053_PE7 NOISO MKGLGIDIKRTKKALDDNTFDHHTAIYYLLVDRLRLHRASYPAEEQC------------- OCHPR24279_PE1 NOISO MRNLGIDRQRTLESLQNRSYNHFAAIYYLLRERLQPR----APARPG------------- ORNANULTRA222_5_PE7 ENSOANG00000006466 MQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEHRSSQLPGRPG------------- ORNANULTRA222_5_PE8 ISOFORMIN MQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEHRSSQLPGRPG------------- ORYLA21_6_PE2 NOISO MNTLGIDRQRTIESLQSSSYNHFSAIYYLLLERVREHRAQQLSRQCG------------- OTOGA106538_PE1 NOISO MQTLGIDRQRTVEXXXXXXYNHFAAIYFLLLERLQEYRSTQG-TRPG------------- PANTR21_44_PE11 NOISO MQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQC-ARPG------------- POEGU1_5_PE12 NOISO MQTLGIDRQRTVESLQNSSYNHFAAIYYLLLERLKEYWSSQVSTRPA------------- POEGUUN_26_PE2 NOISO MQTLGIDRQRTVESLQNSSYNHFAAIYYLLLERLKEYWSSQVSTRPA------------- PONPY21_46_PE1 NOISO MQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQC-ARPG------------- PROCAGS_3809_PE1 NOISO MQMLGIDRRRTVESLQNSSYNHFAAIYYLLLERLKEYRSSQC-VRPG------------- PTEVA15161_PE1 NOISO MQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLRGHRGSPPLARSG------------- RAT20_PE448 NOISO MQALGIDRQRTVESLQNSSYNHFAAIYYLLLERLREHRSTQPSSRAT-----------PA SPETRGS_2922_PE1 NOISO MQALGIDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRSTQPSARPG------------- TETNG2_PE879 NOISO MNTLGIDRQKTIESLQSSSYNHFSAIYYLLLERVREHRTQQLSRQCG------------- TURTR106893_PE1 NOISO MQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKELRLAQR-ARPG------------- XENTR1084_PE7 ISOFORMIN MQSLGIDRERTLQALRNDSYNHYAAIYFLLVERLQEPRLGALT-PPS-----------PG XENTR1084_PE8 ENSXETG00000013685 MQSLGIDRERTLQALRNDSYNHYAAIYFLLVERLQEPRLGALT-PPS-----------PG XENTR1084_PE9 ISOFORMIN MQSLGIDRERTLQALRNDSYNHYAAIYFLLVERLQEPRLGALT-PPS-----------PG MATCH : :* . : :. * * :: :*:: CONSENSUS M??LG?DR?RT?ESLQ??SYNHFAAIYYLLLERL?E?R??????????????????????

AILMEGL194603_1_PE1 NOISO PARQQRPRS-SDLSGFEVPQEGLSGDSFRSSLLC---PQPQTLGQSVLQADTDCDPLSSF ANOCA118_1_PE4 NOISO SSRQQRPRS-SDFSNIELPQDSLAGETLRSSLMY---QQPQNLIQSHLQAEMDCDMNNPL BOVIN1_151_PE19 NOISO PARQQRPRS-TDLSGFEVPQEGLPGDALRSALLC---TQPQTLGQSVLQAEMDYDLHSSL CALJA21_49_PE3 NOISO PARQPRPRS-SDLSGLEVPREGFSADPFRPALLC---PQPQALVQSVLQAEMDCELQGSL CANFA31_40_PE24 NOISO --PQQRPRS-SDLSGFEVTQEAFSGDPFRSSLLC---PQPQALGPSVLHADTDCDPLSSL CAOWC1_1_8257 NOISO KNLPLDP-SSNPGSAATTPQKPAPPSPFRPAQASGSNPSL--LE-------SLRALSS-- CAVPO90_4_PE5 NOISO PTRQPRPRS-SDLGGLEVPPEGLPIDPLRSSLLC---PQPQVLVQSVLQAEMDCDLHSSL CHICK1_PE1912 NOISO TGRQQRPRS-SEISNAEMPQDSLTSETLRSSLLY---QQPQSLIQPSLQAEMDCDMNNPL DANRE9_10_PE10 ISOFORMIN -AWNQRSRTASDSSTPEVIMES--SDSFRNSAFP---VATKVNA--PIHSEMECEQGG-- DANRE9_10_PE9 ENSDARG00000058606 -AWNQRSRTASDSSTPEVIMES--SDSFRNSAFP---VATKVNA--PIHSEMECEQGG-- DIPOR24691_PE1 NOISO PARQPRPRS-SDLSGLEAPHDGFPSDPFRPSLLC---PQPQALAQSVLQAELDCDL---- FELCAGS_3190_PE2 NOISO LARQQRPRS-SDLGGFEVPQEGLSGDSFQPSLLC---PQPQAFGQSVLQADTDCDPLSSL FUGRU42_1_PE71 NOISO -TWGQRPRSTSDTSSPETIVES--TDNFRSAAFS---MPPKSST--PPSLHSEKDFEQGG GASACGROUPXVI_8_PE88 NOISO -TWSQRPRSSSDTTGPEVIMES--TDSFRSTAFS---IPAKSTP--QVYPEMEYDQIQLL GORGO21_33_PE9 NOISO PARQPRPRS-SDLSGLEVPQEGLSTDPFRPAFLC---PQPQTLVQSVLQAEMDCELQSSL HORSE26_39_PE13 NOISO PARQPRPRS-SDLSGFEVPQEGLPGDAFRSALLC---PQPQSLGQSVLQAEMDCDLHSSL HS21_PE783 NOISO PARQPRPRS-SDLSGLEVPQEGLSTDPFRPALLC---PQPQTLVQSVLQAEMDCELQSSL LOXAF67_11_PE8 NOISO PTRQPRPRS-SELGGFEVPQEGLTGDPFHLPLLC---PQPQTLGQSVLQVEMDCDLSTSL MACEUGS_5215_PE1 NOISO LGRLQRSRS-SDFSNFEMPQECLTSDALRSSLLY---QQPQNLTQSMLQEEMDFDLNNPL MACMU3_4_PE8 NOISO PARQPRPRS-SDLSGLEVPQEGLSTDPFRPALLC---PQPQTLVQSVLQAELDCELQSSL MICMU10143_PE1 NOISO PARPHRPRS-SDLSGFEVPQEGLPADPFRSVLLC---PQPPALAQSVLQAEMDCDLHSSL MONDO4_10_PE20 NOISO PGELPRSRS-SDPSPLETPPEGLAADAFRSSLLP---QHPQSLAPAVLQEAMDFDLNHPL MOUSE17_PE914 NOISO PTRQPQLRS-SDLSSLEVPQEILPCDPFRPSLLC---PQPQALAQSVLQAEIDCDLHSSL MYOLUGS_2972_PE1 NOISO PARQQRPRS-SDHSSLEVPQEGLPGDAFRSSLLC---SQPQTLGQSILQAEMDCDLHSSL NEMVE_5053_PE7 NOISO ETKLRRPSGIAEA---AVVRNNIEKGT---TLQE---THP-------------------- OCHPR24279_PE1 NOISO PCRPHGPSS-PDLHGFEAPPEGLAAGPFPSSLLC---PQP--LAQSVLQTEVDYDLHKTL ORNANULTRA222_5_PE7 ENSOANG00000006466 TTRRHRPRS-SELSSFEIPPEALSSESLRSTLLY---QPPQPLTQSVLQAEMDCDLNNPL ORNANULTRA222_5_PE8 ISOFORMIN TTRRHRPRS-SELSSFEIPPEALSSESLRSTLLY---QPPQPLTQSVLQAEMDCDLNNPL ORYLA21_6_PE2 NOISO -SWSQRPRSTSDSSGTEGIMEI--SDSFRSTPFP---AKSAPS---AAYSEVECDQGG-- OTOGA106538_PE1 NOISO PARQHRPRS-SDLSGFEVPQEGLPVDPLRVTLLC---PQPQTLAQSVLQAEMDCDLHSSL PANTR21_44_PE11 NOISO PARQPRPRS-SDLSGLEVPQEGLSTDPFRPALLC---PQPQTLVQSVLQAEMDCELQSSL POEGU1_5_PE12 NOISO AGRQPRPRS-SEIANAEMPQDSLTSETLRSSLLY---QQPQSLIQPSLQAEMDCDISNPL POEGUUN_26_PE2 NOISO AGRQPRPRS-SEIASAEMPQDSLTSETLRSSLLY---QQPQSLIQPSLQAEMDCDISNPL PONPY21_46_PE1 NOISO PARQPRPRS-SDLSSLEVPQEGLSTDPFRPALLC---PQPQTLVQSVLQAEMDCELQSSL PROCAGS_3809_PE1 NOISO PARQPRPRS-SELSSFEIPQEGLIGEPLRLPLLC---PQPQTL-QSVLQVEMDCDLSTSL PTEVA15161_PE1 NOISO PALQQRPRS-ADHSAVEVPQEGLPGDAFRSPVLC---PQPQTLGQSILQAEMDCELHSSL RAT20_PE448 NOISO PARQPQLRN-SDLSSLEVPQEILPCDPFRPSLLC---PQPQALAQSVLQAEIDCDLHSSL SPETRGS_2922_PE1 NOISO PARPPRPRS-SDLSSCEVTQDSLPGDPFRSSLLC---PQPQALAQSVLQAEMDCDLQSSL TETNG2_PE879 NOISO -TWSQRPRSTSDSSGPEVSAAA--RPKAPLLPHL---RCPRRRT--T---SRAGCSRAPI TURTR106893_PE1 NOISO HAWQQRPRS-SDLSGFEVPQEGPPGDAFRSALLC---AQPQTLGQSVLQAELDCDLHGSL XENTR1084_PE7 ISOFORMIN PAAQN-PPSCDHVSAWGCIRDSLLMLSLKTTAHPNPVPHPKIDEIDPKETNKI------- XENTR1084_PE8 ENSXETG00000013685 PAAQN-PPSCDHVSAWIVPPQVPPP---------GTAGSPLVCGPQAAPTDCDCGLSFPL XENTR1084_PE9 ISOFORMIN PAAQN-PPSCDH------------------------------------------------ MATCH CONSENSUS ?????RPRS?S?????E???????????R??????????P????????????????????

AILMEGL194603_1_PE1 NOISO Q---PLLFPLDTNCNGVFRHR----SISPSGLLDTSISEEVR------------------ ANOCA118_1_PE4 NOISO Q---PVFFPVDPNFNSLFRNR----SISPNSLLETTISEEVR------------------ BOVIN1_151_PE19 NOISO Q---PLMFPVDTSFGGVCRHR----SISPSSLLDTAISEEAR------------------ CALJA21_49_PE3 NOISO Q--WPLFFPVDAGCSGVFRPR----PLSPSSLLDTAISEEAR------------------ CANFA31_40_PE24 NOISO Q---PLLFPLDANCNGVFRHR----PISPNGLLDAPISEEVG------------------ CAOWC1_1_8257 NOISO ------------------------------------------------------------ CAVPO90_4_PE5 NOISO Q---PLFFAGDTNGTGMFPHR----SISPSSLLDTAISEEAR------------------ CHICK1_PE1912 NOISO Q---PVFFPVDPNFNGLFRNR----SISPSSLLETTISEEVR------------------ DANRE9_10_PE10 ISOFORMIN L-FQRVVCPVEASLNGLLWNR----SISPNSLLETTISEEVR------------------ DANRE9_10_PE9 ENSDARG00000058606 L-FQRVVCPVEASLNGLLWNR----SISPNSLLETTISEEVR------------------ DIPOR24691_PE1 NOISO Q--YPLFFSMDANCNGVLRHR----PTSPSSLLDTAISEEAR------------------ FELCAGS_3190_PE2 NOISO Q--CPLLFPLDANCNGVFRNR----PISPSGLLDASI----------------------- FUGRU42_1_PE71 NOISO L-FQRVVFPVEASLNRLLWNR----SISPNSLLETSISEEVR------------------ GASACGROUPXVI_8_PE88 NOISO P-FQRVVFPAEASLNRLLWNR----SISPNSLLETSISEEVR------------------ GORGO21_33_PE9 NOISO Q--WPLFFPVDASCSGVFRPR----PVSPSSLLDTAISEEAR------------------ HORSE26_39_PE13 NOISO Q---PLFFPVDTNCNGVFRHR----SISPTSLLDTTISEEVR------------------ HS21_PE783 NOISO Q--WPLFFPVDASCSGVFRPR----PVSPSSLLDTAISEEAR------------------ LOXAF67_11_PE8 NOISO Q---PLFFSVDANCDGMSHHR----SVSPSSLLDTAISEEAR------------------ MACEUGS_5215_PE1 NOISO Q---PLFFSMEPNFSGLFRPC----SISPN-LLETTISEEVR------------------ MACMU3_4_PE8 NOISO Q--WPLFFPVDASCSGVFRPR----PVSPSSLLDTAISEEAR------------------ MICMU10143_PE1 NOISO Q---PLFFPLDANCNAVFRHR----PVSPSSLLDTAISEEAR------------------ MONDO4_10_PE20 NOISO Q---PLFFSADPSVSGLLRNG----FISPNSLLETTISEEVR------------------ MOUSE17_PE914 NOISO Q---PLLFPLDTNCSGVFRHR----SISPSSLLDTAISEEAR------------------ MYOLUGS_2972_PE1 NOISO Q--GXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXX------------------ NEMVE_5053_PE7 NOISO ------------------------------------------------------------ OCHPR24279_PE1 NOISO Q--FPLLFPGDASCHSMLQPH----PVSPVPLLDCTVGEEAR------------------ ORNANULTRA222_5_PE7 ENSOANG00000006466 Q--QPLFFPVDPNLNGLLRNR----PISPNSLLETTISEEVR------------------ ORNANULTRA222_5_PE8 ISOFORMIN ---QPLFFPVDPNLNGLLRNR----PISPNSLLETTISEEVR------------------ ORYLA21_6_PE2 NOISO L-FQRVVFPVEASLNRLLWNR----SISPNSLLETSISEEVR------------------ OTOGA106538_PE1 NOISO Q--CPLFFPVDTNCNGVFRHR----PISLSSLLDTAISEEAR------------------ PANTR21_44_PE11 NOISO Q--WPLFFPVDASCSGVFRPR----PVSPSSLLDTAISEEAR------------------ POEGU1_5_PE12 NOISO Q---PVFFPVDTNFNGLFRNR----SISPNSLLETTISEEVR------------------ POEGUUN_26_PE2 NOISO Q---PGVFPVDTT-HGLFRNR----STSPTVLLET------------------------- PONPY21_46_PE1 NOISO Q--WPLFFPVDASCSGVFRPR----PVSPSSLLDTAISEEAR------------------ PROCAGS_3809_PE1 NOISO QVSCPLFFPVDANCDGLFRHR----SVSPSSLLDTAISEEAR------------------ PTEVA15161_PE1 NOISO Q--CPLLFPVDTSCSGVLRHR----SVSPSGLLDTTISEEVR------------------ RAT20_PE448 NOISO Q---PLFFPLDTNCSGVFRHR----SISPSSLLDTAISEEAR------------------ SPETRGS_2922_PE1 NOISO Q--VPLFFPVDVNCNGVFQHR----PVSPSSLLDTAISGEAR------------------ TETNG2_PE879 NOISO C-LQRVVFPVEASLNRLLWNR----SISPNSLLETSISEEVR------------------ TURTR106893_PE1 NOISO Q--CPSLFPVDTGCHGVCQWR----SVSPSSLLDTAISEEAR------------------ XENTR1084_PE7 ISOFORMIN ----------VGICRGAEK-IPPNM-------NLRKRNRAV----------SRSC-LCCI XENTR1084_PE8 ENSXETG00000013685 Q---SMLYLEEPPCAGSSAAVPPALPRAPPSCQEPKLHKEIPKVVPMSG----------- XENTR1084_PE9 ISOFORMIN ----SMLYLEEPPCAGSSAAVPPALPRAPPSCQEPKLHKEIPKVVPSKYPLILSCSHSRV MATCH CONSENSUS ???????F???????????????????SP??LL???I??E????????????????????

AILMEGL194603_1_PE1 NOISO --QGPGLEEEREAQKP---LSGSTGRRHTLAEVS-TCFSPCAPPC--IVIS-SSAASPAE ANOCA118_1_PE4 NOISO --QDKELEDEIKAFN-PIRLPINTSRRHTLAEVT-THFYQCSPPCIVISSS----TNGTE BOVIN1_151_PE19 NOISO --PGPGLDEEQEVQEP---LPSSTGRRHTLAEVS-TCFSPGAPPC--IVVS-PSVASPCE CALJA21_49_PE3 NOISO --QGPGLEEEQDAQES---LPGSTGRRHTLAEVS-SRLSPLTAPCI-VISP-SATASPAE CANFA31_40_PE24 NOISO --QAPGLEEEREAQKP---PSGSTARRHTLAEVS-TCFSPCAPPC--IVIS-SSTASPSE CAOWC1_1_8257 NOISO ------------------------------------------------------------ CAVPO90_4_PE5 NOISO --QGPSLEEEPEVQEL---LRGSTGRRHTLAEVS-THFSPLAPPCI-VVSS-SASAGTSE CHICK1_PE1912 NOISO --QEKELEDEIKAYDHPIRIPSNTSRRHTLAEVT-THFYQHAPPCIVISSS----ASPTE DANRE9_10_PE10 ISOFORMIN --PHDLVCLKTSDLY--------------------------------------------- DANRE9_10_PE9 ENSDARG00000058606 --PHDLEEEEGILQVQPPHLPSTTSRRHTLAEVSTSRFHQCSPPCIVV--------SPSD DIPOR24691_PE1 NOISO --QGPGLEEEHEAQEP---LAGSTGRRHTLAEVS-THF-PLAPPCI-VVSC-SASASPSE FELCAGS_3190_PE2 NOISO ------------------------------------------------------------ FUGRU42_1_PE71 NOISO --PRDLEEEEATQTLGPLLPPTTTSRRHTLAEVS-TRFHQCIPPCIVV--------SPSD GASACGROUPXVI_8_PE88 NOISO --PRDLEEEEVTQTPGPLLPPTTTSRRHTLAEVS-ARFHQCSPPCIVV--------CPSD GORGO21_33_PE9 NOISO --QGLGLEEEQDTQES---LPSSTGRRHTLAEVS-TRLSPLTAPCI-VVSP-STTASPAE HORSE26_39_PE13 NOISO --QGQGLEEEQEAQMP---LPSSSGRRHTLAEVS-TCFSPGAPPCKCIVIS-SSVASPSE HS21_PE783 NOISO --QGPGLEEEQDTQES---LPSSTGRRHTLAEVS-TRLSPLTAPCI-VVSP-STTASPAE LOXAF67_11_PE8 NOISO --HGQGLEEELNAQKP----PSGTGRRHTLAEVT-AHFSPCTPPCIVISSSCATAAGPSE MACEUGS_5215_PE1 NOISO --QDKDEE-EMKAQN-PIHLPSNTSRRHTLAEVT-THFYQRTPPCIVISSC----ASPAE MACMU3_4_PE8 NOISO --QGPGLEEEQDVQES---LPSSTGRRHTLAEVS-TRLSPLTAPCI-VVSP-SASASPAE MICMU10143_PE1 NOISO --PGPGLEEEREAQEA---LPSSTGRRHTLAEVS-TRFSPLTPPCI-VVSP-SAVASPAE MONDO4_10_PE20 NOISO --QDQDLEEEVKAQHPGHPPSSTANRRHTLAEVT-SHLYQRSPPCIVISSC----TSPAE MOUSE17_PE914 NOISO --QGPSLEEEQEVQEP---LPGSTGRRHTLAEVS-THFSPLNPPCI-IVSS-SATASPSE MYOLUGS_2972_PE1 NOISO --XXXXXXXXXXXXXX---XXXXXXXXXXXXXXX-XXXXXXXXXXIVI--S-SSSASPSE NEMVE_5053_PE7 NOISO ------------------------------------------------------------ OCHPR24279_PE1 NOISO --QAPSPEEELDPQSP----VVSTVPRHTLAEVS-PRFSPLSPPRIVSG---SSTASPSE ORNANULTRA222_5_PE7 ENSOANG00000006466 --QEKDLEEEIRAQN-PFHLPGNTSRRHTLAEVT-THFYQSGPPCIVVSCS----ASPTE ORNANULTRA222_5_PE8 ISOFORMIN --QEKDLEEEIRAQN-PFHLPGNTSRRHTLAEVT-THFYQSGPPCIVVSCS----ASPTE ORYLA21_6_PE2 NOISO --PRDLVEEEATQAFGPLLPPTTTSRRHTLAEVS-ARFHQCNPPCIVV--------SPSD OTOGA106538_PE1 NOISO --QDPGLEEEQESQEP---LPSSTGRRHTLAEVS-ARFSPLTPPCI-IVSP-SAPARSGK PANTR21_44_PE11 NOISO --QGPGLEEEQDTQES---LPSSTGRRHTLAEVS-TRLSPLTAPCI-VVSP-STTASPAE POEGU1_5_PE12 NOISO --QEKELEDEIKAFDHPICIPSNTSRRHTLAEVT-THFYQHVPPCIVISSS----ASPTE POEGUUN_26_PE2 NOISO ------------------------------------------------------------ PONPY21_46_PE1 NOISO --QGPGLEEEQDTQES---LPSSTGRRHTLAEVS-TRLSPLTAPCI-VVSP-SATASPAE PROCAGS_3809_PE1 NOISO --XXXXXXXXXXXXXXXX---XXXXXXXXXXXXX-XXXXXXXXXXIVISASCAATAGSSE PTEVA15161_PE1 NOISO --QGPGPEEQREAQRP---LPGGTGRRHTLAEVS-T-FSPRAPPCVVV----SSSASPSE RAT20_PE448 NOISO --QGPSLEEEQEVQEP---LPGSTGRRHTLAEVS-THFSPLNPPCI-IVSS-SAAVSPSE SPETRGS_2922_PE1 NOISO --LGPGLEEEQEAREP---LPGSTGRRHTLAEVS-THFSPITPPCIVVSSS-STAATASE TETNG2_PE879 NOISO --PRDLEEEEATQTPS----SPTTSRRHTLAEVS-TRFHQCNPPCIVV--------SPSD TURTR106893_PE1 NOISO --RGPGLDEEQVARGP---PPGKAGRRHTLXXXS--------PGIPSIVVS-PSAASPSE XENTR1084_PE7 ISOFORMIN WKSPPVLGVQL--LYPRLCPGPPHPVRNQSYTRKFQRLFQVSIPSYSLAPT---RVSGSH XENTR1084_PE8 ENSXETG00000013685 ----------------------------SHSHSHSRVWLPLPLACLAPTLT---HVSPSQ XENTR1084_PE9 ISOFORMIN WLP-----------LPLACLAP-TPTRVSGSHSHSRVWLPLPLACLAPTPT---RVSGSH MATCH CONSENSUS ??????????????????????????R?????????????????????????????????

AILMEGL194603_1_PE1 NOISO G------TSSDSCLTF--SAGDGPAGLSG------RL----AAQGLLGTCSPLRLASPPL ANOCA118_1_PE4 NOISO G------TSSDSCLTS--SANDGSVTLSN------CL----EEQMMLGHPATTRVTSSFL BOVIN1_151_PE19 NOISO G------TSSDSCLT---SAGDGLAGLSG------HL----AAQGLVGACSPLRLASPLL CALJA21_49_PE3 NOISO G------TSSDSCLTF--SASRDPMELSG------TS----ATQGLLGAGSPVRLASPFL CANFA31_40_PE24 NOISO G------TSSDSCLTF--SAGDGPGALSG------RL----AAQGLVGTCSPLRLASPLL CAOWC1_1_8257 NOISO ------------------------------------------------------------ CAVPO90_4_PE5 NOISO G------TSSDSCLTF--SAGEGPAGFSG------GL----TTQGLLGTCSPVRMASPFL CHICK1_PE1912 NOISO G------TSSDSCLTS--SSNDSSVALSS------CL----AGQVMTGSPATARMTSAFL DANRE9_10_PE10 ISOFORMIN ------------------------------------------------------------ DANRE9_10_PE9 ENSDARG00000058606 G------ASSDSCLKS--SSNTNPPLSPVVGDFSSLLISGTGPGALGPAGTPLALSS--- DIPOR24691_PE1 NOISO G------TSSDSCLTF--SSSQGPEGLGG------GL----AAQGLLGACSCIRFPSPFL FELCAGS_3190_PE2 NOISO ------------------------------------------------------------ FUGRU42_1_PE71 NOISO G------ASSDSCLKS--SSSPAPSLQGVLGEISTPQASGAEGGALLSAGAPLALSS--- GASACGROUPXVI_8_PE88 NOISO G------ASSDGCLKS--SSSAVPTLREARGEMSTLLASGNKSGALLPAGAPLTVSS--- GORGO21_33_PE9 NOISO G------TSSDSCLTF--SASKSPAGLSG------TP----ATQGLLGACSPVRLASPFL HORSE26_39_PE13 NOISO G------TSSDSCLT---SAGDGLVGLSG------RL----ATQGLLGTCSPLRLTSPLL HS21_PE783 NOISO G------TSSDSCLTF--SASKSPAGLSG------TP----ATQGLLGACSPVRLASPFL LOXAF67_11_PE8 NOISO G------TSSDSCLTF--SASDSPAGLSS-------L----ATQGLGGACSPVRVAAPCL MACEUGS_5215_PE1 NOISO G------TSSDSCLIS--SSSDGSEGLSS------CL----NDQGPMANSTTVKMTSPFL MACMU3_4_PE8 NOISO G------TSSDSCLTF--SASKSPVGLSG------TP----ATQGLLGACSPVRLASPFL MICMU10143_PE1 NOISO G------ASSDSCLTF--SASDGPAALSG------GL----ASQGLLGTCSPVRLASPFL MONDO4_10_PE20 NOISO G------TSSDSCLTS--SSSNGSGGLSS------CL----NGQVLMADSSDVKLASPFL MOUSE17_PE914 NOISO G------TSSDSCLPF--SASEGPAGLGS------GL----ATPGLLGTSSPVRLASPFL MYOLUGS_2972_PE1 NOISO G------TSSDSCLTF--SAGDSPAGLSG------CL----AAQGLVGTCSPLKLASPLL NEMVE_5053_PE7 NOISO ------------------------------------------------------------ OCHPR24279_PE1 NOISO G------TSSDSCLS---ALSPGPVILGN------GL----APQGLLTTYYPLRLNAPLL ORNANULTRA222_5_PE7 ENSOANG00000006466 G------TSSDSCLPS--SSTEGSGALGG------RL----ADQVLMGNAATVRMASPFL ORNANULTRA222_5_PE8 ISOFORMIN G------TSSDSCLPS--SSTEGSGALGG------RL----ADQVLMGNAATVRMASPFL ORYLA21_6_PE2 NOISO G------ASSDSCLKS--SSSPPPSLQAAIREVSTLQAPDTRNEAPAPTGAPLTLSS--- OTOGA106538_PE1 NOISO G------ASSDSCPTF--SASEGPTGFSG------DL----VTQGLLGTYSPVRLASPFL PANTR21_44_PE11 NOISO G------TSSDSCLTF--SASKSPAGLSG------TP----ATQGLLGACSPVRLASPFL POEGU1_5_PE12 NOISO G------TSSDSCLTS--SSNDSSVALSS------CL----AGQVMTGSPATARMTSPFL POEGUUN_26_PE2 NOISO ------------------------------------------------------------ PONPY21_46_PE1 NOISO G------TSSDSCLTF--SASKSPAGLSG------TP----ATQGLLGACSPVRLASPFL PROCAGS_3809_PE1 NOISO G------TSSDSCLTF--SASDGPMGLSS-------L----ATQGLGGTCSPVRVAAQCL PTEVA15161_PE1 NOISO G------TSSDSCLT---SAGDGPAELSG------RL----GAQGPVGTCFPLRLASPLL RAT20_PE448 NOISO G------TSSDSCLPF--SASEGPAGLGG------GL----ATPGLLGTSSPVRLASPFL SPETRGS_2922_PE1 NOISO G------TSSDSCLTL--SAGESPVGLGS------SL----ATQGLLGTCSPVRLASPFL TETNG2_PE879 NOISO G------ASSDSCLKS--SSSPAASLQGVLGGASGPLASGAGGGALLSAGAPLALSS--- TURTR106893_PE1 NOISO G------TSSDSCLT---SAGDSLAGLSG------HL----VAQGLLSACSPLRLASPLL XENTR1084_PE7 ISOFORMIN SHSRVWLPLPLACLAPTPTRVSG--------PESCRL----PPWVPVPAGPYERCCPAPL XENTR1084_PE8 ENSXETG00000013685 SVGPIMI--------HVPRSPSGPAGFHR--PESCRL----PPWVPVPAGPYERCCPAPL XENTR1084_PE9 ISOFORMIN SHSRVWLPLPLACLAPTPSRVSGPAGFHR--PESCRL----PPWVPVPAGPYERCCPAPL MATCH CONSENSUS G???????SSD?CL????S?????????????????????????????????????????

AILMEGL194603_1_PE1 NOISO GAQSATPVLQAQGVPGGVTLLPISFQEGRRASDTSLTQ--GLKAFRQQLRKNARTKGLLG ANOCA118_1_PE4 NOISO ASHSDTPVLQAQGCLGGASLLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKNARAKGFLG BOVIN1_151_PE19 NOISO GTQSATPMLQAQGALRGAALLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKNARTKG--- CALJA21_49_PE3 NOISO GSQSATPVLQAQGGLGGAVLLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKTARTKGFLG CANFA31_40_PE24 NOISO GAQSATPVLQAQGAPGGVTLLPISFQEGRRASDTSLTQ--GLKAFRQQLRKNARTKGLLG CAOWC1_1_8257 NOISO ------------------------------------------------------------ CAVPO90_4_PE5 NOISO GAQSATPVLQAQGGLGGAVLLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKNARTKGFLG CHICK1_PE1912 NOISO ASQSDAPVLQVQGCMGGASLLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKNARAKGFLG DANRE9_10_PE10 ISOFORMIN ------------------------------------------------------------ DANRE9_10_PE9 ENSDARG00000058606 -----NLLLQNQ-----GSMLAASFQEGRRASDTSLTQ--GLKAFRQQLRKNTRAKGLLG DIPOR24691_PE1 NOISO EAQSATPVLQAQASLGGAVLLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKNARTKGFLG FELCAGS_3190_PE2 NOISO ------------------------------------------------------------ FUGRU42_1_PE71 NOISO -----HLQPQAQ-----GSLPAASFQEGRRASDTSLTQ--GLKAFRQQLRKSTRTKGLLG GASACGROUPXVI_8_PE88 NOISO -----HLLPQGQ-----ACLPAASFQEGRRASDTSLTQ--GLKAFRQQLRKNTRTKGLLG GORGO21_33_PE9 NOISO GSQSATPVLQAQGGLGGAVLLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKTTRTKGFLG HORSE26_39_PE13 NOISO GAQSATPVLQAQEALGGAAPLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKNARTKGFLG HS21_PE783 NOISO GSQSATPVLQAQGGLGGAVLLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKTTRTKGFLG LOXAF67_11_PE8 NOISO GTQSATPVLQAQGGLGCTVPLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKNARTKGFLG MACEUGS_5215_PE1 NOISO VAQSDTPGLKIEGCLGGAALLPVSFQEGRRASDTSLTQ--XXXXXXXXXXXXXXXXXXXX MACMU3_4_PE8 NOISO GSQSATPVLPTQGGLGGAVLLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKTTRTKGFLG MICMU10143_PE1 NOISO GSQSATPVLQAQGDLGGAALLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKTTRTKGFLG MONDO4_10_PE20 NOISO VAQCDTPGQKLEGGLGRAALLPLSFQEGRRASDTSLTQ--GLKAFRQQLRKNTRAKGLLG MOUSE17_PE914 NOISO GSQSATPVLQTQAGLGTAVLPPVSFQEGRRASDTSLTQ--GLKAFRQQLRKNARTKGFLG MYOLUGS_2972_PE1 NOISO GAQSATPVLQAQGALGGAALLPISFQEGRRASDTSLTQ--GLKAFRQQLRKNTRTKGFLG NEMVE_5053_PE7 NOISO ------------------------------------------------------------ OCHPR24279_PE1 NOISO GAQSATPVLQAQGASGGAVLFPLSFQEGRRASDTSLTQ--GLKAFRQQLRRSARTKGFLG ORNANULTRA222_5_PE7 ENSOANG00000006466 TARSTAPVLRAQGCLGGAALLPISFQEGRRASDTSLTQ--GLKAFRQQLRKNARTKGLLG ORNANULTRA222_5_PE8 ISOFORMIN TARSTAPVLRAQGCLGGAALLPISFQEGRRASDTSLTQ--GLKAFRQQLRKNARTKGLLG ORYLA21_6_PE2 NOISO -----HLQPQGQ-----SSLPSASFQEGRRASDTSLTQAPGLKAFRQQLRKNTRTKGLLG OTOGA106538_PE1 NOISO GSQSATPVLQAQGGLGGAALLPVSFQEGRRASDTSLTQ--ALKAFRQQLRKTTRTKGFLG PANTR21_44_PE11 NOISO GSQSATPVLQAQGGLGGAVLLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKTTRTKGFLG POEGU1_5_PE12 NOISO ASQSDAPVLQAQGCMGGASLLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKNARAKGFLG POEGUUN_26_PE2 NOISO ------------------------------------------------------------ PONPY21_46_PE1 NOISO GSQSATPVLQAQGGLGGAVLLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKTTRTKGFLG PROCAGS_3809_PE1 NOISO GAQSATPVLQAQGGLGCTVPLPVSFQEGRRASDTSLTQ--XXXXXXXXXXXXXXXXXXXX PTEVA15161_PE1 NOISO GAQSATPVLQAQGALGGAVLLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKSARTKGFLG RAT20_PE448 NOISO GSQSATPVLQSQAGLGATVLPPVSFQEGRRASDTSLTQ--GLKAFRQQLRKNARTKGFLG SPETRGS_2922_PE1 NOISO GAQSATPMLQAQGGLGRAVLLPVSFQEGRRASDTSLTQ--XXXXXXXXXXXXXXXXXXXX TETNG2_PE879 NOISO -----HLQPQAQ-----GSLPAASFQEGRRASDTSLTQ--GLKAFRQQLRKSTRTKGLLG TURTR106893_PE1 NOISO GTQSATPVLQAQGALGGAALLPVSFQEGRRASDTSLTQ--GLKAFRQQLRKNARTKGFLG XENTR1084_PE7 ISOFORMIN SAQSATPVLQAQGSVAQNGLLPITFQEGRRASDTSLTQ--GAVALR-QLRKSIRVRGLFS XENTR1084_PE8 ENSXETG00000013685 SAQSATPVLQAQGSVAQNGLLPITFQEGRRASDTSLTQ--GAVALR-QLRKSIRVRGLFS XENTR1084_PE9 ISOFORMIN SAQSATPVLQAQGSVAQNGLLPITFQEGRRASDTSLTQ--GAVALR-QLRKSIRVRGLFS MATCH CONSENSUS ???????????Q???????????SFQEGRRASDTSLTQ?????A?R?QLR???R??G???

AILMEGL194603_1_PE1 NOISO LNKIKGLARQVCQPSSSSSRASRGGLSAFQLPAQSPGL--HSSGANSREGRSLLEEVLHQ ANOCA118_1_PE4 NOISO LNKIKGLARQVCQSSS--ARLARNSMGLFQHPQQNACL--GSSSGSSRESRNLLEEVLQQ BOVIN1_151_PE19 NOISO ------------------------------------------------------------ CALJA21_49_PE3 NOISO LNKIKGLARQVCQAPA--SRASRGGLSPFHAPAQSPGP--HSGAASSREGRSLLEEVLEQ CANFA31_40_PE24 NOISO LNKIKGLARQVCQPSS-SSRATRGGLSAFQLPTQSPGL--HGSGPSSREGRSPLEEVLHQ CAOWC1_1_8257 NOISO ------------------------------------------------------------ CAVPO90_4_PE5 NOISO LNKIKGLARQVCQASS--SRASRGGLSSFHAPTPSPSL--QSGGSGGREGRSLLEDVLHQ CHICK1_PE1912 NOISO LNKIKGFARQVCQSSS--SRAARSAMSPFQHAQPNTCI--YSSSGSSREGRNLLEEVLQQ DANRE9_10_PE10 ISOFORMIN ------------------------------------------------------------ DANRE9_10_PE9 ENSDARG00000058606 LNKIKGLARQVCPPSS-CSRGSRGSLGPTMCPPSS-----LQSSSGPRERRSMLEEVLHQ DIPOR24691_PE1 NOISO LNKIKGLARQVCQSSS---RAPRG---ALHAPAQSPSL--QSGSAGGREGRSLLEEVLHQ FELCAGS_3190_PE2 NOISO ------------------------------------------------------------ FUGRU42_1_PE71 NOISO LNKIKGLTRQVVPPPS-CNRGSRGSLGPTLS-----------------EHRSMLEEVLHQ GASACGROUPXVI_8_PE88 NOISO LNKIKGLTRQVFPPLS-STRGSRGAAGPAHC-----------------EHRSMLEEVLHQ GORGO21_33_PE9 NOISO LNKIKGLARQVCQAPA--SRASRGGLSPFHAPAQSPGL--HGGAAGSREGWSLLEEVLEQ HORSE26_39_PE13 NOISO LNKIKGLARQVCQPSS-SSRATRGGLNAFQLPAPSPGL--HGSGASSREGRSLLEEVLHQ HS21_PE783 NOISO LNKIKGLARQVCQAPA--SRASRGGLSPFHAPAQSPGL--HGGAAGSREGWSLLEEVLEQ LOXAF67_11_PE8 NOISO LNKIKGLARQVCQPAS-SSRAPRGGLSPFPLPAQNAGP--YSSGGSGREGRNLLEQVLHQ MACEUGS_5215_PE1 NOISO XXXXXXXXXXXXXXXX--XXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MACMU3_4_PE8 NOISO LNKIKGLARQMCQAPA--SRASRGGLSPFHAPAQSPGL--HGVAAGSREGRSLLEEVLEQ MICMU10143_PE1 NOISO LNKIKGLARQVCQSPS--SRAARGGLSPFHTPAQSPGL--HGGAASGREGRSLLEEVLQQ MONDO4_10_PE20 NOISO LNKINGLARQACQASS--GRATRGCLNSSQHYQPNPCL--YSSGGKGREGENLLEEVLHQ MOUSE17_PE914 NOISO LNKIKGLARQVCQSS---VRTPRGGMSTFHTPAPSSGL--QGCTTSNREGRSLLEEVLHQ MYOLUGS_2972_PE1 NOISO LNKIKGLARQVCQPSS--SRATRGGLSAFQLPAQSPGL--HGSGASSREGRSLLEEVLHQ NEMVE_5053_PE7 NOISO ------------------------------------------------------------ OCHPR24279_PE1 NOISO LNKIKGLARQVCQAST--G----------RTPTQNPGL--QGGPPGGREGRGMLEDVLLQ ORNANULTRA222_5_PE7 ENSOANG00000006466 LNKIKGLARQVCQPAP--ARPPRSIPPAFHHSQQTPGGYGSSSGGCSREGRSLLEEILHQ ORNANULTRA222_5_PE8 ISOFORMIN LNKIKGLARQVCQPAP--ARPPRSIPPAFHHSQQTPGGYGSSSGGCSREGRSLLEEILHQ ORYLA21_6_PE2 NOISO LNKIKGLTRQVVSPPS-CNRGSRGSIGPAFS-----------------EHRSMLEEVLHQ OTOGA106538_PE1 NOISO LNKIKGLARQVCQSPS--SRATRGGLSPFHPPAQSPGL--HSSTASGREGRSLLEEVLQQ PANTR21_44_PE11 NOISO LNKIKGLARQVCQAPA--SRASRGGLSPFHAPAQSPGL--HGGAAGSREGWSLLEEVLEQ POEGU1_5_PE12 NOISO LNKIKGFARQVCQSSS--SRAARSAMSPFQHTQPNTCM--YSSSGSSREGRSLLEEVLQQ POEGUUN_26_PE2 NOISO ------------------------------------------------------------ PONPY21_46_PE1 NOISO LNKIKGLARQVCQAPA--SRASRGGLSPFHTPAQSPGL--HGGAAGSREGWSLLEEVLEQ PROCAGS_3809_PE1 NOISO XXXXXXXXXXXXXXXX----XXX--XXXXXXXXXXXXXXXXPYSSGSDVTRNLLEEVLHQ PTEVA15161_PE1 NOISO LNKLKGLARQVCQCAP--GRAARGGLSAFQLPAQSLGL--HGSGASGREGRGLLEEVLHQ RAT20_PE448 NOISO LNKIKGLARQVCQSS---IRGSRGGMSTFHTPAPSSGL--QGCTASSREGRSLLEEVLHQ SPETRGS_2922_PE1 NOISO XXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXX TETNG2_PE879 NOISO LNKIKGLTRQVVPPSS-CNRGSRGSLGPTLS-----------------EHRSMLEEVLHQ TURTR106893_PE1 NOISO LNKIKGLARQVCQPSS--SRTSRGGLSTFQLPAQSPGL--HGGGAGGREGRSLLEEVLHQ XENTR1084_PE7 ISOFORMIN LSKIRAMNRQ-------------------------------------------------- XENTR1084_PE8 ENSXETG00000013685 LSKIRAMNRQ-------------------------------------------------- XENTR1084_PE9 ISOFORMIN LSKIRAMNRQ-------------------------------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL194603_1_PE1 NOISO QRLLQLQHHPAGLP---SCQQAPQL--PPAPLVLAPCDGALLV----------------- ANOCA118_1_PE4 NOISO QRILQLQHK---QP---ACPQPSQV--SQPHIIPLS-DTAG-SKASN-----SLLL---- BOVIN1_151_PE19 NOISO ------------------------------------------------------------ CALJA21_49_PE3 NOISO QRLLQLQHHPAATP---SCSQAPQP--NPTPFVIAPCDGPGA------------------ CANFA31_40_PE24 NOISO QRLLQLQHHPAGPP---GCQQA-------APLVLAPCDGALLV----------------- CAOWC1_1_8257 NOISO ------------------------------------------------------------ CAVPO90_4_PE5 NOISO QRLLQLQHHPGSPP---SCPQAPQPPPAPAPYVLAPCDGLLV------------------ CHICK1_PE1912 NOISO QRMLQLQHHQLLQP---ACPQTSQT--SATNGLPPS-DSAGTCKASN-----SLLL---- DANRE9_10_PE10 ISOFORMIN ------------------------------------------------------------ DANRE9_10_PE9 ENSDARG00000058606 QRMLQIQHQPQPQVQ------F------------LSQSHPSSPPSNNLFAPAALFSNPPT DIPOR24691_PE1 NOISO QRLLQLQHHPATPP---GCQQA--LPQPPAPYALAPCDGLLA------------------ FELCAGS_3190_PE2 NOISO ------------------------------------------------------------ FUGRU42_1_PE71 NOISO QRLLQIQHQSQPQVQ------APQPGPAQNPLLFRAQHQPPSPPS-SVFASSAMFDNSS- GASACGROUPXVI_8_PE88 NOISO QRMLQIQHQPQPQQA------S-------------------------------------- GORGO21_33_PE9 NOISO QRLLQLQHHPAAAP---GCSQAPQP--APAPFVIAPCDGPGA------------------ HORSE26_39_PE13 NOISO QRLLQLQHHPAAPP---TCQQA--------PLVLGPCDGALL------------------ HS21_PE783 NOISO QRLLQLQHHPAAAP---GCSQAPQP--APAPFVIAPCDGPGA------------------ LOXAF67_11_PE8 NOISO QRLLQLQHHPAAQP---SCSQAPPL--PQAPYVLAPCDGSGVPPLSS-----TLLV---- MACEUGS_5215_PE1 NOISO XXLLQLQHSTSVPL---SCPQAPQL--PSAQYVIST--CDETYQTPN-----SLLS---- MACMU3_4_PE8 NOISO QRLLQLQHHPAAAP---GCSQAAQP--APAQFVIAPCDGPGA------------------ MICMU10143_PE1 NOISO QRLLQLQHHPATPP---PCQQAPQ------AYALGPCDGPGA------------------ MONDO4_10_PE20 NOISO QRLLQLQHNTSVHL---SCPQAPQL--SQAQYVISA--CDESYPEAN-----PLLT---- MOUSE17_PE914 NOISO QRLLQLQHHSSTAAASSGCQQG--PQLSPVPYVLAPCDSLLV------------------ MYOLUGS_2972_PE1 NOISO QWSWP----PV------------------TALLVGTPEGPG------------------- NEMVE_5053_PE7 NOISO ------------------------------------------------------------ OCHPR24279_PE1 NOISO QRLLQLQHRPATPP---SCLQVPQL--ATAPCLLPPT---------N-----SLL----- ORNANULTRA222_5_PE7 ENSOANG00000006466 QRLLQWQHKPQAPA---GIPPGP---------QPPP-PTPGGPWAPG-----SLLL---- ORNANULTRA222_5_PE8 ISOFORMIN QRLLQWQHKPQAPA---GIPPGP---------QPPP-PTPGGPWAPG-----SLLL---- ORYLA21_6_PE2 NOISO QRMLQIQHQPQPHVQ------AAPTGPTPNPLLFLTQQKSPSLPSTAMFASSSLFDAPGQ OTOGA106538_PE1 NOISO QRLLQLQHHPAALH---TCQQAPQ------P-MLGPCDGSGA------------------ PANTR21_44_PE11 NOISO QRLLQLQHHPAAAP---GCSQAPQP--APAPFVITPCDGPGA------------------ POEGU1_5_PE12 NOISO QRMLQFQHHQLLQT---ACPHSH-T--PAASSFPSS-DGPGTCKASN-----SILL---- POEGUUN_26_PE2 NOISO ------------------------------------------------------------ PONPY21_46_PE1 NOISO QRLLQLQHHPAAAP---GCSQAPQP--APAPFVIAPCDGPGA------------------ PROCAGS_3809_PE1 NOISO QRLLQLQHHPAAQP---SCPQAPPV--PQAPYVLTPCDSPSGTTLSN-----TLLA---- PTEVA15161_PE1 NOISO QRLLQLQHHPAAPP---SCPQAA--PPPPAPLLLAPGDGALLV----------------- RAT20_PE448 NOISO QRLLQLQHHSAV---SSDYQQA--PQLSPVPYVLTPCDGLLV------------------ SPETRGS_2922_PE1 NOISO XXLLQLQHHPTAPP---SCQQAP--PLPPTSYVLAPCDSALV------------------ TETNG2_PE879 NOISO QRLLQIQHQSQPPVQ------APQPGPAQNPLLFRTRSCSSAAQP--------------- TURTR106893_PE1 NOISO QRLLQLQHHPAAPP---GCQPAAQP--PPAPLVLAPCDGALLV----------------- XENTR1084_PE7 ISOFORMIN ------------------------------------------------------------ XENTR1084_PE8 ENSXETG00000013685 ------------------------------------------------------------ XENTR1084_PE9 ISOFORMIN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL194603_1_PE1 NOISO -----------SGLQK-EL-----GLGPSPLLPPHLLQAGGSPVASAAQLLDTHLHISHA ANOCA118_1_PE4 NOISO -----------TELQS-ENSLELAFHN-TQFLQPHLFGVGVSPVNSTAHLLDTRLHISN- BOVIN1_151_PE19 NOISO ------------------------------------------------------------ CALJA21_49_PE3 NOISO -----------TLLPS-TL-----FTSGLPLLPPPLLQAGVSPVTSAAQLLDTQLHIGAS CANFA31_40_PE24 NOISO -----------SGLQK-EL-----GLGPGPLLPPHLLHAGGSPVASAARLLDTHLHISHT CAOWC1_1_8257 NOISO ------------------------------------------------------------ CAVPO90_4_PE5 NOISO -----------SG---------------LPLLPAPLLHSGTSPVTSTAQLLDTQLHISSS CHICK1_PE1912 NOISO -----------SELQR-ENSFELAFGGNSQLLQPHFFGVSVSPVSSAAHLLDTHLYISS- DANRE9_10_PE10 ISOFORMIN ------------------------------------------------------------ DANRE9_10_PE9 ENSDARG00000058606 QAILPPCQKTSIAFQHNLWQQQQSF---------DSSSSSLSPVASAAHLLEARLHISQR DIPOR24691_PE1 NOISO -----------SG---------------LTLLPAPLLPAGVSPVASAARLLDAHLRISAE FELCAGS_3190_PE2 NOISO ------------------------------------------------------------ FUGRU42_1_PE71 NOISO ------------------------------ILPPHCFSSSLSPVASAAYLLEARLHI--- GASACGROUPXVI_8_PE88 NOISO -----------LGLSHVAWKTLKTSSSGGSSSPSCCYASSLSPVASAAYLLEARLHIS-- GORGO21_33_PE9 NOISO -----------APLPS-TI-----LMSGLPLLPPPLLQTGVSPVASAAQLLDTHLHIGTG HORSE26_39_PE13 NOISO ---------------K-GL-----GLGPGPLLPPHLLQAGASPVASAAQLLDAHLRISRT HS21_PE783 NOISO -----------APLPS-TL-----LTSGLPLLPPPLLQTGASPVASAAQLLDTHLHIGTG LOXAF67_11_PE8 NOISO -----------SGLQK-ELV-----LGPSPLLPPHLFPAAASPAASAAQLLDTHLHISST MACEUGS_5215_PE1 NOISO ---------------------------SELLLAPSPLQTSVSPVSSATQLLDSHLYINSN MACMU3_4_PE8 NOISO -----------APLPS-TL-----LMSGLPLLQPPLLQTGVSPVASAAQLLDTHLHIGAG MICMU10143_PE1 NOISO -----------APLPS-AL-----LAAGLPLLPAPLLQASVSPVASAARLLDAHLHISAG MONDO4_10_PE20 NOISO -----------------------------CGAHPHLFKGSVSPVSSAAQLLDSPLGIHSH MOUSE17_PE914 NOISO -----------SG---------------IPLLPTPLLQAGMSPVASAAHLLDTHLHISAG MYOLUGS_2972_PE1 NOISO --------------------------AGLPLLPPHLLQAGVSPVASAAHLLDTHLHISTA NEMVE_5053_PE7 NOISO ------------------------------------------------------------ OCHPR24279_PE1 NOISO -------------------------------VPGIPLLPALSPVASAARLLDTQLHIGPS ORNANULTRA222_5_PE7 ENSOANG00000006466 -----------SELQR-ENSLELALRPAQP-PLPPPFGTGVSPASSAAQLLDAHLDLRAD ORNANULTRA222_5_PE8 ISOFORMIN -----------SEL---------------P-PLPPPFGTGVSPASSAAQLLDAHLDLRAD ORYLA21_6_PE2 NOISO HSQ--PPQPASGGLQHSPWHQTLET---------SFSGSSLSPVASAAYLLEARLHISQQ OTOGA106538_PE1 NOISO -----------TPLPS-AL-----LTAGLPLLPPPLLQASISPVASAARLLDTHLHISAR PANTR21_44_PE11 NOISO -----------APLPS-TL-----LMSGLPLLPPPLLQTGVSPVASAAQLLDTHLHIGTG POEGU1_5_PE12 NOISO -----------SELQR-ENSFELAFAGSSQLLQPHFFGVSVSPVSSAAHLLDTQLYISGG POEGUUN_26_PE2 NOISO ------------------------------------------------------------ PONPY21_46_PE1 NOISO -----------APLPS-TL-----LMSGLPLLPPPLLQTGVSPVASAAQLLDTHLHIGAG PROCAGS_3809_PE1 NOISO -----------SG---------------LPLLPPHLFPAAASPAASAAQLLDTHLHISSS PTEVA15161_PE1 NOISO -----------SG---------------LPLLPPRLLQAGVSPVASAAQLLDTHLRISAA RAT20_PE448 NOISO -----------SG---------------IPLLPTPLLQPGMSPVASAAQLLDAHLHISAG SPETRGS_2922_PE1 NOISO --------------------------SGLPLLPAPLFQAGVSPVMSTARLLDAHLHISAG TETNG2_PE879 NOISO ------------------------------LATSPGQLSSLSPVASAAYLLEARLHIS-- TURTR106893_PE1 NOISO -----------SGLL---------------LLPPPLLQAGGSHVASAAQLLDAHLRISSS XENTR1084_PE7 ISOFORMIN ------------------------------------------------------------ XENTR1084_PE8 ENSXETG00000013685 ------------------------------------------------------------ XENTR1084_PE9 ISOFORMIN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL194603_1_PE1 NOISO TA--PHPAA----------------TLPPSFVAAGL-PQADCEMEDLT-----AGQLGTF ANOCA118_1_PE4 NOISO -NVSPIASMF-------SQQNGFA-LQSQSYNAVAL-QHGDCEMEDLT-----STQMGKF BOVIN1_151_PE19 NOISO ------------------------------------------------------------ CALJA21_49_PE3 NOISO PT--ALPAA--------P-LPRPA-RLAPGCEPLGL-LQGDFEMEDLS-----PCPLGTF CANFA31_40_PE24 NOISO VA--PRPAA----------------TLPPGFVATGL-PQGDCEMEDLT-----AGQLGTF CAOWC1_1_8257 NOISO ------------------------------------------------------------ CAVPO90_4_PE5 NOISO PA--TLLPG--------ALAPCFA-RLAPGCDPSGR-LQGDCEMEDLT-----SGQRGTF CHICK1_PE1912 NOISO -NVSPVGTAF-------SQQQSFS-AQSPSYDAVTL-QHGDCEMEDLT-----SNQLGKF DANRE9_10_PE10 ISOFORMIN ------------------------------------------------------------ DANRE9_10_PE9 ENSDARG00000058606 SHLHPQSPQHLQIQPNLPSQGPFSLLPHPGSWSLSTSTEPEPNVQELIC-ASQKQQLSNC DIPOR24691_PE1 NOISO QA--PLPAR--------PLQQCL----------AGR-PQGDCEMEDLA-----PSPRGTA FELCAGS_3190_PE2 NOISO ------------------------------------------------------------ FUGRU42_1_PE71 NOISO ------------------------------------------------------------ GASACGROUPXVI_8_PE88 NOISO ------------------------------------------------------------ GORGO21_33_PE9 NOISO ST--ALPAV--------P-PPRLA-RLAPGCEPLGL-LQGDCEMEDLM-----PCSLGTF HORSE26_39_PE13 NOISO SA--PLPAAT-------PPQPPFT-MLPPRFDPTGL-PQGDCEMEDLT-----SGQLGTF HS21_PE783 NOISO PT--ALPAV--------P-PPRLA-RLAPGCEPLGL-LQGDCEMEDLM-----PCSLGTF LOXAF67_11_PE8 NOISO AA--SLASAA-------TPQPCFA-VLPPNFEPAGL-VQGDCEMEDLT-----AGQVGTF MACEUGS_5215_PE1 NOISO T--SPVTAFL-------PTLA----IWSPSCDPAVL-QQGDCEMEDLT-----STQLRKF MACMU3_4_PE8 NOISO PT--TLPAA--------P-PPRLA-RLAPGCEPLGL-LQGDCEMEDLT-----PCPLGTF MICMU10143_PE1 NOISO PV--ALPAA--------PPLPRLA-VLAPGCDPTGL-PRGDCEMEDLT-----AGQRGTF MONDO4_10_PE20 NOISO P--SLATPSF-------PQQPHFA-IWSPSYDPAVL-HQGDYEMEDLT-----SPQVGKF MOUSE17_PE914 NOISO PV--ALPTG--------PLPQCLT-RLSPGCDPAGL-PQGDCEMEDLT-----SGQRGTF MYOLUGS_2972_PE1 NOISO TA--PLPAAT-------PLQPHFA-MLPSGFDPMGL-PQGDCEMEDLT-----SGQLGTF NEMVE_5053_PE7 NOISO ------------------------------------------------------------ OCHPR24279_PE1 NOISO PAV--------------------LARLAPTCEPMEL-PRGACEMRDLP-----SSQLATF ORNANULTRA222_5_PE7 ENSOANG00000006466 AP-PSVTPSF-------PARASIALRPPGGYGPAVL-SQGDCEMEDLT-----PAPLGKF ORNANULTRA222_5_PE8 ISOFORMIN AP-PSVTPSF-------PARASIALRPPGGYGPAVL-SQGDCEMEDLT-----PAPLGKF ORYLA21_6_PE2 NOISO PRPYPFSSFQQ------PQSAPPLVPSKTVLWPTGSG--TDPNMQELAGLTGQQQQLSSC OTOGA106538_PE1 NOISO PT--ALPTM--------PPPPHLA-MLAPGYDPTGL-PQGDCEMEDLT-----SCQLGTF PANTR21_44_PE11 NOISO PT--ALPAV--------P-PPRLA-RLAPGCEPLGL-LQGDCEMEDLM-----PCSLGTF POEGU1_5_PE12 NOISO GGVPPLAASF-------SQQQSFS-TPSPSYDGVTL-QHGDCEMEDLT-----SSQLGKF POEGUUN_26_PE2 NOISO ------------------------------------------------------------ PONPY21_46_PE1 NOISO PT--ALPAV--------P-PPRLA-RLAPGCEPLGL-LQGDCEMEDLT-----PCPLGTF PROCAGS_3809_PE1 NOISO STA------G-------PPPPRFA-VLPPGFEPAGL-VQGDCEMEDLT-----AGQRGTF PTEVA15161_PE1 NOISO SA--PLPAAT-------PLQPHFA-MLPLVFDPMGL-PQGDCEMEDLT-----SGQLGTF RAT20_PE448 NOISO PV--ALPTG--------PLPQCLT-RLSPSCDPAGL-PQGDCEMEDLT-----SGQRGTF SPETRGS_2922_PE1 NOISO PA--VLPTG--------SLPPCLS-RLAPGCDPAGL-PQGNCEMEDLT-----SGQRGTF TETNG2_PE879 NOISO ------------------------------------------------------------ TURTR106893_PE1 NOISO TA--PGPAAV-------APQPCFA-TLSPSLEPAGL-PQGDCEMEDLT-----SGPPGTF XENTR1084_PE7 ISOFORMIN ------------------------------------------------------------ XENTR1084_PE8 ENSXETG00000013685 ------------------------------------------------------------ XENTR1084_PE9 ISOFORMIN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL194603_1_PE1 NOISO VLVQ ANOCA118_1_PE4 NOISO VLVK BOVIN1_151_PE19 NOISO ---- CALJA21_49_PE3 NOISO VLVQ CANFA31_40_PE24 NOISO VLVQ CAOWC1_1_8257 NOISO ---- CAVPO90_4_PE5 NOISO VLVQ CHICK1_PE1912 NOISO VLVK DANRE9_10_PE10 ISOFORMIN ---- DANRE9_10_PE9 ENSDARG00000058606 VMVK DIPOR24691_PE1 NOISO VLVQ FELCAGS_3190_PE2 NOISO ---- FUGRU42_1_PE71 NOISO ---- GASACGROUPXVI_8_PE88 NOISO ---- GORGO21_33_PE9 NOISO VLVQ HORSE26_39_PE13 NOISO VLVQ HS21_PE783 NOISO VLVQ LOXAF67_11_PE8 NOISO VLVQ MACEUGS_5215_PE1 NOISO VLVQ MACMU3_4_PE8 NOISO VLVQ MICMU10143_PE1 NOISO VLVQ MONDO4_10_PE20 NOISO VLVQ MOUSE17_PE914 NOISO VLVQ MYOLUGS_2972_PE1 NOISO VLVQ NEMVE_5053_PE7 NOISO ---- OCHPR24279_PE1 NOISO VLVQ ORNANULTRA222_5_PE7 ENSOANG00000006466 VLVQ ORNANULTRA222_5_PE8 ISOFORMIN VLVQ ORYLA21_6_PE2 NOISO VMVK OTOGA106538_PE1 NOISO VLVQ PANTR21_44_PE11 NOISO VLVQ POEGU1_5_PE12 NOISO VLVK POEGUUN_26_PE2 NOISO ---- PONPY21_46_PE1 NOISO VLVQ PROCAGS_3809_PE1 NOISO VLVQ PTEVA15161_PE1 NOISO VLVQ RAT20_PE448 NOISO VLVQ SPETRGS_2922_PE1 NOISO VLVQ TETNG2_PE879 NOISO ---- TURTR106893_PE1 NOISO VLVQ XENTR1084_PE7 ISOFORMIN ---- XENTR1084_PE8 ENSXETG00000013685 ---- XENTR1084_PE9 ISOFORMIN ---- MATCH CONSENSUS ????


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