Alignment of the gene Family HOG000170931 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
ASFUM1_4_PE267 ASFUM1_4_PE267 ------------------------------------------------------------ ASHGO_3_PE455 ASHGO_3_PE455 ------------------------------------------------------------ ASPCL_57_PE106 ASPCL_57_PE106 ------------------------------------------------------------ ASPFC_10_PE100 ASPFC_10_PE100 ------------------------------------------------------------ ASPFL_5_PE357 ASPFL_5_PE357 ------------------------------------------------------------ ASPNC_10_PE105 ASPNC_10_PE105 ------------------------------------------------------------ ASPNG_1_PE630 ASPNG_1_PE630 ------------------------------------------------------------ ASPOR_10_PE292 ASPOR_10_PE292 ------------------------------------------------------------ ASPTE_20_PE313 ASPTE_20_PE313 ------------------------------------------------------------ CANAW_2_PE426 CANAW_2_PE426 AYNNNNNSS--------------------------------------------NYNYNFN CANDC_2_PE425 CANDC_2_PE425 AYNNNNNSA--------------------------------------------NYNYNFN DEHAN1_4_PE349 DEHAN1_4_PE349 --------M--------------------------------------------SYNFNYN EMENI_36_PE362 EMENI_36_PE362 ------------------------------------------------------------ KLLAC1_2_PE244 KLLAC1_2_PE244 ------------------------------------------------------------ LACTH_6_PE229 LACTH_6_PE229 ------------------------------------------------------------ NEFIS1_277_PE105 NEFIS1_277_PE105 ------------------------------------------------------------ NEUCR_187_PE19 NEUCR_187_PE19 ACPNQRPESIVFESFKPSLSFPPLAPTTPPATATEFIAKPDPATAPS-----PSRELAFA PENCW_10_PE703 PENCW_10_PE703 ------------------------------------------------------------ PHATR_26_PE12 PHATR_26_PE12 ------------------------------------------------------------ PICPG_2_PE1224 PICPG_2_PE1224 ------------------------------------------------------------ PISTI1_4_PE509 PISTI1_4_PE509 ------------------------------------------------------AYNNFN YALIP1_4_PE623 YALIP1_4_PE623 -----------------------------------MDHSPSP----------------HH YEASTX_PE89 YEASTX_PE89 NSSNNNDSSS---------------------SNSNMNNSLSPTLVTHSDASMGSGRASPD ZYGRO_4_PE119 ZYGRO_4_PE119 ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

ASFUM1_4_PE267 ASFUM1_4_PE267 ----MGSQWQPYQDPLMGRPAQFNNG-LAS--TPQQLGPKYGGQPQQSQPPV--GYTYEA ASHGO_3_PE455 ASHGO_3_PE455 MKEERKSIWNPAFDMSAG-----------------A------------------------ ASPCL_57_PE106 ASPCL_57_PE106 ----MGSQWQPYQDPLMGQPAQFNNG-LAS--TPQQLAPKYGGQPQQSQPPV--GYTYEA ASPFC_10_PE100 ASPFC_10_PE100 ----MGSQWQPYQDPLMGRPAQFNNG-LAS--TPQQLGPKYGGQPQQSQPPV--GYTYEA ASPFL_5_PE357 ASPFL_5_PE357 ----MDSQWQPYQDPLMGRPAQLNNG-LTS--NPPQLGPKYGGQPQQSQPPV--GYTYEA ASPNC_10_PE105 ASPNC_10_PE105 ----MDSQWQAYQDPLMGHPAQFNNG-LTS--NPQQLASKYGAQPQHSQPPV--GYTYEP ASPNG_1_PE630 ASPNG_1_PE630 ----MDSQWQAYQDPLMGHPAQFNNG-LTS--NPQQLASKYGAQPQHSQPPV--GYTYEP ASPOR_10_PE292 ASPOR_10_PE292 ----MDSQWQPYQDPLMGRPAQLNNG-LTS--NPPQLGPKYGGQPQQSQPPV--GYTYEA ASPTE_20_PE313 ASPTE_20_PE313 ----MDSQWQPYQDHMMGGRPVQQ-F-NHA--PPQQLPSKYGAQPQQAQPPV--GYTYET CANAW_2_PE426 CANAW_2_PE426 RHNSIGGNWHLPPPPPPPTQPT-----------SSGAYHQQQ-QQQHSQQHLSP------ CANDC_2_PE425 CANDC_2_PE425 RHNSIGGSWHLPPPPPPQPQPP-----------STGAYQ----------QHLSP------ DEHAN1_4_PE349 DEHAN1_4_PE349 RHNSLGGNWQLPPPYGLNGSEQ--------------------------TPPLAD------ EMENI_36_PE362 EMENI_36_PE362 ----MNSQWQPYKDPLVGRPAQFNNNGLTSNPNTQQLPSNYGGQSQSSQAPA--GYTYEP KLLAC1_2_PE244 KLLAC1_2_PE244 -MGDKNSLWNPAFMASQQ-----------------GASSSNQNQNFSQTQANT-QNQG-- LACTH_6_PE229 LACTH_6_PE229 MPESDKSIWNPAFLNNAQ-----------------K------------------------ NEFIS1_277_PE105 NEFIS1_277_PE105 ----MGSQWQPYQDPLMGRPAQFNNG-LAS--TPQQLGPKYGGQPQQSQPPV--GYTYEA NEUCR_187_PE19 NEUCR_187_PE19 LPAAMEQQWQPYSDSAASGSSRRYNNGSGQMSMSPRDYASNGQVQAQQQPLA--GYKYDP PENCW_10_PE703 PENCW_10_PE703 ----MDPGWQPYQDPLMGHPAQFNTA---LASHPQQLASKYG-QPPQSQPPV--GYTYET PHATR_26_PE12 PHATR_26_PE12 ------------------------------------------------------------ PICPG_2_PE1224 PICPG_2_PE1224 ------------------------------------------------------------ PISTI1_4_PE509 PISTI1_4_PE509 RHNSIGGNWHLPPPPHGYNSMN-----------MNN-F----------NNPINS------ YALIP1_4_PE623 YALIP1_4_PE623 RKMSSNGHLMPSLIGHKQ-----------------QQQHQQQQQQQQQQPPYPTDYYRKS YEASTX_PE89 YEASTX_PE89 NSHMGRGIWNPSYVNQGS-----------------QRSPQQQHQNHHQQQQQ-------- ZYGRO_4_PE119 ZYGRO_4_PE119 -------MWNPLYLSSED-----------------QEQLKKQQQQQGLQQRLH-QMER-- MATCH CONSENSUS ????????W???????????????????????????????????????????????????

ASFUM1_4_PE267 ASFUM1_4_PE267 FQTPGTAAKPPS-AGANSKSVSMASSPAATPRSRDYVTDADTTMED-------------- ASHGO_3_PE455 ASHGO_3_PE455 -----------------------------------------AKTGKVLG--------RQS ASPCL_57_PE106 ASPCL_57_PE106 FQTPGIAAKPPS-AGANSKSVSMASSPAATPRSRDYVTDADTTMED-------------- ASPFC_10_PE100 ASPFC_10_PE100 FQTPGTAAKPPS-AGANSKSVSMASSPAATPRSRDYVTDADTTMED-------------- ASPFL_5_PE357 ASPFL_5_PE357 FQTPGIAAKPAS-TGMNSKSVSMASSPAATPRSRDYVTDADTTMED-------------- ASPNC_10_PE105 ASPNC_10_PE105 FQSPGTTAKPPS-IGANSRTVSMASSPAATPRSRDYVTDADTTMED-------------- ASPNG_1_PE630 ASPNG_1_PE630 FQSPGTTAKPPS-IGANSRTVSMASSPAATPRSRDYVTDADTTMED-------------- ASPOR_10_PE292 ASPOR_10_PE292 FQTPGIAAKPAS-TGMNSKSVSMASSPAATPRSRDYVTDADTTMED-------------- ASPTE_20_PE313 ASPTE_20_PE313 FQTPAIAPQPPS-LGNNSKSVSMASSPAATPRSRDYVTDADTTMED-------------- CANAW_2_PE426 CANAW_2_PE426 ----------------------------NHPNGQDILSS-----SDSQFSSQLKQNQIPG CANDC_2_PE425 CANDC_2_PE425 ----------------------------NNPNGQDILS------SDSQFSPQLKSNQIPG DEHAN1_4_PE349 DEHAN1_4_PE349 ----------------------------NTPGV-------------QDPQRTAQSNQMPG EMENI_36_PE362 EMENI_36_PE362 FQSPGIIAKPPS-T----KSASMASSPAATPHTRDYVTEQDAIMED-------------- KLLAC1_2_PE244 KLLAC1_2_PE244 PEIAPDGPAGSSSNA------G----------GNIYAGQ--QQGGNAAGGFQMQSPRQSI LACTH_6_PE229 LACTH_6_PE229 -----------------------------------------QQG---AP--------SYG NEFIS1_277_PE105 NEFIS1_277_PE105 FQTPGTAAKPPS-AGANSKSVSMASSPAATPRSRDYVTDADTTMED-------------- NEUCR_187_PE19 NEUCR_187_PE19 YQAGLNPSAQPQ-SS----S----ISPMTSSQSRDA--NGDVAMQDA------------- PENCW_10_PE703 PENCW_10_PE703 FQTPGTTSKAPS-AGSNSKTVSMASSPTATPRTRDYVTDADTTMED-------------- PHATR_26_PE12 PHATR_26_PE12 ------------------------------------------------------------ PICPG_2_PE1224 PICPG_2_PE1224 --------------------------------------------------------MSFN PISTI1_4_PE509 PISTI1_4_PE509 ----------------------------NNQNQQ----R-----KQQTQQNQLSNQHMSG YALIP1_4_PE623 YALIP1_4_PE623 FESAPNVSASSSAAAASSTSAGMGSPHMSHSQRSLYYHQ--QQMGPFSP-SQPHPQFQTS YEASTX_PE89 YEASTX_PE89 ------------------------------------------------QQQQQQQNSQFC ZYGRO_4_PE119 ZYGRO_4_PE119 RQ--------SQS-----------------------QRA--QHQQHSQQHQQPQQQVQFT MATCH CONSENSUS ????????????????????????????????????????????????????????????

ASFUM1_4_PE267 ASFUM1_4_PE267 -ADPYN---------------RAKYS------ARP--------------NHH---SRPSS ASHGO_3_PE455 ASHGO_3_PE455 FRNPWGEPGSPAG----RRQS-------------G------------------------- ASPCL_57_PE106 ASPCL_57_PE106 -ADPYN---------------RAKYS------TRP--------------NHH---SRPSS ASPFC_10_PE100 ASPFC_10_PE100 -ADPYN---------------RAKYS------ARP--------------NHH---SRPSS ASPFL_5_PE357 ASPFL_5_PE357 -ADPYN---------------RAKYS------ARP--------------SHH---SRPSS ASPNC_10_PE105 ASPNC_10_PE105 -ADPYN---------------RAKYS------TRP--------------SHH---SRPSS ASPNG_1_PE630 ASPNG_1_PE630 -ADPYN---------------RAKYS------TRP--------------SHH---SRPSS ASPOR_10_PE292 ASPOR_10_PE292 -ADPYN---------------RAKYS------ARP--------------SHH---SRPSS ASPTE_20_PE313 ASPTE_20_PE313 -ADPYN---------------RAKYS------TRP--------------NQH---SRPSS CANAW_2_PE426 CANAW_2_PE426 FRNPWFSQQQNSTPNMLSSSS-SASSSLSQSPTK------SHQIPLLQQHQPPLLNKRLS CANDC_2_PE425 CANDC_2_PE425 FRNPWFSQQQNATPNMLSSSSSSTSTSLSQSPTK------SHQIPLLQQHQPPLLNKRLS DEHAN1_4_PE349 DEHAN1_4_PE349 FRNPWYTSNQAPSGMVT-------SPNMSQSPT-----KGQQTIPLL-QQQ----SKRMS EMENI_36_PE362 EMENI_36_PE362 -ADPYN---------------RAKYP------TRS--------------NHQ---SRPSS KLLAC1_2_PE244 KLLAC1_2_PE244 FKNPWQEIPQIPE----SQRSTM----------RK------------------------Q LACTH_6_PE229 LACTH_6_PE229 FKNPWHDVSGATG----KRNS-------------M------------------------Q NEFIS1_277_PE105 NEFIS1_277_PE105 -ADPYN---------------RAKYS------ARP--------------NHH---SRPSS NEUCR_187_PE19 NEUCR_187_PE19 -HDPYSSQN-----------PTIKYP------LRP--------------HHSLSGGRPAS PENCW_10_PE703 PENCW_10_PE703 -ADPYN---------------RAKYP------SRP--------------NHN---RASSQ PHATR_26_PE12 PHATR_26_PE12 ------------------------------------------------------------ PICPG_2_PE1224 PICPG_2_PE1224 DRQGWKQRAQS------------------------------------------------- PISTI1_4_PE509 PISTI1_4_PE509 FRNPWYSPSQPSSGAGL-------V--LSQSPTKPSLSGAVSAIPLLQQQQ----NKRAS YALIP1_4_PE623 YALIP1_4_PE623 MSNALSTQQLPHPQLMHQYEPSSPVST-----RRP--------------SHEPSHYPPTQ YEASTX_PE89 YEASTX_PE89 FVNPWNEEKVTNS----Q------------------------------------------ ZYGRO_4_PE119 ZYGRO_4_PE119 FTNPWGNNEDLDP----YYSSSA----------GA----------------SSTGLDTSE MATCH CONSENSUS ???P????????????????????????????????????????????????????????

ASFUM1_4_PE267 ASFUM1_4_PE267 QF------------FSPEESS-AAR---------RYSP----MNVLSPSMSYN------- ASHGO_3_PE455 ASHGO_3_PE455 F-QQLATTFEEGQ-----GEEERAR---------R-----RSSLIVPPTRAAGP------ ASPCL_57_PE106 ASPCL_57_PE106 QF------------FSPEESS-AAR---------RYSP----MNALSPAMSYS------- ASPFC_10_PE100 ASPFC_10_PE100 QF------------FSPEESS-AAR---------RYSP----MNVLSPSMSYN------- ASPFL_5_PE357 ASPFL_5_PE357 QY------------FPTEESS-AAR---------RYSP----MNVLSPSMPYN------- ASPNC_10_PE105 ASPNC_10_PE105 QY------------FPSEESS-AAR---------RYSP----MNVLSPSMSFN------- ASPNG_1_PE630 ASPNG_1_PE630 QY------------FPSEESS-AAR---------RYSP----MNVLSPSMSFN------- ASPOR_10_PE292 ASPOR_10_PE292 QY------------FPTEESS-AAR---------RYSP----MNVLSPSMPYN------- ASPTE_20_PE313 ASPTE_20_PE313 QF------------FPQEESS-AAR---------RYSP----MNVLSPSMPYNP------ CANAW_2_PE426 CANAW_2_PE426 FTNNLPITYEHESSSNSSSNNNNNSSSSNGNNNNNDNNTNVPPYIHPPTRADNPFNHYFA CANDC_2_PE425 CANDC_2_PE425 FTNNLPITYEHESTSNNNNNNNNNNNNNNNNDNGNNGNNNVPPYIHPPTRADNPFNHYFA DEHAN1_4_PE349 DEHAN1_4_PE349 FANQLPTTYEYDGQR----------------------PSNAPPFIHPPTRVDNPFNQYYT EMENI_36_PE362 EMENI_36_PE362 QY------------FPSEGST-AAR---------RYSP----MNVLSPTLPYN------- KLLAC1_2_PE244 KLLAC1_2_PE244 SNFPLPTTYEEDNAVD-ESSQQFRR---------R-----NSSLVIPPARAAGP------ LACTH_6_PE229 LACTH_6_PE229 FNQHLPTTYEEAPQHGSASENGFRR---------R-----NSSLIVPPPRAAGP------ NEFIS1_277_PE105 NEFIS1_277_PE105 QF------------FSPEESS-AAR---------RYSP----MNVLSPSLSYN------- NEUCR_187_PE19 NEUCR_187_PE19 LS------------TSQEPSA-AAQ---------RYSP----MEALSPASQYPK------ PENCW_10_PE703 PENCW_10_PE703 FL------------NQAEESS-AAR---------RYSP----GNVLSPPMSYP------- PHATR_26_PE12 PHATR_26_PE12 ------------------------------------------------------------ PICPG_2_PE1224 PICPG_2_PE1224 ---------------SNQGDPAFKN---------VFSVCSTGSYNIPNNGSQIPVRGFQE PISTI1_4_PE509 PISTI1_4_PE509 FANQLPTTYEYDDQR---------------------RQSNAIPFIDPPTRADNPFNQYFT YALIP1_4_PE623 YALIP1_4_PE623 TQYGLPPGLQHQQ-HSS-PHEPLYR---------S-----QPGTPLAPQMQPGTPLGSVQ YEASTX_PE89 YEASTX_PE89 QNLVYPPQYDDLN--SNESLDAYRR---------R-----KSSLVVPPARAPAP------ ZYGRO_4_PE119 ZYGRO_4_PE119 TNPLLAAEY------GGDGFD-TYR---------R-----KSSLVIPPARAPNP------ MATCH CONSENSUS ???????????????????????????????????????????????P????????????

ASFUM1_4_PE267 ASFUM1_4_PE267 ---------------TSPGKSQNSYAFPPGP----------------------------- ASHGO_3_PE455 ASHGO_3_PE455 --------------EPLLRETYGD----SW------G----------------------- ASPCL_57_PE106 ASPCL_57_PE106 ---------------TSPGKSQNSYAFPPGP----------------------------- ASPFC_10_PE100 ASPFC_10_PE100 ---------------TSPGKSQNSYAFPPGP----------------------------- ASPFL_5_PE357 ASPFL_5_PE357 ---------------TSPGKPHNAYAFPPGP----------------------------- ASPNC_10_PE105 ASPNC_10_PE105 ---------------ASPGKSHNSYAFPPGP----------------------------- ASPNG_1_PE630 ASPNG_1_PE630 ---------------ASPGKSHNSYAFPPGP----------------------------- ASPOR_10_PE292 ASPOR_10_PE292 ---------------TSPGKPHNAYAFPPGP----------------------------- ASPTE_20_PE313 ASPTE_20_PE313 ---------------TSPGKSQAPYAFPPGP----------------------------- CANAW_2_PE426 CANAW_2_PE426 TQEVTLGSNDRRMSAAVDGTHYNPYGFNQ-QLNAYPSGPAGIAGTQYLN----NPNLG-- CANDC_2_PE425 CANDC_2_PE425 NQEVTLSNNDRRMSAAVDGTHYNPYGFNQQQLNAYPSGPAGVAGAQYLN----NPNLG-- DEHAN1_4_PE349 DEHAN1_4_PE349 NQEVNLGHVDRRMSAVADGAYYSANSYNAYPPESS----DPEFQSQYMQ----NVPLYDQ EMENI_36_PE362 EMENI_36_PE362 ---------------SSPGKSGNTYAFPPAT----------------------------- KLLAC1_2_PE244 KLLAC1_2_PE244 --------------DPFLYEKQ--------P---FPN----------------------- LACTH_6_PE229 LACTH_6_PE229 --------------APDAY-MYGMQFVPQQG---YPG----------------------- NEFIS1_277_PE105 NEFIS1_277_PE105 ---------------TSPGKSQNSYAFPPGP----------------------------- NEUCR_187_PE19 NEUCR_187_PE19 ---------------GSQ--------FSPA------------------------------ PENCW_10_PE703 PENCW_10_PE703 ---------------TSPGKSQGSYGFPSAP----------------------------- PHATR_26_PE12 PHATR_26_PE12 ------------------------------------------------------------ PICPG_2_PE1224 PICPG_2_PE1224 LD------------LSPSFKRNDQWFDSPSR---RES----------------------- PISTI1_4_PE509 PISTI1_4_PE509 NQEVVLGA-DRRMSAAVDGTYYGYGSYNGTNGSNSNSNIIPNYQSQYLQ----KNPTMPG YALIP1_4_PE623 YALIP1_4_PE623 MSSSP---------VTPQSASYNPWASPHST---PAG----NYARSRVSPVRKGQP--SQ YEASTX_PE89 YEASTX_PE89 --------------NPFQYDSYPAYTSSNTS---LAGNSSGQYPSGYQQQQQQVYQQGAI ZYGRO_4_PE119 ZYGRO_4_PE119 --------------NPFEYDDRNAYAGVYDP---QRQN-----------QIR-NMLLAQQ MATCH CONSENSUS ????????????????????????????????????????????????????????????

ASFUM1_4_PE267 ASFUM1_4_PE267 -------------------NNSRRSPTRA--LNYSSPAQSFQSPPS------------VS ASHGO_3_PE455 ASHGO_3_PE455 --------------YG--SEFQRRQSVAV--AGTYHSP---------------GYFETGA ASPCL_57_PE106 ASPCL_57_PE106 -------------------NNSRRSPTRA--SNYTSPPQAYQSPPS------------AS ASPFC_10_PE100 ASPFC_10_PE100 -------------------NNSRRSPTRA--LNYSSPAQSFQSPPS------------VS ASPFL_5_PE357 ASPFL_5_PE357 -------------------NQTRRSPTRV--PNYSSPPQPFQSPPS------------GS ASPNC_10_PE105 ASPNC_10_PE105 -------------------NQPRRSPTRG--STYASPPQAFQSPPS------------AS ASPNG_1_PE630 ASPNG_1_PE630 -------------------NQPRRSPTRG--STYASPPQAFQSPPS------------AS ASPOR_10_PE292 ASPOR_10_PE292 -------------------NQTRRSPTRV--PNYSSPPQPFQSPPCKLTSSCGLMKLAGS ASPTE_20_PE313 ASPTE_20_PE313 -------------------NQSRRSPTRA--PNYASPPQQYQSPPA------------GS CANAW_2_PE426 CANAW_2_PE426 ----------------PSVNANRRSSVGV-LPNYYRQQQQQQQ----------------- CANDC_2_PE425 CANDC_2_PE425 ----------------PSINANRRSSVGV-LPNYYRQQQQQQQ----------------- DEHAN1_4_PE349 DEHAN1_4_PE349 ---------------GL----NRRSSV---ATGNYH------------------------ EMENI_36_PE362 EMENI_36_PE362 -------------------HPSRQSPTRT--PNYSSPPQPFQSPPS------------GS KLLAC1_2_PE244 KLLAC1_2_PE244 --------------Y---NDAQRRQSVAV--TGGSQLS---------------PQQV--- LACTH_6_PE229 LACTH_6_PE229 --------------NS--QELHRRQSVAV--APQHS-------------------F---- NEFIS1_277_PE105 NEFIS1_277_PE105 -------------------NNSRRSPTRA--LNYSSPAQPFQSPPS------------VS NEUCR_187_PE19 NEUCR_187_PE19 ---------------------QRQSPTRP--NEYAPPQSQQQQQPPQQQQQQSPYYTSRQ PENCW_10_PE703 PENCW_10_PE703 -------------------QGASRRSPAR--PEYASPPQGYQSPPS-------------T PHATR_26_PE12 PHATR_26_PE12 ------------------------------------------------------------ PICPG_2_PE1224 PICPG_2_PE1224 ------------------NIAQQNLSLLQ--NGSRPSFS-----------QQLPTT---- PISTI1_4_PE509 PISTI1_4_PE509 ---------------AMGMMNNRRSSVAGIGSGYKH------------------------ YALIP1_4_PE623 YALIP1_4_PE623 QPQ--------------QQQQQQHQQTPQ--QHYNPAMP-----------ATKPYYWTQQ YEASTX_PE89 YEASTX_PE89 HPSQFGSRFVPSLYDR--QDFQRRQSLAA--TNYSSNF---------------SS----- ZYGRO_4_PE119 ZYGRO_4_PE119 QQQLAGARFVPSSFYGAGGDLHRRQSVAA--VHYPPSG---------------PTNLASL MATCH CONSENSUS ??????????????????????R?????????????????????????????????????

ASFUM1_4_PE267 ASFUM1_4_PE267 RP---PRLPPLQPT-EM---S-SDQFYPPSA--GSQVNAHF---------G------QDG ASHGO_3_PE455 ASHGO_3_PE455 QQPSTS--PSLMVA-HAVP-YRKLSAYPPLA--GALVPAAS---------LNSTLRGSA- ASPCL_57_PE106 ASPCL_57_PE106 RA---PRLPPLQST-EM---N-ADQFYPPPA--GPQANLPY---------G------ADG ASPFC_10_PE100 ASPFC_10_PE100 RP---PRLPPLQPT-EM---S-SDQFYPPSA--GSQVNAHF---------G------QDG ASPFL_5_PE357 ASPFL_5_PE357 RA---PRLPPLQPT-DM---S-PEQFYPPSA--GSQLSAPF---------G------QDG ASPNC_10_PE105 ASPNC_10_PE105 RP---PRLPPLQPT-DM---S-PDQYYPPSA--GSQLNAAF---------A------QDG ASPNG_1_PE630 ASPNG_1_PE630 RP---PRLPPLQPT-DM---S-PDQYYPPSA--GSQLNAAF---------A------QDG ASPOR_10_PE292 ASPOR_10_PE292 RA---PRLPPLQPT-DM---S-PEQFYPPSA--GSQLSAPF---------G------QDG ASPTE_20_PE313 ASPTE_20_PE313 RA---PRLPPLQST-EL---G-PDRYYPPSA--GSQLNTPF---------A------SDA CANAW_2_PE426 CANAW_2_PE426 ------QVQD-QSTAAAAAAAAAAAYYLPPARLGRSASIV-----QYQQYQQYQQ----- CANDC_2_PE425 CANDC_2_PE425 ------QVQI-QDPS--AAATAAAAYYLPPARLGRSASIV-----QYQQ---YQQ----- DEHAN1_4_PE349 DEHAN1_4_PE349 ----------------QAPHNTHVNYHHQPAKVGRSASIV-----QYQQY---QQ----- EMENI_36_PE362 EMENI_36_PE362 RP---PRLPPLQPT-DM---S-PDQFFGPSS--GPQLSSPF---------A------QDG KLLAC1_2_PE244 KLLAC1_2_PE244 TKPSQLRKPGINTAGYMAG-SINSSVYPATA--GAYMSTRG---------GSSSLPSSR- LACTH_6_PE229 LACTH_6_PE229 AQPALPADMSMHAP-MSPF-HRKLSSYPATA--GSVLPPPV---------K--QMRRQD- NEFIS1_277_PE105 NEFIS1_277_PE105 RP---PRLPPLQPT-EM---G-SDQFYPPSA--GSQVNAHF---------G------QDG NEUCR_187_PE19 NEUCR_187_PE19 AS---QQLPPINPY-AP---AQHDHSYPNSA-ISSTMDGSY---------M------DPK PENCW_10_PE703 PENCW_10_PE703 RP---PRLPPLQSG-DL---S-PNQYYPPSA--SSHMSPGF---------G------PGS PHATR_26_PE12 PHATR_26_PE12 ------------------------------------------------------------ PICPG_2_PE1224 PICPG_2_PE1224 -----------YEHEGMGPPAEEVVLPPPRA--AAPGPMQSHLNMQEEQFKEYQRRQSVA PISTI1_4_PE509 PISTI1_4_PE509 ----------------PPGPERGASYYLPQARVGRSPSIV-----QYQQY---QQ----- YALIP1_4_PE623 YALIP1_4_PE623 AQQTPQTQPPPITAPQSAPQAVHVAPQPIHA--APPQPPIQ---------P--QPQP--- YEASTX_PE89 YEASTX_PE89 --LNSNTNQGTNSIPVMSP-YRRLSAYPPST--SPPLQPPF---------K--QLRRDE- ZYGRO_4_PE119 ZYGRO_4_PE119 GAP-TNFTPAAGAATNMTP-YRRLSCYPPST--SPTASLQP---------PYKQLRRDAG MATCH CONSENSUS ??????????????????????????????A?????????????????????????????

ASFUM1_4_PE267 ASFUM1_4_PE267 RSPRSGSI-SGASKQAGRGPVPKFQKIKSVQELQPRINAQPPYRRANPEGGFISPLQALT ASHGO_3_PE455 ASHGO_3_PE455 --------------GGVAAAVPQMRKVGARQELAPVLHAMPKFRRASLNSKTVSPLIALT ASPCL_57_PE106 ASPCL_57_PE106 RSLRSASL-SGASNKPGQGPVPKFHKIKSVQELHPRIHQQPPYRRANPEGGFISPLQALT ASPFC_10_PE100 ASPFC_10_PE100 RSPRSGSI-SGASKQAGRGPVPKFQKIKSVQELQPRINAQPPYRRANPEGGFISPLQALT ASPFL_5_PE357 ASPFL_5_PE357 RSPRSASI-SGGSQQPGRGPVPKFQKIKSVQELKPRVNAQPPFRRANPEGGFISPLQALT ASPNC_10_PE105 ASPNC_10_PE105 RSPRSASI-SGGSQQPGRGPVPKFQKIKSIQELQPRMNAQPPYRRANPDGGFISPLQALT ASPNG_1_PE630 ASPNG_1_PE630 RSPRSASI-SGGSQQPGRGPVPKFQKIKSIQELQPRMNAQPPYRRANPDGGFISPLQALT ASPOR_10_PE292 ASPOR_10_PE292 RSPRSASI-SGGSQQPGRGPVPKFQKIKSVQELKPRVNAQPPFRRANPEGGFISPLQALT ASPTE_20_PE313 ASPTE_20_PE313 RSPPSAAV-SGGPPQPGRGPIPKFQKIKSVQDLHPRINMQPPYRRANPEGGFISPLQALT CANAW_2_PE426 CANAW_2_PE426 -------ALQNQRITKHKNPAPKARKIYNKLDLTPKFHQQPKYRRCSINSIHISPVNALS CANDC_2_PE425 CANDC_2_PE425 -------ALQNQRITKHKNPAPKARKIYNKLDLTPKFHQQPKYRRCSINSIHISPVNALS DEHAN1_4_PE349 DEHAN1_4_PE349 -------ALQNQSQTSKRNAAPKARKIYNKYDLHPKVHHQPKYRRCSVNSIHISPVNALS EMENI_36_PE362 EMENI_36_PE362 WSR---TG-SGAPQQPGRGPLPKFQKIKSIQDLKPRINAQPAYRRANPEGGFISPLQALT KLLAC1_2_PE244 KLLAC1_2_PE244 -------------PPSPIIIVPKFNKIFTRQDLNPVIHSTPKYRRASLSSKTVSPLMALT LACTH_6_PE229 LACTH_6_PE229 --------------EMIPVVLPQMHKVNARQDMRPTINATPKYRRASLDSRTVSPLVALT NEFIS1_277_PE105 NEFIS1_277_PE105 RSPRSGSM-SGASKQAGRGPVPKFQKIKSVQELQPRINAQPPYRRANPEGGFISPLQALT NEUCR_187_PE19 NEUCR_187_PE19 SPPRRMNSQSQQMPMPERTPVPEFRKIRGPQDLRPKINKQPAHRRANPEGGFISPLQALT PENCW_10_PE703 PENCW_10_PE703 RSPRSGSLPSQAPPVPGRGPVPKFQKIQSVQELKPRMNVQPAYRRANPEGGFISPLQSLT PHATR_26_PE12 PHATR_26_PE12 ------------------------------------------------------------ PICPG_2_PE1224 PICPG_2_PE1224 VSGSHYQTPPGAVTKTTKLPVPRMRRIRALSDFHPVRNAKPKYRRASSASQYISPLIALS PISTI1_4_PE509 PISTI1_4_PE509 -------SLPTQ--RLRRRPAPKAFKVYNKFDLNPKIHHQPKYRRCSVNSIHISPVNALS YALIP1_4_PE623 YALIP1_4_PE623 ------------QEPPASIPPPSFRPVERASDLNPQVNPRPQNRRAIPEGGYMSPLMCLT YEASTX_PE89 YEASTX_PE89 -------------VQGQKLSIPQMQLCNSKNDLQPVLNATPKFRRASLNSKTISPLVSVT ZYGRO_4_PE119 ZYGRO_4_PE119 AQGAMVG-----APSPQQVKIPQMQKCNSKSELKPTLNATPKYRRASLNSKTISPVIALT MATCH CONSENSUS ?????????????????????P???K??????L?P?????P??RR????????SP??AL?

ASFUM1_4_PE267 ASFUM1_4_PE267 SHLPATYRICNP-SFNYESSRNPRRVLTKPSKGVKNDGYDNEDSDYILYVNDILGSEEAG ASHGO_3_PE455 ASHGO_3_PE455 KSLIITYSLCSD-EFSYQTSKNPKRLLTKPSEGKLNNGHDNINSDYILYVNDVLGMEQ-- ASPCL_57_PE106 ASPCL_57_PE106 THLPATYRICNP-GFNYESSRNPRRVLTKPSKGVKNDGYDNEDSDYILYVNDILGSEEAG ASPFC_10_PE100 ASPFC_10_PE100 SHLPATYRICNP-SFNYESSRNPRRVLTKPSKGVKNDGYDNEDSDYILYVNDILGSEEAG ASPFL_5_PE357 ASPFL_5_PE357 THLPATYRICNP-GFNYESSRNPRRVLTKPSKGVKNDGYDNEDSDYILYVNDILGSEEAG ASPNC_10_PE105 ASPNC_10_PE105 THLPATYRICNP-GFNYESSRNPRRVLTKPSKGVKNDGYDNEDSDYILYVNDILGSEEAG ASPNG_1_PE630 ASPNG_1_PE630 THLPATYRICNP-GFNYESSRNPRRVLTKPSKGVKNDGYDNEDSDYILYVNDILGSEEAG ASPOR_10_PE292 ASPOR_10_PE292 THLPATYRICNP-GFNYESSRNPRRVLTKPSKGVKNDGYDNEDSDYILYVNDILGSEEAG ASPTE_20_PE313 ASPTE_20_PE313 THLPATYRICNP-GFNYESSRNPRRVLTKPSKGVKNDGFDNEESDYILYVNDILGSEEAG CANAW_2_PE426 CANAW_2_PE426 IYLTESYSLCQPRKFQYSKSTNPKRVLTKPSEPKYNNGYDNEDSDYILYVNDVLGSEE-- CANDC_2_PE425 CANDC_2_PE425 IYLTESYSLCQPRKFQYSKSTNPKRVLTKPSEPKYNNGYDNEDSDYILYVNDVLGSEE-- DEHAN1_4_PE349 DEHAN1_4_PE349 VYITESYRICQPKKFQYCKSTNPKRVLTKPSDAKYNNGFDNEDSDYILYVNDILGTDE-- EMENI_36_PE362 EMENI_36_PE362 NHLPATYRICNP-NFHYESSRNPRRVLTKPSKGVKNDGYDNEDSDYILYVNDILGSEEAG KLLAC1_2_PE244 KLLAC1_2_PE244 KSLTTTYSLCND-DFAYQTSKNPKRVLTKPNEGKYNNGHDNVNSDYILYVNDVLGVEH-- LACTH_6_PE229 LACTH_6_PE229 KSLTTTYTLCSP-EFSYQTSKNPKRVLTKPSEGKNNNGHDNINSDYILYVNDVLGTEQ-- NEFIS1_277_PE105 NEFIS1_277_PE105 SHLPATYRICNP-SFNYESSRNPRRVLTKPSKGVKNDGYDNEDSDYILYVNDILGSEEAG NEUCR_187_PE19 NEUCR_187_PE19 VHLPATYRICNP-GFKYESSRNPRRVLTKPSKGVKNDGYDNEDSDYILYVNDILGSEEAG PENCW_10_PE703 PENCW_10_PE703 THLPATYRICNP-GFNYESSRNPRRVLTKPSKGTKNDGYDNEDSDYILYVNDILGSEEAG PHATR_26_PE12 PHATR_26_PE12 --------------------------LTVPSEAVANDGVDNVEGNLIIFENDTISVPH-- PICPG_2_PE1224 PICPG_2_PE1224 ISLSSTYRICRP-EFSYNIAKNPRRVLTKPSEPKLNNGYDNIDSDYIQYVHDVLGIEE-- PISTI1_4_PE509 PISTI1_4_PE509 VYLTESYSICQPRKFQYSKSTNPKRVLTKPSDPKFNNGFDNEDSDYILYVNDILGTEE-- YALIP1_4_PE623 YALIP1_4_PE623 LQLSATYQICNS-GFNYESSKNPRRVLTKPSEPKLNNGHDNRDNDYILYVNDVLGTDE-- YEASTX_PE89 YEASTX_PE89 KSLITTYSLCSP-EFTYQTSKNPKRVLTKPSEGKCNNGFDNINSDYILYVNDVLGVEQ-- ZYGRO_4_PE119 ZYGRO_4_PE119 KGLITTYSLCSP-DFSYQTSKNPKRVLTKPNEGKYNGGYDNINSDYILYVNDVLGTEQ-- MATCH ** *.. *.* ** :.: * : :* :. . CONSENSUS ??L???Y??C?P??F?Y??S?NP?RVLTKPS????N?G?DN??SDYILYVND?LG?E???

ASFUM1_4_PE267 ASFUM1_4_PE267 HKNRYLILDVLGQGTFGQVVKCQNLKTQEVVAVKVIKNKTAYFNQSMMEVSVLDL----- ASHGO_3_PE455 ASHGO_3_PE455 -QRKYLILDILGQGTFGQVVKCQNMQTKEIVAVKVVKSKTEYLNQSIMEAKILEL----- ASPCL_57_PE106 ASPCL_57_PE106 HKNRYLILDVLGQGTFGQVVKCQNLKTQEVVAVKVIKNKTAYFNQSMMEVSVLDL----- ASPFC_10_PE100 ASPFC_10_PE100 HKNRYLILDVLGQGTFGQVVKCQNLKTQEVVAVKVIKNKTAYFNQSMMEVSVLDL----- ASPFL_5_PE357 ASPFL_5_PE357 HKNRYLILDVLGQGTFGQVVKCQNLKTQEVVAVKVIKNKTAYFNQSMMEVSVLDL----- ASPNC_10_PE105 ASPNC_10_PE105 HKNRYLILDVLGQGTFGQVVKCQNLKTGEVVAVKVIKNKTAYFNQSMMEVSVLDL----- ASPNG_1_PE630 ASPNG_1_PE630 HKNRYLILDVLGQGTFGQVVKCQNLKTGEVVAVKVIKNKTAYFNQSMMEVSVLDL----- ASPOR_10_PE292 ASPOR_10_PE292 HKNRYLILDVLGQGTFGQVVKCQNLKTQEVVAVKVIKNKTAYFNQSMMEVSVLDLVSCPL ASPTE_20_PE313 ASPTE_20_PE313 HKNRYLILDVLGQGTFGQVVKCQNLKTQEVVAVKVIKNKTAYFNQSMMEVSVLDL----- CANAW_2_PE426 CANAW_2_PE426 -GKKYMVLDLLGSGTFGQVVKCQNLNNQTVCAVKVIKSKPAYMNQSLTEVRLLEF----- CANDC_2_PE425 CANDC_2_PE425 -GKKYMVLDLLGSGTFGQVVKCQNLINQTVCAVKVIKSKPAYMNQSLTEVRLLEF----- DEHAN1_4_PE349 DEHAN1_4_PE349 -GRKYIVLDLLGSGTFGQVVKCQNLTNQSVCAIKVIKSKPAYMNQSLTEVKLLEY----- EMENI_36_PE362 EMENI_36_PE362 HKNRYLILDVLGQGTFGQVVKCQNLKTQEVVAVKVIKNKTAYFNQSMMEVSVLDL----- KLLAC1_2_PE244 KLLAC1_2_PE244 -NRKYLVLDLLGQGTFGQVVKCQNLITKEILAVKVVKSKSEYLNQSVTEAKVLEL----- LACTH_6_PE229 LACTH_6_PE229 -NRKYLVLDILGQGTFGQVVKCQNMLTKEILAVKVVKSKSEYLNQSITEAKILEL----- NEFIS1_277_PE105 NEFIS1_277_PE105 HKNRYLILDVLGQGTFGQVVKCQNLKTQEVVAVKVIKNKTAYFNQSMMEVSVLDL----- NEUCR_187_PE19 NEUCR_187_PE19 HKNRYLILDVLGQGTFGQVVKCQNLKTQEVVAVKVIKNRTAYFNQSMMEVSVLDL----- PENCW_10_PE703 PENCW_10_PE703 HKNRYLILDVLGQGTFGQVVKCQNLKTGEVVAVKVIKNKTAYFNQSMMEVSVLDL----- PHATR_26_PE12 PHATR_26_PE12 -QNIHVIQRLLGQGTFAQVFGCLHVQSGRSVAVKIVKNKPAYTRQATVEIDVFRA----- PICPG_2_PE1224 PICPG_2_PE1224 -NKKYMVLDILGQGTFGQVVKCQNLKTQEIVAVKVIKSKAAFLNQSMIEAEILDH----- PISTI1_4_PE509 PISTI1_4_PE509 -GRKYMVLDLLGSGTFGQVVKCQNLANQSVCAVKVIKSKPAYMNQSLTEVRLLEY----- YALIP1_4_PE623 YALIP1_4_PE623 -NKRYLVLDILGQGTFGQVVKCQNMKTKDIVAVKVIKNNPAFLNQSMMEVSILEY----- YEASTX_PE89 YEASTX_PE89 -NRKYLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILEL----- ZYGRO_4_PE119 ZYGRO_4_PE119 -NRKYLVLDILGQGTFGQVVKCQNILTKKIVAVKVVKSREEHLTQSITEARILDL----- MATCH . ::: :**.***.**. * :: . *:*::*.. . *: * :: CONSENSUS ????Y??LD?LGQGTFGQVVKCQN???????AVKV?K?K??Y?NQS??E???L???????

ASFUM1_4_PE267 ASFUM1_4_PE267 ------------LNSK---YDKNDDHHLLRLKDTFIHRQHLCLVFELLSVNLYELIKQNQ ASHGO_3_PE455 ASHGO_3_PE455 ------------LNKR---IDPLNQHHFLRLHDSFVHKNHLCLVFELLSNNLYELLKQNK ASPCL_57_PE106 ASPCL_57_PE106 ------------LNSK---YDKNDDHHLLRLKDTFIHRQHLCLVFELLSVNLYELIKQNQ ASPFC_10_PE100 ASPFC_10_PE100 ------------LNSK---YDKNDDHHLLRLKDTFIHRQHLCLVFELLSVNLYELIKQNQ ASPFL_5_PE357 ASPFL_5_PE357 ------------LNSR---YDKNDDHHLLRLKDTFIHRQHLCLVFEILSVNLYELIKQNQ ASPNC_10_PE105 ASPNC_10_PE105 ------------LNSR---YDKNDDHHLLRLKDTFIHRQHLCLVFELLSVNLYELIKQNQ ASPNG_1_PE630 ASPNG_1_PE630 ------------LNSR---YDKNDDHHLLRLKDTFIHRQHLCLVFELLSVNLYELIKQNQ ASPOR_10_PE292 ASPOR_10_PE292 LSTRVTCLLLSQLNSR---YDKNDDHHLLRLKDTFIHRQHLCLVFEILSVNLYELIKQNQ ASPTE_20_PE313 ASPTE_20_PE313 ------------LNSR---YDKNDDHHLLRLKDTFIHRQHLCLVFELLSVNLYELIKQNQ CANAW_2_PE426 CANAW_2_PE426 ------------LNAN------SDGKNFIRLLDTFMHKEHLCLVFEILASNLYELIKQNQ CANDC_2_PE425 CANDC_2_PE425 ------------LNTN------SDGKNFIRLLDTFMHKEHLCLVFEILASNLYELIKQNQ DEHAN1_4_PE349 DEHAN1_4_PE349 ------------LNSN------SNSKRFIRLLDTFMHKEHLCLVFELLASNLYELIKQNQ EMENI_36_PE362 EMENI_36_PE362 ------------LNSR---YDKNDDHHLLRLKDTFIHRQHLCLVFELLSVNLYELIKQNQ KLLAC1_2_PE244 KLLAC1_2_PE244 ------------LNRQ---IDPNNEHHFLRLHDTFVHKHHLCLVFELLSNNLYELLKLNE LACTH_6_PE229 LACTH_6_PE229 ------------LNSK---IDPLGEHHFLRMHETFVHRNHLCLVFELLSSNLYELLKQNQ NEFIS1_277_PE105 NEFIS1_277_PE105 ------------LNSK---YDKNDDHHLLRLKDTFIHRQHLCLVFELLSVNLYELIKQNQ NEUCR_187_PE19 NEUCR_187_PE19 ------------LNTK---LDKNDDHHLLRLKDTFIHRQHLCLVFELLSVNLYELIKQNQ PENCW_10_PE703 PENCW_10_PE703 ------------LNSK---YDKNDDHHLLRLKDTFIHRQHLCLAFELLSVNLYELIKQNQ PHATR_26_PE12 PHATR_26_PE12 ------------LQEDMTTEGAQGSEYILRLLCFFMYRSHLCLVFEMLGLNLYEVLKRRQ PICPG_2_PE1224 PICPG_2_PE1224 ------------LNKN---IDPQDVHHFLRLKDKFIHRNHLCLVFELLSSNLYELIKQNK PISTI1_4_PE509 PISTI1_4_PE509 ------------LNAN------SDGKNFIRLLDTFMHKEHLCLVFELLASNLYELIKQNQ YALIP1_4_PE623 YALIP1_4_PE623 ------------LNNS---VDNKDEHHILRLKDKFLHKQHYCLVFELLSSNLYELLKQNQ YEASTX_PE89 YEASTX_PE89 ------------LNQK---IDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNK ZYGRO_4_PE119 ZYGRO_4_PE119 ------------LNTK---VDPMNKHHILQMYDTFVHKNHLCLVFELLSNNLYELLKQNQ MATCH *: . . :::: *::: * **.**:*. ****::* .: CONSENSUS ????????????LN??????????????LRL?D?F?H??HLCLVFE?L??NLYEL?KQNQ

ASFUM1_4_PE267 ASFUM1_4_PE267 FRGLSTTLVRVFAQQLLNALSLLNKAHLIHCDLKPENILLKNLES-PIIKVIDFGSACDE ASHGO_3_PE455 ASHGO_3_PE455 FHGLSMNLIKNFCKQLLDSLCVLKESKLIHCDLKPENVLLVSPDR-PELKVIDFGSACEE ASPCL_57_PE106 ASPCL_57_PE106 FRGLSTTLVRVFAQQLLNALSLLNKAHLIHCDLKPENILLKNLES-PIIKVIDFGSACDE ASPFC_10_PE100 ASPFC_10_PE100 FRGLSTTLVRVFAQQLLNALSLLNKAHLIHCDLKPENILLKNLES-PIIKVIDFGSACDE ASPFL_5_PE357 ASPFL_5_PE357 FRGLSTTLVRVFAQQLLNALSLLNKAHLIHCDLKPENILLKNLES-PIIKVIDFGSACDE ASPNC_10_PE105 ASPNC_10_PE105 FRGLSTTLVRVFAQQLLNALSLLNKAHLIHCDLKPENILLKNLES-PIIKVIDFGSACDE ASPNG_1_PE630 ASPNG_1_PE630 FRGLSTTLVRVFAQQLLNALSLLNKAHLIHCDLKPENILLKNLES-PIIKVIDFGSACDE ASPOR_10_PE292 ASPOR_10_PE292 FRGLSTTLVRVFAQQLLNALSLLNKAHLIHCDLKPENILLKNLES-PIIKVIDFGSACDE ASPTE_20_PE313 ASPTE_20_PE313 FRGLSTTLVRVFAQQLLNALSLLNKAHLIHCDLKPENILLKNLES-PIIKVIDFGSACDE CANAW_2_PE426 CANAW_2_PE426 FQGLNMKLVKLLTKQLLDSMAQLKNFQMIHCDLKPENILLCQPDK-PNIKVIDFGSACFT CANDC_2_PE425 CANDC_2_PE425 FQGLNMKLVKLLTKQLLDSMAQLKNFQMIHCDLKPENILLCQPDK-PNIKVIDFGSACFT DEHAN1_4_PE349 DEHAN1_4_PE349 FQGLNMKLVKLLTRQLLEAMAELKGFQMIHCDLKPENILLFQPDK-PDIKVIDFGSACFT EMENI_36_PE362 EMENI_36_PE362 FRGLSTTLVRVFAQQLLNALSLLNKAHLIHCDLKPENILLKNLES-PIIKVIDFGSACDE KLLAC1_2_PE244 KLLAC1_2_PE244 FHGLSMTLIKTFSKQLLDSLCVLKDSKLIHCDLKPENILLVSNDR-PDLKVIDFGSACEE LACTH_6_PE229 LACTH_6_PE229 FHGLSISLIRSFARQLLDSLSVLKDNKLIHCDLKPENILLVSLDR-PELKVIDFGSACEE NEFIS1_277_PE105 NEFIS1_277_PE105 FRGLSTTLVRVFAQQLLNALSLLNKAHLIHCDLKPENILLKNLES-PIIKVIDFGSACDE NEUCR_187_PE19 NEUCR_187_PE19 FRGLSTTLVRVFAQQLLNGLSLLNKARLIHCDLKPENILLKNLES-PIIKIIDFGSACDE PENCW_10_PE703 PENCW_10_PE703 FRGLSTTLVRVFAQQLLNALSLLNKAHLIHCDLKPENILLKNLES-PIIKVIDFGSACDE PHATR_26_PE12 PHATR_26_PE12 FRGLPLSLVHQIVKQSVEGIKEFSRKNIVHCDLKPENVLLISNEVVESIKLIDFGSACFE PICPG_2_PE1224 PICPG_2_PE1224 FQGLSIKLVRKFAIQLLDSLCVLKNAKLVHCDLKPENILLVYPDK-PQLKIIDFGTACYE PISTI1_4_PE509 PISTI1_4_PE509 FQGLNMKLVKLLTRQLLEAMAQLRGFQMIHCDLKPENILLCQPDK-PDIKVIDFGSACFA YALIP1_4_PE623 YALIP1_4_PE623 FRGLSINLVRVFSRQLLDSLTVLKNAKLIHCDLKPENILLKNLDS-PIIKVIDFGSACHE YEASTX_PE89 YEASTX_PE89 FHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDK-PELKIIDFGSSCEE ZYGRO_4_PE119 ZYGRO_4_PE119 FHGLSMRLIRTFTAQLLDALCVLKDSKLVHCDLKPENVLLCSPDR-PDLKVIDFGSSCEE MATCH *:** *:: : * ::.: : .::********:** : :*:****::* CONSENSUS F?GL???L??????QLL?????L?????IHCDLKPENILL??????P??KVIDFGSAC?E

ASFUM1_4_PE267 ASFUM1_4_PE267 RQTVYTYIQSRFYRSPEVLLGLPY------------------SSAIDMWSLGCIVVELFL ASHGO_3_PE455 ASHGO_3_PE455 ARTVYTYIQSRFYRAPEVLMGIPY------------------STSIDMWSFGCIVAELFL ASPCL_57_PE106 ASPCL_57_PE106 RQTVYTYIQSRFYRSPEVLLGLPY------------------SSAIDMWSLGCIVVELFL ASPFC_10_PE100 ASPFC_10_PE100 RQTVYTYIQSRFYRSPEVLLGLPY------------------SSAIDMWSLGCIVVELFL ASPFL_5_PE357 ASPFL_5_PE357 RQTVYTYIQSRFYRSPEVLLGLPY------------------SSAIDMWSLGCIVVELFL ASPNC_10_PE105 ASPNC_10_PE105 RQTVYTYIQSRFYRSPEVLLGLPY------------------SSAIDMWSLGCIVVELFL ASPNG_1_PE630 ASPNG_1_PE630 RQTVYTYIQSRFYRSPEVLLGLPY------------------SSAIDMWSLGCIVVELFL ASPOR_10_PE292 ASPOR_10_PE292 RQTVYTYIQSRFYRSPEVLLGLPYVDIQCSLPPHDVHLRLTYSSAIDMWSLGCIVVELFL ASPTE_20_PE313 ASPTE_20_PE313 RQTVYTYIQSRFYRSPEVLLGLPY------------------SSAIDMWSLGCIVVELFL CANAW_2_PE426 CANAW_2_PE426 RNTIYTYIQSRFYRSPEVILGLPY------------------TESIDMWSLGCIVGELFL CANDC_2_PE425 CANDC_2_PE425 RNTIYTYIQSRFYRSPEVILGLPY------------------TESIDMWSLGCIVGELFL DEHAN1_4_PE349 DEHAN1_4_PE349 RQTVYSYIQSRFYRSPEVILGLPY------------------TESIDMWSLGCIVGELFL EMENI_36_PE362 EMENI_36_PE362 RQTVYTYIQSRFYRSPEVLLGLPY------------------SSAIDMWSLGCIVVELFL KLLAC1_2_PE244 KLLAC1_2_PE244 TRTIYTYIQSRFYRAPEVLLGIPY------------------STGIDMWSFGCIVAELFL LACTH_6_PE229 LACTH_6_PE229 TRTLYTYIQSRFYRAPEVILGIPY------------------STGIDMWSLGCIIAELFL NEFIS1_277_PE105 NEFIS1_277_PE105 RQTVYTYIQSRFYRSPEVLLGLPY------------------SSAIDMWSLGCIVVELFL NEUCR_187_PE19 NEUCR_187_PE19 RQTVYTYIQSRFYRSPEVLLGLPY------------------SSAIDMWSLGCIVVELFL PENCW_10_PE703 PENCW_10_PE703 RQTVYTYIQSRFYRSPEVLLGLPY------------------SSAIDMWSLGCIVVELFL PHATR_26_PE12 PHATR_26_PE12 GYPSHTYIQSRFYRSPEVLVGLPY------------------DSAIDMWSLGCVAAELFL PICPG_2_PE1224 PICPG_2_PE1224 GQPVYTYIQSRFYRSPEVVLGLSY------------------STSIDMWSFGCIVAELFL PISTI1_4_PE509 PISTI1_4_PE509 RQTIYTYIQSRFYRSPEVILGLPY------------------TESIDMWSLGCIVGELFL YALIP1_4_PE623 YALIP1_4_PE623 RKTVYTYIQSRFYRSPEVLLGIPY------------------TTSIDMWSMGCIIAELFL YEASTX_PE89 YEASTX_PE89 ARTVYTYIQSRFYRAPEIILGIPY------------------STSIDMWSLGCIVAELFL ZYGRO_4_PE119 ZYGRO_4_PE119 RRTIYTYIQSRFYRAPEVLFGIPY------------------STSIDMWSLGCIVAELFL MATCH . ::********:**::.*:.* .*****:**: **** CONSENSUS ??T?YTYIQSRFYR?PEV?LG?PY?????????????????????IDMWSLGCIV?ELFL

ASFUM1_4_PE267 ASFUM1_4_PE267 GLPLFPGSSEYNQVCRIVEMLGLPPTWMLEMGKQSGEFFEKTQD---------------- ASHGO_3_PE455 ASHGO_3_PE455 GIPVFPGASEFNQMTRIVEMLGVPPPWMCEMGKNTYNFFRKLH----------------- ASPCL_57_PE106 ASPCL_57_PE106 GLPLFPGSSEYNQVCRIVEMLGLPPTWMLEMGKQSGEFFEKTQD---------------- ASPFC_10_PE100 ASPFC_10_PE100 GLPLFPGSSEYNQVCRIVEMLGLPPTWMLEMGKQSGEFFEKTQD---------------- ASPFL_5_PE357 ASPFL_5_PE357 GLPLFPGSSEYNQVCRIVEMLGLPPTWMLEMGKQSGEFFEKTQD---------------- ASPNC_10_PE105 ASPNC_10_PE105 GLPLFPGSSEYNQVCRIVEMLGLPPTWMLEMGKQSGEFFEKTQD---------------- ASPNG_1_PE630 ASPNG_1_PE630 GLPLFPGSSEYNQVCRIVEMLGLPPTWMLEMGKQSGEFFEKTQD---------------- ASPOR_10_PE292 ASPOR_10_PE292 GLPLFPGSSEYNQVCRIVEMLGLPPTWMLEMGKQSGEFFEKTQD---------------- ASPTE_20_PE313 ASPTE_20_PE313 GLPLFPGSSEYNQVCRIVEMLGLPPTWMLEMGKQSGEFFEKTQD---------------- CANAW_2_PE426 CANAW_2_PE426 GLPMFPGTSEYNQIFKIVDMLGPPPRHMIEVGKNSFNFFKKKVNTTTTINNNNNNNNNNT CANDC_2_PE425 CANDC_2_PE425 GLPMFPGTSEYNQIYKIVDMLGLPPRHMIEVGKNSLNFFKKKIITTTTN--------TTN DEHAN1_4_PE349 DEHAN1_4_PE349 GLPMFPGTSEFNQIWKIVDMLGYPPRHMIEVGRNSLNFFNKFPP--------------SI EMENI_36_PE362 EMENI_36_PE362 GLPLFPGSSEYNQVCRIVEMLGLPPTWMLEMGKQSGEFFEKTQD---------------- KLLAC1_2_PE244 KLLAC1_2_PE244 GIPIFPGNSEFDQVTRIVESLGMPPAWMCDMGKNSKKYFHKMNT---------------- LACTH_6_PE229 LACTH_6_PE229 GIPIFPGSSEFNQITRVVDTLGLPPAWMLDMGRNTSNFMIKDE----------------- NEFIS1_277_PE105 NEFIS1_277_PE105 GLPLFPGSSEYNQVCRIVEMLGLPPTWMLEMGKQSGEFFEKTQD---------------- NEUCR_187_PE19 NEUCR_187_PE19 GLPLFPGSSEYNQVSRIVEMLGNPPNWMIEMGKQAGEFFEKRQD---------------- PENCW_10_PE703 PENCW_10_PE703 GLPLFPGSSEYNQICRIVEMLGIPPTWMLEMGKQSGEFFEKTQD---------------- PHATR_26_PE12 PHATR_26_PE12 GLPILPGVHEHDQLGRIEEMISRVPAWMLEQGAKTSKFFIKSPAS--------------- PICPG_2_PE1224 PICPG_2_PE1224 GLPLFPGTSEYNLLARVIDMLGMPPHFMIEMGKNSPNYFTRINS---------------- PISTI1_4_PE509 PISTI1_4_PE509 GLPMFPGTSEYNQIWKIVDMLGIPPRHMLEVGRNSMNFFKKIPA--------------GP YALIP1_4_PE623 YALIP1_4_PE623 GLPIFPGASEYNQLSRIVASLGDPPNWMVEMGKNSGKFMEKIVD---------------- YEASTX_PE89 YEASTX_PE89 GIPIFPGASEYNQLTRIIDTLGYPPSWMIDMGKNSGKFMKKLAPEES------------- ZYGRO_4_PE119 ZYGRO_4_PE119 GIPILPGVSEFNQVSRIVECLGYPPVWMMDMGKNTSRFMKKDDTLEEGLSFADG-DDGRL MATCH *:*::** *.: : :: :. * * : * :: .:: : CONSENSUS G?P?FPG?SE?NQ??RIV??LG?PP??M?E?GK????FF?K???????????????????

ASFUM1_4_PE267 ASFUM1_4_PE267 EFGRKTYRLKSLEQYSRE----------------------------HN---TKEQPSKKY ASHGO_3_PE455 ASHGO_3_PE455 -PQEKAWALKTVDEYNVE----------------------------FN---ASEEVGKQY ASPCL_57_PE106 ASPCL_57_PE106 EFGRKTYRLKSLEQYSRE----------------------------HN---TKEQPSKKY ASPFC_10_PE100 ASPFC_10_PE100 EFGRKTYRLKSLEQYSRE----------------------------HN---TKEQPSKKY ASPFL_5_PE357 ASPFL_5_PE357 EFGRKTYRLKGLEQYSRE----------------------------HG---TKEQPSKKY ASPNC_10_PE105 ASPNC_10_PE105 EFGRKTYRLKSLEQYSRE----------------------------HN---TKEQPSKKY ASPNG_1_PE630 ASPNG_1_PE630 EFGRKTYRLKSLEQYSRE----------------------------HN---TKEQPSKKY ASPOR_10_PE292 ASPOR_10_PE292 EFGRKTYRLKGLEQYSRE----------------------------HG---TKEQPSKKY ASPTE_20_PE313 ASPTE_20_PE313 EFGRKTYRLKSLEQYSRE----------------------------HN---TKEQPSKKY CANAW_2_PE426 CANAW_2_PE426 SETKPIYELKSFDEYCQFLEYKRQKQEGATSTTNNNTNSSSSSSNHHHNNYKKEQPNKNY CANDC_2_PE425 CANDC_2_PE425 PDTKPIYELKSFDEYCQFLEYKRQKQEGNTTTNT--TTTTNGSSQHHNHNYKKEQPNKNY DEHAN1_4_PE349 DEHAN1_4_PE349 PDGKPVFKVKTLEEYIQFLATTKGK----------------------EDQVKKEQPNKNY EMENI_36_PE362 EMENI_36_PE362 EFGRKSYRLKSLEQYSRE----------------------------HN---TKEQPSKKY KLLAC1_2_PE244 KLLAC1_2_PE244 -TVEKKFRMKTIDEFNLE----------------------------FA---ANEESVKRY LACTH_6_PE229 LACTH_6_PE229 -AGGKTWKVKSVEEYNMD----------------------------FG---SDEQPGKQY NEFIS1_277_PE105 NEFIS1_277_PE105 EFGRKTYRLKSLEQYSRE----------------------------HN---TKEQPSKKY NEUCR_187_PE19 NEUCR_187_PE19 EFGRKTYHLKSMEQYSRE----------------------------HG---TKEQPSKKY PENCW_10_PE703 PENCW_10_PE703 EFGRKTYRLKSLEQYSRE----------------------------HN---TKEQPSKKY PHATR_26_PE12 PHATR_26_PE12 GFSSLHFKRNYIASLSRDDIQK-----------------------QGGIEKLEKKPGNKY PICPG_2_PE1224 PICPG_2_PE1224 ----TQYKFKNVEQFSQD----------------------------PD-VWKRERESKSY PISTI1_4_PE509 PISTI1_4_PE509 GETRSTYSVKTYDEYLHFLETSKSK----------------------EDHPKKEQPNKNY YALIP1_4_PE623 YALIP1_4_PE623 DQGRKRYRLKSRERYSRE----------------------------FN---VDEKESKQY YEASTX_PE89 YEASTX_PE89 SSSTQKHRMKTIEEFCRE----------------------------YN---IVEKPSKQY ZYGRO_4_PE119 ZYGRO_4_PE119 GSPTMKYRLKTVDEYNQE----------------------------YS---SNEQPSKQY MATCH : :. : * CONSENSUS ?????????K????Y??????????????????????????????????????E?P?K?Y

ASFUM1_4_PE267 ASFUM1_4_PE267 FQASTLEEIIRSYPMPRKNMK-QAEIERELNNRVAFIDFVRGLLSINPLERWSPQQAKLH ASHGO_3_PE455 ASHGO_3_PE455 FKWTKLDDVIRNYRISKKIGASSQLLEREMQDRQCLTHFLFGVLNLNPLERWTPQQALLH ASPCL_57_PE106 ASPCL_57_PE106 FQASTLEEIIRSYPMPRKNMK-QAEIERELNNRVAFIDFVRGLLSINPLERWSPQQAKLH ASPFC_10_PE100 ASPFC_10_PE100 FQASTLEEIIRSYPMPRKNMK-QAEIERELNNRVAFIDFVRGLLSINPLERWSPQQAKLH ASPFL_5_PE357 ASPFL_5_PE357 FQASTLEEIIRSYPMPRKNMK-QAEIERELNNRVAFIDFVRGLLSINPLERWSPQQAKLH ASPNC_10_PE105 ASPNC_10_PE105 FQASTLEEIIRSYPMPRKNMK-QAEIERELNNRVAFIDFVRGLLAINPLERWSPQQAKLH ASPNG_1_PE630 ASPNG_1_PE630 FQASTLEEIIRSYPMPRKNMK-QAEIERELNNRVAFIDFVRGLLAINPLERWSPQQAKLH ASPOR_10_PE292 ASPOR_10_PE292 FQASTLEEIIRSYPMPRKNMK-QAEIERELNNRVAFIDFVRGLLSINPLERWSPQQAKLH ASPTE_20_PE313 ASPTE_20_PE313 FQQNTLEEIIRNYPMPRKHMK-PAEMERELNNRVAFIDFVRGLLTINPLERWSPQQAKLH CANAW_2_PE426 CANAW_2_PE426 FKHKLLKDIIINYKLPSKKMT-NSMIEKEYHDRLLLIDFLTKVLNLNPLERLTPQEALKH CANDC_2_PE425 CANDC_2_PE425 FKHKLLKDIIINYKLPSKKMT-NSMIEKEYHDRLLLIDFLTKVLNLNPLERLTPQEALKH DEHAN1_4_PE349 DEHAN1_4_PE349 FKHRLLKDIIMNYKLPSKKMT-NSMIEKECQERLLLIDFLSKVLNLNPLERLTPQEALKH EMENI_36_PE362 EMENI_36_PE362 FQASTLEEIIRSYPMPRKNMK-QAEIEREVNNRVAFIDFVRGLLSINPLERWSPQQAKLH KLLAC1_2_PE244 KLLAC1_2_PE244 VKHILFDDIIRNARISKRISGNPALVEREIKNRDCLLHFLRGVLNLNPLERWTPQQAILH LACTH_6_PE229 LACTH_6_PE229 FKWRKLDDIIQNYRISKKIAGAPALVEKERQERVCLTHFLHGLLNINPLERWTPTQAAMH NEFIS1_277_PE105 NEFIS1_277_PE105 FQASTLEEIIRSYPMPRKNMK-QAEIERELNNRVAFIDFVRGLLSINPLERWSPQQAKLH NEUCR_187_PE19 NEUCR_187_PE19 FQANTLPEIIKTYPMPRKNMK-QSEIDREMNNRIAFIDFVRGLLTINPLERWSPQQAKLH PENCW_10_PE703 PENCW_10_PE703 FSASTLEEIIRSYPMPRKNMK-QAEIDRELNNRVAFIDFVRGLLSINPLERWSPQQAKLH PHATR_26_PE12 PHATR_26_PE12 FKRKRLSDILTLHGQ--------NTQKEDQDLLPAFVHFLYGLLDPDPWKRTTAFQALHH PICPG_2_PE1224 PICPG_2_PE1224 FTHRYLNEIILNYELPKKNMT-YSMIDKEMRQRECLVHFLMGVLNLNPLKRWSPQQASAH PISTI1_4_PE509 PISTI1_4_PE509 FKHRILKDIILNYKLPSKKMT-NSMIEKECSERLLLIDFLSKVLNLNPLERLTPQEALKH YALIP1_4_PE623 YALIP1_4_PE623 FTSANLKTIIMEYPLHKKDMK-RADIDKEMLNREALYDFLMGLLNYNPFERWTPQQAASH YEASTX_PE89 YEASTX_PE89 FKWRKLPDIIRNYRYPKSIQNSQELIDQEMQNRECLIHFLGGVLNLNPLERWTPQQAMLH ZYGRO_4_PE119 ZYGRO_4_PE119 FKWTKMPDIIKNYRYSKKIKGNPELIEQEQRDRDCLIHFLRGVLNINPLERWTPQLASMH MATCH . : :: ..: : .*: :* :* :* :. * * CONSENSUS F????L??II??Y????K??????????E???R?????F??G?L??NPLER??PQ?A??H

ASFUM1_4_PE267 ASFUM1_4_PE267 PFITQQKFTGPFVPPMNLKYSSLNKTIP--PGIQQQQQAEAASKQRAAQAAHAQSA---A ASHGO_3_PE455 ASHGO_3_PE455 PFITGQPFDKEWYPPGTLPKKVNKL-----PSLQDG----A-T----------------- ASPCL_57_PE106 ASPCL_57_PE106 PFITQQKFTGPFVPPMNLKYSSLNKTIA--PGIQQQQQAEAASKQRAAQAAHAQSA---A ASPFC_10_PE100 ASPFC_10_PE100 PFITQQKFTGPFVPPMNLKYSSLNKTIP--PGIQQQQQAEAASKQRAAQAAHAQSA---A ASPFL_5_PE357 ASPFL_5_PE357 PFITQQKFTGPFVPPMNLKYSSLNKTVA--PGIQQQQQAEAASKQRAAQAAHAQSA---A ASPNC_10_PE105 ASPNC_10_PE105 PFITQQKFTGPFMPPMNLKYSSLNKTVP--PGIQQQQQAEAASKQRAAQAAHAQSA---A ASPNG_1_PE630 ASPNG_1_PE630 PFITQQKFTGPFMPPMNLKYSSLNKTVP--PGIQQQQQAEAASKQRAAQAAHAQSA---A ASPOR_10_PE292 ASPOR_10_PE292 PFITQQKFTGPFVPPMNLKYSSLNKTVA--PGIQQQQQAEAASKQRAAQAAHAQSA---A ASPTE_20_PE313 ASPTE_20_PE313 PFITQQKFTGPFVPPMNLKYSSLNKTIA--PGIQQQQQAEAASKQRAAHVAHAQSAA--A CANAW_2_PE426 CANAW_2_PE426 PFIIDVNTTDL------------------------------------------------- CANDC_2_PE425 CANDC_2_PE425 PFIIDVNTNDL------------------------------------------------- DEHAN1_4_PE349 DEHAN1_4_PE349 PFVSDVSLHHPSTSSTASSGDRSSN----HSDLSDN-LKDAG------------------ EMENI_36_PE362 EMENI_36_PE362 PFITQQKFTGPFVPPMNLKYSSLNKTLP--PGIQQQQQAEAASKQRAAHAQS----A--A KLLAC1_2_PE244 KLLAC1_2_PE244 PFITEEPFTGEWYPPGTIPKKSQTA-----RNPSLQ----FDS----------------- LACTH_6_PE229 LACTH_6_PE229 PFITQQPFSGEWFPPGSTPRRTAKT-----PVLQER----STT----------------- NEFIS1_277_PE105 NEFIS1_277_PE105 PFITQQKFTGPFVPPMNLKYSSLNKTIP--PGIQQQQQAEAASKQRAAQAAHAQSA---A NEUCR_187_PE19 NEUCR_187_PE19 PFITQSKFTGPFVPPMNLKSSSLNRSPA--PGTQQQIQAEAFSKQKAQQAQANAIAANQA PENCW_10_PE703 PENCW_10_PE703 PFITQQKFTGPFMPPMNLKYSTANKP-A--PGVQQQQQAEAASKQRAAQAAH-------A PHATR_26_PE12 PHATR_26_PE12 PFLT-------------------------------------------------------- PICPG_2_PE1224 PICPG_2_PE1224 PFITGQPFNSNWTPPGFSVHNSGGSETELHSSEKTQETQ-PEP--------STYSNT-PV PISTI1_4_PE509 PISTI1_4_PE509 PFVVDVRTVDSTSSSTSSGSSDR------------------------------------- YALIP1_4_PE623 YALIP1_4_PE623 PFITESKFTGPFVPHPKEEKDVFHPTPTAQPISQSQPLHAQGQ--------NANAMV-PP YEASTX_PE89 YEASTX_PE89 PFITKQEFTGEWFPPGSSLPGPSEK-----HDDAKGQQSEYGS--------ANDSSN-NA ZYGRO_4_PE119 ZYGRO_4_PE119 PFVTQQPFTGEWYPPGTLQSTATSN-----STN--------------------DSTI-PP MATCH **: CONSENSUS PFIT????????????????????????????????????????????????????????

ASFUM1_4_PE267 ASFUM1_4_PE267 QNAYSMQMNQFHTPSHGQP--PPMYN--GMFAG----HQQGAPPPYPAQ-PPGYGHQM-- ASHGO_3_PE455 ASHGO_3_PE455 ------------------------------------------------------------ ASPCL_57_PE106 ASPCL_57_PE106 QNAYSMQLNQFHTPSHAQP--PPMYN--GMFTG----HQQGAPPPYPTQ-PPGYGHQM-- ASPFC_10_PE100 ASPFC_10_PE100 QNAYSMQMNQFHTPSHGQP--PPMYN--GMFAG----HQQGAPPPYPAQ-PPGYGHQM-- ASPFL_5_PE357 ASPFL_5_PE357 QTAYSMQLNQFHTPTHAQP-PPPMYN--GVFTG----HQQGAPPPYPTQQPPGYGHQM-- ASPNC_10_PE105 ASPNC_10_PE105 QNAYAMQLNQFHTPTHAQP--PPMYN--GIFTG----HQQGAPPPYPTQ-PPAYGHQM-- ASPNG_1_PE630 ASPNG_1_PE630 QNAYAMQLNQFHTPTHAQP--PPMYN--GIFTG----HQQGAPPPYPTQ-PPAYGHQM-- ASPOR_10_PE292 ASPOR_10_PE292 QTAYSMQLNQFHTPTHAQP-PPPMYN--GVFTG----HQQGAPPPYPTQQPPGYGHQM-- ASPTE_20_PE313 ASPTE_20_PE313 QQAYSLQMNQFHNPNHAAQ-PPPMYN--GMYTG----HQQGAPPPYPTQ-PPTYGHQM-- CANAW_2_PE426 CANAW_2_PE426 ------------------------------------------------------------ CANDC_2_PE425 CANDC_2_PE425 ------------------------------------------------------------ DEHAN1_4_PE349 DEHAN1_4_PE349 -----------------------------KAPTGGISDSSRAPIPS-------------- EMENI_36_PE362 EMENI_36_PE362 QSAYTMQMNQYHPSAHAQP-PPPMYT--GMYGG----HQQP-PPPYPTQ-PPAYGHQM-- KLLAC1_2_PE244 KLLAC1_2_PE244 ------------------------------------------------------------ LACTH_6_PE229 LACTH_6_PE229 ------------------------------------------------------------ NEFIS1_277_PE105 NEFIS1_277_PE105 QNAYSMQMNQFHTPSHGQP--PPMYN--GMFTG----HQQGAPPPYPAQ-PPGYGHQM-- NEUCR_187_PE19 NEUCR_187_PE19 QNPYGSMATGQQYPQQTHTQPQPLYSNNNIYAPGGSSSHASAPPPYGSQQGAYPQQGMPQ PENCW_10_PE703 PENCW_10_PE703 QNAYAVQMNQFHTPPQPQPQAPPMYN--GMYQQ------GAPPPPYPTQQPPGYGHQM-- PHATR_26_PE12 PHATR_26_PE12 ------------------------------------------------------------ PICPG_2_PE1224 PICPG_2_PE1224 SQAYRSSFTKQERPPQQ--------------------------------HQYSYGYASSQ PISTI1_4_PE509 PISTI1_4_PE509 ------------------------------------------------------------ YALIP1_4_PE623 YALIP1_4_PE623 GPAAGSSAA--QTSAEA--------------------------------AQYA--HMQPP YEASTX_PE89 YEASTX_PE89 GHN----YV--YNP-------------------------------------------S-- ZYGRO_4_PE119 ZYGRO_4_PE119 GMNKNIGNI--KHP-------------------------------------------SLQ MATCH CONSENSUS ????????????????????????????????????????????????????????????

ASFUM1_4_PE267 ASFUM1_4_PE267 ----NLMPGQMPQSQYAP--SQSLYAQA---TTRAGRQRASTMDHQGGGIPPTIQRVASH ASHGO_3_PE455 ASHGO_3_PE455 --------KELN-------------KLH---LGE-------------------------- ASPCL_57_PE106 ASPCL_57_PE106 ----NIIPGQMPQSQYAP--SQSLYAQA---TTRAGRQRASTMDHQGAGIPPTIQRVASH ASPFC_10_PE100 ASPFC_10_PE100 ----NLMPGQMPQSQYAP--SQSLYAQA---TTRAGRQRASTMDHQGGGIPPTIQRVASH ASPFL_5_PE357 ASPFL_5_PE357 ----NLIPGQMPQSQYAP--SQSLYAQA---TTRAGRQRASTMDPQGGGIPPTIQRVASH ASPNC_10_PE105 ASPNC_10_PE105 ----NLIPGQVPQAQYAP--SQSLYAQA---TTRAGRQRASTMDPQGGGIPPTIQRVASH ASPNG_1_PE630 ASPNG_1_PE630 ----NLIPGQVPQAQYAP--SQSLYAQA---TTRAGRQRASTMDPQGGGIPPTIQRVASH ASPOR_10_PE292 ASPOR_10_PE292 ----NLMPGQMPQSQYAP--SQSLYAQA---TTRAGRQRASTMDPQGGGIPPTIQRVASH ASPTE_20_PE313 ASPTE_20_PE313 ----NLMPGQMPQTQYAP--SQSLYAQA---TTRAGRQRASTMDPQGGGIPPTIQRVASH CANAW_2_PE426 CANAW_2_PE426 ------------------------------------------------------------ CANDC_2_PE425 CANDC_2_PE425 ------------------------------------------------------------ DEHAN1_4_PE349 DEHAN1_4_PE349 ------------------------------------------------------------ EMENI_36_PE362 EMENI_36_PE362 ----NLMPGQMPQTQYGA--SQSLYAQA---TTRAGRQRASTMDPQ--GVPPTIQRVASH KLLAC1_2_PE244 KLLAC1_2_PE244 --------VALD-------------KLQ---LGD-------------------------- LACTH_6_PE229 LACTH_6_PE229 --------SEID-------------KLH---IAD-------------------------- NEFIS1_277_PE105 NEFIS1_277_PE105 ----NLMPGQMPQSQYAP--SQSLYAQA---TTRAGRQRASTMDHQGGGIPPTIQRVASH NEUCR_187_PE19 NEUCR_187_PE19 QQQPQVPQVQMPPANYAGVSQSNLYAQQQAAAAARQRQRSSTMEQQQSGIPVSIQRVASH PENCW_10_PE703 PENCW_10_PE703 ----GMMPGNQ-----VP--AQSLYAQA---TTRAGRQRASTMDPNG-GIPTTIQRVASH PHATR_26_PE12 PHATR_26_PE12 ------------------------------------------------------------ PICPG_2_PE1224 PICPG_2_PE1224 AI----PPKEVPKSKLQQ--YTSNYSVS---SGSSSSKSSS-MAGSITGEDIETDTGQTM PISTI1_4_PE509 PISTI1_4_PE509 ------------------------------------------------------------ YALIP1_4_PE623 YALIP1_4_PE623 AN----WSTGLK-------------QQN---SGSGSRRPRALTYGSMDPIPPPIQRATAM YEASTX_PE89 YEASTX_PE89 -S----ATGGAD-------------SVD---IGAISKRKEN-TSGDIS-------NNFA- ZYGRO_4_PE119 ZYGRO_4_PE119 EG----TAKEFD-------------RLR---IGED------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

ASFUM1_4_PE267 ASFUM1_4_PE267 LDPNAPIRLQPSPAYYPPPPDGYVDNNAQRR---RGSRAG-----A-GQRNRDFIRTLED ASHGO_3_PE455 ASHGO_3_PE455 ------------------------------------------------------------ ASPCL_57_PE106 ASPCL_57_PE106 LDPNAPIRLQPSPAYYPPPPDGYVDSNAQRR---RGSRTG-----ATGQRNRDFVRTLED ASPFC_10_PE100 ASPFC_10_PE100 LDPNAPIRLQPSPAYYPPPPDGYVDNNAQRR---RGSRAG-----A-GQRNRDFIRTLED ASPFL_5_PE357 ASPFL_5_PE357 LDPNAPIRLQPSPAYYPPPPDGYVDAGAANQ---RRRGSR-----AGGTRNRDFIRTLED ASPNC_10_PE105 ASPNC_10_PE105 LDPNAPIRLQPSPAYYPPPPDGYVDPNSAGQ---RRRGSR-----TGGTRNRDFIRTLED ASPNG_1_PE630 ASPNG_1_PE630 LDPNAPIRLQPSPAYYPPPPDGYVDPNSAGQ---RRRGSR-----TGGTRNRDFIRTLED ASPOR_10_PE292 ASPOR_10_PE292 LDPNAPIRLQPSPAYYPPPPDGYVDAGAANQ---RRRGSR-----AGGTRNRDFIRTLED ASPTE_20_PE313 ASPTE_20_PE313 LDPNAPIRLQPSPAYYPPPADGYVDNAG-NQ---RRRGSR-----AGATRNRDFIRTLED CANAW_2_PE426 CANAW_2_PE426 ------------------------------------------------------------ CANDC_2_PE425 CANDC_2_PE425 ------------------------------------------------------------ DEHAN1_4_PE349 DEHAN1_4_PE349 ------------------------------------------------------------ EMENI_36_PE362 EMENI_36_PE362 LDPNAPIRLQPSPAYYPPPADGYADPNSANQ---RRRGSR-----VGGTRNRDFIRTLED KLLAC1_2_PE244 KLLAC1_2_PE244 ------------------------------------------------------------ LACTH_6_PE229 LACTH_6_PE229 ------------------------------------------------------------ NEFIS1_277_PE105 NEFIS1_277_PE105 LDPNAPIRLQPSPAYYPPPPDGYVDNNAQRR---RGSRAG-----A-GQRNRDFIRTLED NEUCR_187_PE19 NEUCR_187_PE19 LDPTQPIRLQPSPAYYPPPPDGLMGMDSQPSQRMPRRGSRAQASGRGQGNNRDFIRNLEE PENCW_10_PE703 PENCW_10_PE703 LDPNAPIRLQPSPAYYPPPPDGYVDANSS-Q---RRRGSRA-GNGNGNQRNRDFIRTLED PHATR_26_PE12 PHATR_26_PE12 ------------------------------------------------------------ PICPG_2_PE1224 PICPG_2_PE1224 FKQGYSIQKASDKK---------------------------------------------- PISTI1_4_PE509 PISTI1_4_PE509 ------------------------------------------------------------ YALIP1_4_PE623 YALIP1_4_PE623 VNPADHIQAQPSPAYIPPSELTRNHQG-------------------QGNEYGEVVRKLEN YEASTX_PE89 YEASTX_PE89 --VTHSVQEGPTSAFNKLHIVEE------------------------------------- ZYGRO_4_PE119 ZYGRO_4_PE119 ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

ASFUM1_4_PE267 ASFUM1_4_PE267 G-----VLGGD-GYMNQSQWH ASHGO_3_PE455 ASHGO_3_PE455 --------------------- ASPCL_57_PE106 ASPCL_57_PE106 G-----VLGGD-NYMSQGQWH ASPFC_10_PE100 ASPFC_10_PE100 G-----VLGGD-GYMNQSQWH ASPFL_5_PE357 ASPFL_5_PE357 G-----VLGGD-GFMGQNQWH ASPNC_10_PE105 ASPNC_10_PE105 G-----VLGGE-GFMGQNQWH ASPNG_1_PE630 ASPNG_1_PE630 G-----VLGGE-GFMGQNQWH ASPOR_10_PE292 ASPOR_10_PE292 G-----VLGGD-GFMGQNQWH ASPTE_20_PE313 ASPTE_20_PE313 G-----VLGGD-GFMAQNQWH CANAW_2_PE426 CANAW_2_PE426 --------------------- CANDC_2_PE425 CANDC_2_PE425 --------------------- DEHAN1_4_PE349 DEHAN1_4_PE349 --------------------- EMENI_36_PE362 EMENI_36_PE362 G-----VLG-D-GYMGQNQWH KLLAC1_2_PE244 KLLAC1_2_PE244 --------------------- LACTH_6_PE229 LACTH_6_PE229 --------------------- NEFIS1_277_PE105 NEFIS1_277_PE105 G-----VLGGD-SYMNQSQWH NEUCR_187_PE19 NEUCR_187_PE19 RTLEEGFMGGNGGGQGQSQWH PENCW_10_PE703 PENCW_10_PE703 G-----VLS-E-GYMGQNQWH PHATR_26_PE12 PHATR_26_PE12 --------------------- PICPG_2_PE1224 PICPG_2_PE1224 --------------------- PISTI1_4_PE509 PISTI1_4_PE509 --------------------- YALIP1_4_PE623 YALIP1_4_PE623 GLMS--------------RW- YEASTX_PE89 YEASTX_PE89 --------------------- ZYGRO_4_PE119 ZYGRO_4_PE119 --------------------- MATCH CONSENSUS ?????????????????????


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