Alignment of the gene Family HOG000282644 of HOGENOM
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Threshold:
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Normal
Isoforms are
ON
PLAKH_4_PE102
PLAKH_4_PE102
M
K
T
N
Y
S
N
V
R
V
S
F
V
Y
S
E
K
V
N
E
L
V
E
K
V
I
F
L
A
K
S
L
S
H
Y
R
K
K
Y
V
T
F
L
K
K
R
K
C
E
V
Q
G
K
S
G
S
Y
T
G
R
PLAVI_10_PE104
PLAVI_10_PE104
M
K
T
N
H
S
N
V
R
T
S
F
V
Y
S
K
K
V
N
E
L
T
E
K
V
I
F
L
A
K
S
L
S
H
Y
R
K
K
Y
V
T
F
L
K
G
R
K
C
E
V
G
G
E
S
G
S
Y
T
G
R
MATCH
****:****.*****:*****.********************** ***** *:*******
CONSENSUS
MKTN?SNVR?SFVYS?KVNEL?EKVIFLAKSLSHYRKKYVTFLK?RKCEV?G?SGSYTGR
PLAKH_4_PE102
PLAKH_4_PE102
G
Y
I
R
K
S
S
L
S
R
S
G
H
S
E
T
D
G
DV
K
G
R
RG
K
K
NYT
V
W
R
M
K
Y
N
E
Q
S
Q
A
G
C
S
F
F
H
V
F
T
N
Y
E
E
L
V
H
E
L
PLAVI_10_PE104
PLAVI_10_PE104
G
D
I
R
K
S
S
I
S
R
S
G
N
S
E
T
G
G
GG
K
G
R
QE
K
K
HHA
V
K
R
A
K
W
N
E
E
S
R
A
G
C
S
F
F
H
V
F
T
S
Y
E
E
F
V
H
D
L
MATCH
* *****:****:***.*. ***: **:::* * *:**:*:**********.***:**:*
CONSENSUS
G?IRKSS?SRSG?SET?G??KGR??KK???V?R?K?NE?S?AGCSFFHVFT?YEE?VH?L
PLAKH_4_PE102
PLAKH_4_PE102
L
Y
L
C
S
H
E
T
D
I
Y
I
E
F
L
Y
T
L
I
I
N
S
D
L
F
N
H
F
L
Y
I
C
T
F
T
S
G
D
K
D
D
P
F
L
L
L
I
Y
K
H
F
L
T
L
V
E
Y
Y
F
Y
PLAVI_10_PE104
PLAVI_10_PE104
L
H
L
C
S
H
E
T
D
I
Y
I
E
F
L
Y
T
L
I
I
N
S
E
L
F
N
H
F
L
Y
I
C
T
F
T
S
G
D
K
D
D
R
F
L
L
L
I
Y
K
H
F
L
I
L
V
E
Y
Y
F
Y
MATCH
*:********************:****************** ********** *******
CONSENSUS
L?LCSHETDIYIEFLYTLIINS?LFNHFLYICTFTSGDKDD?FLLLIYKHFL?LVEYYFY
PLAKH_4_PE102
PLAKH_4_PE102
F
N
N
C
H
Y
F
N
D
L
Y
C
S
L
K
E
I
Y
D
N
K
D
V
C
E
A
G
L
R
A
P
P
WG
C
T
F
L
R
K
N
D
K
N
Y
L
NS
Q
A
K
Y
E
Q
HDS
T
TW
PLAVI_10_PE104
PLAVI_10_PE104
F
N
N
C
H
Y
F
N
E
L
Y
R
S
L
K
G
I
Y
D
N
K
D
V
C
E
A
G
L
R
A
P
P
RR
C
A
F
L
R
E
N
D
K
N
C
L
TG
Q
A
K
Y
E
Q
NGP
T
SR
MATCH
********:** *** **************** *:***:**** *..******:..*:
CONSENSUS
FNNCHYFN?LY?SLK?IYDNKDVCEAGLRAPP??C?FLR?NDKN?L??QAKYEQ???T??
PLAKH_4_PE102
PLAKH_4_PE102
M
E
E
E
N
K
F
L
F
T
Y
P
N
E
N
S
D
F
A
N
Y
E
RN
G
G
R
K
K
EC
E
M
K
KR
S
R
K
T
N
R
C
R
F
D
V
R
E
S
G
N
T
F
K
D
T
EEK
PLAVI_10_PE104
PLAVI_10_PE104
T
E
G
E
N
N
F
L
F
T
Y
P
S
E
S
S
D
F
V
N
Y
E
HS
G
G
R
K
K
KG
E
V
K
NG
S
R
K
T
N
R
C
S
F
E
V
N
E
S
G
N
T
F
K
E
T
DKH
MATCH
* **:******.*.***.***:.*****: *:*: ******* *:*.*******:*:::
CONSENSUS
?E?EN?FLFTYP?E?SDF?NYE??GGRKK??E?K??SRKTNRC?F?V?ESGNTFK?T???
PLAKH_4_PE102
PLAKH_4_PE102
L
I
S
ER
N
V
S
T
F
T
K
V
V
K
E
R
G
A
N
D
TH
G
GGE
C
D
G
N
T
I
K
A
E
KI
T
P
S
SE
I
L
S
K
F
R
S
S
A
S
GDMEE
D
N
PLAVI_10_PE104
PLAVI_10_PE104
L
L
S
QL
N
V
S
S
F
T
K
G
V
E
E
R
A
A
N
D
AR
G
EAK
C
H
G
N
T
V
K
A
E
ES
T
H
S
RA
I
L
S
N
F
L
S
H
A
S
SGADG
D
I
MATCH
*:*: ***:*** *:**.***::* .:*.***:***: * * ***:* * **.. : *
CONSENSUS
L?S??NVS?FTK?V?ER?AND??G???C?GNT?KAE??T?S??ILS?F?S?AS?????D?
PLAKH_4_PE102
PLAKH_4_PE102
QV
D
F
H
C
K
Y
NC
N
F
D
H
G
E
K
K
K
K
H
S
C
H
P
E
M
A
H
S
S
N
A
N
F
N
I
N
N
F
Y
K
L
K
N
M
F
S
M
F
N
K
L
N
Y
E
H
L
Y
I
PLAVI_10_PE104
PLAVI_10_PE104
PG
D
F
H
C
N
Y
HY
N
C
D
D
G
E
K
K
K
K
H
V
C
H
R
E
L
A
H
P
S
N
A
N
F
N
V
N
D
F
Y
K
L
K
N
M
F
L
M
F
N
K
L
N
Y
E
H
L
Y
I
MATCH
****:*: * *.******* ** *:**.******:*:******** ************
CONSENSUS
??DFHC?Y??N?D?GEKKKKH?CH?E?AH?SNANFN?N?FYKLKNMF?MFNKLNYEHLYI
PLAKH_4_PE102
PLAKH_4_PE102
L
L
Y
F
S
L
S
I
L
P
T
L
F
H
V
Y
L
T
R
V
L
T
T
R
R
D
E
S
C
I
S
P
Y
L
M
Y
I
A
K
K
I
K
E
R
S
IHS
F
K
FY
C
N
G
T
TR
E
S
PLAVI_10_PE104
PLAVI_10_PE104
L
L
Y
F
S
L
S
I
L
P
T
L
F
H
V
Y
L
T
R
V
L
T
T
R
R
E
E
S
R
I
S
P
Y
L
M
Y
V
A
K
R
I
K
E
R
S
TRF
F
K
ID
C
N
G
T
AG
E
R
MATCH
*************************:** *******:**:***** : **: ****: *
CONSENSUS
LLYFSLSILPTLFHVYLTRVLTTRR?ES?ISPYLMY?AK?IKERS???FK??CNGT??E?
PLAKH_4_PE102
PLAKH_4_PE102
G
Y
SQ
V
S
FI
G
E
A
H
DR
V
Q
S
T
G
S
I
N
N
R
Y
L
P
K
G
D
V
Q
K
G
V
CAKGRRHESNDQSDGEWSD
Q
R
K
D
A
H
PLAVI_10_PE104
PLAVI_10_PE104
G
Y
CA
V
S
PR
G
E
A
H
KG
V
D
S
T
G
P
I
N
N
R
H
L
L
K
G
D
V
Q
R
G
V
RSDE-----------QRGE
Q
R
K
G
A
H
MATCH
**. ** ****. *:***.****:* *****:** :. : .:***.**
CONSENSUS
GY??VS??GEAH??V?STG?INNR?L?KGDVQ?GV???????????????????QRK?AH
PLAKH_4_PE102
PLAKH_4_PE102
F
V
W
D
E
P
N
D
K
L
W
E
H
I
N
R
L
D
IHE
K
L
D
T
L
K
S
G
G
D
T
S
R
N
Y
S
DV
F
R
R
N
I
S
L
L
H
A
F
E
I
RS
D
F
E
N
L
N
PLAVI_10_PE104
PLAVI_10_PE104
T
V
W
D
E
P
N
D
K
L
W
E
H
I
D
R
L
D
VQA
K
L
D
A
L
R
S
G
G
D
A
S
R
D
Y
S
AE
F
R
R
N
I
N
L
L
H
A
F
E
I
KG
D
F
E
S
L
N
MATCH
*************:***:: ***:*:****:**:** *****.*******:.***.**
CONSENSUS
?VWDEPNDKLWEHI?RLD???KLD?L?SGGD?SR?YS??FRRNI?LLHAFEI??DFE?LN
PLAKH_4_PE102
PLAKH_4_PE102
Y
E
I
V
D
E
HERSSN---------G
K
KRN
S
E
N
K
S
D
G
ST
H
R
H
EQM
R
V
N
QWNHT
N
Q
Q
N
RAFGEII
PLAVI_10_PE104
PLAVI_10_PE104
Y
E
V
V
E
E
QKEGGVKDKKRSGNDK
K
RSG
S
E
N
K
P
D
G
NP
H
R
H
ARR
R
A
N
EASPA
N
Q
Q
N
GI-----
MATCH
**:*:*::... *: .****.**..*** : *.*: . :****
CONSENSUS
YE?V?E????????????????K???SENK?DG??HRH???R?N?????NQQN???????
PLAKH_4_PE102
PLAKH_4_PE102
TK
G
RS
K
E
G
R
EK
T
KYS
G
P
SH
Q
AGH
V
D
E
IV
S
I
Q
S
V
P
VM
S
R
E
H
T
P
M
Y
D
PEK
E
L
Q
D
V
L
K
R
N
L
QF
PLAVI_10_PE104
PLAVI_10_PE104
-S
G
GA
K
G
G
R
DG
T
THA
G
P
PN
Q
TDE
V
D
E
TA
S
I
Q
S
V
P
LK
S
K
E
R
T
P
V
Y
D
AGR
E
L
Q
E
V
L
K
R
N
L
RW
MATCH
.* :* **: *.::**.:*:..*** .******: *:*:**:**. :***:******::
CONSENSUS
??G??K?GR??T???GP??Q???VDE??SIQSVP??S?E?TP?YD???ELQ?VLKRNL??
PLAKH_4_PE102
PLAKH_4_PE102
N
R
I
H
L
F
Y
RN
E
L
K
T
DDS
L
Q
N
A
R
G
L
R
D
F
I
K
S
I
S
I
I
C
S
E
Q
F
F
S
F
Y
M
N
R
I
D
M
K
K
S
T
Q
G
D
Y
H
L
L
Q
PLAVI_10_PE104
PLAVI_10_PE104
N
R
I
H
S
F
Y
LS
E
V
K
T
PRG
L
Q
N
A
R
G
L
Q
D
F
I
K
S
I
S
I
I
C
S
E
Q
F
F
S
F
Y
M
N
R
I
D
M
K
K
S
T
E
G
D
Y
H
L
L
H
MATCH
**** ** .*:** .*******:****************************:******:
CONSENSUS
NRIH?FY??E?KT???LQNARGL?DFIKSISIICSEQFFSFYMNRIDMKKST?GDYHLL?
PLAKH_4_PE102
PLAKH_4_PE102
VD
K
C
S
S
A
S
M
K
HRR
E
D
E
A
H
W
G
E
Q
Q
MNN
P
G
K
H
L
H
M
Q
S
L
H
K
D
T
T
L
I
H
N
D
Y
I
K
K
K
I
K
R
N
R
L
Y
T
Y
PLAVI_10_PE104
PLAVI_10_PE104
AH
K
C
S
S
A
S
M
K
QKT
E
E
E
A
H
W
G
E
R
Q
TTH
P
G
N
H
L
H
M
P
S
L
H
K
D
T
T
L
I
H
N
E
Y
I
K
K
K
I
K
R
N
R
L
Y
T
Y
MATCH
..********:: *:******:* .:**:**** ***********:**************
CONSENSUS
??KCSSASMK???E?EAHWGE?Q???PG?HLHM?SLHKDTTLIHN?YIKKKIKRNRLYTY
PLAKH_4_PE102
PLAKH_4_PE102
K
I
F
N
N
Q
I
E
T
L
L
N
S
K
E
L
A
E
Y
I
K
K
Q
K
E
N
K
K
K
K
K
K
Y
Q
E
E
K
K
K
E
N
F
I
Y
M
Q
S
Q
G
G
C
P
L
L
N
K
K
N
KR
PLAVI_10_PE104
PLAVI_10_PE104
K
I
F
N
N
Q
I
E
T
L
L
N
S
K
E
L
A
E
C
I
K
K
Q
K
E
N
K
K
K
K
K
K
S
Q
E
E
K
K
K
E
N
F
I
Y
M
Q
S
Q
S
G
C
P
L
L
N
K
K
N
RK
MATCH
****************** ************* ***************.*********::
CONSENSUS
KIFNNQIETLLNSKELAE?IKKQKENKKKKKK?QEEKKKENFIYMQSQ?GCPLLNKKN??
PLAKH_4_PE102
PLAKH_4_PE102
K
VSNI
P
F
T
F
A
Q
N
K
N
E
N
F
I
E
S
D
C
N
S
Y
E
N
S
D
S
S
D
N
L
S
M
Y
N
Y
S
K
E
F
Y
L
D
NG
F
N
I
N
EFI
F
F
V
L
N
PLAVI_10_PE104
PLAVI_10_PE104
K
IWDV
P
F
T
F
S
Q
N
K
N
E
N
V
I
E
S
D
C
N
T
Y
E
D
S
D
S
S
D
N
L
S
M
Y
N
Y
T
K
E
F
Y
A
D
SR
F
N
I
N
DLV
F
F
L
L
N
MATCH
*: ::****:******.******:**:************:**** *. ****:::**:**
CONSENSUS
K????PFTF?QNKNEN?IESDCN?YE?SDSSDNLSMYNY?KEFY?D??FNIN???FF?LN
PLAKH_4_PE102
PLAKH_4_PE102
T
F
Y
L
F
M
H
I
H
N
V
Y
F
S
C
T
Y
L
N
V
L
L
S
Y
S
I
K
L
V
F
K
Y
S
D
R
C
V
G
S
R
L
T
R
L
L
R
G
H
LS
G
E
YNK
H
Q
E
RD
PLAVI_10_PE104
PLAVI_10_PE104
S
F
Y
L
F
M
H
I
H
N
I
Y
F
S
C
T
Y
L
N
V
L
L
S
Y
S
I
K
L
V
F
K
Y
S
D
R
C
V
G
S
R
L
A
R
L
L
R
G
H
SP
G
E
KSS
H
G
E
NS
MATCH
:*********:******************************:****** .** ..* *..
CONSENSUS
?FYLFMHIHN?YFSCTYLNVLLSYSIKLVFKYSDRCVGSRL?RLLRGH??GE???H?E??
PLAKH_4_PE102
PLAKH_4_PE102
F-----------------------------------------------------------
PLAVI_10_PE104
PLAVI_10_PE104
GHGESGKGVASPSVLPLCVHLHMSIPLFVTLNHPLSDVPANPIDTTEDATPPFAAHNRVK
MATCH
CONSENSUS
????????????????????????????????????????????????????????????
PLAKH_4_PE102
PLAKH_4_PE102
-------------------RTTIK
N
TE
E
G
S
E
L
E
R
I
K
Q
L
S
E
M
I
L
R
K
K
K
F
F
N
K
K
K
K
K
E
K
N
L
H
PLAVI_10_PE104
PLAVI_10_PE104
ITRKGSIIRVMKSLREEGDIHKTV
N
PQ
E
G
S
E
L
E
R
I
K
E
L
S
E
M
I
I
R
K
K
K
F
F
N
K
K
K
K
K
E
K
N
L
N
MATCH
. *.:*********:*****:****************:
CONSENSUS
????????????????????????N??EGSELERIK?LSEMI?RKKKFFNKKKKKEKNL?
PLAKH_4_PE102
PLAKH_4_PE102
C
S
F
S
SACR
K
YG
N
K
T
T
L
L
M
N
T
F
D
I
I
L
N
S
F
L
D
L
C
I
S
L
C
S
V
N
F
N
F
VN
D
K
R
R
R
L
N
R
T
Y
F
C
DS
I
C
PLAVI_10_PE104
PLAVI_10_PE104
C
S
F
S
PSSS
K
CE
N
K
T
A
L
L
M
N
T
F
D
I
I
L
N
S
F
L
D
L
C
I
S
L
C
S
V
D
F
Q
F
LS
D
R
R
K
R
L
N
R
A
Y
F
C
KC
I
C
MATCH
****.:. * ***:***********************:*:*:.*:*:****:***..**
CONSENSUS
CSFS????K??NKT?LLMNTFDIILNSFLDLCISLCSV?F?F??D?R?RLNR?YFC??IC
PLAKH_4_PE102
PLAKH_4_PE102
R
Y
H
Y
M
L
N
R
Q
Y
N
E
S
AMHK
F
N
Q
A
N
Y
NN
S
V
E
A
Y
L
F
Y
F
D
E
L
K
KHE
L
F
S
KQIL
G
D
G
KTET
G
RGD
S
PLAVI_10_PE104
PLAVI_10_PE104
R
Y
H
H
M
L
N
R
Q
Y
E
E
S
SLRR
F
N
R
A
N
Y
DH
S
V
E
A
Y
L
F
Y
F
D
E
L
K
RTR
L
F
S
NRVA
G
G
G
GSRA
G
HPR
S
MATCH
***:******:**::::**:***::*************: .***::: *.* :.:*: *
CONSENSUS
RYH?MLNRQY?ES????FN?ANY??SVEAYLFYFDELK???LFS????G?G????G???S
PLAKH_4_PE102
PLAKH_4_PE102
R
SR
H
NQS
D
S---------------------IHV
S
NR
S
D
D
S
SY
S
L
Y
F
SKDKRKSTMIHLGV
PLAVI_10_PE104
PLAVI_10_PE104
R
--
H
LAA
D
RSNHSDGSDGSDGSDGSDGSDGSDG
S
DG
S
D
G
S
GH
S
M
Y
F
PRESA---------
MATCH
* * :* . *: **.*.:*:**.::.
CONSENSUS
R??H???D?????????????????????????S??SD?S??S?YF??????????????
PLAKH_4_PE102
PLAKH_4_PE102
NEKEMTRKE
K
E
H
K
KCV
L
VER
V
K
K
SATE
K
R
L
IK
K
R
M
D
D
S
I
F
S
Q
M
M
M
T
R
G
SV
N
AKSYA
S
S
WM
PLAVI_10_PE104
PLAVI_10_PE104
------PNG
K
E
H
K
NGG
L
AQQ
V
-
K
NDAG
K
R
L
PN
K
K
M
D
D
S
I
F
S
H
M
M
M
A
R
G
GG
N
TGGNT
S
S
SV
MATCH
: ****: *.::* *. : *** :*:*******:***:**. *: . :** :
CONSENSUS
?????????KEHK???L???V?K????KRL??K?MDDSIFS?MMM?RG??N?????SS??
PLAKH_4_PE102
PLAKH_4_PE102
N
E
T
GGKQK
G
D
D
V
P
I
D
SM
N
I
S
S
D
G
S
F
L
F
L
K
K
M
K
K
K
I
K
K
R
I
Y
L
D
E
N
N
I
I
K
M
L
T
C
V
G
C
I
F
M
N
N
PLAVI_10_PE104
PLAVI_10_PE104
N
L
T
EEDHH
G
E
D
V
P
I
D
PV
N
T
S
S
D
G
S
F
L
F
L
K
K
M
K
K
K
I
K
K
R
I
Y
L
D
E
N
N
I
I
K
M
L
T
S
V
G
C
I
F
M
N
N
MATCH
* * .::*:*****.:* ********************************.********
CONSENSUS
N?T?????G?DVPID??N?SSDGSFLFLKKMKKKIKKRIYLDENNIIKMLT?VGCIFMNN
PLAKH_4_PE102
PLAKH_4_PE102
I
K
Y
S
V
G
I
T
I
N
N
L
K
K
V
C
K
N
G
P
S
N
ENN
H
LF
N
QLN
G
I
F
Y
C
Q
K
K
NV
H
L
A
N
I
Y
N
Q
Y
F
V
S
F
L
F
F
F
K
PLAVI_10_PE104
PLAVI_10_PE104
I
K
Y
S
V
G
I
T
I
K
N
L
K
R
V
A
K
N
G
P
S
N
QRD
H
FL
N
HFS
G
M
F
Y
G
Q
K
K
GS
H
L
A
S
I
Y
N
Q
Y
F
V
S
F
L
F
F
F
K
MATCH
*********:***:*.******:.:*::*::.*:** ***. ***.**************
CONSENSUS
IKYSVGITI?NLK?V?KNGPSN???H??N???G?FY?QKK??HLA?IYNQYFVSFLFFFK
PLAKH_4_PE102
PLAKH_4_PE102
I
H
Y
L
F
F
L
I
K
Y
K
C
E
N
E
I
F
L
K
A
Y
W
F
L
Y
A
V
Y
SI
T
Q
G
PLAVI_10_PE104
PLAVI_10_PE104
M
H
Y
L
F
F
L
I
K
Y
K
C
E
N
E
I
F
L
K
A
Y
W
F
L
Y
A
V
Y
AV
T
Q
G
MATCH
:***************************::***
CONSENSUS
?HYLFFLIKYKCENEIFLKAYWFLYAVY??TQG
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