Alignment of the gene Family HOG000288759 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AERS4_4_PE638 AERS4_4_PE638 ----------------------------------------------ML--HH-----GKL COLP3_1_PE1177 COLP3_1_PE1177 --------------------------------------------------------MNKF FERBD_1_PE786 FERBD_1_PE786 ----------------------------------------------ML----------CQ FERBD_1_PE792 FERBD_1_PE792 ----------------------------------------------MQ----------KY SHEAM_1_PE1004 SHEAM_1_PE1004 ------------------------------------------------------------ SHEAM_1_PE926 SHEAM_1_PE926 -----------------------------------------------------------M SHEB2_1_PE3163 SHEB2_1_PE3163 -----------------------------------------------------------M SHEB5_5_PE1048 SHEB5_5_PE1048 -----------------------------------------------------------M SHEB8_2_PE1107 SHEB8_2_PE1107 -----------------------------------------------------------M SHEB9_1_PE1157 SHEB9_1_PE1157 -----------------------------------------------------------M SHEDO_1_PE2698 SHEDO_1_PE2698 -----------------------------------------------------------M SHEFN_1_PE2860 SHEFN_1_PE2860 -----------------------------------------------------------M SHEHH_1_PE1131 SHEHH_1_PE1131 ------------------------------------------------------------ SHELP_1_PE1104 SHELP_1_PE1104 ------------------------------------------------------------ SHELP_1_PE1176 SHELP_1_PE1176 -------------------------------MDILRAGQSALANIIMQR--------KGE SHEPA_1_PE1088 SHEPA_1_PE1088 -----------------------------------------------------------M SHEPC_1_PE1058 SHEPC_1_PE1058 ------------------------------------------------------------ SHEPW_1_PE3541 SHEPW_1_PE3541 -----------------------------------------------------------M SHESA_2_PE1077 SHESA_2_PE1077 ----------------MIPFLFKCQPHNRLVFSIARASSLISLNSRPQNVRHTLTSVISL SHESA_2_PE3108 SHESA_2_PE3108 -----------------------------------------------------------M SHESH_1_PE1199 SHESH_1_PE1199 -----------------------------------------------------------M SHESM_1_PE1085 SHESM_1_PE1085 ----------------MISCLFTYQFENRLVFSLARISSLISLNIRPQNVRHTLTSLFSL SHESM_1_PE2939 SHESM_1_PE2939 ------------------------------------------------------------ SHESR_2_PE1146 SHESR_2_PE1146 ----------------MISCLFTYQFENRLVFSLARISSLISLNIRPQNVRHTLTSLFSL SHESR_2_PE3010 SHESR_2_PE3010 -----------------------------------------------------------M SHESW_1_PE3061 SHESW_1_PE3061 ------------------------------------------------------------ SHEVD_1_PE1009 SHEVD_1_PE1009 -----------------------------------------------------------M SHEVD_1_PE1172 SHEVD_1_PE1172 FVLVDLLLPTFKKTTTMINFCFAFIVN-----AVKSQGQVLPLAKIISLKNHS----FGL SHEWM_1_PE1289 SHEWM_1_PE1289 -----------------------------------------------------------M SHEWM_1_PE1358 SHEWM_1_PE1358 ---MSIFAPELTAI----------------------CGQV---CSRLTAIGRSTFSYRRF SHONE1_1_PE3211 SHONE1_1_PE3211 -----------------------------------------------------------M MATCH CONSENSUS ????????????????????????????????????????????????????????????

AERS4_4_PE638 AERS4_4_PE638 WLM--ALCA--LSVPAVAGDAYSDDTELFIYDFSKAGDYRPKVLVIFDNSGSMAETMELE COLP3_1_PE1177 COLP3_1_PE1177 IAKG----ILALILATLSNVTLSEDIDLYISEAVRQANKKTKVLIIFDTSGSMKEISRFG FERBD_1_PE786 FERBD_1_PE786 GRAVVLAA----SLSAAMGMAIADDTELYVAGGLATGAGRPQVLIIFDNSGSMDTEEAVA FERBD_1_PE792 FERBD_1_PE792 RYRGVLAAAFSAIAVVVSNATMADDTELYVAGIQDEDASRPKVLIIFDNSGSMLELEWVE SHEAM_1_PE1004 SHEAM_1_PE1004 ------------MACLLWTPLYADDTSLYVYESSNRSDERPQVLVIFDNSGSMDTTVYGV SHEAM_1_PE926 SHEAM_1_PE926 KFNQ-ILFAGLVTASVLPAQSFADDTDLYLNP--AANNVRPQVLIIFDNSGSMDTIVDGV SHEB2_1_PE3163 SHEB2_1_PE3163 IIKK-LACSTLLVLTFVSAYSFGDDTELYVKESTTRTGARPKVLVIFDNSGSMSTEEITQ SHEB5_5_PE1048 SHEB5_5_PE1048 IIKK-LACSTLLVLTFVSAYSFGDDTELYVKESTTRTGARPKVLVIFDNSGSMSTEEITQ SHEB8_2_PE1107 SHEB8_2_PE1107 IIKR-LACSTLLVLTFVSAYSFGDDTELYVKESTTRTGARPKVLVIFDNSGSMSTEEITQ SHEB9_1_PE1157 SHEB9_1_PE1157 IIKE-LACSTLLVLTFVSAYSFGDDTELYVKESTTRTGARPKVLVIFDNSGSMSTEEITQ SHEDO_1_PE2698 SHEDO_1_PE2698 LTRI-CGFSVFFAVLMGAATSHADDTELYVFESSSRSGARPQVMIIFDNSGSMRTVEPDA SHEFN_1_PE2860 SHEFN_1_PE2860 FSKY-PIFIMLFSVLGFVANAVADDTELYVLESSVRSDDNPQVLIILDTSGSMGNTMSAS SHEHH_1_PE1131 SHEHH_1_PE1131 MIKN-LFCSAIAASIIVSACSFADDTELYLVDPNKATGKLPQVLFIFDNSGSMSTEDQNA SHELP_1_PE1104 SHELP_1_PE1104 MFKK-LLCSTVMALVVVSGMTIADDTELYLIDSNVRSGKRPQVLFVFDNSGSMSTEDQNA SHELP_1_PE1176 SHELP_1_PE1176 LVKS-FVALLTAIMSLLSASSWADDTELYVYEASARTGARPQILIIFDNSGSMSTKVYDV SHEPA_1_PE1088 SHEPA_1_PE1088 LGKR-ILTAVAFAVVVLSGASHSDDTELYVYESTARSGARPQVLIIFDNSGSMGNMVDDA SHEPC_1_PE1058 SHEPC_1_PE1058 MLNK-CLIGLLTALIIMLDAVYADDTELYLIDSTVRSGKRPQVLFIFDNSGSMSTIEENA SHEPW_1_PE3541 SHEPW_1_PE3541 KFGQ-FLIIVATVLIMISGASYSDDTELYVFESSARSGSRPQVLIIFDNSGSMRTQEYS- SHESA_2_PE1077 SHESA_2_PE1077 ILSS-VIVSA---ASLFMAPTHADDTELYVFEASARNGSRPQVLIIFDNSGSMSSLAYDV SHESA_2_PE3108 SHESA_2_PE3108 LIKP-LTFCTLFAFIAAPVSTFGDDTELYVKESTTRTGARPKVLVIFDNSGSMSTEEITQ SHESH_1_PE1199 SHESH_1_PE1199 FYKN-CLCGVFTVLVILSSGTFADDTELYLIDSSVNTGKRPQVLFVFDNSGSMSTEDQNA SHESM_1_PE1085 SHESM_1_PE1085 ILSS-VIVSA---ASLFMAPTHADDTELYVFEASARNGSRPQVLIIFDNSGSMSNLAYDV SHESM_1_PE2939 SHESM_1_PE2939 MFKK-ILCALSVTFVVIAGQIHADDTELYLVDSSVKTGKRPQILIIFDNSGSMSTEDTNV SHESR_2_PE1146 SHESR_2_PE1146 ILSS-VIVSA---ASLFMAPTHADDTELYVFEASARNGSRPQVLIIFDNSGSMSNLAYDV SHESR_2_PE3010 SHESR_2_PE3010 KFNQ-YLFAGFVVALAVPAHTLADDTDIYLNP--AQNNIRPQVLIIFDNSASMDTMVEGL SHESW_1_PE3061 SHESW_1_PE3061 MLNK-CLIGLLTALIIMLDAVYADDTELYLIDSTVRSGKRPQVLFIFDNSGSMSTIEENA SHEVD_1_PE1009 SHEVD_1_PE1009 WIKR-FLCAVLMGLGMISGVTHGDDTELYVFESSARSGARPQVLIIFDNSGSMGTMIEDA SHEVD_1_PE1172 SHEVD_1_PE1172 FFGI-VLAIS---A--APFFSFADDTQLYVFESTARTGARPQMLIIFDNSGSMGARVYDV SHEWM_1_PE1289 SHEWM_1_PE1289 IVKH-VACVALFVLVGISAGTFADDTDLYVVESSVRTGANPKVLIIFDNSGSMTTIEEDA SHEWM_1_PE1358 SHEWM_1_PE1358 RLSS-FLISSSAIYILFPHSILADDTELYVHEASARSGARPQMLIIFDNSGSMNTTVVGA SHONE1_1_PE3211 SHONE1_1_PE3211 LIKK-LTFCTLLALASTSISSFGDDTELYVKESSTRTGARPKVLVIFDNSGSMSTEEITQ MATCH .:* .::: .:::.::*.*.** CONSENSUS ???????????????????????DDTELY??????????RP?VL?IFDNSGSM???????

AERS4_4_PE638 AERS4_4_PE638 REKYNPATVYPS-------------LSRDPDTGNSRNYVYYSTD------GSV---PAIN COLP3_1_PE1177 COLP3_1_PE1177 E-PYINDPDNPY-------------IATDSAHAYDDNMLYFNRA-GADNTT--TIPNSPS FERBD_1_PE786 FERBD_1_PE786 AAPFDPTYDYTG---------------------DNGDRIYYIKG-SADP-DEYPDPLDSD FERBD_1_PE792 FERBD_1_PE792 AGPYDPNHDYTG---------------------EGGNRLYYVKG-AVST-DQYPDPQDSN SHEAM_1_PE1004 SHEAM_1_PE1004 NPSFSSADG--D-------------LS-------ESEQVYYSLD---AA-EAPPNPANPA SHEAM_1_PE926 SHEAM_1_PE926 AGGYDPNYTQEDGTLGYPA------VGSSN--SYQGRMIYFTVGTGMDE-SSLPVPDSPS SHEB2_1_PE3163 SHEB2_1_PE3163 VVDYDPNYDYPA-------------VSGSG--YSDT-LIYYTVG-G----GGLPTPDTSS SHEB5_5_PE1048 SHEB5_5_PE1048 VVDYDPNYNYPA-------------VSGSG--YSDT-LIYYAVG-G----GGLPTPDTSS SHEB8_2_PE1107 SHEB8_2_PE1107 VVDYDPNYDYPA-------------VSGSG--YSDT-LIYYAVG-G----GGLPTPDTSS SHEB9_1_PE1157 SHEB9_1_PE1157 VVDYDPNYDYPA-------------VSGSG--YSDT-LIYYAVG-G----GGLPTPDTSS SHEDO_1_PE2698 SHEDO_1_PE2698 TAFYDPNVIYPA-------------VGSGN--ALQERMVYFTKG-GIDN-TAMPVPDSPS SHEFN_1_PE2860 SHEFN_1_PE2860 PFLVQPNLT-------------------------SGTKLYYSTSS-----STV---PTAN SHEHH_1_PE1131 SHEHH_1_PE1131 VSKYCSAAGKAAGDCSYADGFEDYLAGYSG--YINGAGIYWNAG-GIDNTSSMPVPDVPK SHELP_1_PE1104 SHELP_1_PE1104 TSSYCSADDKANGICDYADGFGDYLAGYSG--YINEKGIYWNAG-GIDNTSNMPTPDEPK SHELP_1_PE1176 SHELP_1_PE1176 DKPYTPGAG--G-------------GSRYN--NGKKGMLYYVKG-DQGK-NKLPDPDDPN SHEPA_1_PE1088 SHEPA_1_PE1088 EAFYDPDVTYPA-------------VGSDN--SLQERMVYFTKG-GIDN-TAMPVPDSPS SHEPC_1_PE1058 SHEPC_1_PE1058 VTSYCSEAGKAAGTCSYPTGFDNFLSGYSG--YINNKGTYWNAG-GIDNTNNMPTPDKPN SHEPW_1_PE3541 SHEPW_1_PE3541 ENFYSRGET-----------------------VNDGTKLYYAKG-GGS------V-PEPT SHESA_2_PE1077 SHESA_2_PE1077 EAPYENK-------------------RAVN--YAQSGNLFYSRG-SSEN-AAAPNPNSRR SHESA_2_PE3108 SHESA_2_PE3108 VVDYDPSYDYPP-------------VSGSG--YSDS-RIYYTVG-G----GALPTPDTNS SHESH_1_PE1199 SHESH_1_PE1199 VSSYCSAADKASGGCNYAEGFGTYLEGYHG--YINDKGIYWNAG-GIDNTASMPVPEDPN SHESM_1_PE1085 SHESM_1_PE1085 EAPYENK-------------------RAVN--YAQSGNLFYSRG-SSEN-AAAPNPNSGR SHESM_1_PE2939 SHESM_1_PE2939 VSSYCSAADQAASNCTYPDGFATYLEGYSG--YISQKGIYWNAG-GIDNTSNAPTPDSPN SHESR_2_PE1146 SHESR_2_PE1146 EAPYENK-------------------RAVN--YAQSGNLFYSRG-SSEN-AAAPNPNSGR SHESR_2_PE3010 SHESR_2_PE3010 PGGYKPNVT-------YTP------LDSAN--SYQDDMIYFTVGTGLDE-SGLGIPDSPS SHESW_1_PE3061 SHESW_1_PE3061 VTSYCSEAGKAAGTCSYPTGFDNFLSGYSG--YINNKGTYWNAG-GIDNTNNMPTPDKPN SHEVD_1_PE1009 SHEVD_1_PE1009 EAFYDSSIIYPA-------------VGSDN--SLQERMVYFTKG-GVDN-SAMPVPDSPS SHEVD_1_PE1172 SHEVD_1_PE1172 DAPYVKGAG--G-------------LKVGN--FAKTGKLYYSRG-PTNK-ANLPNPDNAD SHEWM_1_PE1289 SHEWM_1_PE1289 PGAYDSTTTYEP-------------ISSAH--AYQDDKIYFTKGIGIDN-AGMDIPLSPS SHEWM_1_PE1358 SHEWM_1_PE1358 EKPYSSNAG--G-------------ISGDN--LGKQNKLYFTRG-ATAA-EDQPNPSNTS SHONE1_1_PE3211 SHONE1_1_PE3211 VVDYDPDYDYPP-------------LSGSG--YSGD-RIYYTVG-G----GALPTPDTTS MATCH :: CONSENSUS ???Y???????????????????????????????????Y???G?????????P?P????

AERS4_4_PE638 AERS4_4_PE638 SNRRFRDSINACASSKT---------PLGTVGYFQSQVWTYVYSSYRNGVPRQGDWETIS COLP3_1_PE1177 COLP3_1_PE1177 DVRRFTGALNGCFTSIA---------SLAENGTYTDYMREYRSQ--------DNEWQEVR FERBD_1_PE786 FERBD_1_PE786 EERYFSPQINGCESSKRVV--SSGLTVLEQEGYFTSNFRRFQYN--RKASDSGHYWRKLP FERBD_1_PE792 FERBD_1_PE792 ETRYLYPQNNACAASLALHPSSDTLSILQYEGRFTSGVRHFSV--------SYPQWRRLP SHEAM_1_PE1004 SHEAM_1_PE1004 EKRFFTFKRNACASSFE---------FLKEQGVFTGFMRHYVYS--GQ----TGSWEEFP SHEAM_1_PE926 SHEAM_1_PE926 ESRRFNDFLNGCKAARD---------ALNQYGRFTGYIREFITK--GKG---NGTWQPIK SHEB2_1_PE3163 SHEB2_1_PE3163 DKRYFKASLNGCSQSKA---------ALAELGRFTGYIREFTVS--GT----TGIWKELP SHEB5_5_PE1048 SHEB5_5_PE1048 DKRYFKASLNGCSQSKA---------ALAELGRFTGYIREFTAS--GT----TGIWKELP SHEB8_2_PE1107 SHEB8_2_PE1107 DKRYFKASLNGCSQSKT---------ALAELGRFTGYIREFTAS--GT----TGIWKELP SHEB9_1_PE1157 SHEB9_1_PE1157 DKRYFKASLNGCSQSKA---------ALAEFGRFTGYIREFTSS--GT----TGVWKELP SHEDO_1_PE2698 SHEDO_1_PE2698 ESRRFLSDINGCETSWN---------YLNTYGVFTGFFREYSFS--GQ----NGTWQEVP SHEFN_1_PE2860 SHEFN_1_PE2860 STNFITYSKNGCHSSVE---------FLQKFGIYTGYFREYK----------GSKWQEFP SHEHH_1_PE1131 SHEHH_1_PE1131 DSRRFYADNNNCNKAAI---------ALKERGRYTGYLREFKSS--GQ----TGKWVSLA SHELP_1_PE1104 SHELP_1_PE1104 DSRRFYAANNNCHKAAI---------ALQERGRYTGYLREFKSS--GN----TGKWYPLA SHELP_1_PE1176 SHELP_1_PE1176 ERRKFSGTINSCGSSWE---------FLNDYGIFTGFFRKYTFS--GA----NGAWREFG SHEPA_1_PE1088 SHEPA_1_PE1088 ESRRFLSEINGCETSWE---------YLKNYGVFTGFFREYGFS--GQ----NGTWQEVP SHEPC_1_PE1058 SHEPC_1_PE1058 DARRFYLDNNNCNTAAK---------ALVDKGRYTGYLREFSSN--------RNTWNNLA SHEPW_1_PE3541 SHEPW_1_PE3541 SNNYFYNSVNGCKSSKE---------YLADYGVFTGFVREYGFV--GE----NGTWLELP SHESA_2_PE1077 SHESA_2_PE1077 EKRKFKGALNGCESSWE---------YLNRYGTFTGFFREYGFS--GS----SGSWREFS SHESA_2_PE3108 SHESA_2_PE3108 DRRNFSASINGCNQSKA---------ALDQYGRFTGYIREFTSS--GT----TGVWKELP SHESH_1_PE1199 SHESH_1_PE1199 ESRRFEVSNNNCNSAVT---------ALNERGRYTGYIREFKSS--GK----SGEWFSLA SHESM_1_PE1085 SHESM_1_PE1085 EKRKFSGGLNGCESSWE---------YLNRYGTFTGFFREYGFS--GS----SGSWREFS SHESM_1_PE2939 SHESM_1_PE2939 DSRRFYADNNNCNKAKI---------ALESRGRYTGLLREFKAS--GQ----SGKWTALA SHESR_2_PE1146 SHESR_2_PE1146 EKRKFSGGLNGCESSWE---------YLNRYGTFTGFFREYGFS--GS----SGSWREFS SHESR_2_PE3010 SHESR_2_PE3010 ETNRFNLKVNACNEATK---------ALTDYGRFSGHFGEYSTN--GNG---KGTWQLVK SHESW_1_PE3061 SHESW_1_PE3061 DARRFYLDNNNCNTAAK---------ALVDKGRYTGYLREFSSN--------RNTWNNLA SHEVD_1_PE1009 SHEVD_1_PE1009 ESRRFLDEINGCETSWD---------YLNTYGVFTGFFREYSFA--GQ----NGTWQEVP SHEVD_1_PE1172 SHEVD_1_PE1172 EKRQFSGAINGCQSSWQ---------YLNKYGVFTGFFREYRFA--GS----NGTWKEIT SHEWM_1_PE1289 SHEWM_1_PE1289 DSRRFLKDINGCHQSWD---------LIERYGRFTGFVGEYRIK--GK----TGSWGELR SHEWM_1_PE1358 SHEWM_1_PE1358 ETRHFSGVINSCESSWE---------SLHEYGFYTGYFRGYSFT--GS----EGTWKELD SHONE1_1_PE3211 SHONE1_1_PE3211 DRRYFNATINGCNQSKV---------ALDQFGRFTGYIREFTSS--GT----TGVWKEFP MATCH . . : * * : : * : . . : * . CONSENSUS ??R?F????N?C???????????????L???G??TG??RE?????????????G?W????

AERS4_4_PE638 AERS4_4_PE638 GENEDD---I-TIVDCKQDIQNRT-----PANPFSGTL--EVGSVSDGYPVDKTS--NTR COLP3_1_PE1177 COLP3_1_PE1177 NNSGAD---P-VVIDCRNDAYYLQYDENGEIVVGNEGSRNNASGFLSGYPIDGEG--TSQ FERBD_1_PE786 FERBD_1_PE786 SEFKDN-IRDKTVVDCLADLQAGL-----AQNAPN---HPHSDLRGTGFPRNDSK----- FERBD_1_PE792 FERBD_1_PE792 DSIQSELVRKHSIFDCVADLDNAN-----PNNAPA---ALSPLFRGEGFPQNRFM----- SHEAM_1_PE1004 SHEAM_1_PE1004 RSDGAS---I-RMVECFEDIQD--------KNYDN------GSVAKDGLPVDGEG--RRG SHEAM_1_PE926 SHEAM_1_PE926 ENSGAE---RNNPIDCWEDIES--------EYNSNNDDG---SDYKTGYPVGFP----RD SHEB2_1_PE3163 SHEB2_1_PE3163 ETNGTA---I-SVVDCWQDISK--------TDPNN------SSSYSNGFSANGLTTGSGK SHEB5_5_PE1048 SHEB5_5_PE1048 ETNGTA---I-SVVDCWQDISK--------TDPNN------SSSYSNGFAANGLTTGSGK SHEB8_2_PE1107 SHEB8_2_PE1107 ETNGTA---I-SVVDCWQDISK--------TDPNN------SSSYSNGFPANGLTTGSGK SHEB9_1_PE1157 SHEB9_1_PE1157 ETDGRN---I-SVIDCWEDISQ--------VDPNN------SSSYYDGFPANGLTTGSGR SHEDO_1_PE2698 SHEDO_1_PE2698 DNNGAN---V-TVIDCFDDIEA--------KKWKN------APGQPTGFPVDSAG--NKQ SHEFN_1_PE2860 SHEFN_1_PE2860 VSDGSN---I-TKVDCYEDIAVGD-----TTN---------ASGVGAGYPVDDLSD---- SHEHH_1_PE1131 SHEHH_1_PE1131 ENEGFN---QGAIVDCQQDILEFD-----SKNPGRKKQGGGTVAFDNGYPIDTKA----- SHELP_1_PE1104 SHELP_1_PE1104 DNEGFN---RGQVVDCHQDILDSD-----PENPGLEKVGGSSVPFDPGYPIDSKK----- SHELP_1_PE1176 SHELP_1_PE1176 DNNGLN---A-KAVDCYEDIQE--------GNYLN------AKGLTSGLPVDSLG--SPT SHEPA_1_PE1088 SHEPA_1_PE1088 DNNGAN---I-THIDCFDDIEG--------KKWRN------APNQPSGFPIDSAG--NKK SHEPC_1_PE1058 SHEPC_1_PE1058 DNNGFN---QNDIVDCYEDILNGD-----PVNPGKLK----GVAFKNGYPINNKS----- SHEPW_1_PE3541 SHEPW_1_PE3541 DTLGSA---V-SQVDCFEDFETND-----DIKFEN------ATGVDNGLPVDSLG--SKA SHESA_2_PE1077 SHESA_2_PE1077 ELNGSS---I-SAVDCFEDIQE--------NKFGN------AVGEAEGLPVDSLG--TAS SHESA_2_PE3108 SHESA_2_PE3108 ETDGRN---I-TIVDCWEDITK--------VDPNN------SSSYNDGFPANGLTTGSGK SHESH_1_PE1199 SHESH_1_PE1199 ENNGLN---KAALVDCHEDILKPD-----PANPGSIIKGKNVTTFDDGYPINDKN----- SHESM_1_PE1085 SHESM_1_PE1085 ELNGSS---I-SAVDCFEDIQE--------NKFGN------AAGEAQGLPVDSLG--TAS SHESM_1_PE2939 SHESM_1_PE2939 ENEGFN---QGQIVDCYQDIIEGD-----PINPGRYKQGNTYNNFADGYPIDAKA----- SHESR_2_PE1146 SHESR_2_PE1146 ELNGSS---I-SAVDCFEDIQE--------NKFGN------AAGEAQGLPVDSLG--TAS SHESR_2_PE3010 SHESR_2_PE3010 ENSGNE---VQKPIDCWEDILA--------TNSSNNNVQFTDTVSATGYPQNSVVIGSGN SHESW_1_PE3061 SHESW_1_PE3061 DNNGFN---QNDIVDCYEDILNGD-----PVNPGKLK----GVAFKNGYPINNKS----- SHEVD_1_PE1009 SHEVD_1_PE1009 DNNGAN---I-NIIDCFDDIEG--------GKWKN------APGQPNGFPVDSAG--NKK SHEVD_1_PE1172 SHEVD_1_PE1172 GSNANN---A-LAIDCFEDIQD--------SKWRN------AAGADPGLPVDSLG--TPS SHEWM_1_PE1289 SHEWM_1_PE1289 DNSGAN---Y-DTIDCLEDIQEND-----PINAKDKD----GNAHGDGFPVDGMR--QGN SHEWM_1_PE1358 SHEWM_1_PE1358 DTGTEG---V-IGIDCFEDIQD--------EKWAN------AVGVTSGLPVDGRG--SSS SHONE1_1_PE3211 SHONE1_1_PE3211 ETDGRN---I-KVVDCWEDIST--------VDPQN------SSPYSNGFPANGLTTGSGK MATCH .:* * * . . CONSENSUS ???G??????????DC??DI???????????????????????????G?P??????????

AERS4_4_PE638 AERS4_4_PE638 GEWYYTG----------------NANDATSGSNTSVTLYTANYIRWYYGPT---G----- COLP3_1_PE1177 COLP3_1_PE1177 NPIYYDNRVPAQHTN-----------VDWYTSDGLITLYTANYLRWYHGQSTA------- FERBD_1_PE786 FERBD_1_PE786 -TQPYDGTSPSASQSTLDAAAENAMDVTAFGNGDAVTLFTENYLTYLHHHS---S----- FERBD_1_PE792 FERBD_1_PE792 -RSPYDGTSPSASLSERERAADDARNSTQFGQNDVVTLFTENYLTYLHHHS---G----- SHEAM_1_PE1004 SHEAM_1_PE1004 SPSPFFRVSSGSKEA-TKELAMSKAKNTGFGTGRVVTLYTKTYLTWYHSKK---K---Q- SHEAM_1_PE926 SHEAM_1_PE926 GDV----------NN-PWGSDLDSAKNLNWNNGELVTLYTDNYLRWYTLYKNGSLPVPP- SHEB2_1_PE3163 SHEB2_1_PE3163 KKKAYPYFTSSSPGT-SWADALAAANNTDFGVGQPVTLYTDNYLRWYGLSK---AG--KL SHEB5_5_PE1048 SHEB5_5_PE1048 KKKAYPYFTSSSPGT-SWADALAAANNTDFGVGQPVTLYTDNYLRWYGLSK---AG--KL SHEB8_2_PE1107 SHEB8_2_PE1107 KKKAYPYFTSSSPGT-SWADALAAANNTDFGVGQPVTLYTDNYLRWYGLSK---AG--KL SHEB9_1_PE1157 SHEB9_1_PE1157 KKKAYPYFISSSPSS-TWADALAAAKNTDFGVGQPVTFYADNYLRWYWLSK---AG--KL SHEDO_1_PE2698 SHEDO_1_PE2698 NPIRYTPISASSTQA-QIDAAIIKAKQTGFGTGKALTLYTDNYLRWYHGDQ---A---N- SHEFN_1_PE2860 SHEFN_1_PE2860 ------------AYK-NDGNALNNAKLTDFGLGEPITLFTQQYVQWYYNKP---A----- SHEHH_1_PE1131 SHEHH_1_PE1131 ---MYTAGS-------DAAAQAQSVAETDFGEGNPVTLYTSHYLVWYQWVTTTDDG--QN SHELP_1_PE1104 SHELP_1_PE1104 ---MYTDST-------DSSARDYSLENTEFGKGTPVTLYTAHYLVWYQWVTTTEEG--QN SHELP_1_PE1176 SHELP_1_PE1176 TPIMYNNVSSSSSDS-IKKTAKEQAQLTGFGTGRVLTVYTEDYLRWHHNAN---KK--Q- SHEPA_1_PE1088 SHEPA_1_PE1088 NPIRYAEVNASSTTA-EIDAAHTKAQQTGFGTGQSITLYTDNYLRWYHGDQ---E---S- SHEPC_1_PE1058 SHEPC_1_PE1058 ---MYTTGS-------GEADRLSSLSNTQFGSGQPVTLYSAHYLVWHKWATTTEEG--KS SHEPW_1_PE3541 SHEPW_1_PE3541 APIPYTHISSSASSS-DIENAIDAAFLTKFGTGKSVTLYTERYVNWYHGYK---S---S- SHESA_2_PE1077 SHESA_2_PE1077 KPVRYTKASTSSSDS-AKSAAKAKAEKTAFGTGKVVTVYTEDYLNWLHGPK---T---K- SHESA_2_PE3108 SHESA_2_PE3108 KKKAYPYFISSYPSS-TWGDALAAAKNTDFGVGQPVTFYSDNYLRWYWLSK---AG--KL SHESH_1_PE1199 SHESH_1_PE1199 ---MYTSGA-------TDVDRLFSEANTDFGKGSPVTLYTPHYLVWYQWVTKTEEG--QN SHESM_1_PE1085 SHESM_1_PE1085 KPVRYTEASTSSSDN-VKSAAKAKAEKTAFGTGKVVTVYTEDYLNWLHGPK---T---R- SHESM_1_PE2939 SHESM_1_PE2939 ---MYTTAT-------DSDAQKDSLDKTDFGKGSPVTLYTAHYLVWYKWVTTTTEG--QN SHESR_2_PE1146 SHESR_2_PE1146 KPVRYTEASTSSSDN-VKSAAKAKAEKTAFGTGKVVTVYTEDYLNWLHGPK---T---R- SHESR_2_PE3010 SHESR_2_PE3010 NAL----------YS-PWGAK-DSASAANLSGGTLITLYTANYLRWYRHYQKDVASGTTD SHESW_1_PE3061 SHESW_1_PE3061 ---MYTTGS-------GEADRLSSLSNTQFGSGQPVTLYSAHYLVWHKWATTTEEG--KS SHEVD_1_PE1009 SHEVD_1_PE1009 NPVRYTEVDNGSSSS-DFDAAIEKAQLTAFGTGQTITLYTDNYLRWFHGDK---D---L- SHEVD_1_PE1172 SHEVD_1_PE1172 SLINYTVASASSNSK-TKRNATDKAALTGFGTGRVITVYTEDYLRWEHGVK---N---K- SHEWM_1_PE1289 SHEWM_1_PE1289 TPKPYST----------------TGGDTQLGLGEAVTLYTANYLRWHAAAV---AD--AL SHEWM_1_PE1358 SHEWM_1_PE1358 QPRFYTYANGSSTEA-TKQRARERAELTGFGTGRPLTIYTQDYLTWQHGTK---E---K- SHONE1_1_PE3211 SHONE1_1_PE3211 NKKAFPYNTSSSPGT-TWANALAAAKNTGFGVGQPVTFYTDNYLRWYWLSK---EG--RL MATCH . :*.:: *: : CONSENSUS ????Y??????????????????????T?FG?G???T?YT??YL?W??????????????

AERS4_4_PE638 AERS4_4_PE638 -YAVESRLRIAKDAVKSVISS-TPGVDFGLAIFNTNNSTS------TNGGRVVRRILSND COLP3_1_PE1177 COLP3_1_PE1177 -SHLEERLQTAKNSIRDVINS-TPLVEFGLEVFNFNYGDDDT---SGNGGRIAAGIKEM- FERBD_1_PE786 FERBD_1_PE786 -NTKRQRIAIARDTIISLINT-TPGVDFGLQVFNQNTNSG-STIGSNDGGRIVAGIREM- FERBD_1_PE792 FERBD_1_PE792 -SVQRQRITIARETTNSLINT-TTGVDFGLMVFNRNRNSG-NTIGSDDGGRIVEGIREM- SHEAM_1_PE1004 SHEAM_1_PE1004 --VNRTRIDIAKEAVTNVLLT-TPGVDFGLAIFNSNVYEG-----YDDGGRIIAGIKPA- SHEAM_1_PE926 SHEAM_1_PE926 DGEGLTRLEIAKSAISGVISS-IPSVDFGLAIYNLNFPDEG----DSDGGRIVAGIRQR- SHEB2_1_PE3163 SHEB2_1_PE3163 PTVKVSRLEIAKKAISNIISS-TPTVDFGLAVFNYNYPNEG----NRDGGRIVSGITQM- SHEB5_5_PE1048 SHEB5_5_PE1048 PTVKVSRLEIAKKAISNIISS-TPTVDFGLAVFNYNYPNEG----NRDGGRIVSGITQM- SHEB8_2_PE1107 SHEB8_2_PE1107 PTVKVSRLEIAKKAISNIISS-TPTVDFGLAVFNYNYPNEG----NRDGGRIVSGITQM- SHEB9_1_PE1157 SHEB9_1_PE1157 PTVKVSRLEIAKKAISNIISS-TPTVDFGLAVFNYNYPNEG----NRDGGRIVSGITQM- SHEDO_1_PE2698 SHEDO_1_PE2698 --VPKSRLDIAKEVIKNTIVT-TPSVDFGLTVFNINAFSEG----DADGGRIVSGIKTM- SHEFN_1_PE2860 SHEFN_1_PE2860 -ATNTDRITVAKRVLNEVIVN-TPGVDLGLMLFNYNASGSNRSSENKDGGRVVSKINTG- SHEHH_1_PE1131 SHEHH_1_PE1131 SGGTGTRLEVAKSALSNALETLKIPIEASLAVFNLNYPDEY----EIDGGRIVSSMKDI- SHELP_1_PE1104 SHELP_1_PE1104 SGGTGTRLEVAKDALTTALTSLSIPIDAGLAVFNLNYPDEG----DADGGRIVYDIKEM- SHELP_1_PE1176 SHELP_1_PE1176 --EDKTRLELAKDAIKNVILT-TPGVDFGLAIFNMNGPDDTL-YNGRNGGRIIKAIQTL- SHEPA_1_PE1088 SHEPA_1_PE1088 --VPQTRLAIAKEVIKNTIVT-TPSVDFGLAIFNINYPREG----DGDGGRIISGIKVM- SHEPC_1_PE1058 SHEPC_1_PE1058 SGGVGTRLDVAKSALISALESLAIPIDAGLAIFNLNYPNEG----DADGGRIVYDLTEM- SHEPW_1_PE3541 SHEPW_1_PE3541 --SWQTRMNIAKRVMEDTVVT-TPSVDFGLAIFNYNTS--K----RTDGGRIVSGINRL- SHESA_2_PE1077 SHESA_2_PE1077 --VNKTRLALAKDAIESVILT-TPGVDFGLAIFNMNGPYDG----QRDGGRIISGIKPM- SHESA_2_PE3108 SHESA_2_PE3108 PTMKVARLDIAKKAISNIISS-TPTVDFGLAVFNYNYPNEG----NRDGGRIVSGITQM- SHESH_1_PE1199 SHESH_1_PE1199 SGGTGTRLEVAKDALKTALTGLSIPIDAGLAVFNLNYPQEY----EIDGGRIVSAIKEM- SHESM_1_PE1085 SHESM_1_PE1085 --VNKTRLALAKDAIESVILT-TPGVDFGLAIFNMNGPYDG----QRDGGRIISGIKPM- SHESM_1_PE2939 SHESM_1_PE2939 SGGTGSRLDVAKAAIDSALTDLNIDIDAGLAVFNLNYAAEG----DADGGRIVSSIKQL- SHESR_2_PE1146 SHESR_2_PE1146 --VNKTRLALAKDAIESVILT-TPGVDFGLAIFNMNGPYDG----QRDGGRIISGIKPM- SHESR_2_PE3010 SHESR_2_PE3010 PNSQQTRLAIAKDAISSVIST-VPSIDFGLAVYNMNYPREY----DRDGGRIVAGIKSR- SHESW_1_PE3061 SHESW_1_PE3061 SGGVGTRLDVAKSALISALESLAIPIDAGLAIFNLNYPNEG----DADGGRIVYDLTEM- SHEVD_1_PE1009 SHEVD_1_PE1009 --VPKSRLEVAKEVIKNTIVT-TPSVDFGLAIFNLNYRYEG----DRDGGRIVSGIKNM- SHEVD_1_PE1172 SHEVD_1_PE1172 --VTKTRLELAKDAIKNVILT-TPGVDFGLSIFNMNGPGDN----QRDGGRIISGIKNM- SHEWM_1_PE1289 SHEWM_1_PE1289 PTSPQSRLDIAKTAIETVINT-NTSIDFGLALFNMNYPSEG----YRDGGRIVSKIQKM- SHEWM_1_PE1358 SHEWM_1_PE1358 --ANISRLEIAKNAVKSIILT-TPSVDFGLAVFNVNAWNEF----ERDGGRIISGLKEN- SHONE1_1_PE3211 SHONE1_1_PE3211 PTIKVPRIDIAKKAISNIIRS-TPTVDFGLAVFNYNYPNEG----NRDGGRIVSGITQM- MATCH *: *: : :: .* ::* * :***: : CONSENSUS ??????RL??AK??????????????D?GLA?FN?N???????????DGGRI???I????

AERS4_4_PE638 AERS4_4_PE638 DMVGTITAEQNLLNTVEGL--SATTNTPLCETLYEAYRFYGGQPVLYGKQGGTRD----- COLP3_1_PE1177 COLP3_1_PE1177 --TD--DNRANLLNIIANQI-SAEGSTPLCESVYEASQYFAGALVDYGDDDIDVR----- FERBD_1_PE786 FERBD_1_PE786 --TD--SNRNSLTSTVASL--TADTWTPLCESLFEAYRYYSGGAVLGGNKGGSLT----- FERBD_1_PE792 FERBD_1_PE792 --TE--SNRADLVNTVSSL--EATSDTSLCESLFEAYRYFSGGAVLGGNKGGALL----- SHEAM_1_PE1004 SHEAM_1_PE1004 --TA--SNKKDLIEAVDLL--KGTTWTPLCETLYEAYRYFSGGEVWFGDDDPTLK----- SHEAM_1_PE926 SHEAM_1_PE926 --TA--AEKDTMLSTISNL--PAQTNTPLCETLFEAYRYFSGGPITFGHADADYN----- SHEB2_1_PE3163 SHEB2_1_PE3163 --TD--STRASLLTTIDNL--LAKTNTPLCETMYEAYRYFAGKGVKYGHGDTDYG----- SHEB5_5_PE1048 SHEB5_5_PE1048 --TD--STRASLLTTIDNL--LAKTNTPLCETMYEAYRYFAGKGVKYGHGDTDYG----- SHEB8_2_PE1107 SHEB8_2_PE1107 --TD--STRASLLTTIDNL--LAKTNTPLCETMYEAYRYFAGKGVKYGHGDTDYG----- SHEB9_1_PE1157 SHEB9_1_PE1157 --TD--STRASLLTTIDNL--LAKTNTPLCETMYEAYRYFAGKGVKYGHGDTDYG----- SHEDO_1_PE2698 SHEDO_1_PE2698 --TE--ANKLALLNTVAGL--DPETNTPLCETLYEVQQYFGGKTLTFGNKDKKPS----- SHEFN_1_PE2860 SHEFN_1_PE2860 --NI--NNKKALASIVKNTIAIKSNNTPLCETLYEAALYLHGKPLEYGHDTYDSVAATPL SHEHH_1_PE1131 SHEHH_1_PE1131 --RQNTANLASFISLINGM--PAQTNTPLCETLYEAHQYFSGGAVIYGNKDSNAQ----- SHELP_1_PE1104 SHELP_1_PE1104 --TS--TNQNSLISLINGM--PAQTNTPLCETLYEAYQYFSGGPVTFGNDDKNAQ----- SHELP_1_PE1176 SHELP_1_PE1176 --TP--GQKKTLLSGVKDI--EYGWNTPLCETLYEAYRYFAGKSVEFGDDDKDYT----- SHEPA_1_PE1088 SHEPA_1_PE1088 --NE--ANKISLLETIDNL--PASTNTPLCETLYEAYRYFSGKSVYFGDDDYNVG----- SHEPC_1_PE1058 SHEPC_1_PE1058 --NS--INKVNLTSLIKNM--PAKTNTPLCETLYEAYQYFSGGQVTFGNKDKNGT----- SHEPW_1_PE3541 SHEPW_1_PE3541 --ST--GDKISLVDKINDL--NAETNTPLCETLYEAYRYFSGSAVHFAKEAGS------- SHESA_2_PE1077 SHESA_2_PE1077 --SA--AAKIDLLKGINDI--NYAQNTPLCETLYEAYRYFGGQSQYFGDDDSDYH----- SHESA_2_PE3108 SHESA_2_PE3108 --TD--AARDSLLLTIDKL--PAKTNTPLCETMYEAYRYFAGQGVKYGHGDTDYG----- SHESH_1_PE1199 SHESH_1_PE1199 --TP--TNESTLISLINGM--PAQTNTPLCETLYEAHQYFSGGAVTFGNKDRNGQ----- SHESM_1_PE1085 SHESM_1_PE1085 --SA--AAKIDLLKGVNDI--NYAQNTPLCETLYEAYRYFGGQSQYFGDDDSDYD----- SHESM_1_PE2939 SHESM_1_PE2939 --TS--ANQTSLMSLINGM--PAQTNTPLCETLYEAHQYFSGGDVTFGNKDANAK----- SHESR_2_PE1146 SHESR_2_PE1146 --SA--AAKIDLLKGVNDI--NYAQNTPLCETLYEAYRYFGGQSQYFGDDDSDYD----- SHESR_2_PE3010 SHESR_2_PE3010 --TA--AEKTTLINTITQL--PADTNTPLCETLFEAYSYFSGGKIQFGHSDSNYK----- SHESW_1_PE3061 SHESW_1_PE3061 --NS--INKVNLTSLIKNM--PAKTNTPLCETLYEAYQYFSGGQVTFGNKDKNGT----- SHEVD_1_PE1009 SHEVD_1_PE1009 --TE--ANKVSLLETIENL--PASTNTPLCETLYEAYRYFSGKGVYYGNDDSNYS----- SHEVD_1_PE1172 SHEVD_1_PE1172 --SS--KGKIDLLTSVQSI--TYAQNTPLCETLYEAYRYFSGQSVLFGDDDSDYI----- SHEWM_1_PE1289 SHEWM_1_PE1289 --SP--ANKTALLSTIDGI--PADTNTPLCETLFEAYKYFSGKPVLYGKKDSDYS----- SHEWM_1_PE1358 SHEWM_1_PE1358 --TS--GVKSDLIEVIGDI--QGKTNTPLCETLYEAYRYFSGLSVDFAYKNTDLP----- SHONE1_1_PE3211 SHONE1_1_PE3211 --TD--TSRASLLSTIDGL--PAKTNTPLCETMYEAYRYFAGKGVVFGHADTDYG----- MATCH : : *.***:::*. : * . CONSENSUS ???????????L?????????????NTPLCET?YEAY?YF?G?????G??D?????????

AERS4_4_PE638 AERS4_4_PE638 -----K----------------------------LAEDPEGTYTSPYD--KCS-NNGYVI COLP3_1_PE1177 COLP3_1_PE1177 -----DYN----Y---------SKNIPPMATDITEVVDGHNVYKTPFE--DCASSVANII FERBD_1_PE786 FERBD_1_PE786 --------------------------PAAD----SSVVSGSNYISPMS--SCQ-PQSYVI FERBD_1_PE792 FERBD_1_PE792 --------------------------PAAD----DSVVSGDNYISPLS--SCQ-ANSYVL SHEAM_1_PE1004 SHEAM_1_PE1004 -----PYR---------------------DK--DAI-DANSRYKSPFK--TCQ-NRAYIV SHEAM_1_PE926 SHEAM_1_PE926 -----G--KDIKYSS---------NKPMYD----ASIENGANYITPLS--ECN-KVAHII SHEB2_1_PE3163 SHEB2_1_PE3163 -----SYV---------------GNKPPYD----SLVEKGGSYESPFK--VCT-DIAYVI SHEB5_5_PE1048 SHEB5_5_PE1048 -----SYV---------------GNNPPYD----SLVEKGGSYESPFK--VCT-DIAYVI SHEB8_2_PE1107 SHEB8_2_PE1107 -----SYV---------------GNKPPYD----SLVEKGGSYESPFK--VCT-DIAYVI SHEB9_1_PE1157 SHEB9_1_PE1157 -----SYV---------------GNKPPYD----SLVEKGGSYESPFK--VCT-DIAYVI SHEDO_1_PE2698 SHEDO_1_PE2698 -----GYS--------YT----P-NTPPRDT----SIEQSGKYISPFK--ECQ-NLAYVV SHEFN_1_PE2860 SHEFN_1_PE2860 NKTWKWVKKWNGWIEESTPVNPAQYNPGYD----ATAESVDGYISPFIGKKCG-SNASII SHEHH_1_PE1131 SHEHH_1_PE1131 -----GHYKIDGYVP---------NSP-------PSIQMSGSYTSPFK--KCP-DTAYVI SHELP_1_PE1104 SHELP_1_PE1104 -----GSYKIDGYIP---------NSP-------PSILTGGNYTTPFK--KCP-DTAYII SHELP_1_PE1176 SHELP_1_PE1176 ------YESWGRWVT-YR----ANKNDSLDK--DALVKGTNTYQSPFK--KCQ-NNAYIV SHEPA_1_PE1088 SHEPA_1_PE1088 -----NLG--------YK----K-NIPPRDT--HKDVESDGKYVSPFK--ECQ-NRAYVV SHEPC_1_PE1058 SHEPC_1_PE1058 -----GNNKIDGYTP---------NNP-------PSILTSGSYTTPFK--KCP-DTAYII SHEPW_1_PE3541 SHEPW_1_PE3541 ------------------------MTPTRD----KSIESNGNYVSPFKSSQCS-NRSYVV SHESA_2_PE1077 SHESA_2_PE1077 -----YYDQWGRYQGTYQ----AKRNPFTDP--EALVVGTNNYNSPFK--RCQ-NEAYII SHESA_2_PE3108 SHESA_2_PE3108 -----SYV---------------GNRPPYD----TSVEKGGAYSSPFK--VCT-DIAYVI SHESH_1_PE1199 SHESH_1_PE1199 -----GYYKIDGYVP---------NNP-------PSIISSGSYTTPFK--KCP-DTAYII SHESM_1_PE1085 SHESM_1_PE1085 -----YFDRWGRYLGTYQ----ASRNSFTDP--EALVVGTNNYNSPFK--RCQ-NEAYII SHESM_1_PE2939 SHESM_1_PE2939 -----GNDKIDGYVP---------NSP-------PSILSTGKYTTPFK--KCP-DTAYII SHESR_2_PE1146 SHESR_2_PE1146 -----YFDRWGRYLGTYQ----ASRNSFTDP--EALVVGTNNYNSPFK--RCQ-NEAYII SHESR_2_PE3010 SHESR_2_PE3010 -----DASNKIDYTA---------NQPKYD----TSIESNGSYISPLS--KCN-KVAHII SHESW_1_PE3061 SHESW_1_PE3061 -----GNNKIDGYTP---------NNP-------PSILTSGSYTTPFK--KCP-DTAYII SHEVD_1_PE1009 SHEVD_1_PE1009 -----NW---------YR----A-NRPPRDT----SIEDNGKYISPFK--ECQ-NRAYVV SHEVD_1_PE1172 SHEVD_1_PE1172 -----SYDRWGRYRGIYK----SNRNSPLDP--DILDA--GVYSSPLK--KCQ-DKAYIV SHEWM_1_PE1289 SHEWM_1_PE1289 -----SWY--------------DGNKPPRDT----SAESGLNYSSPFR--VCP-DIAYVI SHEWM_1_PE1358 SHEWM_1_PE1358 -----GA-------GYY-----VSQQP--QM--DASVAKSGIYESPFK--KCQ-NNASVV SHONE1_1_PE3211 SHONE1_1_PE3211 -----SYV---------------GNRPPYD----NSVETNGTYVSPFK--VCT-DIAYVI MATCH * :* * . :: CONSENSUS ??????????????????????????P???????????????Y??PF????C????AY??

AERS4_4_PE638 AERS4_4_PE638 YVTDGAPTSDTDADSAVKALMDSLSTDERA----AYG--------------------STV COLP3_1_PE1177 COLP3_1_PE1177 LITDGAPQHDFAADSKITAMVTTVQRANDTDGNPVYESLTFTGAHTEALTDETNTFDGSA FERBD_1_PE786 FERBD_1_PE786 LITDGEPTRDGSYNSLIESELGLGSDDK-------------------------------- FERBD_1_PE792 FERBD_1_PE792 LMTDGSPYRDNSLNTLIESELGLTAADK-------------------------------- SHEAM_1_PE1004 SHEAM_1_PE1004 YVTDGEPTRDSNANQLVYDLTGGV--DAYT------------------------------ SHEAM_1_PE926 SHEAM_1_PE926 YITDGAPVLDESANDYIKELGGEPYEYK-------------------------------- SHEB2_1_PE3163 SHEB2_1_PE3163 YVTDGTPTVDKNANNDVISLTASGSKEGNY------------------------------ SHEB5_5_PE1048 SHEB5_5_PE1048 YVTDGTPTVDKNANNDVISLTASGSKEGNY------------------------------ SHEB8_2_PE1107 SHEB8_2_PE1107 YVTDGTPTVDKNANNDVISLTASGSKEGNY------------------------------ SHEB9_1_PE1157 SHEB9_1_PE1157 YVTDGAPTVDKSANNDVISLTSTGSKDGDY------------------------------ SHEDO_1_PE2698 SHEDO_1_PE2698 YITDGVPTLDQNANNLVKALPNAD-QTAYK------------------------------ SHEFN_1_PE2860 SHEFN_1_PE2860 YITDGAPTSDTDAQGKVKSLLGLASTTTDA---------------------------DVP SHEHH_1_PE1131 SHEHH_1_PE1131 YITDGAPTLDSAADGYIKTLTDNAA-ETGN-----YG--------------------PFD SHELP_1_PE1104 SHELP_1_PE1104 YITDGAPTIDSNADSAIISLASSAE-NTAN-----YS--------------------GFD SHELP_1_PE1176 SHELP_1_PE1176 FITDGEPTLDSAADVEVTKLTGGV--DKHS------------------------------ SHEPA_1_PE1088 SHEPA_1_PE1088 YITDGVPTLDNNADQKVLELPGVSSSDKFI------------------------------ SHEPC_1_PE1058 SHEPC_1_PE1058 YITDGAPTLDKSADTLINGLVANAKNQAAN-----YA--------------------AFS SHEPW_1_PE3541 SHEPW_1_PE3541 YITDGSPTQDSAANTKVSKMSGYKSSE--------------------------------- SHESA_2_PE1077 SHESA_2_PE1077 YITDGEPTLDNAADGLVEQLTKGV--GKHT------------------------------ SHESA_2_PE3108 SHESA_2_PE3108 YVTDGSPTVDKSANNDVISLTSTGSKDGDY------------------------------ SHESH_1_PE1199 SHESH_1_PE1199 YITDGAPTLDRAADGAIAGLTASAA-NAAN-----YA--------------------PFT SHESM_1_PE1085 SHESM_1_PE1085 YITDGEPTLDNAADGLVEQLTKGV--GKHT------------------------------ SHESM_1_PE2939 SHESM_1_PE2939 YITDGAPTLDHSADAKVLDLTGKAE-VAAD-----YS--------------------GFE SHESR_2_PE1146 SHESR_2_PE1146 YITDGEPTLDNAADGLVEQLTKGV--GKHT------------------------------ SHESR_2_PE3010 SHESR_2_PE3010 YITDGAPVLDDAANDLIKGLGGTPYTYN-------------------------------- SHESW_1_PE3061 SHESW_1_PE3061 YITDGAPTLDKSADTLINGLVANAKNQAAN-----YA--------------------AFS SHEVD_1_PE1009 SHEVD_1_PE1009 YITDGVPTVDQSANSKVKALPGVSSSDKFV------------------------------ SHEVD_1_PE1172 SHEVD_1_PE1172 YITDGEPTVDSAANHAIQSLTGGV--DKHT------------------------------ SHEWM_1_PE1289 SHEWM_1_PE1289 YITDGVPTQDTFADTDITTLTASGVTEKADD-KVVAP--------------------DYS SHEWM_1_PE1358 SHEWM_1_PE1358 IITDGVPTKDAAANGFIDTLTGGA--DKYG------------------------------ SHONE1_1_PE3211 SHONE1_1_PE3211 YVTDGSPTVDGSANNNVKTLTAAASKSGNY------------------------------ MATCH :*** * * : : CONSENSUS Y?TDG?PT?D??A??????L????????????????????????????????????????

AERS4_4_PE638 AERS4_4_PE638 --GYGSGSAKSYLAAMAGYMKNKDVNTS---------SPGKQTVTTFTVGFGDEAIS-GA COLP3_1_PE1177 COLP3_1_PE1177 YPSGNRTSDDSYLPALASWMSEYDINLN---------RAGKQTVVTHTIGFSNGAIA--A FERBD_1_PE786 FERBD_1_PE786 -------VDSNYLAGVAGWMYNNDVNET---------LQGRQRVATYTIGFSEGATG--A FERBD_1_PE792 FERBD_1_PE792 -------HNGSHLPGVAEWMYQNDMNTS---------ATGHQKVVTYTVGFSQGAVD--A SHEAM_1_PE1004 SHEAM_1_PE1004 ---S---SPASYLSSLSSWMNTQDVNPN---------MTGKQSVSTYTIGFSQGAAS--A SHEAM_1_PE926 SHEAM_1_PE926 AASGDQEAKVSYLPALAEYMFANDLLPD---------VENKQRVVTHTIGFSLGEDSE-A SHEB2_1_PE3163 SHEB2_1_PE3163 SSFSKNLDTASYLPALASYMFNNDLINKLD----SSNTEQMQNVRTYTIGFSKGAED--A SHEB5_5_PE1048 SHEB5_5_PE1048 SSFSKNLDTASYLPALASYMFNNDLINKLD----SSNTEQVQNVRTYTIGFSKGAED--A SHEB8_2_PE1107 SHEB8_2_PE1107 SSFSKNLDTASYLPALASYMFNNDLINKLD----SSNTEQVQNVRTYTIGFSKGAED--A SHEB9_1_PE1157 SHEB9_1_PE1157 SSFSKNLDTASYLPALASYMFNNDLINKLD----SSNTEQMQNVRTYTIGFSKGAED--A SHEDO_1_PE2698 SHEDO_1_PE2698 ---NTNPNFSSYLPNLAQWMNNNDVNAN---------LVGEQKVKTFTIGFSDGAAD--A SHEFN_1_PE2860 SHEFN_1_PE2860 GSESLGNDNYSLLPPLAHWLATNDVNPN---------SEGDQVVNTYTIGFSADAPV--- SHEHH_1_PE1131 SHEHH_1_PE1131 FTNTRGNTQTSYLPALASYMYNNDLVVG---NKDSSGVDNKQNVMLSTIGFSDGADA--A SHELP_1_PE1104 SHELP_1_PE1104 FVNSWGDTETSYLPALAAYMYNNDMVKG---VKDANGIDNKQNVRLFTIGFSEGADV--A SHELP_1_PE1176 SHELP_1_PE1176 ---T------SYMSALSSWMYRKDVNPN---------MDGDQHVITHTIGFSEGAKN--A SHEPA_1_PE1088 SHEPA_1_PE1088 ---NTSPSFTSYLPALAGWMNTNDVNTSE-------AYPDDQNVTTFTIGFSEGADA--A SHEPC_1_PE1058 SHEPC_1_PE1058 FTNAGNKTETSYMPALAAYMYNNDIVIG---NKDSLGIDNKQNIRVFTIGFSDGADE--A SHEPW_1_PE3541 SHEPW_1_PE3541 ------RVDGSYLPALASIMHRQDVNPS---------LAGEQFVTTYTIGFSDGAAD--A SHESA_2_PE1077 SHESA_2_PE1077 ---S---SPVSYLSALSGWMRNEDVNPN---------SAGKQTVRTFTIGFSEGAAS--A SHESA_2_PE3108 SHESA_2_PE3108 SSFSKNLDTPSYLPALASYMFNNDLINKLD----SSNTEQMQNVRTYTIGFSKGAED--A SHESH_1_PE1199 SHESH_1_PE1199 FTNTRGDEETSYMPALAAYMYNNDLVKG---VKDASGVDNQQNVRLFTIGFSDGADA--A SHESM_1_PE1085 SHESM_1_PE1085 ---S---RPVSYLSALSGWMRNEDVNPN---------SAGKQTVRTFTIGFSEGAAS--A SHESM_1_PE2939 SHESM_1_PE2939 FTNDKGEKENSYLPALAAYMANNDLVKG---VTDATGIDNKQNVRTFTIGFTDGADV--A SHESR_2_PE1146 SHESR_2_PE1146 ---S---RPVSYLSALSGWMRNEDVNPN---------SVGKQTVRTFTIGFSEGAAN--A SHESR_2_PE3010 SHESR_2_PE3010 SS-----GKSSYLPALAGYMFNHDMS-S---------ADGFQRVITHTIGFSLGEDKDAA SHESW_1_PE3061 SHESW_1_PE3061 FTNAGNKTETSYMPALAAYMYNNDIVIG---NKDSLGVDNKQNIRVFTIGFSDGADE--A SHEVD_1_PE1009 SHEVD_1_PE1009 ---NSSPNFTSYLPALAGWMNTNDVNTNA-------AFPEEQNVTTFTIGFSDGADD--A SHEVD_1_PE1172 SHEVD_1_PE1172 ---A---YPVSYLSAMSSWMNNHDVNPK---------EPGVQHVSTFTIGFSEGAAS--A SHEWM_1_PE1289 SHEWM_1_PE1289 VFSDPGLSSPSYLPALASYLYHNDLVTSPETLSDGSTREHMQTVKTFTIGFSSGAED--A SHEWM_1_PE1358 SHEWM_1_PE1358 ---SAATGDLNYLSAMSSWMNKYDLNTS---------EPGEQTVSTHTIGFSKGAAS--A SHONE1_1_PE3211 SHONE1_1_PE3211 SSFSQGLSTPSYLPALASYMFNNDLINKPD----SSNTEQMQNVRTYTIGFSKGADD--A MATCH . :. :: : *: * : *:** CONSENSUS ??????????SYL?AL???M???D?????????????????Q?V?T?TIGFS?GA????A

AERS4_4_PE638 AERS4_4_PE638 GNLLAETARRGGGQ------------YYPAVSAEALTQALRSSLLAILRINTSLVSPAIT COLP3_1_PE1177 COLP3_1_PE1177 RGLLEETARRGKGQ------------YVDADTGTSLIAALENILDNLPEANDSLTSASVS FERBD_1_PE786 FERBD_1_PE786 AGLLEQTALQGGGS------------YYAAADALALQSSLQQIFSEILAVNASFTSPSIA FERBD_1_PE792 FERBD_1_PE792 AELLEQTAHRGGGL------------YYPANDAAALQSSLQQIVSEILSVNTSFTSPSVA SHEAM_1_PE1004 SHEAM_1_PE1004 AGLLRHTAEKGGGK------------YYDATNVDDLQKSLMQVFKNILEKNASFTAPAVA SHEAM_1_PE926 SHEAM_1_PE926 EPLLVETASRSYLMTS--EGKKVFGTYRSADDVAGLQEAISNIIDSIPQTGQRFSAPGVA SHEB2_1_PE3163 SHEB2_1_PE3163 APLLAETAKRGGGL------------YFAAQNSLELQNALNDALSNILNIDSSFTSPSIA SHEB5_5_PE1048 SHEB5_5_PE1048 APLLAETAKRGGGL------------YFAAQNSLELQNALNDALSNILNIDSSFTSPSIA SHEB8_2_PE1107 SHEB8_2_PE1107 APLLAETAKRGGGL------------YFAAQNSLELQNALNDALSNILNIDSSFTSPSIA SHEB9_1_PE1157 SHEB9_1_PE1157 APLLAETAKRGGGL------------YFAAQNSIELQNALNDALSNILNIDSSFTSPSIA SHEDO_1_PE2698 SHEDO_1_PE2698 APLLIKTAELGGGK------------YFAAKGAAQLQAALQQVFTDILEVNASFTSPSIA SHEFN_1_PE2860 SHEFN_1_PE2860 -DILISTAALGGGK------------YYSALDPAELQASLISAIAAIELDSSSFSSPSVV SHEHH_1_PE1131 SHEHH_1_PE1131 ATLLEEAAYRGGYARR---DNGVSKGYYVAKTGLALETALEDALKSILSVDSSFTSPSIA SHELP_1_PE1104 SHELP_1_PE1104 AKLLEEAAFRGGNPRD---DSGVSKGYYVAKNGLDLVAAMDDALKSILSIDSSFTSPSIA SHELP_1_PE1176 SHELP_1_PE1176 EDLLKKVASKGGGS------------YFDATDATKLQGSIQQAVNEVLANSASFTSPSVA SHEPA_1_PE1088 SHEPA_1_PE1088 AALLKKTAEKGGGE------------YFHAADASALQAALQQVFSQILEVNASFTSPSIA SHEPC_1_PE1058 SHEPC_1_PE1058 AALLEETAFRGGNPRG---SNNISKGYYVAKNGLDLVSALEDALKSSLTIDSSFTSPSIA SHEPW_1_PE3541 SHEPW_1_PE3541 EPILKKTAELSGGT------------YFPAKNATQLQSALQQVFSQILEVNASFTSPSIA SHESA_2_PE1077 SHESA_2_PE1077 EHLLKQTAENGGGK------------YFDATDASKLRSSLQTALNNILEKNASFTSPSVA SHESA_2_PE3108 SHESA_2_PE3108 APLLAETAKRGGGL------------YFAAQNSLELQNALNDALSNILNIDSSFTSPSIA SHESH_1_PE1199 SHESH_1_PE1199 ADLLEEAAFRGGNPRV----NGVSKGYYVAKNGLDLVTAMDDALKSILSIDSSFTSPSIA SHESM_1_PE1085 SHESM_1_PE1085 EHLLKQTAENGGGK------------YFDATDASKLRSSLQTALNNILEKNASFTSPSVA SHESM_1_PE2939 SHESM_1_PE2939 AKLLEETAFRGGNPRELKNGNLVSKGYYRAATGLDLIQALDDALKSILSIDSSFTSPSIA SHESR_2_PE1146 SHESR_2_PE1146 EHLLKQTAENGGGK------------YFDATDASKLRSSLQTALNNILEKNASFTSPSVA SHESR_2_PE3010 SHESR_2_PE3010 EPLLIETAKRSVD-----SKGEVWGTYSPADNTVELVAAITKLVAEINKTGQRFSAPGVA SHESW_1_PE3061 SHESW_1_PE3061 AALLEETAFRGGNPRG---SNNISKGYYVAKNGLDLVSALEDALKSILTIDSSFTSPSIA SHEVD_1_PE1009 SHEVD_1_PE1009 APLLTRTAELGGGE------------YYSAKSATQLQAALSQVFSQILEVNASFTSPSIA SHEVD_1_PE1172 SHEVD_1_PE1172 ASLLKKTAAVGGGS------------YFDATNAKLLQGSLQQAVNKILEKNASFTSPAVA SHEWM_1_PE1289 SHEWM_1_PE1289 EALLKETARRGGNKVD---DNGVNTGYFQATGGLGLVAAMNDALLSIMETDASFTSPSIA SHEWM_1_PE1358 SHEWM_1_PE1358 AALLKKTAEVGGGR------------YFDATNANLLQGSLQQVVSEALDTNSSFTSPAVA SHONE1_1_PE3211 SHONE1_1_PE3211 APLLAETAKRGGGL------------YFAAQNSLELQNALNDALSNILNIDSSFTSPSIA MATCH :* .* . * * * :: . . : :..: CONSENSUS ??LL??TA??GG??????????????Y??A?????L???L??????IL????SFTSPS?A

AERS4_4_PE638 AERS4_4_PE638 TNNFDRTRSLNNIYYAMFEPDTGPRWKGNLKKLTLSGDGYV---ADVNGL-----PAIKA COLP3_1_PE1177 COLP3_1_PE1177 ANSYLNNQTLDSVYYGMFEPSMGARWQGNLKKYKVVNEKITGVGADGNGDGVDVICDVDG FERBD_1_PE786 FERBD_1_PE786 ANSFDRTQTLDAVYYAMFLPSDRPRWMGNLKKLKITSSGSV---VDQSSV-----SAIDA FERBD_1_PE792 FERBD_1_PE792 ANSFDRTQTLDSLYYAMFLPSDRPRWMGNLKKLKVNSEGLV---VDQNGV-----LAINA SHEAM_1_PE1004 SHEAM_1_PE1004 SNNFNRIRTFDSVYYSMFLPNRGPRWSGNLKKFKVTDSGDI---IDASKA-----KVIDG SHEAM_1_PE926 SHEAM_1_PE926 FSNADPTRTLDSAYYALFRPQQSPKWAGNLKKLKVNSSGTL---VDSTGK-----PAIDS SHEB2_1_PE3163 SHEB2_1_PE3163 SNNFDRTQTFDAAYYAMFLPGKGPRWSGNLKKLKVTADGTL---VDSKGN-----AAIAD SHEB5_5_PE1048 SHEB5_5_PE1048 SNNFDRTQTFDAAYYAMFLPGKGPRWSGNLKKLKVTADGTL---VDSKGN-----AAIAD SHEB8_2_PE1107 SHEB8_2_PE1107 SNNFDRTQTFDAAYYAMFLPGKGPRWSGNLKKLKVTADGTL---VDSKGN-----AAIAD SHEB9_1_PE1157 SHEB9_1_PE1157 SNNFDRTQTFDAAYYAMFLPGKGPRWSGNLKKLKVTADGTL---VDSKGS-----AAIAD SHEDO_1_PE2698 SHEDO_1_PE2698 SNNFDRTETFDSVYYAMFLPNRGPRWSGNLKKFKVTSGGKI---IDSKSV-----EAIGS SHEFN_1_PE2860 SHEFN_1_PE2860 ---LDKTQTGNSAYFAMFLPGKGPRWSGNLKKFKISSSGEV---LDKNNI-----KAFSS SHEHH_1_PE1131 SHEHH_1_PE1131 SNNFDKTQTYNSAYFAMFLPGDGPRWSGNLKKLKVTSAGDI---VGPGGT----SKAIDA SHELP_1_PE1104 SHELP_1_PE1104 SNNFDKTQTYNSAYFAMFLPGKGPRWSGNLKKLKVNSSGEI---VGPGGS----SKAIDS SHELP_1_PE1176 SHELP_1_PE1176 SNNFNRTQTFNYAYYSMFLPDRGPRWTGNIKKFRVAADGTV---LDAEGK-----IALGD SHEPA_1_PE1088 SHEPA_1_PE1088 SNNFDRTRTFDSVYYAMFLPNKGPRWSGNLKKFRVTGDGDI---VDKSGA-----NALGN SHEPC_1_PE1058 SHEPC_1_PE1058 SNNFDKTQTYNSAYYAMFLPGNGPRWSGNLKKLKVNAAGEI---VGPGGN----NKAIDS SHEPW_1_PE3541 SHEPW_1_PE3541 SNNFDRTQTFDSVYYAMFLPNKGPRWMGNIKKFKVTGSGDI---VDKNGN-----AAIGS SHESA_2_PE1077 SHESA_2_PE1077 SNNFNRTQTFDSAYYSMFLPNKGPRWLGNIKKFKVTSSGDV---VDSKGN-----NAIGE SHESA_2_PE3108 SHESA_2_PE3108 SNNFDRTQTFDAAYYAMFLPGKGPRWSGNLKKLKVTGDGTL---VDSQGN-----AAIAD SHESH_1_PE1199 SHESH_1_PE1199 SNNFDKTQTYNSAYFAMFLPGKGPRWSGNLKKLKVNGSGDI---VGPGGT----ANAIDS SHESM_1_PE1085 SHESM_1_PE1085 SNNFNRTQTFDSAYYSMFLPNKGPRWLGNIKKFKVTSSGDV---VDSKGN-----NAIGE SHESM_1_PE2939 SHESM_1_PE2939 SNNFDKTQTYNSAYFAMFLPGEGPRWSGNLKKLKVNSAGEI---VGPGGD----TNAIDS SHESR_2_PE1146 SHESR_2_PE1146 SNNFNRTQTFDSAYYSMFLPNKGPRWLGNIKKFKVTSSGDV---VDSKGN-----NAIGE SHESR_2_PE3010 SHESR_2_PE3010 FSSADPTRTLESAYYALFEPSQSPKWTGNLKKLKVNSSGVL---VDKNNK-----AAIDS SHESW_1_PE3061 SHESW_1_PE3061 SNNFDKTQTYNSAYYAMFLPGNGPRWSGNLKKLKVNAAGEI---VGPGGN----NKAIDS SHEVD_1_PE1009 SHEVD_1_PE1009 SNNFDRTQTFDSVYYAMFLPNKGPRWMGNLKKFRVTGSGDI---VDKNGT-----LAIGT SHEVD_1_PE1172 SHEVD_1_PE1172 SNNFNRTQSFEYAYYSMFLPNKGPRWTGNIKKFKVTGSGDI---IDQNGK-----NAIGG SHEWM_1_PE1289 SHEWM_1_PE1289 SNNFDRTQTFDAAYYAMFLPGRGPRWSGNLKKLKVTSGGVL---VDKSGG-----VAIGD SHEWM_1_PE1358 SHEWM_1_PE1358 SNNFNRTQSFEYAYYSIFLPNKGPTWLGNLKKYRVTGKGEV---VDKAGN-----PAIGL SHONE1_1_PE3211 SHONE1_1_PE3211 SNNFDRTQTFDAAYYAMFLPGKGPRWSGNLKKLRVTADGTL---VDGEGN-----AAIAD MATCH .: : *:.:* * . * **:** : . . CONSENSUS ?NNF??TQT????YY?MFLP??GPRW?GNLKK?KV???G??????D??G???????AI??

AERS4_4_PE638 AERS4_4_PE638 DGSILEQAQTYWSS---------ERD------------GNLVAKGGVQAMLAEK------ COLP3_1_PE1177 COLP3_1_PE1177 SSSFCDTARSFWST---------EAD------------GNVVGQGGVLTWFNSHIP---- FERBD_1_PE786 FERBD_1_PE786 QGNISDRACTYWTSAQTCSGASSGGD------------GNDVTVGGALEQLGLQ------ FERBD_1_PE792 FERBD_1_PE792 RGNISDGACTYWTRAQTCSATDGGGD------------GNDVTVGGALEQLGVQ------ SHEAM_1_PE1004 SHEAM_1_PE1004 DGNIAKTACSHWSSSADCSA----GD------------GNDVRRGGAAGMLQRM-Q---- SHEAM_1_PE926 SHEAM_1_PE926 SGGIAESSCSLWSN---CTG---GND------------GNDVVLGGAARTIVP------- SHEB2_1_PE3163 SHEB2_1_PE3163 NGNIKDGACTIWSN---CDA---QKD------------GNKVEVGGVAAQIRTQ------ SHEB5_5_PE1048 SHEB5_5_PE1048 NGNIKDGACTIWSN---CDA---QKD------------GNKVEVGGVAAQIRTQ------ SHEB8_2_PE1107 SHEB8_2_PE1107 NGNIKDGACTIWSN---CDA---QKD------------GNKVEVGGVAAQIRTQ------ SHEB9_1_PE1157 SHEB9_1_PE1157 NGNIKDGACTIWSN---CDA---QKD------------GNKVEVGGVAAQIRTQ------ SHEDO_1_PE2698 SHEDO_1_PE2698 DGNIKSSACSFWTSSAICASSSDGGD------------GNDVTIGGTAEALRQT------ SHEFN_1_PE2860 SHEFN_1_PE2860 DGRIAKDACSLWATDSDCAAG--DYE------------GYDVNDGGVAAALRYNYQYASG SHEHH_1_PE1131 SHEHH_1_PE1131 AGNISASTCTYWNI---CTSS--NAD------------GNKVNSGGVLPALRKA------ SHELP_1_PE1104 SHELP_1_PE1104 NGNIAASTCTYWNT---CPAN--NID------------GNKVNSGGVLPILRST------ SHELP_1_PE1176 SHELP_1_PE1176 DGNIKDSACSYWTPKKLCG------D------------GNDVRKGGVLSAMQSA------ SHEPA_1_PE1088 SHEPA_1_PE1088 DGNLVSSACSYWTSDSTCASASDGGD------------GNDVRVGGAADSIGYI------ SHEPC_1_PE1058 SHEPC_1_PE1058 NGNIANDVCTYWNT---CSES---ND------------GNKVLFGGVLPSLRAK------ SHEPW_1_PE3541 SHEPW_1_PE3541 DGNLSNSACSYWTPNSVCSASSGGGD------------GNDVRVGGVAHELRSA------ SHESA_2_PE1077 SHESA_2_PE1077 DGNIKAEACSYWTSAEECGA---SGD------------GNDVKRGGVLGAMQQA------ SHESA_2_PE3108 SHESA_2_PE3108 NGNIKDTACTIWSD---CAS---QKD------------GNKVEVGGASAQIKSQ------ SHESH_1_PE1199 SHESH_1_PE1199 NGNIASTTCTFWNT---CSGA--NND------------GNKVTAGGVLPALRTA------ SHESM_1_PE1085 SHESM_1_PE1085 DGNIKAEACSYWTSAEECGA---SGD------------GNDVKRGGVLGAMQQA------ SHESM_1_PE2939 SHESM_1_PE2939 NGNISASTCTYWNV---CAAG--SPD------------GNKVNSGGVLPILRES------ SHESR_2_PE1146 SHESR_2_PE1146 DGNIKAEACSYWTSAEECGA---SGD------------GNDVKRGGVLGAMQQA------ SHESR_2_PE3010 SHESR_2_PE3010 SGGITSSACTIWST---CST---DGDVGYVDESGIIDGGNVVSAGGAARQIDP------- SHESW_1_PE3061 SHESW_1_PE3061 NGNIANDVCTYWNT---CSES---ND------------GNKVLFGGVLPSLRAK------ SHEVD_1_PE1009 SHEVD_1_PE1009 DGNLKSSACSYWTSNSVCSSSSDGGD------------GNDVRTGGLAHVLRTG------ SHEVD_1_PE1172 SHEVD_1_PE1172 DGNIKAEACSYWTPKSVCDA---GGD------------GNEVIKGGVLSAMQHA------ SHEWM_1_PE1289 SHEWM_1_PE1289 AGDIKDTACTFWSL---CTS---KSD------------GKSVLEGGVIEALQRA-TPSTG SHEWM_1_PE1358 SHEWM_1_PE1358 DGNIKSTACSFWTPSAVCSA---GGD------------GNEVEKGGALSAMQAA------ SHONE1_1_PE3211 SHONE1_1_PE3211 NGNIKETACTIWTD---CTS---QKD------------GNKVEVGGAAAQLRGQ------ MATCH . : : * : * * ** : CONSENSUS ?GNI????C??W?????C???????D????????????GN?V??GG??????????????

AERS4_4_PE638 AERS4_4_PE638 -TNRNLYVVNSVASPKRLDVFNKAN---LVSIAGSADNLASYMQLA---------SSTEL COLP3_1_PE1177 COLP3_1_PE1177 -SDRKLYMENGDGAS-ALMTFNRTNLEA--AFTAASTSLAAALGVTDAD---ATIQSTAI FERBD_1_PE786 FERBD_1_PE786 -ATRQVLTDPATGDG-ALVALNRTS---LASAVGSEAELVSRIGAA---------GSNEL FERBD_1_PE792 FERBD_1_PE792 -AVRRILTDPASGNG-ALVPLTRAS---LSSALGSESELISRIGAA---------GAGEL SHEAM_1_PE1004 SHEAM_1_PE1004 ARDRNLLSDV---GG--LKPLTLSA---ARTKAGGDGALATLLGVE----------ESEV SHEAM_1_PE926 SHEAM_1_PE926 -DSRIIWSDIDSSEDMDKRKLTVQN---ASSYVGGDDALATYLGLPKLD------VDSEL SHEB2_1_PE3163 SHEB2_1_PE3163 -SVRKIVSDLGAGSS--LTPLTLAN---AQSAAGGDTALASYMRTS----------VDEL SHEB5_5_PE1048 SHEB5_5_PE1048 -SVRKIVSDLGAGSS--LTPLTLAN---AQSAAGGDTALASYMRTS----------VDEL SHEB8_2_PE1107 SHEB8_2_PE1107 -SVRKIVSDLGAGSS--LTPLTLAN---AQSAAGGDTALASYMRTS----------VDEL SHEB9_1_PE1157 SHEB9_1_PE1157 -SVRKIVSDLGVGSS--LTPLTLAN---AQSAAGGDTALASYMRTS----------VDEL SHEDO_1_PE2698 SHEDO_1_PE2698 -ANRKILSNLS--GG--LVSLTKSA---AATVAGGNANLATYIGVD----------ETSL SHEFN_1_PE2860 SHEFN_1_PE2860 LATRKVLTNTSDSGP--LVALTKSNAKIK--GNLTDVQLANFLNVD----------QNSI SHEHH_1_PE1131 SHEHH_1_PE1131 LKSRVLYTNNS--SS--LLSVEDVASSSMYTLLGKPTIDSVVVDSE----------TISV SHELP_1_PE1104 SHELP_1_PE1104 LKSRNIRTNVG--TS--IVGIQFSG-------------------FA----------SAYS SHELP_1_PE1176 SHELP_1_PE1176 -DSRTLYSNLG--GG--MDTLSLSA---AATKAGGQEDLANFMGVD----------KSQL SHEPA_1_PE1088 SHEPA_1_PE1088 -QKRKLLSNIGTNGA--MATFNKSN---ASSYAGGDAKLSLHMGVD----------ETQL SHEPC_1_PE1058 SHEPC_1_PE1058 LKNRTIYTNNG--SS--LINFSSSS-------------------FI----------SGHS SHEPW_1_PE3541 SHEPW_1_PE3541 -TSRTLYGNFGSNGG--LAAFSKSN---ASSVAGGDAALASYMGVT----------QSSL SHESA_2_PE1077 SHESA_2_PE1077 -SSRTLYSNLG--TG--LSPFTLSN---ASRKAGGDARLALYMGVD----------ETEL SHESA_2_PE3108 SHESA_2_PE3108 -ANRTILSNLGGASS--LSPLTLSN---AQNAAGGDQALATFMRTS----------IDEV SHESH_1_PE1199 SHESH_1_PE1199 LKNRKILTNSG--NS--LIDIDNLSTSTMYSLLGSPIAD-----SQ----------STAV SHESM_1_PE1085 SHESM_1_PE1085 -GSRTLYSNLG--TG--LSPFTLSN---ASRKAGGDARLALYMGVD----------ETEL SHESM_1_PE2939 SHESM_1_PE2939 LKDRKLKSLSG--SN--IVNITATS-------------------FV----------SDYS SHESR_2_PE1146 SHESR_2_PE1146 -SSRTLYSNLG--TG--LSPFTLSN---ASRKAGGDARLALYMGVD----------ETEL SHESR_2_PE3010 SHESR_2_PE3010 -NTRTMLSDLDSG----LVALTVAN---ASKFAGGSRELAALLGLNVTTTDSDAAVTAEL SHESW_1_PE3061 SHESW_1_PE3061 LKNRTIYTNNG--SS--LINFSSSS-------------------FI----------SGHS SHEVD_1_PE1009 SHEVD_1_PE1009 -GNRTLYGNFASGGG--LQAFTKNN---ASSLAGGDVALASYMKTD----------IDQL SHEVD_1_PE1172 SHEVD_1_PE1172 -RSRTLYSNLS--SE--MTILTKSE---AADFAGGRDSLASYMGVE----------ESQL SHEWM_1_PE1289 SHEWM_1_PE1289 ISARTIYSNLT--NP--MSDLA----------QVSESILSTSMGIV----------EADV SHEWM_1_PE1358 SHEWM_1_PE1358 -DSRTIYSNLN--TG--LTELTVNN---VTSTAGGTENLVNYLGVA----------EEQF SHONE1_1_PE3211 SHONE1_1_PE3211 -LNRTILSNLAGTSS--LSPLTLSN---AQNAAGGEQALATFMRTD----------IDEV MATCH * : . CONSENSUS ???R??????????????????????????????????L?????????????????????

AERS4_4_PE638 AERS4_4_PE638 DGQIDWTKGLDVDDEDYD-----------------GSTTIRPYIVGDPLHSRPLVVNYGC COLP3_1_PE1177 COLP3_1_PE1177 DEMLAWATGLDVDDEDED----------------TATDDMRKSVFGDPLHSKPLVVNYGG FERBD_1_PE786 FERBD_1_PE786 DGYVSWLQGLDPDDEDED----------------GASNDRRIDLIGDPLHSKPLAISFGG FERBD_1_PE792 FERBD_1_PE792 NGYVSWLQGLDPDDEDGD----------------GASNDRRVDLIGDPLHSKPLAINYGG SHEAM_1_PE1004 SHEAM_1_PE1004 ASLIDWARGVDVDDDNDN----------------GDRTEMRADVMGDPLHSKPLAINFGS SHEAM_1_PE926 SHEAM_1_PE926 KDTFDWIYGKNVDRDSEGALT------------SEDFAGVRGDIMGDPLHSQPLAIDYGG SHEB2_1_PE3163 SHEB2_1_PE3163 TNTFDWLKGIDVDDDNKD----------------GSTTDKRNDVMGDPLHSKPLALNFGS SHEB5_5_PE1048 SHEB5_5_PE1048 TNTFDWLKGIDVDDDNKD----------------GSTTDKRNDVMGDPLHSKPLALNFGS SHEB8_2_PE1107 SHEB8_2_PE1107 TNTFDWLKGIDVDDDNKD----------------GSTTDKRNDVMGDPLHSKPLALNFGS SHEB9_1_PE1157 SHEB9_1_PE1157 ANTFDWLKGIDVDDDNKD----------------GSTTDKRNDVMGDPLHSKPLALNFGS SHEDO_1_PE2698 SHEDO_1_PE2698 DAHFDWLKGADVDDDNAN----------------NNRTENRRDIMGDPLHSKPLALNFGS SHEFN_1_PE2860 SHEFN_1_PE2860 EDTLAWIKGQNVDNEKYG---------------LTTVPYLRQDILGDPLHSRPLVINYGT SHEHH_1_PE1131 SHEHH_1_PE1131 RQHLDWLYGVDVDDDDND----------------ENRTEARMDVMGDPLHSKPLAINFGA SHELP_1_PE1104 SHELP_1_PE1104 QEDLDWLYGVDVDDDDND----------------GNIYDAREDIMGDPLHSKPLAINFGE SHELP_1_PE1176 SHELP_1_PE1176 TNLFDWAKGLDVDNDKNQTTI------------ADPAKNWRNDIMGDALHSKPLALNFGS SHEPA_1_PE1088 SHEPA_1_PE1088 EDMFNWAKGYDVDDDNGN----------------SQTDDARDELMGDPLHSRPLAINFGT SHEPC_1_PE1058 SHEPC_1_PE1058 QADFDWLYGVDVDDENNN----------------NNTSDAREDVMGDPLHSKPLAINYGS SHEPW_1_PE3541 SHEPW_1_PE3541 NSYFDWAKGKDVDDDDND----------------SSKTDARQDIFGDPLHSKPLAMNFGT SHESA_2_PE1077 SHESA_2_PE1077 SEHFDWAKGIDVDNDKNQDLSA----------ASGATPNWRADIMGDALHSKPLALNFGS SHESA_2_PE3108 SHESA_2_PE3108 ANTLDWLKGIDVDDDNKN----------------GSTTDKRNDVMGDPLHSKPLALNFGS SHESH_1_PE1199 SHESH_1_PE1199 REHLDWLYGVDVDDDDNN----------------GSFSDTREDVMGDPLHSKPLAINFGP SHESM_1_PE1085 SHESM_1_PE1085 SEHFDWAKGIDVDNDKNQDLSA----------ASGATPNWRADIMGDALHSKPLALNFGS SHESM_1_PE2939 SHESM_1_PE2939 QADLDWLYGVDVDDDNNS----------------GSNTDAREDIMGDPLHSKPLAINFGK SHESR_2_PE1146 SHESR_2_PE1146 SEHFDWAKGIDVDNDKNQDLSA----------ASGATPNWRADIMGDALHSKPLALNFGS SHESR_2_PE3010 SHESR_2_PE3010 DKAFAWIYGKNVDVASTDANGNPIYTSIGVGLGGTRSGNIRADIMGDPLHSQPLAIDFGD SHESW_1_PE3061 SHESW_1_PE3061 QADFDWLYGVDVDDENNN----------------NNTSDAREDVMGDPLHSKPLAINYGS SHEVD_1_PE1009 SHEVD_1_PE1009 ANLFDWAKGVDVDDDNGN----------------NSVVDKREDIIGDPLHSKPLAINFGT SHEVD_1_PE1172 SHEVD_1_PE1172 ASLFSWTRGLDVDNDKNQKKI------------STPKSNWRTDIMGDALHSKPLALNFGD SHEWM_1_PE1289 SHEWM_1_PE1289 SDTVKWLYGYDVDGDNPG----------------GSATDYRSDIMGDPLHSKPLALNFGT SHEWM_1_PE1358 SHEWM_1_PE1358 PSLFGWAMGLDVDNNKGLESI------------PNPATNWRDDIMGDALHSKPLALNFGT SHONE1_1_PE3211 SHONE1_1_PE3211 ANTLDWLKGIDVDDDNKN----------------GSITDKRNDVMGDPLHSKPLALNFGS MATCH . * * : * . * :.**.***:**.:.:* CONSENSUS ?????W??G?DVD???????????????????????????R?D??GDPLHSKPLA?N?G?

AERS4_4_PE638 AERS4_4_PE638 AIPSGQS---TCTPDLRILMGTNAGFLHMFKDLG--------STVDESWAMIPYELLPKQ COLP3_1_PE1177 COLP3_1_PE1177 RVYDEDTNTYSGEDDIRIVIGTNSGALHMFKDND--------TSVAESWAFMPTEFINNI FERBD_1_PE786 FERBD_1_PE786 T------------KGVRILMGTNQGYIHMFRDDD--------TRISESWAYYLPDMLGTL FERBD_1_PE792 FERBD_1_PE792 T------------KGVRILMGTNQGFVHMFKDED--------TAISESWAYYLPDMLGTL SHEAM_1_PE1004 SHEAM_1_PE1004 E----------GSPDIRVIVGTNHGVLHMFKDEG--------TSVSESWAYLPWEMLPKQ SHEAM_1_PE926 SHEAM_1_PE926 D-----------GSNVRIFVGTNHGALHAFRDSG--------SSVSESWAFMPFQLLPNL SHEB2_1_PE3163 SHEB2_1_PE3163 S----------TATDIRIMLGTNQGVLHMFKDAG--------ESVSETWGFIPYELLPNL SHEB5_5_PE1048 SHEB5_5_PE1048 S----------TATDIRIMLGTNQGVLHMFKDAG--------ESVSETWGFIPYELLPNL SHEB8_2_PE1107 SHEB8_2_PE1107 S----------TATDIRIMLGTNQGVLHMFKDAG--------ESVSETWGFIPYELLPNL SHEB9_1_PE1157 SHEB9_1_PE1157 S----------TATDIRIMLGTNQGVLHMFKDEG--------DSVSETWGFIPYELLPNL SHEDO_1_PE2698 SHEDO_1_PE2698 E----------STPDIRVILGTNHGFLHMFKDAG--------TTVTESWAFMPYELLPNI SHEFN_1_PE2860 SHEFN_1_PE2860 T----------TSPDIRIIMGTNHGFVHMFKDIESEVNGESVSAVSESWAFIPHELLPNI SHEHH_1_PE1131 SHEHH_1_PE1131 S---------STSLDVRILVGTNQGLVHMFKDSDSGSKDYSVGTVEESWAFIPAELLSNV SHELP_1_PE1104 SHELP_1_PE1104 K-PNADG---TENLDVRVIVGTNQGLVHMFKDSDSGSNDYSVGSVTETWAFIPQELWHNV SHELP_1_PE1176 SHELP_1_PE1176 K----------SSPDIRILVGTNHGFMHMFKDDTT------ANEVSESWAFMPYELLPNI SHEPA_1_PE1088 SHEPA_1_PE1088 A----------NIPDIRIIMGTNHGFLHMFKDEN--------ETVSESWAFMPYELLPNI SHEPC_1_PE1058 SHEPC_1_PE1058 T----------TNLDVRILVGTNQGLVHMFKDSDTGNNDYSVGSVEESWAFIPNELWGNI SHEPW_1_PE3541 SHEPW_1_PE3541 A----------GSPDIRVIVGTNHGYLHMFKDED--------TSVSESWAFMPYELLPNI SHESA_2_PE1077 SHESA_2_PE1077 E----------DQPDIRIIVGTNHGFLHMFKDEG--------DSVSETWGFIPYELLPNF SHESA_2_PE3108 SHESA_2_PE3108 K----------TATDIRIILGTNQGVLHMFKDGG--------EAVSETWGFIPYELLPNL SHESH_1_PE1199 SHESH_1_PE1199 S---------TSSLDVRILVGTNQGLVHMFKDSDKGSADYSVGVVTESWAFAPAELLSNI SHESM_1_PE1085 SHESM_1_PE1085 E----------DQPDIRIIVGTNHGFLHMFKDEG--------DSVSETWGFIPYELLPNF SHESM_1_PE2939 SHESM_1_PE2939 K---------GADLDVRVLVGTNQGLVHMFKDSDTGSNDFNIGSVKESWAFIPPELWGNV SHESR_2_PE1146 SHESR_2_PE1146 E----------DQPDIRIIVGTNHGVLHMFKDEG--------DSVSETWGFIPYELLPNF SHESR_2_PE3010 SHESR_2_PE3010 --------------HTMIYVGTNHGVMHAFNDSG--------DSVAESWAFMPNQLFSNL SHESW_1_PE3061 SHESW_1_PE3061 T----------TNLDVRILVGTNQGLVHMFKDSDTGNNDYSVGSVEESWAFIPNELWGNI SHEVD_1_PE1009 SHEVD_1_PE1009 S----------SVPDIRVIMGTNHGFLHMFKDTG--------ASVTESWAFMPYELLPNI SHEVD_1_PE1172 SHEVD_1_PE1172 K----------ANPDIRVMVGTNHGFFHMFKDAG--------AEVSESWAFIPYELLPNL SHEWM_1_PE1289 SHEWM_1_PE1289 K----------TSPDIRIVLGTNQGLVHMFKDTG--------DEVEESWAFIPTELLSNV SHEWM_1_PE1358 SHEWM_1_PE1358 K----------STPDVRIVMGTNHGFLHMFKDDSS------SNSVTENWAFIPYELLPNL SHONE1_1_PE3211 SHONE1_1_PE3211 E----------TATDIRIILGTNQGVLHMFKDAG--------ESVSETWGFIPYELLPNL MATCH : :*** * .* *.* : *.*. :: . CONSENSUS ??????????????D?R???GTN?G??HMFKD????????????V?E?W?F?P?ELL?N?

AERS4_4_PE638 AERS4_4_PE638 EALRLNAESADH-LYGVDASPVALIKDANSNGVLKASEGDFVWLFFGLRAGGSSYYALDI COLP3_1_PE1177 COLP3_1_PE1177 KPLRTSPAS-ANKIYGIDGEISIYQDDKNGDGIIGA--GDTAWIFFGLRRGGSSYYALDI FERBD_1_PE786 FERBD_1_PE786 DELRTNAQTGGHTVYGVDGAPSAYVHDVDGDGNIEAP-TDSVYVYFGLRRGGRAYYALDV FERBD_1_PE792 FERBD_1_PE792 NELRTNPQTGGHTVYGVDGVAAAYINDVNGDGIIEAS-TDSVSLYFGLRRGGRAYYALDL SHEAM_1_PE1004 SHEAM_1_PE1004 ATLRENLPSGRHSVYGIDGSPVAWVKNGA-SG------IQKAWLFFGLRRGGDAYYALDI SHEAM_1_PE926 SHEAM_1_PE926 ATIRRDSYLAGHSVYGIDGSPVAHIERNA-SGL-----IMKAWLFVGLRRGGQSYYAINI SHEB2_1_PE3163 SHEB2_1_PE3163 TELRSNDPSGVHTVYGIDSSPVAYTETDA-TGK-----VIKAWVYVGMRRGGSSYYALNV SHEB5_5_PE1048 SHEB5_5_PE1048 TELRSNDPSGVHTVYGIDSSPVAYTETDA-TGK-----VIKAWVYVGMRRGGSSYYALNV SHEB8_2_PE1107 SHEB8_2_PE1107 TELRSNDPSGVHTVYGMDSSPVAYTETDA-TGK-----VIKAWVYVGMRRGGSSYYALNV SHEB9_1_PE1157 SHEB9_1_PE1157 TELRSNDPSGVHTVYGMDSSPVAYTEMDD-TGK-----VIKAWVYVGMRRGGSSYYALNV SHEDO_1_PE2698 SHEDO_1_PE2698 RPLKANVPSGVHSVYGMDSSPVAYVKRSA-SGS-----IEKAWLFVGMRRGGKSYYAIDI SHEFN_1_PE2860 SHEFN_1_PE2860 KSLRDNPQTGVHSVYGMDGSPVPYLEYDA-DGK-----VNKAWIFMGMRRGGTSYYALDV SHEHH_1_PE1131 SHEHH_1_PE1131 SALKSNLPTGKHSVYGMDLSPVAYTETDS-TGK-----VNKAWVYLGMRRGGMSYYALDI SHELP_1_PE1104 SHELP_1_PE1104 PTLRKNYSTGSHSVYGMDLSPVAYTETDS-SGK-----VNKAWVFLGMRRGGTSYYALDI SHELP_1_PE1176 SHELP_1_PE1176 QTLRNNVPTGVHSVYGIDGSPVAYVKNGA-SG------VEKAWLFFGMRRGGDSYYALDI SHEPA_1_PE1088 SHEPA_1_PE1088 RELKANVPTGVHSVYGLDSSPVSYVKTGA-SG------LDKAWVFVGMRRGGKSYYAFDV SHEPC_1_PE1058 SHEPC_1_PE1058 PLLRQNPATGVHSIYGMDLSPVAYTESDA-TGK-----LTKAWVYLGMRSGGASYYALDI SHEPW_1_PE3541 SHEPW_1_PE3541 RELKANVPTGVHSIYGLDSPPVSYVKAAA-DGS-----VEKAWLFVGMRRGGKSYYALDI SHESA_2_PE1077 SHESA_2_PE1077 RDLKANAPTGVHSVYGIDGSPVAYTKMQG-KR------IEKAWVFVGMRRGGNAYYALDI SHESA_2_PE3108 SHESA_2_PE3108 FELRTNDPSGVHTVYGMDSSPVAYTETDS-TGK-----VNKAWVFAGMRRGGSSYYALNV SHESH_1_PE1199 SHESH_1_PE1199 PELRENLPTGEHSVYGMDLSPVAYTETDS-SGK-----VNKAWVYLGMRRGGVSYYALNI SHESM_1_PE1085 SHESM_1_PE1085 RDLKANAPTGVHSVYGIDGSPVAYTKMQG-KR------IEKAWVFVGMRRGGNAYYALDI SHESM_1_PE2939 SHESM_1_PE2939 PKLRQNPPIGEHSVYGMDLSPVAYTETNE-NGE-----VNKAWVFLGMRRGGSSYYALDI SHESR_2_PE1146 SHESR_2_PE1146 RDLKANAPTGVHSVYGIDGSPVAYTKMQG-KR------IEKAWVFVGMRRGGNAYYALDI SHESR_2_PE3010 SHESR_2_PE3010 STIRRNDYSFGHSEYGLDGSPVSYIERDD-SA------IKTAWLYFGMRRGGQSYFAMDV SHESW_1_PE3061 SHESW_1_PE3061 PLLRQNPATGVHSIYGMDLSPVAYTESDT-TGK-----LTKAWVYLGMRSGGASYYALDI SHEVD_1_PE1009 SHEVD_1_PE1009 TVLRANVPTGVHSIYGMDSPPVSYVKTGP-SG------IEKAWIFAGMRRGGKSYYALDI SHEVD_1_PE1172 SHEVD_1_PE1172 KILRANVPTGVHSVYGIDASPVAYTKMDD-SG------IETAWVFFGMRRGGGSYYAIDI SHEWM_1_PE1289 SHEWM_1_PE1289 PVLKQNVANGGHYIYGMDGSPVSYTETDS-SGR-----VNKAWVFMGMRRGGSSYYALDV SHEWM_1_PE1358 SHEWM_1_PE1358 KTLRANVPTGVHSVYGVDGSPVAYTESND-SG------IEKAWLFFGMRRGGSSYYAIDI SHONE1_1_PE3211 SHONE1_1_PE3211 IELRTNDPSGVHTVYGMDSSPVAYTETDS-TGK-----VNKAWVFVGMQRGGSSYYALDV MATCH :: . : **:* . . :: *:: ** :*:*::: CONSENSUS ??L??N???G?H??YG?D?SPV?Y???????G????????KAW???GMRRGG?SYYAL??

AERS4_4_PE638 AERS4_4_PE638 TNPD-APSLKWVINSQTTGFSLLGETWSVPEVAYVPWDA----SPSNKRLVMVFSGGYDA COLP3_1_PE1177 COLP3_1_PE1177 SSPD-APKLLWRIDSSKPNFTQLGQSWSQPKIGYSALNFTT-GTGSTAKPVLFIGGGYDT FERBD_1_PE786 FERBD_1_PE786 SDPD-NPRRLWKLSNQSPGMSELGQSWSEPVVTTIPAND--------GNPVVIFGGGYDL FERBD_1_PE792 FERBD_1_PE792 SDPD-NPSRLWKLSNESTGMDELGQSWSEPIITRIPGNN--------NKPVVIFGGGYDL SHEAM_1_PE1004 SHEAM_1_PE1004 TNPD-APRFMWRIDGNSPGMDLLGQSWSKPVVTFIPGRE------S--SPVLILGGGYSP SHEAM_1_PE926 SHEAM_1_PE926 TEPD-SPKLMWHISNSTSEFSNMGQTWSTPVVTKIPGS---------EKPVVIFGGGYNQ SHEB2_1_PE3163 SHEB2_1_PE3163 TNPD-SPTLMWSINPSTEGFSDLGQTWSEPIVTKIVGYE---------KPVLIFGGGYDT SHEB5_5_PE1048 SHEB5_5_PE1048 TNPD-SPTLMWSINPSTEGFSDLGQTWSEPIVTKIVGYE---------KPVLIFGGGYDT SHEB8_2_PE1107 SHEB8_2_PE1107 TNPD-SPTLMWSINPSTEGFSDLGQTWSEPIVTKIVGYE---------KPVLIFGGGYDT SHEB9_1_PE1157 SHEB9_1_PE1157 TNPD-SPTLMWSINPSTEGFSDLGQTWSEPIVTKIVGYE---------KPVLIFGGGYDT SHEDO_1_PE2698 SHEDO_1_PE2698 TNPD-NPSFMWKVDANSAGMSELGQTWAKPVIAFIPGWPTGNADAGSAKPVLIVGAGYSP SHEFN_1_PE2860 SHEFN_1_PE2860 TNKDAAPTLLWVKNN--SNYPLLGQSWSEPVITKISGWK---DSTGKAKPVLVIGAGYNP SHEHH_1_PE1131 SHEHH_1_PE1131 TNPD-QPKFKWKIDSNATGLEELGQTWSEPVVTFIPGIE---------SPVLIFGGGMA- SHELP_1_PE1104 SHELP_1_PE1104 TNPD-APSFKWKIDSNSTGFEELGQSWSEPVVTFVPGID---------DPVLVIGGGMA- SHELP_1_PE1176 SHELP_1_PE1176 SNPD-SPSFKWRIDASSPGLSELGQSWSTPVVTTIRSAS------GTEKPVLIFGAGYSP SHEPA_1_PE1088 SHEPA_1_PE1088 TTPD-SPRFMWKIDPDSAGMSELAQTWSEPVVTHIPGWPAGNTDPSKAKPVLIFGAGYSP SHEPC_1_PE1058 SHEPC_1_PE1058 TAVD-APTFKWMINSDSTSFEDLGQTWSEPVVTYIPGVK---------DPILIFGGGMA- SHEPW_1_PE3541 SHEPW_1_PE3541 SNPD-KPTFMWKINSNSTGMSELGQTWAEPVVTYIPGWPTGNTEFSKAKPVLIFGAGYSP SHESA_2_PE1077 SHESA_2_PE1077 TSPD-NPTFMWRIDASSPGMGELGQSWSTPVVTTIPSAT------G-DKPVLIFGAGYTP SHESA_2_PE3108 SHESA_2_PE3108 TNPD-NPSLMWTINPSTDGFADLGQTWSEPIVTKIVGYE---------KPVLIFGGGYDV SHESH_1_PE1199 SHESH_1_PE1199 TNPD-SPAFKWKIDSNTSGLEELGQTWSEPVVTSISGVE---------GPVLIFGGGMA- SHESM_1_PE1085 SHESM_1_PE1085 TSPD-NPTFMWRIDASSPGMGELGQSWSTPVVTTIPSAT------G-DKPVLIFGAGYTP SHESM_1_PE2939 SHESM_1_PE2939 TTPD-SPIFKWKIDSSTSGLAKLGQSWSEPLVTFIPGHE---------TPVLIFGGGLA- SHESR_2_PE1146 SHESR_2_PE1146 TSPD-NPTFMWRIDASSPGMGELGQSWSTPVVTTIPSAT------G-DKPVLIFGAGYTP SHESR_2_PE3010 SHESR_2_PE3010 KG-A-TPTLKWTISNTTAGFSNLGQTWSTPVVTKVPIND--------GKPVLIFGGGYNP SHESW_1_PE3061 SHESW_1_PE3061 TAAD-APTFKWMINSDSTSFEDLGQTWSEPVVTYIPGVK---------DPILIFGGGMA- SHEVD_1_PE1009 SHEVD_1_PE1009 TNPD-SPSFMWKIDSDSEGMSELGQTWSEPVVTLIPGWPVGNTDPDLASPVLIFGAGYSP SHEVD_1_PE1172 SHEVD_1_PE1172 SDPD-SPEFMWKIDSNSEGMSELGQSWSTPVVTTIQGES------G-EQPVLIFGAGYSP SHEWM_1_PE1289 SHEWM_1_PE1289 TSPD-SPSVKWIITPDSSGFAELGQSWSEPIVTTIPGHS---------GPVLIFGGGYDA SHEWM_1_PE1358 SHEWM_1_PE1358 SNPD-NPSFMWKVDASSPGMSELGQSWSTPVVTTIPGRS------S-ESPVLIFGAGYSP SHONE1_1_PE3211 SHONE1_1_PE3211 SNPD-SPSLMWTINPSSDGFVDLGQTWSEPIVTKIVGYD---------KPVLIFGGGYDE MATCH . * * :.::*: * : ::....* CONSENSUS ??PD??P???W?I?????G???LGQ?WS?P?VT?I??????????????PVLIFG?GY??

AERS4_4_PE638 AERS4_4_PE638 NK-SKVGI-GSSDSKGMGLYMVDADSGALVFSATPGTG-SSTNKQVTGMVDSMPGPVSTL COLP3_1_PE1177 COLP3_1_PE1177 KKDS-TGV-ATPDDKGQGIYMLDAATGGLLWSGLPTGG----TTAFPG-EHSIPSPIALL FERBD_1_PE786 FERBD_1_PE786 N-KDSNGV-GSADSMGRAIYIVDAATGDLVHRFEAGATAAEGVTPLP-AEDGIAAKISAL FERBD_1_PE792 FERBD_1_PE792 N-KDGRAV-GSADSMGRAIYIVDAATGALVHRFEAGAALAEGVTPLP-AEDSIAAKISVL SHEAM_1_PE1004 SHEAM_1_PE1004 SNKDIPGV-GTPDNLGTAVFIVDAATGALVHAFGPNNAGN--MTVMPGIKDSIPNEVAVL SHEAM_1_PE926 SHEAM_1_PE926 GYDSGD----GSNSVGRMVYLVDAESGSLLYSFGAN--GN---TVLTGIEDSIVGSIATL SHEB2_1_PE3163 SHEB2_1_PE3163 SFDATP----SSSPAGRAVYIVDAEKGTLIHSFGGSTSG---ATVLSGIQDSIPNSVAVL SHEB5_5_PE1048 SHEB5_5_PE1048 SFDATP----SSSPAGRAVYIVDAEKGTLIHSFGGSTSG---ATVLSGIQDSIPNSVAVL SHEB8_2_PE1107 SHEB8_2_PE1107 SFDATPP---SSSPAGRAVYIVDAEKGTLIHSFGGSASG---ATVLSGIQDSIPNSVAVL SHEB9_1_PE1157 SHEB9_1_PE1157 SFDATP----SSAPAGRAVYIVDAEKGTLIHSFGGSASG---ATVLSDIQDSIPNSVAIL SHEDO_1_PE2698 SHEDO_1_PE2698 ATKDGAAV-GTDDSNGRGAFVLDAETGALVHAFGTSSGSN--ATKLPGITDSVPNSVALL SHEFN_1_PE2860 SHEFN_1_PE2860 NTKDGASV-GTNDTTGAGIYILDAATGSKLHSFSAS--GS--DTTMPGIVDSIPSKVAVL SHEHH_1_PE1131 SHEHH_1_PE1131 ----------SPDGTGEAVYIVNADTGAYIDKFTDSSMS------------SIPNKVAVL SHELP_1_PE1104 SHELP_1_PE1104 ----------SSEGTGEAVYIVNAKSGAFIKKFSATGMA------------SVPNKVAVL SHELP_1_PE1176 SHELP_1_PE1176 AGKDGKDL-GTKDNKGRGVFIVDADTGKLIHQFGA--GG---GTALPGIQDSIPSGVAVL SHEPA_1_PE1088 SHEPA_1_PE1088 STKDGANV-GIQDTEGRGVYIVDAETGTLVHTFGPDSSSS--ATQIPGITDSIPNSVAVL SHEPC_1_PE1058 SHEPC_1_PE1058 ----------SSDGSGAAVYIVNADTGAFITKFTADDMG------------SVVTKVAVL SHEPW_1_PE3541 SHEPW_1_PE3541 ATKDSAAV-GSPDTLGRGVFIVDAETGKLIHSFAANGGAS--VTQLPGITDSIPNSVAVL SHESA_2_PE1077 SHESA_2_PE1077 ATKDGAEI-GSDDSQGRGVFIVDAETGALIHQFGG-NGA---NTLLPGIANSIPSSVAVL SHESA_2_PE3108 SHESA_2_PE3108 SFDATP----SSSPSGRAVYIVDAEKGILIHSFGGSASG---ATVLPDIQGSIPNSVAVL SHESH_1_PE1199 SHESH_1_PE1199 ----------SSDGAGEAVYIVNADTGEFIHKFTAAGMY------------SVPNKVAVL SHESM_1_PE1085 SHESM_1_PE1085 ATKDGAEI-GSDDSQGRGVFIVDAETGALIHQFGG-SGA---NTQLPGIANSIPSSVAVL SHESM_1_PE2939 SHESM_1_PE2939 ----------SATGSGEAIYIVDANKGTFIHSFTADGMN------------SVPNKVAVL SHESR_2_PE1146 SHESR_2_PE1146 ATKDGAEI-GSDDSRGRGVFIIDAETGALIHQFGG-SGA---NTQLPGIANSIPSSVAVL SHESR_2_PE3010 SHESR_2_PE3010 GYDAAG----GKNSFGRDVYIVDADTGTLLHTFGIG--GT--DTPLPNITDSIVGSIATL SHESW_1_PE3061 SHESW_1_PE3061 ----------SSDGSGAAVYIVNADTGAFITKFTADDMG------------SVVTKVAVL SHEVD_1_PE1009 SHEVD_1_PE1009 STKDAAAV-GIDDTEARGVFIVDAKTGVLVHSFGPASGSS--VTQMPGITDSIPNSVAVL SHEVD_1_PE1172 SHEVD_1_PE1172 AGKDSASI-GSVDTKGRGVFIVNAQDGELIHHFGVGTSS---GTQIPGIIDSIPSSVAVL SHEWM_1_PE1289 SHEWM_1_PE1289 PLYDADTVPSTAASKGKAIYIVDADTGALVHAFTDTGVG---GTKMDGLVDSIPNSVAIL SHEWM_1_PE1358 SHEWM_1_PE1358 SGKDGAGI-GADDVKGRGVFILDAETGALVHQFGSASTG---GTQLPGISDSIPSSVAVL SHONE1_1_PE3211 SHONE1_1_PE3211 SFDATP----TTSPQGRAIYIVDAQKGTLIHSFGGSASG---ATVLPGIQGSIPNSVAVL MATCH . ::::* * : .: :: * CONSENSUS ???????????????G????IVDA??G?????F??????????????????S?P??VA?L

AERS4_4_PE638 AERS4_4_PE638 DSDGDGRTDRIYAGDTGGNIWRLDMPSTS----TSAWSVFKFASLGSDDVQANDRRFFTQ COLP3_1_PE1177 COLP3_1_PE1177 DSTGDGLIDRLYTGDTGGNVWRVDMPGKE----TSDFSISQLASLGGG---VNDQRFFYE FERBD_1_PE786 FERBD_1_PE786 DSDGDGLTDRLYAVDTGANIWRVDMPGTD----RDGWSVHQFAELGGD-TLADDRRFFGE FERBD_1_PE792 FERBD_1_PE792 DSDGDSVTDRLYAVDTGGNIWRVDMPGTD----SGDWSVHHFAELGGD-TQANDRRFFGE SHEAM_1_PE1004 SHEAM_1_PE1004 DANNDGLTDRIYATDTGGNVWRMDLPGATPKDANRRWSAFKFASLGGM-TTGSDRRFFAA SHEAM_1_PE926 SHEAM_1_PE926 DSNSDGYTDRLYAADLGGNVWRMDLPSAD----KSTWSGFKFAELGGNLP-STDRRFFYE SHEB2_1_PE3163 SHEB2_1_PE3163 DSNNDGYTDRIYATDVGGNVWRMDLPSAS----QSSWTAFKFAALGGS--NNDNRRFFAE SHEB5_5_PE1048 SHEB5_5_PE1048 DSNNDGYTDRIYATDVGGNVWRMDLPSAS----QSSWTAFKFAALGGS--NNDNRRFFAE SHEB8_2_PE1107 SHEB8_2_PE1107 DSNNDGYTDRIYATDVGGNVWRMDLPSAS----QSSWTAFKFAALGGS--NNDNRRFYAE SHEB9_1_PE1157 SHEB9_1_PE1157 DSNNDGYTDRIYATDVGGNVWRMDLPSAS----QSSWTAFKFAALGGS--NNDNRRFYAE SHEDO_1_PE2698 SHEDO_1_PE2698 DSNNDRLTDRIYLTDTGANVWRIDMPSANPSDSTRPWTAFKFASLGGS-SVATDRRFFAE SHEFN_1_PE2860 SHEFN_1_PE2860 DSNNDQLTDRIYATDTGANVWRLDLPGL-PTDTQNPWSAYHFASMGGG-DLTSDIRFYSE SHEHH_1_PE1131 SHEHH_1_PE1131 DSNNDGVTDRIYATDISGNVWRMDLPSKV----SSDWSVFQFASISAS-LSPNNRMFFAE SHELP_1_PE1104 SHELP_1_PE1104 DSNNDGITDRIYAADIGGNIWRMDMPEST----QSTWSTFKFASIATS-TSPNDRMFFAE SHELP_1_PE1176 SHELP_1_PE1176 DASGDGNTDRIYAVDTGGSVWRMDMPRAD----KASWSAFKFADLGGK-SLLQNRRFYSA SHEPA_1_PE1088 SHEPA_1_PE1088 DSNSDKLTDRIYASDTGGNVWRLDLPSANPKDSTNPWTAFKFADLGGS-SLTSDRRFFAE SHEPC_1_PE1058 SHEPC_1_PE1058 DSDNDGATDRIYASDITGNVWRIDLASTT----QSEWTIFKFASIA-G-ESPNNRMFFAE SHEPW_1_PE3541 SHEPW_1_PE3541 DSNGDKLTDRFYATDTGANVWRIDLPSANPKDSIKPWTAFKFADLGGA-STTSDRRFFAE SHESA_2_PE1077 SHESA_2_PE1077 DGNGDGRTDRIYATDTQGNVWRMDMPSAN----TSTWSGFKFAALGDRSSVAGDRRFFSG SHESA_2_PE3108 SHESA_2_PE3108 DSNNDGYTDRIYASDVTGNIWRMDLPSAS----IDTWTAFKFASLGGT--NSDNRRFFAE SHESH_1_PE1199 SHESH_1_PE1199 DSNNDGITDRVYATDIGGNVWRMDLPSAD----KTSWSIFKFAAIGSG-TAPDDRMFFAE SHESM_1_PE1085 SHESM_1_PE1085 DGNGDGRTDRIYATDTQGNVWRMDMPTAN----TSTWSGFKFAALGDRSSVASDRRFFSG SHESM_1_PE2939 SHESM_1_PE2939 DSNNDGYTDRIYATDIAGNVWRMDLPTDE----ESKWSIFKFASIS-G-IAPDNRMFFAE SHESR_2_PE1146 SHESR_2_PE1146 DGNGDGRTDRIYATDTQGNVWRMDMPTAN----TSTWSGFKFAALGDRSSVASDRRFFSG SHESR_2_PE3010 SHESR_2_PE3010 DSNGDGITDRLYASDLGGNVWRMDMPASD----KTKWSAFMFASAGGAYDTSDDRRFFYE SHESW_1_PE3061 SHESW_1_PE3061 DSDNDGATDRIYASDITGNVWRIDLASTT----QSEWTIFKFASIA-G-ESPNNRMFFAE SHEVD_1_PE1009 SHEVD_1_PE1009 DANGDRLTDRIYATDTGGNVWRMDLPSAKPKDATNPWTVFKFADLGGG-TLASDRRFFAE SHEVD_1_PE1172 SHEVD_1_PE1172 DANDDGKTDRIYATDTGGNVWRMDLATSD----KSTWSAFKFASLGGG-SLSSNRRFFSG SHEWM_1_PE1289 SHEWM_1_PE1289 DSNNDGDTDRIYATDVGGHVWRIDLAEST----RSTWSSYKFADLGGS-TAINDRRFFAE SHEWM_1_PE1358 SHEWM_1_PE1358 DSNADGATDRIYATDTGGNVWRMDMPSAD----TNKWSGFKFASLGGG-VQSSDRRFYSA SHONE1_1_PE3211 SHONE1_1_PE3211 DSNNDGYTDRIYASDVTGNIWRMDLPTAS----SGTWTAFKFASLGGS--NSDNRRFFAE MATCH *. * **.* * . :**:*:. :: :* . : *: CONSENSUS D???DG?TDR?YA?D??GNVWR?D?P??????????W??FKFA??G????????RRFF??

AERS4_4_PE638 AERS4_4_PE638 PVVVRTINKQVTKTVIS-----GEDYFSFKERPFDAVLIGSGDRNRPSSESTVQNAYFML COLP3_1_PE1177 COLP3_1_PE1177 PTIARALISEIVKTEVTDADGVTTEVFVHQEIPYDAILLGSGDRTTPLGKD-TTDTLYMI FERBD_1_PE786 FERBD_1_PE786 VSVAQTSFELVENLVMNEGEEDEATLTTSVEVPYDAVVVGSGNRAHPNASG-TQDYLFAL FERBD_1_PE792 FERBD_1_PE792 VSVAQTSFELVENLVVNEGKEGETTVTASSEVPYDAVLVGSGNRAHPNGTG-TQNYLFAL SHEAM_1_PE1004 SHEAM_1_PE1004 PVVAQTALNNTLEYTSR-EKGRTTTVTTVQTIPYDAVVVGSGIRPAPQDDQ-REDMFFTL SHEAM_1_PE926 SHEAM_1_PE926 PSVAQTYFTNTTEVTVTDESGTT-TTVAYQNVPYDAVTLGSGNRADPLSLN-AEDMFFVL SHEB2_1_PE3163 SHEB2_1_PE3163 PVVAQTMFTNIAEVKVT-TGTGTTTTKTYQNVPYDAVVIGSGARPHPSSTA-VNDMFFTL SHEB5_5_PE1048 SHEB5_5_PE1048 PVVAQTMFTNIAEVKVT-TGTGTTTTKTYQNVPYDAVVIGSGARPHPSSTA-VNDMFFTL SHEB8_2_PE1107 SHEB8_2_PE1107 PVVAQTMFTNLAEVKVT-SGTGTTTTKTYQNVPYDAVVIGSGARPHPSSTA-VNDMFFTL SHEB9_1_PE1157 SHEB9_1_PE1157 PVVAQTMFTNLAEVKVT-SGTGTTTTKTYQNVPYDAVVIGSGARPHPSSTT-VNDMFFTL SHEDO_1_PE2698 SHEDO_1_PE2698 ATVAKTVFTNIAQVTTTDAQGQSTTVISHQNIPYDAVVIGSGNRPHPSDKG-RTDMFFTL SHEFN_1_PE2860 SHEFN_1_PE2860 PVIAQTAFSNVAEHTYTDINNNSVTSKQYQSIPYDAVVVGSGHRANPLNKS-RNDKFFVF SHEHH_1_PE1131 SHEHH_1_PE1131 PAVAQTQFNNIHSQSG---------TLSYQNIPYDAVTVGTGNRTNPLNTS-TDDMFYVF SHELP_1_PE1104 SHELP_1_PE1104 PSVAQTQFNNIHDNSG---------ELTYQSVPYDAVTIGTGNRTHPLDIN-TNDMFYVF SHELP_1_PE1176 SHELP_1_PE1176 PVVAQTMINNVSVVDYT-VNGKTTRVTTSQNVPYDAVVVGSGHRAAPSDTS-REDMFFTL SHEPA_1_PE1088 SHEPA_1_PE1088 PVVAQTVFTNLAEVDVT-YDGTTTTVKTYQDIPYDAVAIGTGHRPHPSDKT-RQDKLFTL SHEPC_1_PE1058 SHEPC_1_PE1058 PVVAQTQFNNVHSESG---------VLSYQKIPYDAVTIGTGNRNHPLDMT-TNDMFYVF SHEPW_1_PE3541 SHEPW_1_PE3541 AAVAQTMFTNISEVDVT-VDGTTTTTKTYQNVPYDAVVVGSGHRPHPLDLL-RSDKFFTL SHESA_2_PE1077 SHESA_2_PE1077 PAVAQTMVTNTFELTQV-VNGKSTKTVTKQNIPYDAVVVGSGHRAKPSDAS-RSDMFFAL SHESA_2_PE3108 SHESA_2_PE3108 PVVAQTMFTNLSEVSVT-TGGETVTTKTSQNVPYDAVAVGSGMRPSPSSTS-VNDMFFML SHESH_1_PE1199 SHESH_1_PE1199 PTVAQTQINNIHSESG---------VLSYQNLPYDAVTVGTGNRTHPLDTV-TNDMFYVF SHESM_1_PE1085 SHESM_1_PE1085 PTVAQTIITNTFELTQV-VNGKSTKTVTTQNIPYDAVVVGSGHRAKPSDVS-RSDMFFAL SHESM_1_PE2939 SHESM_1_PE2939 PTVAQTQFNNIHSENG---------VESYQSIPYDAVAVGTGNRTNPLDIK-TNDMFYVF SHESR_2_PE1146 SHESR_2_PE1146 PTVAQTIITNTFELTQV-VNGKSTKTVTTQNIPYDAVVVGSGHRAKPSDVS-RSDMFFAL SHESR_2_PE3010 SHESR_2_PE3010 PTVAQTYFTDTTEVMVTDADGNTEKVISYQNVPYDAVTLGSGNRADPLGTS-VNDKFFVI SHESW_1_PE3061 SHESW_1_PE3061 PVVAQTQFNNVHSESG---------VLSYQKIPYDAVTIGTGNRNHPLDMT-TNDMFYVF SHEVD_1_PE1009 SHEVD_1_PE1009 PAVAQTVFTNLSEVDVT-VGGTTTKTKTYQNVAYDAVVVGTGHRPHPSDKS-RSDMFFML SHEVD_1_PE1172 SHEVD_1_PE1172 PVVAQTMFNNISEVEYN-VNGATKTTITYQNIPYDAVVVGSGHRAMPSDLS-RADMFFTL SHEWM_1_PE1289 SHEWM_1_PE1289 PAVAQTTFSNISEVEVTDGEGATTTTTSYQNVPYDAVVIGSGSRPHPTSVV-TSDKFFVL SHEWM_1_PE1358 SHEWM_1_PE1358 PAVAQTVITNIAEVTVE-NGGTTTKTKTKLNIPYDAVVVGSGHRAMPSDLS-RSDMFFTL SHONE1_1_PE3211 SHONE1_1_PE3211 PVVAQTMFTNLSEVSVT-TGTETVTTKTHQNVPYDAVAVGSGMRSSPSSTN-VNDMFFML MATCH :.:: .:**: :*:* * * : : : CONSENSUS P?VAQT???N???????????????????Q??PYDAV??G?G?R??P???????D?F???

AERS4_4_PE638 AERS4_4_PE638 RDYGVVAKNYNTG-----APAPITM-TDLYDVSVDPLAGVTATNDLLSLRAAITSKSGWK COLP3_1_PE1177 COLP3_1_PE1177 KDSNIITKTFPSRP-DEDAMDLIAK-TDLYNYTTNPFDAATDDTAKYDLQKLASEESGWY FERBD_1_PE786 FERBD_1_PE786 QDRNIQTQTFGTT--ENPAPAPITP-GNLYSVSGDPFGNASTDSERLNQQLALGQKLGWY FERBD_1_PE792 FERBD_1_PE792 QDRNIRTQTFGTE--SNPAPEPIRI-SNLYSVSGDPFGSADGEEALLAEQLALGQKLGWY SHEAM_1_PE1004 SHEAM_1_PE1004 QDRNIGIRSFDGSNKDRLPPSALTL-ADLYDVTSSPPTT-------KEEEVRFGTLRGWY SHEAM_1_PE926 SHEAM_1_PE926 QDRNVVSQQFGD--GATAIPSPITF-GNLYDVTSAAPST-------EAENITFGTKLGWY SHEB2_1_PE3163 SHEB2_1_PE3163 QDRNVVTKSFTGSD----IPSVITI-NDLYDVSSSAPVS-------ETDNISFGKKLGWF SHEB5_5_PE1048 SHEB5_5_PE1048 QDRNVVTKSFTGSD----IPSVITI-NDLYDVSSSAPVS-------ETDNISFGKKLGWF SHEB8_2_PE1107 SHEB8_2_PE1107 QDRNVVTKSFTGSD----IPSVITI-NDLYDVSSSAPVS-------ETDNISFGKKLGWF SHEB9_1_PE1157 SHEB9_1_PE1157 QDRNVVTKSFTGSD----IPSVITI-NDLYDVSSSAPVS-------ETDNISFGKKLGWF SHEDO_1_PE2698 SHEDO_1_PE2698 QDRNVSSKSFNGTT-GNEIPVVLTK-DDLYDVTSAPPVG-------EAQNLAFGAKRGWY SHEFN_1_PE2860 SHEFN_1_PE2860 QDRNIISKSYSSAA-GNTVPDTLTI-SDLYDVTTESPTE-------ETALITFGLKRGWY SHEHH_1_PE1131 SHEHH_1_PE1131 QDRNVVTKTFSGTN----VPSPLEL-TDLYDVTSSAPIT-------ESDNVAFGKKRGWY SHELP_1_PE1104 SHELP_1_PE1104 QDRNVVTKTFTSTD----APAALTI-SELYDVTTAAPSS-------QSDNVTFGTKRGWF SHELP_1_PE1176 SHELP_1_PE1176 QDRNVVTQTFGGTG-RPKAPAPLTL-SDLYETTKLKANQ-------APDKIAISKKRGWY SHEPA_1_PE1088 SHEPA_1_PE1088 QDRNVVTRSFNGTN-GNTVPEPITL-VDLYDITSKAAST-------ESEDITFGKKFGWY SHEPC_1_PE1058 SHEPC_1_PE1058 QDRNVVTQIFE--E----KPSVLTI-NDLYDVSSSSPVS-------ESDNVAFGKTRGWY SHEPW_1_PE3541 SHEPW_1_PE3541 QDRNVVSRPFNGDE-GNEIPAAITM-ANLYNVSSAAPES-------ELENIEFGTKRGWY SHESA_2_PE1077 SHESA_2_PE1077 QDRNIVTQSFQGKPNQKPVPSALTL-SDLYDVTTAAPND-------KASEIAFGQKRGWY SHESA_2_PE3108 SHESA_2_PE3108 QDRNVVTKSFTGSN----IPSAITI-NNLYDVSSSAPTS-------ETDNISFSTKLGWF SHESH_1_PE1199 SHESH_1_PE1199 QDRDVVTKTFSSDD----IPAPLTL-TDLYNVSTSAPSS-------ESDNIAFGTKRGWY SHESM_1_PE1085 SHESM_1_PE1085 QDRNIVTQSFQGKPNQKPVPSALTL-SDLYDVTTAAPSN-------QASEIAFGQKRGWY SHESM_1_PE2939 SHESM_1_PE2939 QDRNVVTKQYVGAD----VPAPLNI-TNLYNVTSAAPVS-------QDENIAFGEKRGWY SHESR_2_PE1146 SHESR_2_PE1146 QDRNIVTQSFQGKPNQKPVPSALTL-SDLYDVTTAAPSN-------QASEIAFGQKRGWY SHESR_2_PE3010 SHESR_2_PE3010 QDRNVATQTFGSATGQTAVPDPIIYPDNLYDVTQAAPST-------ESEKIAFSAKRGWY SHESW_1_PE3061 SHESW_1_PE3061 QDRNVVTQIFE--E----KPSVLTI-NDLYDVSSSSPVS-------ESDNVAFGKTRGWY SHEVD_1_PE1009 SHEVD_1_PE1009 QDRNVISRSFNGEP-GNEAPAPLTL-SNLYNITTAAPAS-------DDENIDFGLKRGWY SHEVD_1_PE1172 SHEVD_1_PE1172 QDRNVALTSFKSGNTKVKIPEPLTL-ANLYDVSAAEPKS-------KAEHLSFGKTRGWY SHEWM_1_PE1289 SHEWM_1_PE1289 QDRNVVTRSVIGEP----VPEVLDM-SKLYNVTSTPPVT-------EAENISFGTKRGWY SHEWM_1_PE1358 SHEWM_1_PE1358 QDRNVVSRSFKGGGSGVVIPTTLTL-SELYDVTSTPPSD-----SDEQEQINFGKKRGWY SHONE1_1_PE3211 SHONE1_1_PE3211 QDRNVVTKSFTGSN----VPATITI-NNLYDVTSSAPTS-------ETDNINFGTKFGWF MATCH :* .: : .**. : ** CONSENSUS QDRN?????F?????????P???T????LY?V????P???????????????FG?K?GW?

AERS4_4_PE638 AERS4_4_PE638 YWLAESGEKSMGAGVVLQGKLYFTSFLPQVQS-----FEECTIQSIGAMRQYMVDMHYGT COLP3_1_PE1177 COLP3_1_PE1177 IDLRATGEKSTASALVIKGVAYFTTYTPASSS----VLISCI-PPKGSGELYAVDLALGT FERBD_1_PE786 FERBD_1_PE786 YPLA-PSEKALSAPVVVAGVAYYATFLPGTVA----EANSCVAAG--EGFFYAFSLQEGI FERBD_1_PE792 FERBD_1_PE792 FPLA-PSEKALSAPLVVSGVAYYTTYVPGTVS----AANSCVAPG--EGFFYAFSLQDGI SHEAM_1_PE1004 SHEAM_1_PE1004 YNFTRKGEKSLSAGSIIRGRVFFTSYVPGSAGAP--GTNQCLIPG--KGYLYGFDLHKGT SHEAM_1_PE926 SHEAM_1_PE926 YNFAVTGEKSLSPSVIIKGKVYFTSFIPTQPA-A--GQNVCSVSS--VGRLYTLDLHKGS SHEB2_1_PE3163 SHEB2_1_PE3163 YDFSGLGEKSLTAALIVQGKVYFTSYSPPADS-V--AENVCVVSG--SGKLYVFDLHKGT SHEB5_5_PE1048 SHEB5_5_PE1048 YDFSGLGEKSLTAALIVQGKVYFTSYSPPADS-V--AENVCVVSG--SGKLYVFDLHKGT SHEB8_2_PE1107 SHEB8_2_PE1107 YDFSGLGEKSLTAALIVQGKVYFTSYSPPADS-V--AENVCVVSG--SGKLYVFDLHKGT SHEB9_1_PE1157 SHEB9_1_PE1157 YDFSGLGEKSLTAALIVQGKVYFTSYSPPADS-V--AENVCVVSG--SGKLYVFDLHKGT SHEDO_1_PE2698 SHEDO_1_PE2698 YAFGSLGEKSLSAAAIIRGRVFFTSYVPGDS--S--SSNQCLVAG--VGRLYGFDLHKGT SHEFN_1_PE2860 SHEFN_1_PE2860 YRFADAGEKSLSAATIVQGKVFFTSYVPQTGA----TENACLVPG--EGRLRGRDLHKGG SHEHH_1_PE1131 SHEHH_1_PE1131 YLLSATGEKSLSAALIFDGKVYFTSFIPPTNNEINLDAGICGFSG--QGRLYVFDLHRGT SHELP_1_PE1104 SHELP_1_PE1104 YDYSVAGEKTLSASLIFDGKVYFTSFIPPTRTDVDLDAGICGFAG--QGRLYVFDLHKGT SHELP_1_PE1176 SHELP_1_PE1176 FKLPGLGEKNLSPATIINGQVFFTTFVPG-TA-A--SNNQCLTSG--MGFLYPFNLHYGT SHEPA_1_PE1088 SHEPA_1_PE1088 YSLGAIGEKSLAGASIIQGRVYFTSYVPGDT--S--STNQCLIAG--MGRLYSFALHKGT SHEPC_1_PE1058 SHEPC_1_PE1058 YDFTANGEKSLSASLIFDGKVYFTSFVPPTNQAVDLDAGVCGFSG--QGRLYVFDLHKGT SHEPW_1_PE3541 SHEPW_1_PE3541 YQFSGKGEKSLSAATIIQGRVFFTSYVPGDN--S--DANQCLVSG--VGRLYGFDLHRGI SHESA_2_PE1077 SHESA_2_PE1077 YNFSRKGEKSLSSATIVQGEVYFTSFVPG-SD-A--SVNQCLSSG--KGYLYKKNLHKGT SHESA_2_PE3108 SHESA_2_PE3108 YDFSGVGEKSLTAALIIDGKVYFTSYSPPADS-V--ADNVCVVSG--SGKLYAFDLHKGT SHESH_1_PE1199 SHESH_1_PE1199 YNFAGSGEKSLSASLIFDGKVYFTSFLPPVNTEVDLDAGICGFSG--QGRLYVFDLHKGT SHESM_1_PE1085 SHESM_1_PE1085 YDFSRKGEKSLSSATIVQGEVYFTSFVPG-SD-A--SVNQCLSSG--KGYLYKKNLHKGT SHESM_1_PE2939 SHESM_1_PE2939 YDFPSTGEKSLSASLIFNGKVYFTSFVPPTKQDVDLDAGICGFSG--QGRLYVFDLHRGT SHESR_2_PE1146 SHESR_2_PE1146 YDFSRKGEKSLSSATIVQGEVYFTSFVPG-SD-A--SVNQCLSSG--KGYLYKKNLHKGT SHESR_2_PE3010 SHESR_2_PE3010 YSFPGLGEKSLSPSVIIKGKVYFTSFTPTGPA-P--DPESCSVAS--VGKLYTLDLHTGL SHESW_1_PE3061 SHESW_1_PE3061 YDFTANGEKSLSASLIFDGKVYFTSFVPPTNQAVDLDAGVCGFSG--QGRLYVFDLHKGT SHEVD_1_PE1009 SHEVD_1_PE1009 YGFGGVGEKSLAGASIIEGRVFFTSYVPGDT--S--SSNQCLIAG--VGRLYGFNLHKGT SHEVD_1_PE1172 SHEVD_1_PE1172 YDFSRRGEKNLSSATIINGRVFFTSYVPG-SL-V--NSDQCLISG--KGYLYNFDLHKGQ SHEWM_1_PE1289 SHEWM_1_PE1289 FDFTGSGEKSLTAALIIDGKVFFTSFLPSVNE-V--SDLICSSSG--QGRLYVFDLHRGT SHEWM_1_PE1358 SHEWM_1_PE1358 YSFSRTGEKNLSPATIVNGRVFFTSFVPPGDN-S--SSDQCISAG--AGFLYNFDLHRGT SHONE1_1_PE3211 SHONE1_1_PE3211 YDFSGLGEKSLTAALIVQGKVYFTSYSPPADS-V--ADNVCLVSG--AGKLYAFDLHKGT MATCH .** :. * ::::: * * : * CONSENSUS Y?????GEKSL????I??G?V?FTS??P????????????C???G???G?LY???LH?G?

AERS4_4_PE638 AERS4_4_PE638 SFKYVVDQDGNETPQRYVEVNNK-VAD--DLVIHA---------------GDDSKIRIIG COLP3_1_PE1177 COLP3_1_PE1177 RRNLTQ-TEVRDNDDRVIKINND-WLGPPTLIMLPETDNDDTTV--------DPITGDII FERBD_1_PE786 FERBD_1_PE786 SINN-------------FSVGAR-LPDTPQILVPPAPEPVP--------EDWDPQLYLVG FERBD_1_PE792 FERBD_1_PE792 SINK-------------FSTGEG-VPDTPQIVVPPDPDPDT--------EGWNPQLHLVG SHEAM_1_PE1004 SHEAM_1_PE1004 RSYN----------QTYLEMGES-VPDTPQLVVPSSE-----------------AMYLIG SHEAM_1_PE926 SHEAM_1_PE926 RYNE----------AYIIDVCDNCIPQPPKIITPPPCDT-GEECSPDEILNPPPPVLIIG SHEB2_1_PE3163 SHEB2_1_PE3163 RTFS----------QLYFELGER-VPDTPQIVIPAPETG------------KDPYIYIIG SHEB5_5_PE1048 SHEB5_5_PE1048 RTFS----------QLYFELGER-VPDTPQIVIPAPETG------------KDPYIYIIG SHEB8_2_PE1107 SHEB8_2_PE1107 RTFS----------QLYFELGER-VPDTPQIVIPAPETG------------KDPYIYIIG SHEB9_1_PE1157 SHEB9_1_PE1157 RTFS----------QLYFELGER-VPDTPQIVIPAPETG------------KDPYIYIIG SHEDO_1_PE2698 SHEDO_1_PE2698 RSYT----------QTYFEMGER-VPDTPQLVIPPGGK---------------KYMYLIG SHEFN_1_PE2860 SHEFN_1_PE2860 KVYS--------NSQDYFKMSEQ-VPDTPTLVIPKNGD-------------DSSYMYLIG SHEHH_1_PE1131 SHEHH_1_PE1131 RTNS----------QLYYEVGER-VPDTPQIVIPESEDG------------EESKAYIIG SHELP_1_PE1104 SHELP_1_PE1104 RSYS----------ETYYEIGER-VPDTPQIVIPKPEEG------------EDSTAYIIG SHELP_1_PE1176 SHELP_1_PE1176 SNYT----------SVALEAGNL-VLDTPQLVIPADNK--GGQG-----KDGDAYMYLIG SHEPA_1_PE1088 SHEPA_1_PE1088 RTYT----------QEYIELGER-VPDTPPPLIPEGD----------------IYFPIPD SHEPC_1_PE1058 SHEPC_1_PE1058 RTYN----------QVYYEVGER-VPDTPQIVIPKPEDG------------EEVKAYIIG SHEPW_1_PE3541 SHEPW_1_PE3541 RSYT----------HEYLEMGER-VPDTPQLVVPPNGE-------------DDSYMYLIG SHESA_2_PE1077 SHESA_2_PE1077 NGYR----------TDFLYAGEL-VLDTPQLVIPPAAQPDAPNA-----KAPTPDMFLIG SHESA_2_PE3108 SHESA_2_PE3108 RTFS----------QLYYELGER-VPDTPQIVIPAPETG------------KDPYIYIIG SHESH_1_PE1199 SHESH_1_PE1199 RTSS----------QLYYEIGER-VPDTPQIVIPEPEEG------------EESIAYIIG SHESM_1_PE1085 SHESM_1_PE1085 NGYR----------TDFLYAGEL-VLDTPQLVIPPAAQPDDPNA-----KAPTLDMFLIG SHESM_1_PE2939 SHESM_1_PE2939 RTSN----------TLYYEVGER-VPDTPQIVIPEPEKG------------KEPEAYVIG SHESR_2_PE1146 SHESR_2_PE1146 NGYR----------TDFLYAGEL-VLDTPQLVIPPAAQPDDPNA-----KAPTPDMFLIG SHESR_2_PE3010 SHESR_2_PE3010 RFSQ----------NYYIDICDNCIPQPPKIITPPIDPE-HP-------EVIPDPVLIIG SHESW_1_PE3061 SHESW_1_PE3061 RTYN----------QVYYEVGER-VPDTPQIVIPKPEDG------------EEVKAYIIG SHEVD_1_PE1009 SHEVD_1_PE1009 RSYT----------HEYLEMGER-VPDTPQLVIPPNGN-------------GESYMYLIG SHEVD_1_PE1172 SHEVD_1_PE1172 RDFE----------Y--RKINDS-VPDTPQMIIPPRDAD--VDG-----NHPPSNIYLIG SHEWM_1_PE1289 SHEWM_1_PE1289 RSYE----------NVYYELGER-VPDTPQIVVPAPETG------------EDPYIYIIG SHEWM_1_PE1358 SHEWM_1_PE1358 RTHT----------Y--IRTGEF-VPDTPQLIVPPRVVNEGE-------EANPPNMYLIG SHONE1_1_PE3211 SHONE1_1_PE3211 RSFS----------QLYYELGER-VPDTPQIVIPAPETG------------KDPYIYIIG MATCH : CONSENSUS ????????????????????G???VPDTPQ???P????????????????????????IG

AERS4_4_PE638 AERS4_4_PE638 GAPGEEVILKDEGEGVPERCTGEGEC-SEGADEAEMDMTPKKIYLYEDEPQ COLP3_1_PE1177 COLP3_1_PE1177 VG--------------------------DKVISVDFSLATVRTYLYSTEVQ FERBD_1_PE786 FERBD_1_PE786 VGAGEDR---------------------TGTVATNQTLTPQRVYYHYGAQ- FERBD_1_PE792 FERBD_1_PE792 VGAGDKG---------------------AGTVATNQTLTPQRVYYHYGAH- SHEAM_1_PE1004 SHEAM_1_PE1004 IGKAPELMVKTRCEDN---NEHCDGCPPGDEKCIGGGMNTRKIYYYAN--- SHEAM_1_PE926 SHEAM_1_PE926 KGKCDEN-----------------GENCSGTVDLESGLTTNKIYYHIDE-- SHEB2_1_PE3163 SHEB2_1_PE3163 VGKGEKN----------------KDGEYSGTINVASGLGVNKIYYHINE-- SHEB5_5_PE1048 SHEB5_5_PE1048 VGKGEKN----------------KDGEYSGTINVASGLGVNKIYYHINE-- SHEB8_2_PE1107 SHEB8_2_PE1107 VGKGEKN----------------KDGEYSGTINVASGLGVNKIYYHINE-- SHEB9_1_PE1157 SHEB9_1_PE1157 VGKGEKN----------------KDGEYSGTINVASGLGVNKIYYHINE-- SHEDO_1_PE2698 SHEDO_1_PE2698 IGDAGDDMV------KKDPDPED-DPEDCVENCVGDGLQTNKIYYHVSE-- SHEFN_1_PE2860 SHEFN_1_PE2860 IGDAANDMIKKDLLG-------DDGCAAGDNKCVGGGLGVNQIYYHMKEN- SHEHH_1_PE1131 SHEHH_1_PE1131 VGKGECE-----------------NGECKGTVELGSGLTTNRIYYHLDESN SHELP_1_PE1104 SHELP_1_PE1104 VGKGECE-----------------DGECKGTVSLGSGLSTNRIYYHLDEKN SHELP_1_PE1176 SHELP_1_PE1176 IGNAAEKMEK---------VKPDDDCPAGDNRCIGGRLRAHKIYYYSE--- SHEPA_1_PE1088 SHEPA_1_PE1088 -APRLPCVE------GDVNCPKPPDCQNGDDKCVGSALGINRIYYHAND-- SHEPC_1_PE1058 SHEPC_1_PE1058 VGKGECE-----------------NGECKGTIELGSGLGANKIYYHINE-- SHEPW_1_PE3541 SHEPW_1_PE3541 IGAAGDKMEHKECPEGSLNCPPPPPCEAGDSKCVGGGLGVNRIYYHVDD-- SHESA_2_PE1077 SHESA_2_PE1077 IGKAVPE------------E---ATCESGNPKCIGSGPKANKIYYYVDQ-- SHESA_2_PE3108 SHESA_2_PE3108 VGKGDKN----------------ENGEYSGTINVASGLGVNKIYYHIDE-- SHESH_1_PE1199 SHESH_1_PE1199 VGKGECV-----------------DGECKGTVKLGSGLTTNRIYYHLDEKQ SHESM_1_PE1085 SHESM_1_PE1085 IGKAVPE------------E---ATCESGNPKCIGSGPKANKIYYYVDQ-- SHESM_1_PE2939 SHESM_1_PE2939 VGKGECE-----------------NGACKGTIKLGSGLKTNKIYYHIDE-- SHESR_2_PE1146 SHESR_2_PE1146 IGKAVPE------------E---ATCESGNPKCIGSGPKANKIYYYVDQ-- SHESR_2_PE3010 SHESR_2_PE3010 AGTCDEK-----------------GENCTGTVNLDSGLETNKIYYHINE-- SHESW_1_PE3061 SHESW_1_PE3061 VGKGECE-----------------NGECKGTIELGSGLGANKIYYHINE-- SHEVD_1_PE1009 SHEVD_1_PE1009 IGAAGEDME------KAGGGGDGDGCPPGDERCVGGGLGVNRIYYHINE-- SHEVD_1_PE1172 SHEVD_1_PE1172 IGNAVPN------------EKTQAGCEPGDLNCVGGGLRASKIYYFQH--- SHEWM_1_PE1289 SHEWM_1_PE1289 VGKGEIK-----------------DGAPTGTINVGAGLGVNKIYYHIDE-- SHEWM_1_PE1358 SHEWM_1_PE1358 IGAALPG------------NP-PEGCDPSDLKCVGGGLSTNRIYYYTSD-- SHONE1_1_PE3211 SHONE1_1_PE3211 VGKGDIN----------------ENGEYSGTINVASGLGVNKIYYHIDE-- MATCH . : * . CONSENSUS ?G??????????????????????????????????GL????IYY??????


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