Alignment of the gene Family HOG000290717 of HOGENOM

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Isoforms are ON
AILMEGL192719_1_1_PE6 NOISO ACSIVQFCYFQDLQAARDFLFPHLREETPSG--AVRRDPSK-SNWEDDGWGA-WEETET- BOVINUN_004_2_2_PE6 NOISO ACSIVQFCSFQDLQAARDFLFPHLREETPSG--AVRRDPSKS-NWEDDGWGA-WEESEP- CALJA19_5_PE11 ENSCJAG00000011310 ACSIVQFCYFQDLQAVRDFLFPHLREEIPSG--AVRRDPSKSTDWEDDGWGA-WEETES- CANFA38_19_PE6 NOISO ACSIVQFCYFQDLQAARDFLFPHLREETPSG--AVRRDPSKSTNWEDDGWGA-WEETEP- CAVPO13_3_PE5 NOISO ----------------------------------------KSASWEDEGWGA-WDEAEL- CHICK3_PE373 NOISO SCALVPFGSFQDLEAARDFLCPHRRQGS----AAAGRESGKPTNWEDGGWGA-WDEAEL- DANRE17_27_PE32 ISOFORMIN SCCLLEFGRVQELRQVREFLFPKHNSTGPEG---DKAQAENELTWDDSDWGS-WDNPEGK DANRE17_27_PE33 ISOFORMIN SCCLLEFGRVQELRQVREFLFPKHNSTGPEG---DKAQAENELTWDDSDWGS-WDNPEGK DANRE17_27_PE34 ENSDARG00000044136 SCCLLEFGRVQELRQVREFLFPKHNSTGPEG---DKAQAENELTWDDSDWGS-WDNPEGK DASNOGS_2270_PE1 NOISO ------------------------------PSGAVRRDPXXXXXXXXXXX---XXXXXXX DIPORGS_4557_PE3 NOISO ACSIVQFCYFQDLQAARDFLFPQLRRXXXXX--XXXXXXXKSTNWEDDGWGA-WEETDL- ECHTEGS_570_PE2 NOISO ACSLVQFCYFQDLQASRDFLFPHLREETPSG--AARRDPSKSTNWEGDGLGA-WEETES- ERIEUGS_609_PE2 NOISO ACSIVQFCHFQDLQAARDFLFPHLREENPSG--AVRRDPSKSTGWEDDNWGA-WEETEV- FELCAGS_2186_PE3 NOISO ------------------------------------------------------------ FUGRU517_PE13 ENSTRUG00000005143 SCTLLEFCRLQELETVRDYLFQSQKIEPQEE---T-QKTDPELSWDVSDWESEWDSGDNK FUGRU517_PE14 ISOFORMIN SCTLLEFCRLQELETVRDYLFQSQKIEPQEE---T-QKTDPELSWDVSDWESEWDSGDNK FUGRU517_PE15 ISOFORMIN SCTLLEFCRLQELETVRDYLFQSQKIEPQEE---T-QKTASTVVT---DLGVNWMSTGP- FUGRU517_PE16 ISOFORMIN SCTLLEFCRLQELETVRDYLFQSQKIEPQEE---T-QKTGTN-SC---PFGFNWTQTGQ- GASACGROUPXV_17_PE10 ISOFORMIN SCSLLEFCRLQELHTVRDYLFLSQKSESVEE---KNQTAENELSWDSSDWEATWDGGENK GASACGROUPXV_17_PE11 ENSGACG00000013319 SCSLLEFCRLQELHTVRDYLFLSQKSESVEE---KNQTAENELSWDSSDWEATWDGGENK GORGO1_206_PE8 ENSGGOG00000013163 ACSIVQFCYFQDLQAARDFLFPHLREEILSG--ALRRDPSKSTDWEDDGWGA-WEENEP- GORGO1_206_PE9 ISOFORMIN ACSIVQFCYFQDLQAARDFLFPHLREEILSG--ALRRDPSKSTDWEDDGWGA-WEENEP- HS1_PE6877 ENSG00000118873 ACSIVQFCYFQDLQAARDFLFPHLREEILSG--ALRRDPSKSTDWEDDGWGA-WEENEP- LAMPAGS_245_2_PE5 NOISO ----------------------------------------KSTNWEDDGWGA-WEETDP- LOXAF74_9_PE6 ENSLAFG00000011101 ----------------------------------------------------------Q- LOXAF74_9_PE7 ISOFORMIN -----------------------------------------ASTWEDDSWMP-PEGWSP- MACEUGS_3247_PE1 NOISO ACSLLQFCHFQDLQAARDFLFPHLREETPSG--GARRDDGKSSNWEDDGWGA-WEEAET- MACMU1_155_PE12 ENSMMUG00000007784 ACSIVQFCYFQDLQAARDFLFPHLREEIPSG--ALRRDPSKSTDWEDDGWGA-WEETEP- MACMU1_155_PE14 ISOFORMIN ACSIVQFCYFQDLQAARDFLFPHLREEIPSG--ALRRDPSKSTDWEDDGWGA-WEETEP- MICMUGS_2029_PE4 NOISO ACSIVQFCYFQDLQAARDFLFPHLREEIPAG---VRRDPSKSTNWEDDGWGA-WEETEP- MONDO2_135_PE9 NOISO ACSLHQFCYFQDLQAARDFLFPHLREETPSGAGAARRDDGKSTNWEDDGWGA-WEETEI- MOUSE1_PE2676 NOISO ACSIVQFCSFQDLQSARDFLFPHLREETPG---ALKRDPSKTSSWEDDSWGA-WEETEP- MYOLUGS_5684_PE5 NOISO ----------------------------------------KSANWEDDGWGA-WEEAEPA NEMVE_3145_PE41 NOISO ------------------------------------------------------------ OCHPRGS_319_PE2 NOISO ACSIVQFCSFQDLQASRDFLFPHLREETPSG--AVRRDPSKSTNWEDDGWGA-WDETEA- ORNANULTRA67_7_PE11 ISOFORMIN -------L-QSLLHKLAPHPHPHLMGKN--LK-FLPSKLCKLTNWEDDGWGA-WDETEA- ORNANULTRA67_7_PE12 ENSOANG00000001428 ALPVLKYC-FSELQKIRSFIFPDVLYTNLPGV-CLAIFFCKLTNWEDDGWGA-WDETEA- ORYLA22_21_PE9 NOISO SCSLLEFGRLQELRTVRDFLFQGQKPDAAEE---RNQ-ADNELSWDTSDWESAWDTENNK OTOGAGS_376_PE2 NOISO ----------------------------------------KSANWEDDGWGA-WEETES- PANTR1_209_PE7 NOISO ACSIVQFCYFQDLQAARDFLFPHLREEILSG--ALRRDPSKSTDWEDDGWGA-WEENEP- PIG10_10_PE9 NOISO ACSIVQFCYFQDLQAARDFLFPHLREETPSG--ALKRDPSK-SNWEDDGWGT-WEETEP- POEGU3_10_PE6 NOISO SCSLVPFAHFQDLELARDFLSPHRRQGS----AAAGKESGKSTSWEDGGWGA-WDEAEL- PONPY1_32_PE1 NOISO ACSIVQFCYFQDLQAARDFLFPHLREEILSG--ALRRDPSKSTDWEDDGWGA-WEETEP- PTEVA294_PE5 NOISO ACSIVQFCHFQDLQAARDFLFPHLRADTPGC--AVRRDPSKSANWEDDGWGA-WEETEP- RABIT16_55_PE9 NOISO ------------------------------------------------------------ RAT13_PE910 ENSRNOG00000002353 ACSIVQFCSFQDLQSARDFLFPQLREETPG---ALRRDPSKTSNWEDDSWGA-WEETEP- RAT13_PE911 ISOFORMIN ACSIVQFCSFQDLQSARDFLFPQLREETPG---ALRRDPSKTSNWEDDSWGA-WEETEP- SORARGS_484_PE2 NOISO -----------------------------------------KSNWEDDGWGA-WEETEP- STRPU_68668_PE1 NOISO SCVLTNVGCFYDIAAVQRYLFPNWKKDEGG---------KDTDGWEDADWS--WSGEESN TARSYGS_3794_PE4 NOISO ACSIVQFCYFQDLQVARDFLFPHLREEIPSG--AVRRDPSKSTNWEDDGWGA-WEETEP- TUPGBGS_5421_PE5 NOISO ACSIVQFCYFQDLQAARDFLFPHLREETPSG--ALRRDPSK-SNWEDDGWGA-WEETEL- TURTRGS_3295_PE5 NOISO ACSIVQFCTFQDLQAARDFLFPRLREENPSC--TVRRDPSKS-NWEDDGWGA-WEETEP- XENTR182_1_PE3 ENSXETG00000002728 ACTLLEFCRFQDIKVVRDFLFPSLREEKKNS-------IDNFSNWEEEDWGS-WEENENN XENTR182_1_PE4 ISOFORMIN ACTLLEFCRFQDIKVVRDFLFPSLREEKKNSIAMDRQPVDNFSNWEEEDWGS-WEENENN XENTR182_1_PE5 ISOFORMIN ACTLLEFCRFQDIKVVRDFLFPSLREEKKNS-------IDNFSNWEEEDWGS-WEENENN MATCH CONSENSUS ????????????????????????????????????????????W????W???W??????

AILMEGL192719_1_1_PE6 NOISO -QEP--------------EEEGNTCKTQKTSWLQDCVLSLSPTNDLMVIARGQKAVFLVP BOVINUN_004_2_2_PE6 NOISO -QEP--------------EEEGNTCKPQKTCWLQDCILSLSPTNDLMVIAREQKAVFLVP CALJA19_5_PE11 ENSCJAG00000011310 -QEP--------------EEEGNTWKTQKTSWLQDCVLSLSPSNDLMVIAREQKAVFLVP CANFA38_19_PE6 NOISO -QEP--------------EEEGNSCKTQKTSWLQDCVLSLSPTNDLMVIARGQKAVFLVP CAVPO13_3_PE5 NOISO -PEL--------------EEEGSTCETQKTSWLQGCVLSLSPNSDLMVIAREQKAVFLVP CHICK3_PE373 NOISO -PEP--------------EEEESASKNQRNYWLQDCVLSLSPTNDLMVIANEQKAVFLVS DANRE17_27_PE32 ISOFORMIN EDGA---------------QAEEEEQHQSAPWLQDCVVSLSPCTDLLVIAREHKAAFLSA DANRE17_27_PE33 ISOFORMIN EDGA---------------QAEEEEQHQSAPWLQDCVVSLSPCTDLLVIAREHKAAFLSA DANRE17_27_PE34 ENSDARG00000044136 EDGA---------------QAEEEEQHQSAPWLQDCVVSLSPCTDLLVIAREHKAAFLSA DASNOGS_2270_PE1 NOISO XXXX--------------EEGGTSSKTQKMSWLQDCVLSLSPTSDLMVIAREQKAVFLVP DIPORGS_4557_PE3 NOISO -QEP--------------EEEGNTCRTQRTSWLQDCVLSLSPTNDLMVIAREQKAVFLVP ECHTEGS_570_PE2 NOISO -QGP--------------EEEGAVCKTQKASWLQHCVLSLSPTSDLMVIAREQKAVFLVX ERIEUGS_609_PE2 NOISO -QEP--------------EEEESTVKTQKTSWLQDCVLSLSPTSDLMVIAREQKAVFLVP FELCAGS_2186_PE3 NOISO ------------------EEEGNTCKAQKTSWLQDCVLSLSPTNDLMVIAREQKAVFLVP FUGRU517_PE13 ENSTRUG00000005143 QEDATSA-----------SMV-EETPGQSGPWLQHCVLTLSPCLDLLVVARGQKAAFLSA FUGRU517_PE14 ISOFORMIN QEDATSA-----------SMV-EETPGQSGPWLQHCVLTLSPCLDLLVVARGQKAAFLSA FUGRU517_PE15 ISOFORMIN -------------------QV-EETPGQSGPWLQHCVLTLSPCLDLLVVARGQKAAFLSA FUGRU517_PE16 ISOFORMIN ---IIKL-----------HQV-EETPGQSGPWLQHCVLTLSPCLDLLVVARGQKAAFLSA GASACGROUPXV_17_PE10 ISOFORMIN DDAA---------------TVEEVTAGQRAPWLQDCVVSLSPCSDLLVVAREQKAVFLSA GASACGROUPXV_17_PE11 ENSGACG00000013319 DDAATSA-----------TTVEEVTAGQRAPWLQDCVVSLSPCSDLLVVAREQKAVFLSA GORGO1_206_PE8 ENSGGOG00000013163 -QEP--------------EEEGNTCKTQKTSWLQDCVLSLSPTNDLMVIAREQKAVFLVP GORGO1_206_PE9 ISOFORMIN -QEP--------------EEEGNTCKTQKTSWLQDCVLSLSPTNDLMVIAREQKAVFLVP HS1_PE6877 ENSG00000118873 -QEP--------------EEEGNTCKTQKTSWLQDCVLSLSPTNDLMVIAREQKAVFLVP LAMPAGS_245_2_PE5 NOISO -QEP--------------EDEGSTCNTKKLPWFRDCVLSLSPTNDLMVIAREQKAVFLVP LOXAF74_9_PE6 ENSLAFG00000011101 -EPE--------------EEEGTTCKTQKTSWLQDCVLSLSPTNDLMVIAREQKAVFLVP LOXAF74_9_PE7 ISOFORMIN -ESQ--------------EEEGTTCKTQKTSWLQDCVLSLSPTNDLMVIAREQKAVFLVP MACEUGS_3247_PE1 NOISO -QEP--------------EEEETPYKTHKSYWLQDCILSLSPEXXXXXXXXXXXXXXXXX MACMU1_155_PE12 ENSMMUG00000007784 -QEP--------------EEEGNTCKTQKISWLQDCVLSLSPTNDLMVIAREQKAVFLVP MACMU1_155_PE14 ISOFORMIN -QEP--------------EEEGNTCKTQKISWLQDCVLSLSPTNDLMVIAREQKAVFLVP MICMUGS_2029_PE4 NOISO -QEP--------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MONDO2_135_PE9 NOISO -QEP--------------EEEETTCKSQKSYWLQDCVLSLSPTNDLMVIAREQKAVFLVP MOUSE1_PE2676 NOISO -REP--------------EEEGNTSKTQKNSWLQECVLSLSPTSDLMVIAREQKAAFLVP MYOLUGS_5684_PE5 NOISO LQEP--------------EEEGNTCKTQKTSWLQDCVLSLSPTNDLMLIAREQKAVFLVP NEMVE_3145_PE41 NOISO --------------------EPESKTNLNSSWLQDCCISLSPSNDTLVIAKNDKAVFLAS OCHPRGS_319_PE2 NOISO -QEP---------------EEGNACKAQKTFWLQDCVLSLSPTSDLMVIAREQKAVFLVS ORNANULTRA67_7_PE11 ISOFORMIN -KEP--------------EEE-IPCKTPKTYWLQDCVISLSPTNDLMVIAREQKAVFLVP ORNANULTRA67_7_PE12 ENSOANG00000001428 -KEP--------------EEE-IPCKTPKTYWLQDCVISLSPTNDLMVIAREQKAVFLVP ORYLA22_21_PE9 NOISO VQEGASS-----------T---QDCAAPSGPWLHDCIVSLSPCSDLLVVAREQKAVFLSA OTOGAGS_376_PE2 NOISO -QEP--------------EEEGKTYKTQKTSWLQDCVLSLSPTNDLMVIAREQKAVFLVX PANTR1_209_PE7 NOISO -QEP--------------EEEGNTCKTQKTSWLQDCVLSLSPTNDLMVIAREQKAVFLVP PIG10_10_PE9 NOISO -QEP--------------EEDGNSCKTQKTSWLQDCVLSLSPTNDLMVIARGQKAVFLVP POEGU3_10_PE6 NOISO -QEP--------------EEEESNSKNQRNYWLQDCVLSLSPTNDLMVIANEQKAVFLVP PONPY1_32_PE1 NOISO -QEP--------------EEEGNTCKTQKTSWLQDCVLSLSPTNDLMVIAREQKAVFLVP PTEVA294_PE5 NOISO -QEP--------------EEEGSTCKTQKTSWLQDCVLSLSPTNDLMVIAREQKAVFLVP RABIT16_55_PE9 NOISO --------------------------------------------------------FFSA RAT13_PE910 ENSRNOG00000002353 -QEP--------------EEEGNTSKTQKHSWLQECVLSLSPTSDLMVIAREQKAAFLVP RAT13_PE911 ISOFORMIN -QEP--------------EEEGNTSKTQKHSWLQECVLSLSPTSDLMVIAREQKAAFLVP SORARGS_484_PE2 NOISO -QEP--------------XXXXXXXXXXXXXXXXXXXXXXSPTSDLMVIAREQKAVFLVQ STRPU_68668_PE1 NOISO SVSLNVKTSLNAVAFQKEGSEVEAGPPDQDAWMQECSIALSPTSELMVIAFEQKAVFLQQ TARSYGS_3794_PE4 NOISO -QEP--------------E-EGNTSKTQKAFWLQDCVLSLSPTNDLMVIAREQKAVFLVP TUPGBGS_5421_PE5 NOISO -QEP--------------EEDGNTWKTHKSSWLQDCVLSLSPTNDLMVIAREQKAVFLVP TURTRGS_3295_PE5 NOISO -QDP--------------EEEGNTCKTQKTSWLQDCVLSLSPTNDLMVITREQKAVFLVP XENTR182_1_PE3 ENSXETG00000002728 KET---------------VEEETSSTSPPFHWLQDCVLSLSPTNDLMVIAHEQKAVFLAP XENTR182_1_PE4 ISOFORMIN KET---------------VEEETSSTSPPFHWLQDCVLSLSPTNDLMVIAHEQKAVFLAP XENTR182_1_PE5 ISOFORMIN KETA-------------QVEEETSSTSPPFHWLQDCVLSLSPTNDLMVIAHEQKAVFLAP MATCH CONSENSUS ???????????????????????????????WLQ?CV?SLSP??DL?VIAREQKA?FL??

AILMEGL192719_1_1_PE6 NOISO KWKYSDKGKEEMQFAVGWSGSLNVEE-------GERVTSALCIPLASQK--RSSTGRPDW BOVINUN_004_2_2_PE6 NOISO KWKHSDKGKEEMQFAVGWSGSLSVEE-------GECVTSALCIPLASQK--RSSTGRPDW CALJA19_5_PE11 ENSCJAG00000011310 KWKYSDKGKEEMQFAIGWSGSLNVEE-------GECVTSALCIPLASQK--RSSTGRPDW CANFA38_19_PE6 NOISO KWKYSDKGKEEMQFAVGWSGSLNVEE-------GECVTSALCIPLASQK--RSSTGRPDW CAVPO13_3_PE5 NOISO KWKQSDKGREEMQFAVAWSGPLSVEE-------GESVTSALCIPLASQK--RSSTGRPDW CHICK3_PE373 NOISO KWKQSDKGKEEMQYAVGWSGCLSVEE-------GECVSSVLCIPLASQKRNRSSTGRPDW DANRE17_27_PE32 ISOFORMIN KWRTAESGQEEMTLTVTWSGTLSIEE-------GESINSVICIPLASQK--RSSTGRPDW DANRE17_27_PE33 ISOFORMIN KWRTAESGQEEMTLTVTWSGTLSIEE-------GESINSVICIPLASQK--RSSTGRPDW DANRE17_27_PE34 ENSDARG00000044136 KWRTAESGQEEMTLTVTWSGTLSIEE-------GESINSVICIPLASQK--RSSTGRPDW DASNOGS_2270_PE1 NOISO KWKYSDKGKEEMQFAVGWSGSLNVEE-------XXXXXXXXXXXX--XXXXXSSTGRPDW DIPORGS_4557_PE3 NOISO KWKCSDKGKEEMQFAVGWSGSLNVEE-------XXXXXXXXXXXXXXXX--XXXXXXXXX ECHTEGS_570_PE2 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXX-------XEFVTSALCIPLASQK--RSSTGRPDW ERIEUGS_609_PE2 NOISO KWKHSDKGKEEMQFAVGWSGSLNVEE-------GERVTSALCIPLASQK--RSSTGRPDW FELCAGS_2186_PE3 NOISO KWKYSDKGKEEMQFAAGWSGSLNVEE-------GECVTSALCIPLASQK--RSSTGRPDW FUGRU517_PE13 ENSTRUG00000005143 KWCSAEGSREEMTMAVSWTGLLSVDD-------GEHVSSCMCIPLVSQK--RSSTGQPDW FUGRU517_PE14 ISOFORMIN KWCSAEGSREEMTMAVSWTGLLSVDD-------GEHVSSCMCIPLVSQK--RSSTGQPDW FUGRU517_PE15 ISOFORMIN KWCSAEGSREEMTMAVSWTGLLSVDD-------GEHVSSCMCIPLVSQK--RSSTGQPDW FUGRU517_PE16 ISOFORMIN KWCSAEGSREEMTMAVSWTGLLSVDD-------GEHVSSCMCIPLVSQK--RSSTGQPDW GASACGROUPXV_17_PE10 ISOFORMIN KWRTDDSGREEMTLAVSWTGTLSTDE-------GECVSSSICIPLASQK--RSSTGRPDW GASACGROUPXV_17_PE11 ENSGACG00000013319 KWRTDDSGREEMTLAVSWTGTLSTDE-------GECVSSSICIPLASQK--RSSTGRPDW GORGO1_206_PE8 ENSGGOG00000013163 KWKYSDKGKEEMQFAVGWSGSLNVEE-------GECVTSALCIPLASQK--RSSTGRPDW GORGO1_206_PE9 ISOFORMIN KWKYSDKGKEEMQFAVGWSGSLNVEE-------GECVTSALCIPLASQK--RSSTGRPDW HS1_PE6877 ENSG00000118873 KWKYSDKGKEEMQFAVGWSGSLNVEE-------GECVTSALCIPLASQK--RSSTGRPDW LAMPAGS_245_2_PE5 NOISO KWKHSDKGKEEMQFAVGWSGSLNVEE-------GECVTSALCIPLASQK--RSSTGRPDW LOXAF74_9_PE6 ENSLAFG00000011101 KWKHSDKGKEEMQFAVGWSGSLNVEE-------GECVTSALCIPLASQK--RSSTGRPDW LOXAF74_9_PE7 ISOFORMIN KWKHSDKGKEEMQFAVGWSGSLNVEE-------GECVTSALCIPLASQK--RSSTGRPDW MACEUGS_3247_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXX--XXXXXXXXX MACMU1_155_PE12 ENSMMUG00000007784 KWKYSDKGKEEMQFAVGWSGSLNVEE-------GECVTSALCIPLASQK--RSSTGRPDW MACMU1_155_PE14 ISOFORMIN KWKYSDKGKEEMQFAVGWSGSLNVEE-------GECVTSALCIPLASQK--RSSTGRPDW MICMUGS_2029_PE4 NOISO KW-YSDKGKEEM-FAVGWSGSLNVEE-------XXXXXXXXXXXXXXXXXXX--XXXXXX MONDO2_135_PE9 NOISO KWKYSDKGKEEMQYAVGWSGSLNVEE-------GECVSSALCIPLASQK--RSSTGRPDW MOUSE1_PE2676 NOISO KWKHGDKGKEEMQFAVGWSGSVSAEE-------GEYVTSALCIPLASQK--RSSTGRPDW MYOLUGS_5684_PE5 NOISO KWKYSDKGKEEMQFAVGWSGSLNVEE-------GEHVTSALCIPLASQK--RSSTGRPDW NEMVE_3145_PE41 NOISO KWDKSADD-PKNKYEVMWSGSLAVED-------GECVNDILCIPLASQH--KSSQGCPDW OCHPRGS_319_PE2 NOISO NGKYSDKRKEEMQFAVGWSGPPNVEE-------RECVTSALCIPLASQK--RSSTGRPDW ORNANULTRA67_7_PE11 ISOFORMIN KWKYSDKGKEEMQYAVGWSGSLNVEE-------GECVSSALCIPLASQK--RSSTGRPDW ORNANULTRA67_7_PE12 ENSOANG00000001428 KWKYSDKGKEEMQYAVGWSGSLNVEE-------GECVSSALCIPLASQK--RSSTGRPDW ORYLA22_21_PE9 NOISO KWRTDESGREEMTLGLSWSGTLSTEE-------GECVSSAIAIPLASQK--RSSTGRPDW OTOGAGS_376_PE2 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXX--XXXXXXXXX PANTR1_209_PE7 NOISO KWKYSDKGKEEMQFAVGWSGSLNVEE-------GECVTSALCIPLASQK--RSSTGRPDW PIG10_10_PE9 NOISO KWKHSDKGKEEMHFAVGWSGCLNVEE-------GEYVTSALCIPLASQK--RSSTGRPDW POEGU3_10_PE6 NOISO KWKHSDKGKEEMQYAVGWSGSLNVEE-------GECVSSVLCVPLASQK--RSSTGRPDW PONPY1_32_PE1 NOISO KWKYSDKGKEEMQFAVGWSGSLNVEE-------GECVTSALCIPLASQK--RSSTGRPDW PTEVA294_PE5 NOISO KWKYSDKGKEEMQFAVSWSGSLNVEE-------GEYVTSALCIPLASQK--RSSTGRPDW RABIT16_55_PE9 NOISO KWKYSDKGKEEMQFAVGWSGSLNVEE-------GECVTSALCIPLASQK--RSSTGRPDW RAT13_PE910 ENSRNOG00000002353 KWKHSDKGKEEMQFAVGWSGSVSAEE-------GEYVTSALCIPLASQK--RSSTGRPDW RAT13_PE911 ISOFORMIN KWKHSDKGKEEMQFAVGWSGSVSAEE-------GEYVTSALCIPLASQK--RSSTGRPDW SORARGS_484_PE2 NOISO KWKHSDKGKEEMQFAVGWSGSLNVED-------GECVTSALCIPLASQK--RSSTGRPDW STRPU_68668_PE1 NOISO KWDPEEKDGVDNKYHIIYKGMLNQEE-------GECITCAMCVPLASQK--RSSHGAPDW TARSYGS_3794_PE4 NOISO KWKYSDKGKEEMQFAVGWSGSLNVEE-------GECVTSALCIPLASQK--RSSTGRPDW TUPGBGS_5421_PE5 NOISO KWKYGDKGKEEMQFAVGWSGCLNVEE-------GERVTSALCIPLASQK--RSSTGRPDW TURTRGS_3295_PE5 NOISO KWKHSDKGKEEMQFAVGWSGSLSVEE-------GECVTSALCIPLASQK--RSSTGRPDW XENTR182_1_PE3 ENSXETG00000002728 KWKGSGKGKEEMQYEVVWSGSLTVEDGFLTIEDSECISSALCIPLASQK--RSSTGRPDW XENTR182_1_PE4 ISOFORMIN KWKGSGKGKEEMQYEVVWSGSLTVEDGFLTIEDSECISSALCIPLASQK--RSSTGRPDW XENTR182_1_PE5 ISOFORMIN KWKGSGKGKEEMQYEVVWSGSLTVEDGFLTIEDSECISSALCIPLASQK--RSSTGRPDW MATCH CONSENSUS KW?????G?EEM???V?WSG?L??E????????GE???S??CIPLASQK??RSSTGRPDW

AILMEGL192719_1_1_PE6 NOISO TCIVVGFTSGYVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP BOVINUN_004_2_2_PE6 NOISO TCIVVGFTSGYVRFYTENGVLLLAQLLNEDSVLQLKCRTYEIPRHPGVTEQNEELSILYP CALJA19_5_PE11 ENSCJAG00000011310 TCIVVGFTSGYVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP CANFA38_19_PE6 NOISO TCIVVGFTSGYVRFYTENGVLLLAQLLNEELVLQLKCRTYEIPRHPGVTEQNEELSILYP CAVPO13_3_PE5 NOISO TCIVVGFTSGYVRFYTENGVLLLAQLLHEDTVLQLKCRTYAIPRHPGVAEQNEELSILYP CHICK3_PE373 NOISO TCIVVGFTSGYVRFYTESGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP DANRE17_27_PE32 ISOFORMIN TCIVVGFSSGYVRFYTESGVLLLAQLLHEDPVLRLKCRTYEIPRHPGVTEQHEELSILYP DANRE17_27_PE33 ISOFORMIN TCIVVGFSSGYVRFYTE--------LLHEDPVLRLKCRTYEIPRHPGVTEQHEELSILYP DANRE17_27_PE34 ENSDARG00000044136 TCIVVGFSSGYVRFYTESGVLLLAQLLHEDPVLRLKCRTYEIPRHPGVTEQHEELSILYP DASNOGS_2270_PE1 NOISO TCIVVGFTSGYVRFYTENGVLLLAQLLNEDAVLQLKCRTYEIPRHPGVTEQNEELSILYP DIPORGS_4557_PE3 NOISO XXXXXXXXXXXXXXXXXNGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP ECHTEGS_570_PE2 NOISO TCIVVGFTSGYVRFYTENGVLLLAQLLNEDRVLQLKCRTYEIPRHPGVTEQNEELSILYP ERIEUGS_609_PE2 NOISO TCIVVGFTSGYVRFYTENGVLLLAQLLNEDLVLQLKCRTYEIPRHPGVTEQNEELSILYP FELCAGS_2186_PE3 NOISO TCIVVGFTSGYVRFYTENGVLLLAQLLNEDSVLQLKCRTYEIPRHPGVTEQNEELSILYP FUGRU517_PE13 ENSTRUG00000005143 TCVVVGFTTGYVRFYTENGVLLLSQLLQEDPVLRLKCRTYEIPLHPGITEQHEELSILYP FUGRU517_PE14 ISOFORMIN TCVVVGFTTGYVRFYTE--------LLQEDPVLRLKCRTYEIPLHPGITEQHEELSILYP FUGRU517_PE15 ISOFORMIN TCVVVGFTTGYVRFYTENGVLLLSQLLQEDPVLRLKCRTYEIPLHPGITEQHEELSILYP FUGRU517_PE16 ISOFORMIN TCVVVGFTTGYVRFYTENGVLLLSQLLQEDPVLRLKCRTYEIPLHPGITEQHEELSILYP GASACGROUPXV_17_PE10 ISOFORMIN TCVVVGFTSGHVRFYTE--------LLHEDPVLRLKCRTYEIPRHPGVTEQHEELSILYP GASACGROUPXV_17_PE11 ENSGACG00000013319 TCVVVGFTSGHVRFYTESGVLLLAQLLHEDPVLRLKCRTYEIPRHPGVTEQHEELSILYP GORGO1_206_PE8 ENSGGOG00000013163 TCIVVGFTSGCVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP GORGO1_206_PE9 ISOFORMIN TCIVVGFTSGCVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP HS1_PE6877 ENSG00000118873 TCIVVGFTSGYVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP LAMPAGS_245_2_PE5 NOISO TCIVVGFTSGYVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP LOXAF74_9_PE6 ENSLAFG00000011101 TCIVVGFTSGYVRFYTESGVLLLAQLLNEDPVLQLRCRTYEIPRHPGVTEQNEELSILYP LOXAF74_9_PE7 ISOFORMIN TCIVVGFTSGYVRFYTE-GVLLLAQLLNEDPVLQLRCRTYEIPRHPGVTEQNEELSILYP MACEUGS_3247_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXX MACMU1_155_PE12 ENSMMUG00000007784 TCIVVGFTSGYVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP MACMU1_155_PE14 ISOFORMIN TCIVVGFTSGYVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP MICMUGS_2029_PE4 NOISO XXXXXXXXXXXXXXXXXNGVLLLAQLLNEDA-LQLKCRTYEIPRHPGVTEQNEELSILYP MONDO2_135_PE9 NOISO TCIVVGFTSGYVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP MOUSE1_PE2676 NOISO TCIVVGFTSGYVRFYTE-GVLLLAQLLNEDKVLQLKCRTYEIPRHPGVTEQNEELSILYP MYOLUGS_5684_PE5 NOISO TCIVLGFTSGSVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP NEMVE_3145_PE41 NOISO TCIIAGMTSGYMRIYLQNGSLMFSQLLHEDYVVRLKCRTWQPYRSFGKVEQGS---VLYP OCHPRGS_319_PE2 NOISO TCIVVGFTSGYVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP ORNANULTRA67_7_PE11 ISOFORMIN TCIVVGFTSGYVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP ORNANULTRA67_7_PE12 ENSOANG00000001428 TCIVVGFTSGYVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP ORYLA22_21_PE9 NOISO TCVVVGFTSGYVRFYTEGGVLLLAQLLHEDPVLRLKCRTYEIPRHPGVAEQHEELSILYP OTOGAGS_376_PE2 NOISO XXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXX PANTR1_209_PE7 NOISO TCIVVGFTSGYVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP PIG10_10_PE9 NOISO TCIVVGFSSGYLRFYTQNGVLLLAQLLNEDLVLQLKCRTYEIPRHPGVTEQNEELSILYP POEGU3_10_PE6 NOISO TCIVVGFTSGYVRFYTESGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP PONPY1_32_PE1 NOISO TCIVVGFTSGYVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP PTEVA294_PE5 NOISO TCIVVGFTSGYVRFYTESGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP RABIT16_55_PE9 NOISO TCIVVGFTSGYVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP RAT13_PE910 ENSRNOG00000002353 TCIVVGFTSGYVRFYTESGVLLLAQLLNEDRVLQLKCRTYEIPRHPGVTEQNEELSILYP RAT13_PE911 ISOFORMIN TCIVVGFTSGYVRFYTESGVLLLAQLLNEDRVLQLKCRTYEIPRHPGVTEQNEELSILYP SORARGS_484_PE2 NOISO TCIVVGFTSGYVRFYTENGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP STRPU_68668_PE1 NOISO TCVVLGFTSGYVRMYTETGSLLLSQLLHEDPVLKLKGRTYEMPRHAGVAEQQEELTILYP TARSYGS_3794_PE4 NOISO TCIVVGFTSGYVRFYTESGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP TUPGBGS_5421_PE5 NOISO TCIVVGFTSGYVRFYTESGVLLLAQLLNEDPVLQLKCRTYEIPRHPGVTEQXXXXXXXXX TURTRGS_3295_PE5 NOISO TCIVVGFTSGYVRFYTESGVLLLSQLLNEDPVLQLKCRTYEIPRHPGVTEQNEELSILYP XENTR182_1_PE3 ENSXETG00000002728 TCIVFGFTSGYVRFYTESGVLLLSQLLNQEAVLQLKCRTYEVPRHPGVTEQHEEMSLLYP XENTR182_1_PE4 ISOFORMIN TCIVFGFTSGYVRFYTESGVLLLSQLLNQEAVLQLKCRTYEVPRHPGVTEQHEEMSLLYP XENTR182_1_PE5 ISOFORMIN TCIVFGFTSGYVRFYTE--------LLNQEAVLQLKCRTYEVPRHPGVTEQHEEMSLLYP MATCH CONSENSUS TC?VVGFTSGYVRFYTE?GVLLL?QLL?ED?VL?LKCRTYEIPRHPGVTEQ?EELSILYP

AILMEGL192719_1_1_PE6 NOISO VAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS BOVINUN_004_2_2_PE6 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS CALJA19_5_PE11 ENSCJAG00000011310 AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS CANFA38_19_PE6 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS CAVPO13_3_PE5 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GSESVQPPPLAYKKWGLQDTDIIVDHAS CHICK3_PE373 NOISO AAIVTIDGFSLFQSLRACRNQVAR---AAAS-GNENVQPPPLAYKKWGLQDVDTIVDHAS DANRE17_27_PE32 ISOFORMIN AALVTIDGFSLFQSLRACRNQVAR---AAAA-GSDVIQPPPLAYKKWGLQDMDTIADHSS DANRE17_27_PE33 ISOFORMIN AALVTIDGFSLFQSLRACRNQVAR---AAAA-GSDVIQPPPLAYKKWGLQDMDTIADHSS DANRE17_27_PE34 ENSDARG00000044136 AALVTIDGFSLFQSLRACRNQVAR---AAAA-GSDVIQPPPLAYKKWGLQDMDTIADHSS DASNOGS_2270_PE1 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENVQPPPLAYKKWGLQDIDTIIDHAS DIPORGS_4557_PE3 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS ECHTEGS_570_PE2 NOISO AAIVTIDGFSLFQSLRACRNQVAKXXXXXXX-XXXXXXXXX----XXXXXXXXXXXXXXX ERIEUGS_609_PE2 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLLDIDTIIDHAS FELCAGS_2186_PE3 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS FUGRU517_PE13 ENSTRUG00000005143 TALVTIDGFSLFQSLRACRNQVAR---AAAA-GSDVIQPPPLAYKKWGLQDMDTIVDHSS FUGRU517_PE14 ISOFORMIN TALVTIDGFSLFQSLRACRNQVAR---AAAA-GSDVIQPPPLAYKKWGLQDMDTIVDHSS FUGRU517_PE15 ISOFORMIN TALVTIDGFSLFQSLRACRNQVAR---AAAA-GSDVIQPPPLAYKKWGLQDMDTIVDHSS FUGRU517_PE16 ISOFORMIN TALVTIDGFSLFQSLRACRNQVAR---AAAA-GSDVIQPPPLAYKKWGLQDMDTIVDHSS GASACGROUPXV_17_PE10 ISOFORMIN AALVTIDGFSLFQSLRACRNQVAR---ATAA-GSDVIQPPPLAYKKWALQDMDTIVDHSS GASACGROUPXV_17_PE11 ENSGACG00000013319 AALVTIDGFSLFQSLRACRNQVAR---ATAA-GSDVIQPPPLAYKKWALQDMDTIVDHSS GORGO1_206_PE8 ENSGGOG00000013163 AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS GORGO1_206_PE9 ISOFORMIN AAIVTIDGFSLFQSLRACRNQVAKALEAAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS HS1_PE6877 ENSG00000118873 AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS LAMPAGS_245_2_PE5 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS LOXAF74_9_PE6 ENSLAFG00000011101 AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTVIDHAS LOXAF74_9_PE7 ISOFORMIN AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTVIDHAS MACEUGS_3247_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXX---XXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX MACMU1_155_PE12 ENSMMUG00000007784 AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS MACMU1_155_PE14 ISOFORMIN AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS MICMUGS_2029_PE4 NOISO AAIVTIDGFSLFQSLRACRNQVAKXXXXXXX-XXXXXXX---XXXXXXXXXXXXXXXHAS MONDO2_135_PE9 NOISO AAIVTIDGFSLFQSLRACRNQVAK---ATAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS MOUSE1_PE2676 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS MYOLUGS_5684_PE5 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDVDTIVDHAS NEMVE_3145_PE41 NOISO LVSSRLISSNSPYSLRSKRSHSVCLVSAQASGMQDLIQPPPLAYKKWRFDGQKHITDIAS OCHPRGS_319_PE2 NOISO GAIVTIDGFSLFQSLRACRNQVAK---ATAS-GNEHIQPPPLAYKKWGLQDIDTIIDHAS ORNANULTRA67_7_PE11 ISOFORMIN AAIVTIDGFSLFQSLRACRNQVAR---AAAS-GNENIQPPPLAYKKWGLQDVDTIIDHAA ORNANULTRA67_7_PE12 ENSOANG00000001428 AAIVTIDGFSLFQSLRACRNQVAR---AAAS-GNENIQPPPLAYKKWGLQDVDTIIDHAA ORYLA22_21_PE9 NOISO AAMVTIDGFSLFQSLRACRNQVAR---ATAA-GSDVVPPPPLAYKKWGLQEMDSIVDHSS OTOGAGS_376_PE2 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS PANTR1_209_PE7 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS PIG10_10_PE9 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS POEGU3_10_PE6 NOISO AAIVTIDGFSLFQSLRACRNQVAR---AAAS-GNENVQPPPLAYKKWGLQDVDMIVDHAS PONPY1_32_PE1 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS PTEVA294_PE5 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS RABIT16_55_PE9 NOISO AAIVTIDGFSLFQSLRACRNQVAK---ATAS-GNEHIQPPPLAYKKWGLQDIDTIIDHAS RAT13_PE910 ENSRNOG00000002353 AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS RAT13_PE911 ISOFORMIN AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS SORARGS_484_PE2 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS STRPU_68668_PE1 NOISO TALVTVDGFSLFQSLRACRNQLAK---AAAS-GSDNILPPPLAYKKWGLQQQDAIVDHIS TARSYGS_3794_PE4 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS TUPGBGS_5421_PE5 NOISO XXXXXXXXXX---XXXXXXXXXXXXXXXAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS TURTRGS_3295_PE5 NOISO AAIVTIDGFSLFQSLRACRNQVAK---AAAS-GNENIQPPPLAYKKWGLQDIDTIIDHAS XENTR182_1_PE3 ENSXETG00000002728 SAVVTIDGFSLFQSLRACRNQVAR---AAAS-GSENVQPPPLAYKKWGLQDVDRIVDHAS XENTR182_1_PE4 ISOFORMIN SAVVTIDGFSLFQSLRACRNQVAR---AAAS-GSENVQPPPLAYKKWGLQDVDRIVDHAS XENTR182_1_PE5 ISOFORMIN SAVVTIDGFSLFQSLRACRNQVAR---AAAS-GSENVQPPPLAYKKWGLQDVDRIVDHAS MATCH CONSENSUS ?A?VTIDGFSLFQSLRACRNQVA????AAA??G???IQPPPLAYKKWGLQD?DTI?DH?S

AILMEGL192719_1_1_PE6 NOISO -IGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS BOVINUN_004_2_2_PE6 NOISO -IGIMTLSPFDQMKTASNIGGYNAAIKNSPPAMSQYITVGSSPFTGFFYALEGSTQPLLS CALJA19_5_PE11 ENSCJAG00000011310 -VGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS CANFA38_19_PE6 NOISO -IGIMTLSPFDQMKTASNIGGFNAAIKNSLPAMSQYITVGSNPFTGFFYALEGSTQPLLS CAVPO13_3_PE5 NOISO -IGITTLSPFDQMKTASNIGGFNATIKPSPPAMSQYITVGANPFTGFFYALEGSTQPLLS CHICK3_PE373 NOISO -VGIMTLSPFDQMKTASNIGGYNAAIKNSPPAMSQYVTVGSNPFTGFFFALEGSSQPLLS DANRE17_27_PE32 ISOFORMIN -IGITTLSVFDQMKNASILGGFHASVKGSPPAMSQYITVGGGPYTGFFYAIEGSSQPLLS DANRE17_27_PE33 ISOFORMIN -IGITTLSVFDQMKNASILGGFHASVKGSPPAMSQYITVGGGPYTGFFYAIEGSSQPLLS DANRE17_27_PE34 ENSDARG00000044136 -IGITTLSVFDQMKNASILGGFHASVKGSPPAMSQYITVGGGPYTGFFYAIEGSSQPLLS DASNOGS_2270_PE1 NOISO -VGIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX DIPORGS_4557_PE3 NOISO -IGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS ECHTEGS_570_PE2 NOISO XXXIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS ERIEUGS_609_PE2 NOISO -IGIMTLSPFDQMKTASNIGGYNATIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS FELCAGS_2186_PE3 NOISO -IGIMTLSPFDQMKTASNVGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS FUGRU517_PE13 ENSTRUG00000005143 -VGIMTLCVFDQMKNASILGGFNASVKGSPPAMSLYVSVGGGPYIGFYYAVEGSSQPLLS FUGRU517_PE14 ISOFORMIN -VGIMTLCVFDQMKNASILGGFNASVKGSPPAMSLYVSVGGGPYIGFYYAVEGSSQPLLS FUGRU517_PE15 ISOFORMIN -VGIMTLCVFDQMKNASILGGFNASVKGSPPAMSLYVSVGGGPYIGFYYAVEGSSQPLLS FUGRU517_PE16 ISOFORMIN -VGIMTLCVFDQMKNASILGGFNASVKGSPPAMSLYVSVGGGPYIGFYYAVEGSSQPLLS GASACGROUPXV_17_PE10 ISOFORMIN -VGIMTLCVFDQMKNASVLGGFNASVKGSPPAMSQYVTVGGGPYTGFYYAVEGSSQPLLS GASACGROUPXV_17_PE11 ENSGACG00000013319 -VGIMTLCVFDQMKNASVLGGFNASVKGSPPAMSQYVTVGGGPYTGFYYAVEGSSQPLLS GORGO1_206_PE8 ENSGGOG00000013163 -VGIMTLSAFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS GORGO1_206_PE9 ISOFORMIN VVGIMTLSAFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS HS1_PE6877 ENSG00000118873 -VGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS LAMPAGS_245_2_PE5 NOISO -IGIMTLSAFDQMKTASNIGGFNATIKNSPPAMSQYITVGSSPFTGFFYALEGSTQPLLS LOXAF74_9_PE6 ENSLAFG00000011101 -IGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSSPFTGFFYALEGSTQPLLS LOXAF74_9_PE7 ISOFORMIN -IGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSSPFTGFFYALEGSTQPLLS MACEUGS_3247_PE1 NOISO XXXIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEXXXXXXXX MACMU1_155_PE12 ENSMMUG00000007784 -VGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS MACMU1_155_PE14 ISOFORMIN -VGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS MICMUGS_2029_PE4 NOISO -VGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS MONDO2_135_PE9 NOISO -IGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSSQPLLS MOUSE1_PE2676 NOISO -IGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSSPFTGFFYALEGSTQPLLS MYOLUGS_5684_PE5 NOISO -IGIMTLSPFDQMKTSNIXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXGSTQPLLS NEMVE_3145_PE41 NOISO -CGVVTQNMFDQLQTASFIGGYNAVIRTSAPAMSHYVASGADPFLAVYCAIEGSGPPLIS OCHPRGS_319_PE2 NOISO -IGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGANPFTGFFYALEGSTQPLLS ORNANULTRA67_7_PE11 ISOFORMIN -LGIMTLSPFDQMKTASNIGGFNATIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS ORNANULTRA67_7_PE12 ENSOANG00000001428 -LGIMTLSPFDQMKTASNIGGFNATIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS ORYLA22_21_PE9 NOISO -IVTNLG-V-KPPPRLRTMG-DNTAFCSAAPRLWNSLPVHSLPVKCNFYSFKGSSQPLLS OTOGAGS_376_PE2 NOISO VXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX PANTR1_209_PE7 NOISO -VGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS PIG10_10_PE9 NOISO -IGIMTLSPFDQMKTASNIGGYNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS POEGU3_10_PE6 NOISO -IGIMTLCPFDQMKTASNIGGYNAAIKNSPPAMSQYVTVGANPFTGFFFALEGSSQPLLS PONPY1_32_PE1 NOISO -VGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSSPFTGFFYALEGSTQPLLS PTEVA294_PE5 NOISO -IGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS RABIT16_55_PE9 NOISO -IGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS RAT13_PE910 ENSRNOG00000002353 -IGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSSPFTGFFYALEGSTQPLLS RAT13_PE911 ISOFORMIN -IGIMTLSPFDQMKTASNIGGFNAAIKNSPPAMSQYITVGSSPFTGFFYALEGSTQPLLS SORARGS_484_PE2 NOISO -IGIMTLTPFDQMKTASNIGGYNAAIKNSLPAMSQYITVGSNPFTGFFYALEGSTQPLLS STRPU_68668_PE1 NOISO -TGVVTSYSFDQLHAASTLGGYNASIKKSPPICHKYITTGAGPFLGFFYALEGSAQPLFS TARSYGS_3794_PE4 NOISO VXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXGSTQPLLS TUPGBGS_5421_PE5 NOISO IXXX-XXXXXXXXXXXXXIGGFNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSSQPLLS TURTRGS_3295_PE5 NOISO -IGIMTLSPFDQMKTASNIGGYNAAIKNSPPAMSQYITVGSNPFTGFFYALEGSTQPLLS XENTR182_1_PE3 ENSXETG00000002728 -VGVMALSPFDQMKTASILGGFNAAIKSSPPTMSQYITVGSNPFTGFFFALEGSTQPLLS XENTR182_1_PE4 ISOFORMIN -VGVMALSPFDQMKTASILGGFNAAIKSSPPTMSQYITVGSNPFTGFFFALEGSTQPLLS XENTR182_1_PE5 ISOFORMIN -VGVMALSPFDQMKTASILGGFNAAIKSSPPTMSQYITVGSNPFTGFFFALEGSTQPLLS MATCH CONSENSUS ??GIMTL??FDQMK?AS??GG?NA??K?SPPAMSQY?TVG??P?TGFFYA?EGS?QPLLS

AILMEGL192719_1_1_PE6 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAVRIRFG BOVINUN_004_2_2_PE6 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAFQK---QKPKVEPATPLAV--RFG CALJA19_5_PE11 ENSCJAG00000011310 HVALAVASKLTSALFNA-A--SGWLGWKGKHEE-EAVQK---QKPKVEPATPLAV--RFG CANFA38_19_PE6 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAV--RFG CAVPO13_3_PE5 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QRPKVEPATPLAV--RFG CHICK3_PE373 NOISO HVALAVASKLTSALFHA-ASVSGWLGWKSKHEE-EPVQK---QKPKVEPATPLAV--RFG DANRE17_27_PE32 ISOFORMIN HVALAVASKLTSALFSA---ASGWLGWKS-KNEEESVQK---QKPKVEPATALPV--RFG DANRE17_27_PE33 ISOFORMIN HVALAVASKLTSALFSA---ASGWLGWKS-KNEEESVQK---QKPKVEPATALPV--RFG DANRE17_27_PE34 ENSDARG00000044136 HVALAVASKLTSALFSA---ASGWLGWKS-KNEEESVQK---QKPKVEPATALPV--RFG DASNOGS_2270_PE1 NOISO XXX--XXXXXXXXXXXX-X--XXXXXXXXXXXX-XXXXX---XXXXXXXXXXXXXXXXFG DIPORGS_4557_PE3 NOISO HVALAVASKLTSALFNA-A--XXXXXXXXXXXX-XXXXX-----XXXXXXXXXXXXXXFG ECHTEGS_570_PE2 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAV--RFG ERIEUGS_609_PE2 NOISO HVALAVASKLTSALFNA-A--XXXXXXXXXXXX-XXXX-----XXXXXXXXXXXXXXXFG FELCAGS_2186_PE3 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EVVPK---QKPKVEPAAPLAV--XXX FUGRU517_PE13 ENSTRUG00000005143 HVALAVASKLTSALFNA---ASGWLGWNKNRSEEETVQK---QKPKVEPATPLGI--RFG FUGRU517_PE14 ISOFORMIN HVALAVASKLTSALFNA---ASGWLGWNKNRSEEETVQK---QKPKVEPATPLGI--RFG FUGRU517_PE15 ISOFORMIN HVALAVASKLTSALFNA---ASGWLGWNKNRSEEETVQK---QKPKVEPATPLGI--RFG FUGRU517_PE16 ISOFORMIN HVALAVASKLTSALFNA---ASGWLGWNKNRSEEETVQK---QKPKVEPATPLGI--RFG GASACGROUPXV_17_PE10 ISOFORMIN HVALAVASKLTSALFSA---ASGWLGWNRHKNEEEAVQK---QKPKVEPATPLGI--RFG GASACGROUPXV_17_PE11 ENSGACG00000013319 HVALAVASKLTSALFSA---ASGWLGWNRHKNEEEAVQK---QKPKVEPATPLGI--RFG GORGO1_206_PE8 ENSGGOG00000013163 HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAV--RFG GORGO1_206_PE9 ISOFORMIN HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAV--RFG HS1_PE6877 ENSG00000118873 HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAV--RFG LAMPAGS_245_2_PE5 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSRHEE-EAVQK---QKPKVEPATPLAV--RFG LOXAF74_9_PE6 ENSLAFG00000011101 HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAIQR---QKPKVEPATPLAV--RFG LOXAF74_9_PE7 ISOFORMIN HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAIQR---QKPKVEPATPLAV--RFG MACEUGS_3247_PE1 NOISO XXXXXXXXXXXXXXXXX-X----XXXXXXXXXX-XXXXX---XXXXXXXXXXXXXXXXFG MACMU1_155_PE12 ENSMMUG00000007784 HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAV--RFG MACMU1_155_PE14 ISOFORMIN HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAV--LFG MICMUGS_2029_PE4 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAV--RFG MONDO2_135_PE9 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-ENVQK---QKPKVEPATPLAV--RFG MOUSE1_PE2676 NOISO HVALAVASKLTSALFSA-A--SGWLGWKSKHEE-DTVQK---QKPKMEPATPLAV--RFG MYOLUGS_5684_PE5 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSRHEE-EAVQK---QKPKMEPATPLAV--RFG NEMVE_3145_PE41 NOISO DVAMAVASKLTSAVLSRLSAASGWLGWGSKPAA-QPAEQTKPPKPKVEKGAKLAA--RFG OCHPRGS_319_PE2 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAV--RFG ORNANULTRA67_7_PE11 ISOFORMIN HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAV--RFG ORNANULTRA67_7_PE12 ENSOANG00000001428 HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAV--RFG ORYLA22_21_PE9 NOISO HVAMAVASKLTSALFSA---ASGWLGWNKSKTEEDSTPK---QRPKVEPATPLGI--RFG OTOGAGS_376_PE2 NOISO XXXXXXXXXXXXXLFNA-A--SGWLGWKGKHEE-EAVQK---QKPKVEPATPLAV--RFG PANTR1_209_PE7 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAV--RFG PIG10_10_PE9 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVPR---QKPKVEPATPLAV--RFG POEGU3_10_PE6 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EPVQK---QKPKVEPATPLAV--RFG PONPY1_32_PE1 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAV--RFG PTEVA294_PE5 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-ETVQK---QKPKLEPATPLAV--RFG RABIT16_55_PE9 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAV--RFG RAT13_PE910 ENSRNOG00000002353 HVALAVASKLTSALFSA-A--SGWLGWKSKHEE-ETVQK---QKPKMEPATPLAV--RFG RAT13_PE911 ISOFORMIN HVALAVASKLTSALFSA-A--SGWLGWKSKHEE-ETVQK---QKPKMEPATPLAV--RFG SORARGS_484_PE2 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAFQK---QKPKVEPATPLAV--RFG STRPU_68668_PE1 NOISO DVALAVASKLKSAIFSA---ASGWFGFGGNKQTTDTPAPSKTSKPRVEPAISLPI--RFG TARSYGS_3794_PE4 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAIQK---QKPKVEPATPLAV--RFG TUPGBGS_5421_PE5 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-ETVQK---HKPKVEPATPLAV--RFG TURTRGS_3295_PE5 NOISO HVALAVASKLTSALFNA-A--SGWLGWKSKHEE-EAVQK---QKPKVEPATPLAV--RFG XENTR182_1_PE3 ENSXETG00000002728 HVALAVASKLTSALFSA-A--SGWLGWKSKHEE-EPQQK---QKPKVEPANPLAV--RFG XENTR182_1_PE4 ISOFORMIN HVALAVASKLTSALFSA-A--SGWLGWKSKHEE-EPQQK---QKPKVEPANPLAV--RFG XENTR182_1_PE5 ISOFORMIN HVALAVASKLTSALFSA-A--SGWLGWKSKHEE-EPQQK---QKPKVEPANPLAV--RFG MATCH CONSENSUS HVALAVASKLTSALF?A????SGWLGW?????E?E??QK???QKPKVEPATPL????RFG

AILMEGL192719_1_1_PE6 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWKGLQGYRDAQIGWIQIV BOVINUN_004_2_2_PE6 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQTGWIQIV CALJA19_5_PE11 ENSCJAG00000011310 LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQIGWIQVV CANFA38_19_PE6 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQIGWIQIV CAVPO13_3_PE5 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVTRGIAVRMWK---GYRDAQVGWAQIV CHICK3_PE373 NOISO IPDSRRHGEKICLSPCNTLAAVTDDFGRVILLDVTRGLAIRMWK---GYRDAEVGWIQTV DANRE17_27_PE32 ISOFORMIN LPDSRRHGESICLSPCNTMAGVTDDFGRVTLLDVARGIAIRMWK---GYRDAQLGWVQVS DANRE17_27_PE33 ISOFORMIN LPDSRRHGESICLSPCNTMAGVTDDFGRVTLLDVARGIAIRMWK---GYRDAQLGWVQVS DANRE17_27_PE34 ENSDARG00000044136 LPDSRRHGESICLSPCNTMAGVTDDFGRVTLLDVARGIAIRMWK---GYRDAQLGWVQVS DASNOGS_2270_PE1 NOISO LPDSRRHGESLCLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQIGWIQIV DIPORGS_4557_PE3 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVTRGIAIRMWK---GYRDAQIGWIQIV ECHTEGS_570_PE2 NOISO LPDSRRHGESICLSPCNTLAAATDDFGRVILLDVARGIAVRMWK---GYRDAQIGWIQIV ERIEUGS_609_PE2 NOISO LPDSRRHGESICLSPCNSLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQLGWIQIV FELCAGS_2186_PE3 NOISO XXXXRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQIGWMQIV FUGRU517_PE13 ENSTRUG00000005143 LPDSRRHGESICLSPCNMLAGVTDDFGRVALLDLARGICIRMWK---GYRDAQLGWLQVQ FUGRU517_PE14 ISOFORMIN LPDSRRHGESICLSPCNMLAGVTDDFGRVALLDLARGICIRMWK---GYRDAQLGWLQVQ FUGRU517_PE15 ISOFORMIN LPDSRRHGESICLSPCNMLAGVTDDFGRVALLDLARGICIRMWK---GYRDAQLGWLQVQ FUGRU517_PE16 ISOFORMIN LPDSRRHGESICLSPCNMLAGVTDDFGRVALLDLARGICIRMWK---GYRDAQLGWLQVQ GASACGROUPXV_17_PE10 ISOFORMIN LPDSRRHGESVCLSPCNTLAGVTDDFGRVTLLDLARGIAIRMWK---GYRDAQLGWLQVP GASACGROUPXV_17_PE11 ENSGACG00000013319 LPDSRRHGESVCLSPCNTLAGVTDDFGRVTLLDLARGIAIRMWK---GYRDAQLGWLQVP GORGO1_206_PE8 ENSGGOG00000013163 LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQIGWIQIV GORGO1_206_PE9 ISOFORMIN LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQIGWIQIV HS1_PE6877 ENSG00000118873 LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQIGWIQTV LAMPAGS_245_2_PE5 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQTGWIQIV LOXAF74_9_PE6 ENSLAFG00000011101 LPDSRRHGESICLSPCNTLAAATDDFGRVILLDVARGIAIRMWK---GYRDAQVGWIQVV LOXAF74_9_PE7 ISOFORMIN LPDSRRHGESICLSPCNTLAAATDDFGRVILLDVARGIAIRMWK---GYRDAQVGWIQVV MACEUGS_3247_PE1 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGLAIRMWK---GYRDAQIGWIQIV MACMU1_155_PE12 ENSMMUG00000007784 LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQIGWIQIV MACMU1_155_PE14 ISOFORMIN LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQIGWIQIV MICMUGS_2029_PE4 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWKXX---XXXXXXXXXXV MONDO2_135_PE9 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGLAIRMWK---GYRDAQIGWIQII MOUSE1_PE2676 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQVGWIQIV MYOLUGS_5684_PE5 NOISO LPDSRRHGESICLSPCNSLAAVTDDFGRVILLDVTRGIAIRMWK---GYRDAQIGWVQVV NEMVE_3145_PE41 NOISO LPDFPRRGTNITLAPNGKVAVTTDEFGRVMLLDVKKGIAIRMWK---GYREAECGWIMVD OCHPRGS_319_PE2 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAVRMWK---GYRDAQIGWIQIV ORNANULTRA67_7_PE11 ISOFORMIN LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGLAIRMWK---GYRDAQIGWVQVI ORNANULTRA67_7_PE12 ENSOANG00000001428 LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGLAIRMWK---GYRDAQIGWVQVI ORYLA22_21_PE9 NOISO LPDSRRHGESICLSPCNTLAGVTDDFGRVTLLDLARGISIRMWK---GYRDAQLGWLQVR OTOGAGS_376_PE2 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYR-TQIGWXXXX PANTR1_209_PE7 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQIGWIQIV PIG10_10_PE9 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVTRGIAIRMWK---GYRDAQTGWIQIV POEGU3_10_PE6 NOISO LPDSRRHGERICLSPCNTLAAVTDEFGRVILLDVTRGLAVRMWK---GYRDAEVGWIQTV PONPY1_32_PE1 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQIGWIQIV PTEVA294_PE5 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQTGWTQVV RABIT16_55_PE9 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVSRGIAIRMWK---GYRDAQIGWIQIV RAT13_PE910 ENSRNOG00000002353 LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQIGWIQIV RAT13_PE911 ISOFORMIN LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIRMWK---GYRDAQIGWIQIV SORARGS_484_PE2 NOISO LPDSRRRGESICLSPCNTLAAVTDDFGRVILLDVSRGIAIRMWK---GYRDAQVGWIQIV STRPU_68668_PE1 NOISO LPDVRRHGDTIVLAPGMRLAASTDSFGRVSLIDVTRGVAVRMWK---GYRDAQCGWIQVI TARSYGS_3794_PE4 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDIARGIAIRMWK---GYRDAQIGWIQIV TUPGBGS_5421_PE5 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVTRGIAIRMWK---GYRDAQIGWIQIV TURTRGS_3295_PE5 NOISO LPDSRRHGESICLSPCNTLAAVTDDFGRIILLDVARGIAIRMWK---GYRDAQTGWIQIV XENTR182_1_PE3 ENSXETG00000002728 LPDSRRHGERVSLSPCNTLAAVTDDFGRVILLDVGRGIAIRMWK---GYRDAQVGWMQIV XENTR182_1_PE4 ISOFORMIN LPDSRRHGERVSLSPCNTLAAVTDDFGRVILLDVGRGIAIRMWK---GYRDAQVGWMQIV XENTR182_1_PE5 ISOFORMIN LPDSRRHGERVSLSPCNTLAAVTDDFGRVILLDVGRGIAIRMWK---GYRDAQVGWMQIV MATCH *:* : *:* :* **.***: *:*: :*:.:**** CONSENSUS LPDSRRHGESICLSPCNTLAAVTDDFGRV?LLDV?RGIAIRMWK???GYRDAQ?GW?Q??

AILMEGL192719_1_1_PE6 NOISO EDLHERVP-EKADFSPF--GNTQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK BOVINUN_004_2_2_PE6 NOISO EDLHERVP-EKGDFSPF--GSPQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK CALJA19_5_PE11 ENSCJAG00000011310 EDLHERVP-EKADFSPF--GNSQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK CANFA38_19_PE6 NOISO EDLHERVP-EKADFSPF--GNTQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK CAVPO13_3_PE5 NOISO EDLQERAP-DSTDGAPF--GSTQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK CHICK3_PE373 NOISO EDLHERET-EKIDYSPF--GNAQCPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK DANRE17_27_PE32 ISOFORMIN EARGERDIA----------TSPSMPRRHAQFLVIYAPRRGILEVWGTQHGPRVGAFTVGK DANRE17_27_PE33 ISOFORMIN EARGERDIA----------TSPSMPRRHAQFLVIYAPRRGILEVWGTQHGPRVGAFTVGK DANRE17_27_PE34 ENSDARG00000044136 EARGERDIA----------TSPSMPRRHAQFLVIYAPRRGILEVWGTQHGPRVGAFTVGK DASNOGS_2270_PE1 NOISO EDLHERVP-EKVDFSPF--GNTQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK DIPORGS_4557_PE3 NOISO EDLHERVP-EKVDFSPF--GNTQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK ECHTEGS_570_PE2 NOISO EDLHERVP-EKVDLSPF--GNTHGPSRVAQFLVIYAPRRGILEVWGTQQGPRVGAFNVGK ERIEUGS_609_PE2 NOISO EDLHERVA-EKVDLSPF--GNTQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK FELCAGS_2186_PE3 NOISO EDLHERVP-EKADFSPF--GNTQGPSRVAQFLVIYAPRRGILEVWGTQQGPRVGAFNVGK FUGRU517_PE13 ENSTRUG00000005143 EERGDHD-------------SSSLPKRHALFLVIYAPRRGILEVWAMKQGPRVGAFNVGK FUGRU517_PE14 ISOFORMIN EERGDHD-------------SSSLPKRHALFLVIYAPRRGILEVWAMKQGPRVGAFNVGK FUGRU517_PE15 ISOFORMIN EERGDHD-------------SSSLPKRHALFLVIYAPRRGILEVWAMKQGPRVGAFNVGK FUGRU517_PE16 ISOFORMIN EERGDHD-------------SSSLPKRHALFLVIYAPRRGILEVWAMKQGPRVGAFNVGK GASACGROUPXV_17_PE10 ISOFORMIN EERGDREFS----------PSASLPRRHALFLVIYAPRRGILEVWGMQQGPRVGAFTVGK GASACGROUPXV_17_PE11 ENSGACG00000013319 EERGDREFS----------PSASLPRRHALFLVIYAPRRGILEVWGMQQGPRVGAFTVGK GORGO1_206_PE8 ENSGGOG00000013163 EDLHERVP-EKADFSPF--GNSQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK GORGO1_206_PE9 ISOFORMIN EDLHERVP-EKADFSPF--GNSQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK HS1_PE6877 ENSG00000118873 EDLHERVP-EKADFSPF--GNSQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK LAMPAGS_245_2_PE5 NOISO EDLHERVP-EKGDFSPF--GSPQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK LOXAF74_9_PE6 ENSLAFG00000011101 EDLHER-P-EKVELSPF--GNTQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK LOXAF74_9_PE7 ISOFORMIN EDLHER-P-EKVELSPF--GNTQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK MACEUGS_3247_PE1 NOISO EDLHERES-EKMDFSPF--GNTQGPSRVAQFLVIYAPRRGILEVWSTQQGPRVGAFNVGK MACMU1_155_PE12 ENSMMUG00000007784 EDLHERVP-EKADFSPF--GNSQGPSRVAQFLVI