Alignment of the gene Family HBG000010 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
B1WBU2_RAT B1WBU2_RAT APRKPPPSPLRPCLQ---MKVDELFLRWLSDPGTQRALRAGLRRIQGPAVI-LDHTVTPN P2R3A_MOUSE P2R3A_MOUSE MPERPPIRALRRDPDDPAVAQALASLARGSDLVFPSRFQKWLRDFRQ------------- Q8K1A4_MOUSE Q8K1A4_MOUSE ------MAPLTPRLQ---LKVDELFRRWLGDPHTQRALSHALRRIRD------------- A6QNV9_BOVIN A6QNV9_BOVIN --MMIKETSLRRDPD---LRGELAFLARGCDFVLPSRFKKRLKSFQQ------------- B4DNU1_HUMAN B4DNU1_HUMAN ------------------------------------------------------------ B4DS28_HUMAN B4DS28_HUMAN --MMIKETSLRRDPD---LRGELAFLARGCDFVLPSRFKKRLKSFQQ------------- Q5PQN8_RAT Q5PQN8_RAT --MMIKETSLRRDPD---LRGELAFLARGCDFVLPSRFKKRLKSFQQ------------- Q3V1Y6_MOUSE Q3V1Y6_MOUSE --MMIKETSLRRDPD---LRGELAFLARGCDFVLPSRFKKRLKSFQQ------------- Q8BM38_MOUSE Q8BM38_MOUSE --MMIKETSLRRDPD---LRGELAFLARGCDFVLPSRFKKRLKSFQQ------------- A1L2R4_XENLA A1L2R4_XENLA --MMIKEASLRIDPD---LRGELAFLARGCDFVLPSRFKKRIKSFQQ------------- A7UNT4_CARAU A7UNT4_CARAU ------------------------------------------------------------ B0S5Q0_DANRE B0S5Q0_DANRE --MMIKEASLREDPD---LRGELAFLARGCDFVLPSRFKKRLKSFQQ------------- P2R3B_HUMAN P2R3B_HUMAN ---MPPGKVLQPVLK---MKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQ Q96FD8_HUMAN Q96FD8_HUMAN ------------------------------------------------------------ Q9UHL2_HUMAN Q9UHL2_HUMAN ------------------------------------------------------------ Q498G0_XENLA Q498G0_XENLA ------------------------------------------------------------ Q08D09_XENTR Q08D09_XENTR ---MPTTTVLKPVLK---MKVDELFLRWLSETPTQLLLNDYLRRIKNGEKI-LPDADDYG A1A5J1_XENLA A1A5J1_XENLA ---MPTTTVLKPVLK---MKVDELFLRWLSETPTQLLLNDYLRRIKNGEKI-LPETDDYG Q7T3S1_XENLA Q7T3S1_XENLA ---MPTTTVLKPVLK---MKVDELFLRWLSETPTQLLLNDYLRRIKNGEKI-LPETDDYG Q4RWF0_TETNG Q4RWF0_TETNG ------------------------------------------------------------ A7Y4D1_CARAU A7Y4D1_CARAU ---MASPQTLQPVLK---MKVDELFLFWLSEPSTQAMLKVYLDKIKNGEEIELSHADFKG B0S5T5_DANRE B0S5T5_DANRE --MRMKEISLRQDPD---LRKELALLARGCDFVLPSRFKKRLKAFQQGQQA--------- A4QN80_DANRE A4QN80_DANRE ------------------------------------------------------------ B0S5T6_DANRE B0S5T6_DANRE ---MASPQTLQPVLK---MKVDELFLFWLSEPSTQAMLKDYLNKIKSGEEIDLSHGEFKG MATCH CONSENSUS ????????????????????????????????????????????????????????????

B1WBU2_RAT B1WBU2_RAT PATA-----------LDSATKAIAAPAKIAPPDP-AVTPNPAAIASSTAITKFSASRKRN P2R3A_MOUSE P2R3A_MOUSE --------------------VHAHRKEEPPPQSP-------------------------- Q8K1A4_MOUSE Q8K1A4_MOUSE --------------------PGTTSDPAAAATPDADPGNTTSDPNPASRPLPRPALRTTG A6QNV9_BOVIN A6QNV9_BOVIN --------------------TQIQNKPEKKPGTPLPPPAPFPSSPRPPSPVPHVNNVVSA B4DNU1_HUMAN B4DNU1_HUMAN ------------------------------------------------------------ B4DS28_HUMAN B4DS28_HUMAN --------------------TQIQNKPEKKPGTPLPPPATSPSSPRPLSPVPHVNNVVNA Q5PQN8_RAT Q5PQN8_RAT --------------------TQIQNKPEKKPATPCPPAATLPSSPQPASPVPCVSDVVNT Q3V1Y6_MOUSE Q3V1Y6_MOUSE --------------------TQIQNKPEKKPATSFPPAATLPSSPQPASPVPCVSDVVNT Q8BM38_MOUSE Q8BM38_MOUSE --------------------TQIQNKPEKKPATSFPPAATLPSSPQPASPVPCVSDVVNT A1L2R4_XENLA A1L2R4_XENLA --------------------AQIQSKQEKKPSTP-PPAPLTPTVSPRPATPPLPSSKVTA A7UNT4_CARAU A7UNT4_CARAU ------------------------------------------------------------ B0S5Q0_DANRE B0S5Q0_DANRE ----------------------AQIQPEKKPGTP-PPTLSPAPSSPTPRPPSPPPAKVVA P2R3B_HUMAN P2R3B_HUMAN PGAW-----------PTAPLAAPRPSGLEPPGTPGPGPALPLGAASSPRNAPHVRGTRRS Q96FD8_HUMAN Q96FD8_HUMAN ------------------------------------------------------------ Q9UHL2_HUMAN Q9UHL2_HUMAN ------------------------------------------------------------ Q498G0_XENLA Q498G0_XENLA ------------------------------------------------------------ Q08D09_XENTR Q08D09_XENTR TKEI-----------PSKSTLHSAHKALDNLSLS-PQSALPPGSYGSPRSGLTPRKRRSS A1A5J1_XENLA A1A5J1_XENLA TKEI-----------SSKSTLHSVHKALDNLSLS-PQSALPPGSYGSPRSGLTPRKRRSS Q7T3S1_XENLA Q7T3S1_XENLA TKEI-----------SSKSTLHSVHKALDNLSLS-PQSALPPGSYGSPMSGLTPRKRRSS Q4RWF0_TETNG Q4RWF0_TETNG ------------------------------------------------------------ A7Y4D1_CARAU A7Y4D1_CARAU TSTLLLAENNNNNIASKINATERMTAALGAPCSP-PSATLPSASGSNNRAGVNARALRRS B0S5T5_DANRE B0S5T5_DANRE ------------------------------------------------------------ A4QN80_DANRE A4QN80_DANRE ------------------------------------------------------------ B0S5T6_DANRE B0S5T6_DANRE TSTLMFTENNNNNIASKINATERMSAALGAPCSP-PSATLPSATGSNNRAGVNARALRRS MATCH CONSENSUS ????????????????????????????????????????????????????????????

B1WBU2_RAT B1WBU2_RAT RHRAVPPRGEEPGPKAPLPGRGIPAFYFPRGRPGQGP-DVDDVIADVERAFARLPSGRAG P2R3A_MOUSE P2R3A_MOUSE -----------------PPGHTVPAFYFPCGRPPPRPQDTEDAIALVECAFEGLPRGRAG Q8K1A4_MOUSE Q8K1A4_MOUSE PRTVHAHRKEEPPPQSPPPGHSVPAFYFPCGRPPPRPQDTEDAIALVECAFEGLPRGRAG A6QNV9_BOVIN A6QNV9_BOVIN -----------------TLSINIPRFYFPEGLPDACS-NHEQTLSRIEAAFMDIEDQKAD B4DNU1_HUMAN B4DNU1_HUMAN ---------------------------------------------------MDIEEQKAD B4DS28_HUMAN B4DS28_HUMAN -----------------PLSINIPRFYFPEGLPDTCS-NHEQTLSRIETAFMDIEEQKAD Q5PQN8_RAT Q5PQN8_RAT -----------------PLSINIPQFYFPEGLPDTCS-NHEQILGRIEAAFKDIEDQKAD Q3V1Y6_MOUSE Q3V1Y6_MOUSE -----------------PLSINIPQFYFPEGLPDTCS-NHEQILSRIETAFKDIEDQKAD Q8BM38_MOUSE Q8BM38_MOUSE -----------------PLSINIPQFYFPEGLPDTCS-NHEQILSRIETAFKDIEDQKAD A1L2R4_XENLA A1L2R4_XENLA -----------------PVSINIPRFYFPKGLPNPGS-DYEDSIKKTEAAFSSMAEEKAD A7UNT4_CARAU A7UNT4_CARAU -----------------------------KGLPNCAA-NYDEAIAKIEAAFTEFEEEKAD B0S5Q0_DANRE B0S5Q0_DANRE --------------TPPPSSINIPRFYFPKGLPNCAA-NYDEAIAKIEAAFTEFEEEKAD P2R3B_HUMAN P2R3B_HUMAN -AGTRVVQTRKEEPLPPATSQSIPTFYFPRGRPQDSV-NVDAVISKIESTFARFPHERAT Q96FD8_HUMAN Q96FD8_HUMAN ------------------------------------------------------------ Q9UHL2_HUMAN Q9UHL2_HUMAN ------------------------------------------------------------ Q498G0_XENLA Q498G0_XENLA -----------------------------------NF-NIDGIIARIEKTFSGFPLERAT Q08D09_XENTR Q08D09_XENTR --SVGVVHPKKEEPLTPALSQNIPKFYFPKGCPKANL-NIDGIISKIEKTFSGFPLERAT A1A5J1_XENLA A1A5J1_XENLA --SVGVVHPKKEEPLTPALSQNIPKFYFPKGCPKTNF-NIDGIISKIEKTFSDFPLERAT Q7T3S1_XENLA Q7T3S1_XENLA --SVGVVHPKKEEPLTPALSQNIPKFYFPKGCPKTNF-NIDGIISKIEKTFSDFPLERAT Q4RWF0_TETNG Q4RWF0_TETNG ------------------------------------------------------------ A7Y4D1_CARAU A7Y4D1_CARAU VSTKKQAQAKKEEPVTPALSESIPKFYFPRGQPQANI-NIDNLISKIEKIFSQFPDERVT B0S5T5_DANRE B0S5T5_DANRE -------QAKKEEPVTPALSESIPKFYFPRGQPQANI-NIDNLISKIEKIFSQFPDERVT A4QN80_DANRE A4QN80_DANRE -------------------SESIPKFYFPRGQPQANI-NIDNLISKIEKIFSQFPDERVT B0S5T6_DANRE B0S5T6_DANRE VSTKKQAQAKKEEPVTPALSESIPKFYFPRGQPQANI-NIDNLISKIEKIFSQFPDERVT MATCH CONSENSUS ???????????????????????????????????????????????E??F?????????

B1WBU2_RAT B1WBU2_RAT LQDMGVVAKACCCPLYWKAPLFLAAGGGAQGGFVSARDIIGLWKPILLTCHDEAARFERL P2R3A_MOUSE P2R3A_MOUSE LGDMAVVAKACGCPLYWKAPLFYAA-GGERTGSVSVHMFVAMWRKVLLTCHDDAARFVRL Q8K1A4_MOUSE Q8K1A4_MOUSE LGDMAVVAKACGCPLYWKAPLFYAA-GGERTGSVSVHMFVAMWRKVLLTCHDDAARFVRL A6QNV9_BOVIN A6QNV9_BOVIN VYEMGKIAKACGCPLYWKAPMFRAA-GGERTGFVSAQSFITIWRKLLSNHHDDASKFICL B4DNU1_HUMAN B4DNU1_HUMAN IYEMGKIAKVCGCPLYWKAPMFRAA-GGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICL B4DS28_HUMAN B4DS28_HUMAN IYEMGKIAKVCGCPLYWKAPMFRAA-GGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICL Q5PQN8_RAT Q5PQN8_RAT IHEMGRIAKACGCPLYWKAPMFRAA-GGEKTGFVTAQSFMAMWKKLLSDHHDDASRFIWL Q3V1Y6_MOUSE Q3V1Y6_MOUSE IHEMGRIAKVCGCPLYWKAPMFRAA-GGEKTGFVTAQSFIAMWKKLLSNRHDDAAKFIWL Q8BM38_MOUSE Q8BM38_MOUSE IHEMGRIAKVCGCPLYWKAPMFRAA-GGEKTGFVTAQSFIAMWKKLLSNRHDDAAKFIWL A1L2R4_XENLA A1L2R4_XENLA IYQMGKIAKVCGCPLYWKAALFNAA-GGERTGFVSVHSFIAMWRKLIQNCHDDASKFVSL A7UNT4_CARAU A7UNT4_CARAU IYEMGKIAKACGCPLYWKAPMFICA-GGERTGFVSVHSFIATWRKLLHSCYDDASKFVYL B0S5Q0_DANRE B0S5Q0_DANRE IYEMGKIAKACGCPLYWKSPMFICA-GGERTGFVSVHSFIATWRKLLHSCYDDASKFVYL P2R3B_HUMAN P2R3B_HUMAN MDDMGLVAKACGCPLYWKGPLFYGA-GGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHL Q96FD8_HUMAN Q96FD8_HUMAN ------------------------------------------------------------ Q9UHL2_HUMAN Q9UHL2_HUMAN ------------------------------------------------------------ Q498G0_XENLA Q498G0_XENLA LEDMGKVAKACECPLYWKAPLFYAA-GGDRTGYISVHKFIAMWRKILQTCHDDSAKFMQL Q08D09_XENTR Q08D09_XENTR LEDMGKVAKACECPLYWKAPLFYAA-GGERTGYVSVHKFIAMWRKILHTCHDDAAKFMQL A1A5J1_XENLA A1A5J1_XENLA LEDMGKVAKACECPMYWKAPLFYAA-GGERTGYVSVHKFIAVWRKILQTCHDDSAKFMQL Q7T3S1_XENLA Q7T3S1_XENLA LEDMGKVAKACECPMYWKAPLFYAA-GGERTGYVSVHKFIAVWRKILQTCHDDSAKFMQL Q4RWF0_TETNG Q4RWF0_TETNG --------QACECSLYWKMPLFCLA-GGDRTGFVSVHKFVAVWRKTLQTCHDDASKFVHL A7Y4D1_CARAU A7Y4D1_CARAU LKDMGLVAKACECPLYWKAPLFHAA-GGDRRGYVSVHKFVAMWRKVLQTCHDDASKFLHL B0S5T5_DANRE B0S5T5_DANRE IKDMGLVAKACDCPFYWKAPLFHAA-GGDRRGYVSVHKFVAMWRKVLQTCHDDASKFLHL A4QN80_DANRE A4QN80_DANRE IKDMGLVAKACDCPFYWKAPLFHAA-GGDRRGYVSVHKFVAMWRKVLQTCHDDASKFLHL B0S5T6_DANRE B0S5T6_DANRE IKDMGLVAKACDCPFYWKAPLFHAA-GGDRRGYVSVHKFVAMWRKVLQTCHDDASKFLHL MATCH CONSENSUS ???M???AK?C?CP?YWK?P?F??A?GG???G?V????F?A?W?K?L???HDD???F??L

B1WBU2_RAT B1WBU2_RAT LGGPGDGGLSPEDLAPLVQDVADSHPGLSFLREAEPLRRDYVTTVTQRVFYAVNRSWSGR P2R3A_MOUSE P2R3A_MOUSE LGHPGCSGLIQEDFVPFLQDVVNSHPGLAFLRAAKDFHSRYITTVIQRIFYTVNRSWSGM Q8K1A4_MOUSE Q8K1A4_MOUSE LGHPGCSGLIQEDFVPFLQDVVNSHPGLAFLRAAKDFHSRYITTVIQRIFYTVNRSWSGM A6QNV9_BOVIN A6QNV9_BOVIN LAKPSCSSLEQDDFIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGK B4DNU1_HUMAN B4DNU1_HUMAN LAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGK B4DS28_HUMAN B4DS28_HUMAN LAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGK Q5PQN8_RAT Q5PQN8_RAT LAKPSCSHLQQEDFIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVVQRIFYTVNRSWSGK Q3V1Y6_MOUSE Q3V1Y6_MOUSE LAKPSCSYLEQEDFIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVVQRIFYTVNRSWSGK Q8BM38_MOUSE Q8BM38_MOUSE LAKPSCSYLEQEDFIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVVQRIFYTVNRSWSGK A1L2R4_XENLA A1L2R4_XENLA LAKPGCDYLEQEDFIPLLQDIVDTHPGLTFLKEAPEFHSRYITTVIQRIFYTVNRSWSGR A7UNT4_CARAU A7UNT4_CARAU LAKPGCNYLEQEDFIPLLQDIVDTHSGLTFLKDAPEFHSRYPTTVIQRIFYTVNRSWTGK B0S5Q0_DANRE B0S5Q0_DANRE LAKPGCTYLEQEDFIPLLQDIVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWTGK P2R3B_HUMAN P2R3B_HUMAN LMSPGCNYLVQEDFVPFLQDVVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGR Q96FD8_HUMAN Q96FD8_HUMAN ------------------------------------------------------------ Q9UHL2_HUMAN Q9UHL2_HUMAN ------------------------------------------------------------ Q498G0_XENLA Q498G0_XENLA LAKPGCNYLEQEDFIPFLQDVVNTHPHLTFLREASEFHSRYITTVVQRIFYQVNRSWSGR Q08D09_XENTR Q08D09_XENTR LAKPGCSYLEQEDFIPFLQDVVNTHPHLTFLREASEFHSRYITTVVQRIFYLVNRSWSGR A1A5J1_XENLA A1A5J1_XENLA LAKPGCNYLEQEDFIPFLQDVVNTHPHLTFLSEASEFHSRYITTVVQRIFYQVNRSWSGR Q7T3S1_XENLA Q7T3S1_XENLA LAKPGCNYLEQEDFIPFLQDVVNTHPHLTFLSEASEFHSRYITTVVQRIFYQVNRSWSGR Q4RWF0_TETNG Q4RWF0_TETNG LAKPGCNYLEQDDFIPFLQDVVNSHPGLAFLKEAPDFHSRYITTVIQRIFYNVNRSWSGK A7Y4D1_CARAU A7Y4D1_CARAU LAKPGCNYLEQEDFIPFLQDVVDSHTGLAFLKEASDFHSRYITTVVQRIFYNVNRSWTGK B0S5T5_DANRE B0S5T5_DANRE LAKPGCNYLEQEDFIPFLQDVVDSHTGLAFLKEASDFHSRYITTVVQRIFYNVNRSWTGK A4QN80_DANRE A4QN80_DANRE LAKPGCNYLEQEDFIPFLQDVVDSHTGLAFLKEASDSHSRYITTVVQRIFYNVNRSWTGK B0S5T6_DANRE B0S5T6_DANRE LAKPGCNYLEQEDFIPFLQDVVDSHTGLAFLKEASDFHSRYITTVVQRIFYNVNRSWTGK MATCH CONSENSUS L??P?C??L?QEDF?P?LQD?V??H??L?FL??A??FHSRYITTV?QRIFY?VNRSW?G?

B1WBU2_RAT B1WBU2_RAT ISCQEIRRSCFLQAVSQLEAEPNPGRATPSFFSYPHFCVIVSKFQALDADGDGLIDRHDL P2R3A_MOUSE P2R3A_MOUSE ISREELRRSSFLQAVSQLEVEPDINRMT-SFFSYEHFYVIYCKFWELDLDRDLTIDRSDL Q8K1A4_MOUSE Q8K1A4_MOUSE ISREELRRSSFLQAVSQLEVEPDINRMT-SFFSYEHFYVIYCKFWELDLDRDLTIDRSDL A6QNV9_BOVIN A6QNV9_BOVIN ITATEIRKSNFLQTLALLEEEEDINQIT-DYFSYEHFYVIYCKFWELDSDHDLYISQADL B4DNU1_HUMAN B4DNU1_HUMAN ITSTEIRKSNFLQTLALLEEEEDINQIT-DYFSYEHFYVIYCKFWELDTDHDLYISQADL B4DS28_HUMAN B4DS28_HUMAN ITSAEIRKSNFLQTLALLEEEEDINQIT-DYFSYEHFYVIYCKFWELDTDHDLYISQADL Q5PQN8_RAT Q5PQN8_RAT ITSTEIRKSNFLQTLALLEEEEDINQIT-DYFSYEHFYVIYCKFWELDGDHDLYISQADL Q3V1Y6_MOUSE Q3V1Y6_MOUSE ITSTEIRKSNFLQTLALLEEEEDINQIT-DYFSYEHFYVIYCKFWELDGDHDLYISQADL Q8BM38_MOUSE Q8BM38_MOUSE ITSTEIRKSNFLQTLALLEEEEDINQIT-DYFSYEHFYVIYCKFWELDGDHDLYISQADL A1L2R4_XENLA A1L2R4_XENLA ITLIEMKRSNFLQTLALLEEEDDINQVT-DYFSYEHFYVIYCKFWELDTDHDLYIDHKDL A7UNT4_CARAU A7UNT4_CARAU INMTELRRSNFLQTLALLEEEDDINQIT-DYFSYEHFYVIYCKFWELDADHDLFIDPKDL B0S5Q0_DANRE B0S5Q0_DANRE INMTELRRSNFLQTLALLEEEDDINQIT-DYFSYEHFYVIYCKFWELDSDHDLFIDPKDL P2R3B_HUMAN P2R3B_HUMAN ITCAELRRSSFLQNVALLEEEADINQLT-EFFSYEHFYVIYCKFWELDTDHDLLIDADDL Q96FD8_HUMAN Q96FD8_HUMAN -----------------------------------------CKFWELDTDHDLLIDADDL Q9UHL2_HUMAN Q9UHL2_HUMAN ------------------------------------------KFWELDTDHDLLIDADDL Q498G0_XENLA Q498G0_XENLA ITCSELRKSNFLQHVALLEEE-DINQSS-DYFSYEHFYVIYCKFWELDTDHDLYIDENDL Q08D09_XENTR Q08D09_XENTR ITCSELRKSNFLQHVALLEEE-DINQSA-DYFSYEHFYVIYCKFWELDTDHDLYIDENDL A1A5J1_XENLA A1A5J1_XENLA ITCSELRKSNFLQHVALLEEE-DINQSA-DYFSYEHFYVIYCKFWELDSDHDLYIDESDL Q7T3S1_XENLA Q7T3S1_XENLA ITCSELRKSNFLQHVALLEEE-DINQSA-DYFSYEHFYVIYCKFWELDSDHDLYIDESDL Q4RWF0_TETNG Q4RWF0_TETNG ITCSELRKSNFLQNVALLEQEEDVNQLT-EFFSYEHFYVIYCKFWELDTDHDLYIDQRDL A7Y4D1_CARAU A7Y4D1_CARAU ITCSELRRSSFLQNVALLEEEEEINQLT-EFFSYEHFYVIYCKFWELDTDHDLYIDQRDL B0S5T5_DANRE B0S5T5_DANRE ITCSELRRSTFLQNVALLEEDEEINQLT-EFFSYEHFYVIYCKFWELDTDHDLYIDQRDL A4QN80_DANRE A4QN80_DANRE ITCSELRRSTFLQNVALLEEDEEINQLT-EFFSYEHFYVIYCKFWELDTDHDLYIDQRDL B0S5T6_DANRE B0S5T6_DANRE ITCSELRRSTFLQNVALLEEDEEINQLT-EFFSYEHFYVIYCKFWELDTDHDLYIDQRDL MATCH ** ** * * *. ** CONSENSUS I???E?R?S?FLQ????LE????IN??????FSYEHFYVIYCKFWELD?DHDL?I???DL

B1WBU2_RAT B1WBU2_RAT RRHADGAISSRMIDRIFSGAVTRARPSPEGGKMGLADFVWFLLSEEDKTTPTSTEYWFRC P2R3A_MOUSE P2R3A_MOUSE ARHGDGAISSRMIDRIFSGAVTRARLPRKVGKLSYADFVWFLLSEEDKTTPTSTEYWFRC Q8K1A4_MOUSE Q8K1A4_MOUSE ARHGDGAISSRMIDRIFSGAVTRARLPRKVGKLSYADFVWFLLSEEDKTTPTSTEYWFRC A6QNV9_BOVIN A6QNV9_BOVIN SRYNDQASSNRIIERIFSGAVTRGKTVQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRC B4DNU1_HUMAN B4DNU1_HUMAN SRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRC B4DS28_HUMAN B4DS28_HUMAN SRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRC Q5PQN8_RAT Q5PQN8_RAT SRYNDQASSNRIIERIFSGAVTRGKTVQREGRMSYADFVWFLISEEDKRNPTSIEYWFRC Q3V1Y6_MOUSE Q3V1Y6_MOUSE SRYNDQASSNRIIERIFSGAVTRGKTVQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRC Q8BM38_MOUSE Q8BM38_MOUSE SRYNDQASSNRIIERIFSGAVTRGKTVQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRC A1L2R4_XENLA A1L2R4_XENLA ARYNDHASSKRIIERIFSGAVTRGNAVQREGRMSYAEFVWFLISEEDKKNPTSMEYWFRC A7UNT4_CARAU A7UNT4_CARAU ARYNDHASSSRVIERLFSGAVTRGNSVQREGRMSYAEFVWFLISEEDKKNPTSAEYWFRC B0S5Q0_DANRE B0S5Q0_DANRE ARYNDHASSSRIIERLFSGAVTRGNSVQREGRMSYAEFVWFLISEEDKKNPTSIEYWFRC P2R3B_HUMAN P2R3B_HUMAN ARHNDHALSTKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRC Q96FD8_HUMAN Q96FD8_HUMAN ARHNDHALSTKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRC Q9UHL2_HUMAN Q9UHL2_HUMAN ARHNDHALSTKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRC Q498G0_XENLA Q498G0_XENLA AKHNDNAISSHVIQRIFSGAVTRSRKIHKEGKISYADFVWFLLSEEDKKTHASIEYWFRC Q08D09_XENTR Q08D09_XENTR AKHNDHAISSHVIQRIFSGTVTRSRKVHKEGKISYADFVWFLLSEEDKKTQTSIEYWFRC A1A5J1_XENLA A1A5J1_XENLA AKHNDHAISSHVIQRIFSGAVTRNRKVHKEGKISYADFVWFLLSEEDKKTQTSIEYWFRC Q7T3S1_XENLA Q7T3S1_XENLA AKHNDHAISSHVIQRIFSGAVTRNRKVHKEGKISYTDFVWFLLSEEDKKTQTSIEYWFRC Q4RWF0_TETNG Q4RWF0_TETNG AQHNDQAISHKMIERIFSGTVTRDRRVYKEGRLSYADFVWFLISEEDKKTDTSVEYWFRC A7Y4D1_CARAU A7Y4D1_CARAU MRHNDQAISHRMTERLFSGAVTRDRKVHKEGRLSYADFVWFLISEEDKKTETSIEYWFRC B0S5T5_DANRE B0S5T5_DANRE MRHNDQAISHRMIERIFSGAVTRGRAVHKEGRLSYGDFVWFLISEEDKKTETSIEYWFRC A4QN80_DANRE A4QN80_DANRE MRHNDQAISHRMIERIFSGAVTRGRAVHKEGRLSYGDFVWFLISEEDKKTETSIEYWFRC B0S5T6_DANRE B0S5T6_DANRE MRHNDQAISHRMIERIFSGAVTRGRAVHKEGRLSYGDFVWFLISEEDKKTETSIEYWFRC MATCH :: * * * :: :*:***:*** . . *::. :*****:***** . :* ****** CONSENSUS ???ND?A?S???I?RIFSGAVTR??????EG??SYADFVWFL?SEEDK???TS?EYWFRC

B1WBU2_RAT B1WBU2_RAT MDLDGDGVLSAPELSFFYEEQAQNLAARGAEPPPFADLTRQALDLVQPRCPGQITLGDLK P2R3A_MOUSE P2R3A_MOUSE MDLDGDGALSMFELEFFYEEQAQRMAARGVEPLPFHDLARQVLDLVAPRCPGRITLRDLK Q8K1A4_MOUSE Q8K1A4_MOUSE MDLDGDGALSMFELEFFYEEQAQRMAARGVEPLPFHDLARQVLDLVAPRCPGRITLRDLK A6QNV9_BOVIN A6QNV9_BOVIN MDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPASDGKITLRDLK B4DNU1_HUMAN B4DNU1_HUMAN MDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLK B4DS28_HUMAN B4DS28_HUMAN MDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLK Q5PQN8_RAT Q5PQN8_RAT MDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPANDGRITLRDLK Q3V1Y6_MOUSE Q3V1Y6_MOUSE MDVDGDGILSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPASDGRITLRDLK Q8BM38_MOUSE Q8BM38_MOUSE MDVDGDGILSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPASDGRITLRDLK A1L2R4_XENLA A1L2R4_XENLA MDLDGDGVLSMYELEFFYEEQCEKMEAMGIEPLPFQDLLCQLLDLVKPEAEGQITLRDLK A7UNT4_CARAU A7UNT4_CARAU MDMDGDGVLSMFELEFFYEEQCERMEGMGIEPLPFQDLLCQMLDLVKPECPGKITLRDLK B0S5Q0_DANRE B0S5Q0_DANRE MDMDGDGVLSMFELEYLYEEQCERMEGMGIEPLPFQDLLCQMLDLVKPECPSKITLRDLK P2R3B_HUMAN P2R3B_HUMAN MDLDGDGALSMFELEYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLK Q96FD8_HUMAN Q96FD8_HUMAN MDLDGDGALSMFELEYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLK Q9UHL2_HUMAN Q9UHL2_HUMAN MDLDGDGALSMFELEYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLK Q498G0_XENLA Q498G0_XENLA MDLDGDGVLSMYELEYFYEEQCQKMESLAIEPLPFEDCLCQMLDLVKPQTEGKITLHDLK Q08D09_XENTR Q08D09_XENTR MDLDGDGVLSMYELEYFYEEQCQKMESMAIEPLPFEDCLCQMLDLVKPQTEGKITLHDLK A1A5J1_XENLA A1A5J1_XENLA MDLDGDGVLSMYELEYFYEEQCQKMESMAIEPLPFEDCLCQMLDLVKPQTEGKITLHDLK Q7T3S1_XENLA Q7T3S1_XENLA MDLDGDGVLSKYELEYFYEEQCQKMESMPIGALAFWRIAFADVGLVKPQTEGKITLHDLK Q4RWF0_TETNG Q4RWF0_TETNG MDLDGDGVLSMYELEFFYEEQCQKLEAMAIEPLPFEDCLCQMLDLVKPEVEGKISLRDLK A7Y4D1_CARAU A7Y4D1_CARAU MDLDGDGVLSMYELEYFYQEQSQKLEALAIEPLPFEDCLCQMLDMVKPEIPGKISLRDLK B0S5T5_DANRE B0S5T5_DANRE MDLDGDGVLSMYELQYFYQEQCQKLEAMAIEPLPFEDCLCQMLDLVKPENPGKITLRDLK A4QN80_DANRE A4QN80_DANRE MDLDGDGVLSMYELQYFYQEQCQKLEAMAIEPLPFEDCLCQMLDLVKPENPGKITLRDLK B0S5T6_DANRE B0S5T6_DANRE MDLDGDGVLSMYELQYFYQEQCQKLEAMAIEPLPFEDCLCQMLDLVKPENPGKITLRDLK MATCH **:**** ** **.::*:**...: . . .* :.:* * .:*:* *** CONSENSUS MD?DGDG?LSM?ELE?FYEEQC???????IEPLPF?D?LCQ?LDLVKP???G?ITL?DLK

B1WBU2_RAT B1WBU2_RAT RCGLAGEFFDAFFNADKFLEHERREPAGPVRAPDAD-PTLSDWDRFAAAEYDFLLAEEAQ P2R3A_MOUSE P2R3A_MOUSE QCGLAGEFFDAFFNVDKYLAREQREQAGTPQDTDSD-PAASAWDRYAAEEYDFLVAEEAM Q8K1A4_MOUSE Q8K1A4_MOUSE QCGLAGEFFDAFFNVDKYLAREQREQAGTPQDTDSD-PAASAWDRYAAEEYDFLVAEEAM A6QNV9_BOVIN A6QNV9_BOVIN RCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDSPEPSDWDRFAAEEYETLVAEESA B4DNU1_HUMAN B4DNU1_HUMAN RCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESA B4DS28_HUMAN B4DS28_HUMAN RCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESA Q5PQN8_RAT Q5PQN8_RAT RCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENEGPEPSDWDRFAAEEYEALVTEESA Q3V1Y6_MOUSE Q3V1Y6_MOUSE RCRMAQIFYDTFFNLEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYEALVTEESA Q8BM38_MOUSE Q8BM38_MOUSE RCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYEALVTEESA A1L2R4_XENLA A1L2R4_XENLA RCKMAHIFYDTCFNLEKYLDHEQRDPFAVQKDIESENPEPSDWDRYAAEEYEILVAEESA A7UNT4_CARAU A7UNT4_CARAU RCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDLDSDGPEPSDWDKYAAEEYEILVAEETA B0S5Q0_DANRE B0S5Q0_DANRE RCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDLDSDGPEPSDWDKYASEEYEILVAEETA P2R3B_HUMAN P2R3B_HUMAN RCKLANVFFDTFFNIEKYLDHEQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETA Q96FD8_HUMAN Q96FD8_HUMAN RCKLANVFFDTFFNIEKYLDHEQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETA Q9UHL2_HUMAN Q9UHL2_HUMAN RCKLANVFFDTFFNIEKYLDHEQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETV Q498G0_XENLA Q498G0_XENLA KCKQANIFFDTFLNLEKYLDQEQKDPFSVLRVGENEGQELSDWEKYAAEEYAVLVAEEAA Q08D09_XENTR Q08D09_XENTR KCKQANIFFDTFLNLEKYLDHEQKDPFSVLRVGENEGQELSDWEKYAAEEYAVLVAEEAA A1A5J1_XENLA A1A5J1_XENLA KCKQANIFLDTFLNLEKYLDHEQKDPFSVLRVGENEGQELSDWEKYAAEEYAVLVAEEAA Q7T3S1_XENLA Q7T3S1_XENLA KCKQANIFLDTFLNLEKYLDHEQKDPFSVLRVGENEGQELSDWEKYAAEEYAVLVAEEAA Q4RWF0_TETNG Q4RWF0_TETNG RCKLSHIFFDTFFNIEKYLEHEQKDPFSVIRELEAEGQEVSDWEKYAAEEYDILVAEEAA A7Y4D1_CARAU A7Y4D1_CARAU RCKLSHIFFDTFFNVERYLDHEQSDPLLAARDAETVGQEISDWERYAAEEYDNLVAEETA B0S5T5_DANRE B0S5T5_DANRE RCRMSHIFFDTFFNIEKYLDHEQRDPLLAARDAEAVGQEISDWERYAAEEYDNLVAEETA A4QN80_DANRE A4QN80_DANRE RCRMSHIFFDTFFNIEKYLDHEQRDPLLAARDAEAVGQEISDWERYAAEEYDNLVAEETA B0S5T6_DANRE B0S5T6_DANRE RCRMSHIFFDTFFNIEKYLDHEQRDPLLAARDAEAVGQEISDWERYAAEEYDNLVAEETA MATCH :* : * *: :* :::* :*: : : : * *:::*: ** *::**: CONSENSUS ?C?????F?DTFFN?EKYLDHEQ???????????????E?SDW???AAEEY??LVAEE?A

B1WBU2_RAT B1WBU2_RAT DDDAWEEG------------------------------SESPPSSPDPYDFADDTLDPL P2R3A_MOUSE P2R3A_MOUSE AED--DDD-HDEGSDPID---------------LYGLADEDC-----------DDLEPL Q8K1A4_MOUSE Q8K1A4_MOUSE AED--DDD-HDEGSDPID---------------LYGLADEDC-----------DDLEPL A6QNV9_BOVIN A6QNV9_BOVIN QAQ-FQEG-SFEDYETEEPPSPSEIGNKGNKIVTSSLSEKCGKLQSVDEE--------- B4DNU1_HUMAN B4DNU1_HUMAN QAQ-FQEG-F-EDYETDEPASPSEFGNKSNKILSASLPEKCGKLQSVDEE--------- B4DS28_HUMAN B4DS28_HUMAN QAQ-FQEG-F-EDYETDEPASPSEFGNKSNKILSASLPEKCGKLQSVDEE--------- Q5PQN8_RAT Q5PQN8_RAT QVQ-LQEG-SFEDYESDEPVSPSELGNKGNKILTSSLSEKCGKLQSVDEE--------- Q3V1Y6_MOUSE Q3V1Y6_MOUSE QVQ-LQEG-SFEDYESDEPVSPSELGNKGNKIVTSSLSEKCGKLQSVDEE--------- Q8BM38_MOUSE Q8BM38_MOUSE QVQ-LQEG--------------------------------------------------- A1L2R4_XENLA A1L2R4_XENLA TEQ-LQEGSFDDDYEGEEVLSPPEISNEVDKLVISDLTA-------------------- A7UNT4_CARAU A7UNT4_CARAU NEQ-LREGSFDDDYESDELTVSTDIGNKMNKLVISDLSG-------------------- B0S5Q0_DANRE B0S5Q0_DANRE NEQ-LREGSFDDDYESDELTVSSDIGNKMDKLVISDLSA-------------------- P2R3B_HUMAN P2R3B_HUMAN GEP-WEDG-FEAELSPVEQKLSALR-SPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL Q96FD8_HUMAN Q96FD8_HUMAN GEP-WEDG-FEAELSPVEQKLSALR-SPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL Q9UHL2_HUMAN Q9UHL2_HUMAN GEP-WEDG-FEAELSPVEQKLSALR-SPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL Q498G0_XENLA Q498G0_XENLA NEQ-WNDG-YDGELNILDIPVANKDKCSADKRSFFELPSHSSEVDLEEYEY-EDDFE-- Q08D09_XENTR Q08D09_XENTR NEQ-WNDG-YDAELNLLDIPVASEDKCSSDKRPFFDLPSHSPEADLEEYEY-EDDFE-- A1A5J1_XENLA A1A5J1_XENLA NEQ-WNDG-YDAELNLLDVPVA----NADDKRPFFELPSHSSEVDLEEYEY-EDDFE-- Q7T3S1_XENLA Q7T3S1_XENLA NEQ-WNDG-YDAELNLLDVPVA----NADDKRPFFELPSHSSEVDLEEYEY-EDDFE-- Q4RWF0_TETNG Q4RWF0_TETNG NED-CNDV-YENHLSPL--PTQANSSELGLKRHFFDFPSIGCNLNLDEYDC-QEDFE-- A7Y4D1_CARAU A7Y4D1_CARAU NEP-YNDC-YDNVLHPIDHITCAFD-LGNEKRPLFEIPNPHC--DLDEYEY-VDDFE-- B0S5T5_DANRE B0S5T5_DANRE NEQ-YHDG--------------------------------------------------- A4QN80_DANRE A4QN80_DANRE NEQ-YHDG-YDNILDPADHVTSALE-LHSEKRHLFGIPSPHCNLDLDEYEY-EDDFE-- B0S5T6_DANRE B0S5T6_DANRE NEQ-YHDG-YDNILDPADHVTSALE-LHSEKRHLFGIPSPHCNLDLDEYEY-EDDFE-- MATCH : CONSENSUS ???????G???????????????????????????????????????????????????


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