Alignment of the gene Family HBG000053 of HOVERGEN

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Isoforms are OFF
Q8VDV4_MOUSE Q8VDV4_MOUSE ------------------------------------------------------------ Q9NWG2_HUMAN Q9NWG2_HUMAN ---------------------------------------------------------MTG B8JMJ3_DANRE B8JMJ3_DANRE ------------------------------------------------------------ Q502G3_DANRE Q502G3_DANRE -------------------------------------------------MEAEAEAPELN Q4T3X4_TETNG Q4T3X4_TETNG ELSEAERVVELGLVQAEAGEARQLWECVWGTLQVRMESRGRALAPPIPEEGEAPGGVLHR B5X112_SALSA B5X112_SALSA ---------------------------------------------------------MLG Q4SHX2_TETNG Q4SHX2_TETNG ------------------------------------------------------------ Q501W5_DANRE Q501W5_DANRE ---------------------------------------------------------MLG Q9D7B2_MOUSE Q9D7B2_MOUSE ---------------------------------MAFPGRARPCTIPENEEIPQTALNSVL B4F6Z9_XENTR B4F6Z9_XENTR ----------------------------------------------------------MS Q6GMB2_XENLA Q6GMB2_XENLA ---------------------------------------------------------MLG A7LBJ1_XENLA A7LBJ1_XENLA ---------------------------------------------------------MLG Q6INR9_XENLA Q6INR9_XENLA ---------------------------------------------------------MLG Q5ZL81_CHICK Q5ZL81_CHICK ---------------------------------------------------------MLG Q6IYF7_CHICK Q6IYF7_CHICK ------------------------------------------------------------ A4FV50_BOVIN A4FV50_BOVIN ---------------------------------------------------------MLG B7Z483_HUMAN B7Z483_HUMAN ---------------------------------------------------------MLG B7Z7R3_HUMAN B7Z7R3_HUMAN ---------------------------------MAFSGRARPCIIPENEEIPRAALNTVH B7Z907_HUMAN B7Z907_HUMAN ---------------------------------------------------------MTA LIMS1_HUMAN LIMS1_HUMAN ------------------------------------------------------------ A8CVP1_MOUSE A8CVP1_MOUSE --------------------------------------------------------MTTL Q4ZJB3_MOUSE Q4ZJB3_MOUSE ---------------------------------MAFPGRARPCTIPENEEIPQTALNSVL LIMS1_MOUSE LIMS1_MOUSE ------------------------------------------------------------ A8CVP4_MOUSE A8CVP4_MOUSE ------------------------------------------------------------ Q5PQM7_RAT Q5PQM7_RAT ------------------------------------------------------------ LIMS2_MOUSE LIMS2_MOUSE ---------------------------------------------------------MTG LIMS2_BOVIN LIMS2_BOVIN ---------------------------------------------------------MTG B3KNZ3_HUMAN B3KNZ3_HUMAN ------------------------------------------------------------ B4DMV1_HUMAN B4DMV1_HUMAN ------------------------------------------------MTGRKRKWGETG LIMS2_HUMAN LIMS2_HUMAN ---------------------------------------------------------MTG Q7Z4I5_HUMAN Q7Z4I5_HUMAN ------------------------------------------------------------ Q7Z4I3_HUMAN Q7Z4I3_HUMAN ------------------------------------------------------------ Q7Z4I4_HUMAN Q7Z4I4_HUMAN ------------------------------------------------------------ Q7Z4I2_HUMAN Q7Z4I2_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q8VDV4_MOUSE Q8VDV4_MOUSE ------------------------------------------------------PA---- Q9NWG2_HUMAN Q9NWG2_HUMAN S----------------------------------NMSDALANAVCQRCQARFSPAERIV B8JMJ3_DANRE B8JMJ3_DANRE -----------------------------------NMTNALANAVCERCKSSFSPTEKMV Q502G3_DANRE Q502G3_DANRE V-DGLQQNQTAGEPEVPKRSDVKVYKEFCDFYVRYNMTNALANAVCERCKSSFSPTEKMV Q4T3X4_TETNG Q4T3X4_TETNG E-TNGFQTELPVSRSQRRRSDVKVYKEFCDFYARFNMANALANAMCERCKSGFAPLEKMV B5X112_SALSA B5X112_SALSA V-V-EMTGS--------------------------NMANALANASCERCKSGFAPAEKIV Q4SHX2_TETNG Q4SHX2_TETNG ------------------------------------IANALANATCERCKSGFAATEKIV Q501W5_DANRE Q501W5_DANRE V-S-EMTGS--------------------------NMANALANASCERCKSGFAPAEKIV Q9D7B2_MOUSE Q9D7B2_MOUSE E-ANGNEDERAVSNLQRRHSDVKVYKEFCDFYAKFNMANALASATCERCKGGFAPAEKIV B4F6Z9_XENTR B4F6Z9_XENTR A-LQLKELSQSDLYRRRKERPDSLGLNGIHADKLSNMANALANAICERCRSGFAPSEKIV Q6GMB2_XENLA Q6GMB2_XENLA V-V-GMTNS--------------------------NMANALANAICERCRAGFAASEKIV A7LBJ1_XENLA A7LBJ1_XENLA V-V-GMTNS--------------------------NMANALANAICERCRSGFAPSEKIV Q6INR9_XENLA Q6INR9_XENLA V-V-GMTNS--------------------------NMANALANAICERCRSGFAPSEKIV Q5ZL81_CHICK Q5ZL81_CHICK VAAAGLPGS--------------------------NMANALANAICERCRGGFAPAEKIV Q6IYF7_CHICK Q6IYF7_CHICK ------------------------------------MANALANAICERCRGGFAPAEKIV A4FV50_BOVIN A4FV50_BOVIN V-ASGMTNS--------------------------NMANALANASCERCRGGFAPAEKIV B7Z483_HUMAN B7Z483_HUMAN V-AAGMTHS--------------------------NMANALASATCERCKGGFAPAEKIV B7Z7R3_HUMAN B7Z7R3_HUMAN E-ANGTEDERAVSKLQRRHSDVKVYKEFCDFYAKFNMANALASATCERCKGGFAPAEKIV B7Z907_HUMAN B7Z907_HUMAN LQLKELSHS--GLYRRRRDRPDSLRVNGLPEEELSNMANALASATCERCKGGFAPAEKIV LIMS1_HUMAN LIMS1_HUMAN ------------------------------------MANALASATCERCKGGFAPAEKIV A8CVP1_MOUSE A8CVP1_MOUSE Q-LKELSQS--GLYRRRRERPESLRVNGHAEEELSNMANALASATCERCKGGFAPAEKIV Q4ZJB3_MOUSE Q4ZJB3_MOUSE E-ANGNEDERAVSNLQRRHSDVKVYKEFCDFYAKFNMANALASATCERCKGGFAPAEKIV LIMS1_MOUSE LIMS1_MOUSE ------------------------------------MANALASATCERCKGGFAPAEKIV A8CVP4_MOUSE A8CVP4_MOUSE ------------------------------------MANALASATCERCKGGFAPAEKIV Q5PQM7_RAT Q5PQM7_RAT ------------------------------------MSECLADAMCQRCQARFAPTERIV LIMS2_MOUSE LIMS2_MOUSE S----------------------------------NMSECLADAMCQRCQARFAPTERIV LIMS2_BOVIN LIMS2_BOVIN S----------------------------------NMSNALANAVCQRCQARFAPAERIV B3KNZ3_HUMAN B3KNZ3_HUMAN ------------------------------------MSDALANAVCQRCQARFSPAERIV B4DMV1_HUMAN B4DMV1_HUMAN T-GSGAAPAAALRWS--------------------NMSDALANAVCQRCQARFSPAERIV LIMS2_HUMAN LIMS2_HUMAN S----------------------------------NMSDALANAVCQRCQARFSPAERIV Q7Z4I5_HUMAN Q7Z4I5_HUMAN ------------------------------------------------------------ Q7Z4I3_HUMAN Q7Z4I3_HUMAN ------------------------------------------------------------ Q7Z4I4_HUMAN Q7Z4I4_HUMAN -------ME--------------------------SRHPAVAEIACT-CWALLHPAN--- Q7Z4I2_HUMAN Q7Z4I2_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????M??ALA?A?C?RC???F?P?E??V

Q8VDV4_MOUSE Q8VDV4_MOUSE ------------------------------GKR----------TPMCAHCNQVIRGPFLV Q9NWG2_HUMAN Q9NWG2_HUMAN NSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIK B8JMJ3_DANRE B8JMJ3_DANRE NSNGELYHEQCFTCAQCFQQLIQGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFVVGRVIK Q502G3_DANRE Q502G3_DANRE NSNGELYHEQCFTCAQCFQQLIQGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFVVGRVIK Q4T3X4_TETNG Q4T3X4_TETNG NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK B5X112_SALSA B5X112_SALSA NSNGELYHEGCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK Q4SHX2_TETNG Q4SHX2_TETNG NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK Q501W5_DANRE Q501W5_DANRE NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK Q9D7B2_MOUSE Q9D7B2_MOUSE NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK B4F6Z9_XENTR B4F6Z9_XENTR NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK Q6GMB2_XENLA Q6GMB2_XENLA NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK A7LBJ1_XENLA A7LBJ1_XENLA NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK Q6INR9_XENLA Q6INR9_XENLA NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK Q5ZL81_CHICK Q5ZL81_CHICK NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK Q6IYF7_CHICK Q6IYF7_CHICK NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK A4FV50_BOVIN A4FV50_BOVIN NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK B7Z483_HUMAN B7Z483_HUMAN NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK B7Z7R3_HUMAN B7Z7R3_HUMAN NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK B7Z907_HUMAN B7Z907_HUMAN NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK LIMS1_HUMAN LIMS1_HUMAN NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK A8CVP1_MOUSE A8CVP1_MOUSE NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK Q4ZJB3_MOUSE Q4ZJB3_MOUSE NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK LIMS1_MOUSE LIMS1_MOUSE NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK A8CVP4_MOUSE A8CVP4_MOUSE NSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIK Q5PQM7_RAT Q5PQM7_RAT NSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGFCGEFVIGRVIK LIMS2_MOUSE LIMS2_MOUSE NSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGFCGEFVIGRVIK LIMS2_BOVIN LIMS2_BOVIN NSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIK B3KNZ3_HUMAN B3KNZ3_HUMAN NSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIK B4DMV1_HUMAN B4DMV1_HUMAN NSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIK LIMS2_HUMAN LIMS2_HUMAN NSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIK Q7Z4I5_HUMAN Q7Z4I5_HUMAN ------------------------------------------------------------ Q7Z4I3_HUMAN Q7Z4I3_HUMAN -----------------MPPPPAGISAGL------------------------------- Q7Z4I4_HUMAN Q7Z4I4_HUMAN ---------------------PEG------------------------------------ Q7Z4I2_HUMAN Q7Z4I2_HUMAN ------------------------------------------------------------ MATCH CONSENSUS NSNGELYHE?CF?CAQCF???PEGLFYEFEGRKYCEHDFQMLFAPCC??CGEF??GRVIK

Q8VDV4_MOUSE Q8VDV4_MOUSE ALGKSWHPEEFNCAHCKNTMAYIGFVEE-------------------------------- Q9NWG2_HUMAN Q9NWG2_HUMAN ------------------------------------------------------------ B8JMJ3_DANRE B8JMJ3_DANRE AMNSSWHPDCFCCEVCEAVLADVGFVKSGGRPLCRSCHSRQKALSLGKHVCQKCLCVVEE Q502G3_DANRE Q502G3_DANRE AMNSSWHPDCFCCEVCEAVLADVGFVKSGGRPLCRSCHSRQKALSLGKHVCQKCLCVVEE Q4T3X4_TETNG Q4T3X4_TETNG AMNNSWHPDCFCCNLCQAVLADVGFVKNAGRHLCRPCHNREKARGLGKYVCQKCHAIIEE B5X112_SALSA B5X112_SALSA AMNNSWHPDCFCCDICQAVLADVGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIED Q4SHX2_TETNG Q4SHX2_TETNG AMNNSWHPDCFCCDICQAVLADVGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIEE Q501W5_DANRE Q501W5_DANRE AMNNSWHPDCFCCDICQAVLADVGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIEE Q9D7B2_MOUSE Q9D7B2_MOUSE AMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDE B4F6Z9_XENTR B4F6Z9_XENTR AMNNSWHPECFRCDICQQVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDE Q6GMB2_XENLA Q6GMB2_XENLA AMNNSWHPECFRCDICQQVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDE A7LBJ1_XENLA A7LBJ1_XENLA AMNNSWHPECFRCDICQQVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIEE Q6INR9_XENLA Q6INR9_XENLA AMNNSWHPECFRCDICQQVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIEE Q5ZL81_CHICK Q5ZL81_CHICK AMNNSWHPDCFCCDICHKVLADIGFVKNAGRHLCRSCHNKEKARGLGKYICQKCHAIIDE Q6IYF7_CHICK Q6IYF7_CHICK AMNNSWHPDCFCCDICHKVLADIGFVKNAGRHLCRSCHNKEKARGLGKYICQKCHAIIDE A4FV50_BOVIN A4FV50_BOVIN AMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDE B7Z483_HUMAN B7Z483_HUMAN AMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDE B7Z7R3_HUMAN B7Z7R3_HUMAN AMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDE B7Z907_HUMAN B7Z907_HUMAN AMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDE LIMS1_HUMAN LIMS1_HUMAN AMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDE A8CVP1_MOUSE A8CVP1_MOUSE AMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDE Q4ZJB3_MOUSE Q4ZJB3_MOUSE AMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDE LIMS1_MOUSE LIMS1_MOUSE AMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDE A8CVP4_MOUSE A8CVP4_MOUSE AMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDE Q5PQM7_RAT Q5PQM7_RAT AMNANWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKFICQRCHLAIDE LIMS2_MOUSE LIMS2_MOUSE AMNANWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKFICQRCHLAIDE LIMS2_BOVIN LIMS2_BOVIN AMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDE B3KNZ3_HUMAN B3KNZ3_HUMAN AMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDE B4DMV1_HUMAN B4DMV1_HUMAN AMNNNWHPGCFRCELCDVELAGLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDE LIMS2_HUMAN LIMS2_HUMAN AMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDE Q7Z4I5_HUMAN Q7Z4I5_HUMAN -MNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDE Q7Z4I3_HUMAN Q7Z4I3_HUMAN ----------------------------ATRHLCRPCHNREKAKGLGKYICQRCHLVIDE Q7Z4I4_HUMAN Q7Z4I4_HUMAN -----------------------------RGHLCRPCHNREKAKGLGKYICQRCHLVIDE Q7Z4I2_HUMAN Q7Z4I2_HUMAN ------------------------------------------------------------ MATCH CONSENSUS AMN??WHP?CF?C??C???LAD?GFVK?AGRHLCR?CHNREKA?GLGK?ICQ?CH??I?E

Q8VDV4_MOUSE Q8VDV4_MOUSE -------------------------------KGALYCELCYEKFFAPECGRCQRKILGEV Q9NWG2_HUMAN Q9NWG2_HUMAN ------------------------------------------------------------ B8JMJ3_DANRE B8JMJ3_DANRE -PLMYRSDPYHPDHFNCSHCGKELTADARELKGELYCLPCHDKLGVPICGACRRPVEGRV Q502G3_DANRE Q502G3_DANRE -PLMYRSDPYHPDHFNCSHCGKELTADARELKGELYCLPCHDKLGVPICGACRRPVEGRV Q4T3X4_TETNG Q4T3X4_TETNG QPLLFKNDPYHPDHFNCNNCGKELTSDARELKGELYCLPCHDKMGVPICGACRRPIEGRV B5X112_SALSA B5X112_SALSA SPLIFKNDPYHPDHFNCNNCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV Q4SHX2_TETNG Q4SHX2_TETNG QPLIFKNDPYHPDHFNCNNCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV Q501W5_DANRE Q501W5_DANRE QPLIFKNDPYHPDHFNCSDCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV Q9D7B2_MOUSE Q9D7B2_MOUSE QPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV B4F6Z9_XENTR B4F6Z9_XENTR QPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV Q6GMB2_XENLA Q6GMB2_XENLA HPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV A7LBJ1_XENLA A7LBJ1_XENLA HPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV Q6INR9_XENLA Q6INR9_XENLA HPLIFKNDPYHPDHFNCANCGKELTADVRELKGELYCLPCHDKMGVPICGACRRPIEGRV Q5ZL81_CHICK Q5ZL81_CHICK QPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV Q6IYF7_CHICK Q6IYF7_CHICK QPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV A4FV50_BOVIN A4FV50_BOVIN QPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV B7Z483_HUMAN B7Z483_HUMAN QPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV B7Z7R3_HUMAN B7Z7R3_HUMAN QPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV B7Z907_HUMAN B7Z907_HUMAN QPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV LIMS1_HUMAN LIMS1_HUMAN QPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV A8CVP1_MOUSE A8CVP1_MOUSE QPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV Q4ZJB3_MOUSE Q4ZJB3_MOUSE QPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV LIMS1_MOUSE LIMS1_MOUSE QPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV A8CVP4_MOUSE A8CVP4_MOUSE QPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRV Q5PQM7_RAT Q5PQM7_RAT QPLMFKNDPYHPDHFSCSHCGKELTSDARELKGELYCLPCHDKMGIPICGACRRPIEGRV LIMS2_MOUSE LIMS2_MOUSE QPLMFKNDPYHPDHFSCSNCGKELTSDARELKGELYCLPCHDKMGIPICGACRRPIEGRV LIMS2_BOVIN LIMS2_BOVIN QPLMFKNDAYHPDHFSCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRV B3KNZ3_HUMAN B3KNZ3_HUMAN QPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRV B4DMV1_HUMAN B4DMV1_HUMAN QPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRV LIMS2_HUMAN LIMS2_HUMAN QPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRV Q7Z4I5_HUMAN Q7Z4I5_HUMAN QPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRV Q7Z4I3_HUMAN Q7Z4I3_HUMAN QPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRV Q7Z4I4_HUMAN Q7Z4I4_HUMAN QPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRV Q7Z4I2_HUMAN Q7Z4I2_HUMAN ---MFRSDAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRV MATCH CONSENSUS ?PL?F??D?YHPDHFNC??CGKELTA?ARELKGELYCLPCHDKMGVPICGACRRPIEGRV

Q8VDV4_MOUSE Q8VDV4_MOUSE INALKQTWHVS-------------------------------CFVCVACGKPIRNNVFHL Q9NWG2_HUMAN Q9NWG2_HUMAN ----------------------------------------------AKCEKPFLGHRHYE B8JMJ3_DANRE B8JMJ3_DANRE VNAMGKQWHVE-------------------------------HFVCVKCEKPFLGHRHYE Q502G3_DANRE Q502G3_DANRE VNAMGKQWHVE-------------------------------HFVCVKCEKPFLGHRHYE Q4T3X4_TETNG Q4T3X4_TETNG VNAMGKQWHVEHHVCTVCERPFQGHPFYERGGHAYCERHFDMHFVCAKCEKPFLGHRHYE B5X112_SALSA B5X112_SALSA VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE Q4SHX2_TETNG Q4SHX2_TETNG VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE Q501W5_DANRE Q501W5_DANRE VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE Q9D7B2_MOUSE Q9D7B2_MOUSE VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE B4F6Z9_XENTR B4F6Z9_XENTR VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE Q6GMB2_XENLA Q6GMB2_XENLA VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE A7LBJ1_XENLA A7LBJ1_XENLA VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE Q6INR9_XENLA Q6INR9_XENLA VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE Q5ZL81_CHICK Q5ZL81_CHICK VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE Q6IYF7_CHICK Q6IYF7_CHICK VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE A4FV50_BOVIN A4FV50_BOVIN VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE B7Z483_HUMAN B7Z483_HUMAN VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE B7Z7R3_HUMAN B7Z7R3_HUMAN VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE B7Z907_HUMAN B7Z907_HUMAN VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE LIMS1_HUMAN LIMS1_HUMAN VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE A8CVP1_MOUSE A8CVP1_MOUSE VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE Q4ZJB3_MOUSE Q4ZJB3_MOUSE VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE LIMS1_MOUSE LIMS1_MOUSE VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE A8CVP4_MOUSE A8CVP4_MOUSE VNAMGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE Q5PQM7_RAT Q5PQM7_RAT VNALGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE LIMS2_MOUSE LIMS2_MOUSE VNALGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE LIMS2_BOVIN LIMS2_BOVIN VNALGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE B3KNZ3_HUMAN B3KNZ3_HUMAN VNALGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE B4DMV1_HUMAN B4DMV1_HUMAN VNALGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE LIMS2_HUMAN LIMS2_HUMAN VNALGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE Q7Z4I5_HUMAN Q7Z4I5_HUMAN VNALGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE Q7Z4I3_HUMAN Q7Z4I3_HUMAN VNALGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE Q7Z4I4_HUMAN Q7Z4I4_HUMAN VNALGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE Q7Z4I2_HUMAN Q7Z4I2_HUMAN VNALGKQWHVE-------------------------------HFVCAKCEKPFLGHRHYE MATCH . * **: .: .: CONSENSUS VNA?GKQWHVE???????????????????????????????HFVCAKCEKPFLGHRHYE

Q8VDV4_MOUSE Q8VDV4_MOUSE EDGEPYCETDYYALFGTICRGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQ--- Q9NWG2_HUMAN Q9NWG2_HUMAN KKGLAYCETHYNQLFGDVCYNCSHVIE-GDV-VSALNKAWCVSCFSCSTCNSKLTLK--- B8JMJ3_DANRE B8JMJ3_DANRE RKGLAYCETHYNQLFGDVCFQCNRVIE-GDV-VSALNKAWCVRCFSCSTCTSRLTLK--- Q502G3_DANRE Q502G3_DANRE RKGLAYCETHYNQLFGDVCFQCNRVIE-GDV-VSALNKAWCVRCFSCSTCTSRLTLK--- Q4T3X4_TETNG Q4T3X4_TETNG RKGLAYCETHYNQLFGDVCYHCNRVIE-GDV-VSALNKAWCVNCFACSTCNSKLTLKDKF B5X112_SALSA B5X112_SALSA RKGLAYCETHYNQLFGDVCYHCNRVIE-GDV-VSALNKAWCVNCFSCATCNTKLTLK--- Q4SHX2_TETNG Q4SHX2_TETNG RKGLAYCETHYNQLFGDVCYHCNRVIE-GDV-VSALNKAWCVTCFSCSTCNTKLTLKDKF Q501W5_DANRE Q501W5_DANRE RKGLAYCETHYNQLFGDVCYHCNRVIE-GDV-VSALNKAWCVNCFSCSTCNTKLTLK--- Q9D7B2_MOUSE Q9D7B2_MOUSE RKGLAYCETHYNQLFGDVCFHCNRVIE-GDV-VSALNKAWCVSCFACSTCNTKLTLK--- B4F6Z9_XENTR B4F6Z9_XENTR RKGLAYCETHYNQLFGDVCFHCNRVIE-GDV-VSALNKAWCVNCFACSTCNTKLTLK--- Q6GMB2_XENLA Q6GMB2_XENLA RKGLAYCETHYNQLFGDVCFHCNRVIE-GDV-VSALNKAWCVNCFACSTCNTKLTLK--- A7LBJ1_XENLA A7LBJ1_XENLA RKGLAYCETHYNQLFGDVCFHCNRVIE-GDV-VSALNKAWCVNCFACSTCNTKLTLK--- Q6INR9_XENLA Q6INR9_XENLA RKGLAYCETHYNQLFGDVCFHCNRVIE-GDV-VSALNKAWCVNCFACSTCNTKLTLK--- Q5ZL81_CHICK Q5ZL81_CHICK RKGLAYCETHYNQLFGDVCFHCNRVIE-GDV-VSALNKAWCVNCFACSTCNTKLTLK--- Q6IYF7_CHICK Q6IYF7_CHICK RKGLAYCETHYNQLFGDVCFHCNRVIE-GDA-VSALNKAWCVNCFACSTCNTKLTLK--- A4FV50_BOVIN A4FV50_BOVIN RKGLAYCETHYNQLFGDVCFHCNRVIE-GDV-VSALNKAWCVHCFACSTCSAKLTLK--- B7Z483_HUMAN B7Z483_HUMAN RKGLAYCETHYNQLFGDVCFHCNRVIE-GDV-VSALNKAWCVNCFACSTCNTKLTLK--- B7Z7R3_HUMAN B7Z7R3_HUMAN RKGLAYCETHYNQLFGDVCFHCNRVIE-GDV-VSALNKAWCVNCFACSTCNTKLTLK--- B7Z907_HUMAN B7Z907_HUMAN RKGLAYCETHYNQLFGDVCFHCNRVIE-GDV-VSALNKAWCVNCFACSTCNTKLTLK--- LIMS1_HUMAN LIMS1_HUMAN RKGLAYCETHYNQLFGDVCFHCNRVIE-GDV-VSALNKAWCVNCFACSTCNTKLTLK--- A8CVP1_MOUSE A8CVP1_MOUSE RKGLAYCETHYNQLFGDVCFHCNRVIE-GDV-VSALNKAWCVSCFACSTCNTKLTLK--- Q4ZJB3_MOUSE Q4ZJB3_MOUSE RKGLAYCETHYNQLFGDVCFHCNRVIE-GDV-VSALNKAWCVSCFACSTCNTKLTLK--- LIMS1_MOUSE LIMS1_MOUSE RKGLAYCETHYNQLFGDVCFHCNRVIE-GDV-VSALNKAWCVSCFACSTCNTKLTLK--- A8CVP4_MOUSE A8CVP4_MOUSE RKGLAYCETHYNQLFGDVCFHCNRVIE-GDV-VSALNKAWCVSCFACSTCNTKLTLK--- Q5PQM7_RAT Q5PQM7_RAT KKGLAYCETHYNQLFGDVCYNCSHVIE-GDG-EASVPKPL-----------PPLLSP--- LIMS2_MOUSE LIMS2_MOUSE KKGLAYCETHYNQLFGDVCYNCSHVIE-GDV-VSALSKAWCVNCFSCSTCNMKLTLK--- LIMS2_BOVIN LIMS2_BOVIN KKGLAYCETHYNQLFGDVCYTCSHVIE-GDV-VSALNKAWCVHCFSCSTCNSRLTLK--- B3KNZ3_HUMAN B3KNZ3_HUMAN KKGLAYCETHYNQLFGDVCYNCSRVIE-GDV-VSALNKAWCVSCFSCSTCNSKLTLK--- B4DMV1_HUMAN B4DMV1_HUMAN KKGLAYCETHYNQLFGDVCYNCSHVIE-GDV-VSALNKAWCVSCFSCSTCNSKLTLK--- LIMS2_HUMAN LIMS2_HUMAN KKGLAYCETHYNQLFGDVCYNCSHVIE-GDV-VSALNKAWCVSCFSCSTCNSKLTLK--- Q7Z4I5_HUMAN Q7Z4I5_HUMAN KKGLAYCETHYNQLFGDVCYNCSHVIE-GDV-VSALNKAWCVSCFSCSTCNSKLTLK--- Q7Z4I3_HUMAN Q7Z4I3_HUMAN KKGLAYCETHYNQLFGDVCYNCSHVIE-GDV-VSALNKAWCVSCFSCSTCNSKLTLK--- Q7Z4I4_HUMAN Q7Z4I4_HUMAN KKGLAYCETHYNQLFGDVCYNCSHVIE-GDV-VSALNKAWCVSCFSCSTCNSKLTLK--- Q7Z4I2_HUMAN Q7Z4I2_HUMAN KKGLAYCETHYNQLFGDVCYNCSHVIE-GDV-VSALNKAWCVSCFSCSTCNSKLTLK--- MATCH ..* .****.* *** :* *. ** ** :: . * CONSENSUS ?KGLAYCETHYNQLFGDVC??C??VIE?GDV?VSALNKAWCV?CF?CSTCN?KLTLK???

Q8VDV4_MOUSE Q8VDV4_MOUSE -------------------------------------------TFFSKKDKPLCKKHAHS Q9NWG2_HUMAN Q9NWG2_HUMAN ------------------------------------------NKFVEFDMKPVCKRCYEK B8JMJ3_DANRE B8JMJ3_DANRE ------------------------------------------DKFVEIDLKPVCKHCYER Q502G3_DANRE Q502G3_DANRE ------------------------------------------DKFVEIDLKPVCKHCYER Q4T3X4_TETNG Q4T3X4_TETNG VEVDLKPVCKRCYERLPEDMKRRLARRERDSKDKKKKLPIPMNKFVEFDMKPVCKKCYEK B5X112_SALSA B5X112_SALSA ------------------------------------------NKFVEFDMKPVCKKCYEK Q4SHX2_TETNG Q4SHX2_TETNG VEIDLRPVCKHCYERMPEELKRRLARRKRDAKDRKKKPAVCLNKFVEFDMKPVCKKCYEK Q501W5_DANRE Q501W5_DANRE ------------------------------------------NKFVEFDMKPVCKKCYEK Q9D7B2_MOUSE Q9D7B2_MOUSE ------------------------------------------DKFVEIDLKPVCKYCYEK B4F6Z9_XENTR B4F6Z9_XENTR ------------------------------------------NKFVEFDMKPVCKKCYEK Q6GMB2_XENLA Q6GMB2_XENLA ------------------------------------------NKFVEFDMKPVCKKCYEK A7LBJ1_XENLA A7LBJ1_XENLA ------------------------------------------NKFVEFDMKPVCKKCYEK Q6INR9_XENLA Q6INR9_XENLA ------------------------------------------NKFVEFDMKPVCKKCYEK Q5ZL81_CHICK Q5ZL81_CHICK ------------------------------------------NKFVEFDMKPVCKKCYEK Q6IYF7_CHICK Q6IYF7_CHICK ------------------------------------------NKFVEFDMKPVCKKCYEK A4FV50_BOVIN A4FV50_BOVIN ------------------------------------------NKFVEFDMKPVCKKCYEK B7Z483_HUMAN B7Z483_HUMAN ------------------------------------------NKFVEFDMKPVCKKCYEK B7Z7R3_HUMAN B7Z7R3_HUMAN ------------------------------------------NKFVEFDMKPVCKKCYEK B7Z907_HUMAN B7Z907_HUMAN ------------------------------------------NKFVEFDMKPVCKKCYEK LIMS1_HUMAN LIMS1_HUMAN ------------------------------------------NKFVEFDMKPVCKKCYEK A8CVP1_MOUSE A8CVP1_MOUSE ------------------------------------------NKFVEFDMKPVCKECYEK Q4ZJB3_MOUSE Q4ZJB3_MOUSE ------------------------------------------NKFVEFDMKPVCKECYEK LIMS1_MOUSE LIMS1_MOUSE ------------------------------------------NKFVEFDMKPVCKKCYEK A8CVP4_MOUSE A8CVP4_MOUSE ------------------------------------------NKFVEFDMKPVCKECYEK Q5PQM7_RAT Q5PQM7_RAT ------------------------------------------NQSVLLVVGGA------- LIMS2_MOUSE LIMS2_MOUSE ------------------------------------------NKFVEFDMKPVCKRCYER LIMS2_BOVIN LIMS2_BOVIN ------------------------------------------NKFVEFDMKPVCKRCYEK B3KNZ3_HUMAN B3KNZ3_HUMAN ------------------------------------------NKFVEFDMKPVCKRGYEK B4DMV1_HUMAN B4DMV1_HUMAN ------------------------------------------NKFVEFDMKPVCKRCYEK LIMS2_HUMAN LIMS2_HUMAN ------------------------------------------NKFVEFDMKPVCKRCYEK Q7Z4I5_HUMAN Q7Z4I5_HUMAN ------------------------------------------NKFVEFDMKPVCKRCYEK Q7Z4I3_HUMAN Q7Z4I3_HUMAN ------------------------------------------NKFVEFDMKPVCKRCYEK Q7Z4I4_HUMAN Q7Z4I4_HUMAN ------------------------------------------NKFVEFDMKPVCKRCYEK Q7Z4I2_HUMAN Q7Z4I2_HUMAN ------------------------------------------NKFVEFDMKPVCKRCYEK MATCH . CONSENSUS ??????????????????????????????????????????NKFVEFDMKPVCK?CYEK

Q8VDV4_MOUSE Q8VDV4_MOUSE VNF---------------------------- Q9NWG2_HUMAN Q9NWG2_HUMAN FPLELKKRL-KKLSELTSRKAQPKATDLNSA B8JMJ3_DANRE B8JMJ3_DANRE MPDELKRRL-SREQESRDKRKRRPMCL---- Q502G3_DANRE Q502G3_DANRE MPDELKRRL-SREQESRDKRKRRPMCL---- Q4T3X4_TETNG Q4T3X4_TETNG FPLELKKRL-KKLSDAVARK----------- B5X112_SALSA B5X112_SALSA FPLELKKRL-KKLSETVGRK----------- Q4SHX2_TETNG Q4SHX2_TETNG FPLELKKRL-KKLAESLGRK----------- Q501W5_DANRE Q501W5_DANRE FPLELKKRL-KKLAETLGRK----------- Q9D7B2_MOUSE Q9D7B2_MOUSE MPEEFKRRLAKREREAKDKDKQRKRKPV--- B4F6Z9_XENTR B4F6Z9_XENTR FPLELKKRL-KKLSEPLARK----------- Q6GMB2_XENLA Q6GMB2_XENLA FPLELKKRL-KKLSEPLARK----------- A7LBJ1_XENLA A7LBJ1_XENLA FPLELKKRL-KKLSEPLAKK----------- Q6INR9_XENLA Q6INR9_XENLA FPLELKKRL-KKLSEPLAKK----------- Q5ZL81_CHICK Q5ZL81_CHICK FPLELKKRL-KKLAETVGRK----------- Q6IYF7_CHICK Q6IYF7_CHICK FPLELKKRL-KKLAETVGRK----------- A4FV50_BOVIN A4FV50_BOVIN FPLELKKRL-KKLAETLGRK----------- B7Z483_HUMAN B7Z483_HUMAN FPLELKKRL-KKLAETLGRK----------- B7Z7R3_HUMAN B7Z7R3_HUMAN FPLELKKRL-KKLAETLGRK----------- B7Z907_HUMAN B7Z907_HUMAN FPLELKKRL-KKLAETLGRK----------- LIMS1_HUMAN LIMS1_HUMAN FPLELKKRL-KKLAETLGRK----------- A8CVP1_MOUSE A8CVP1_MOUSE FPLELKKRL-KKLSETLGRK----------- Q4ZJB3_MOUSE Q4ZJB3_MOUSE FPLELKKRL-KKLSETLGRK----------- LIMS1_MOUSE LIMS1_MOUSE FPLELKKRL-KKLSETLGRK----------- A8CVP4_MOUSE A8CVP4_MOUSE FPLELKKRL-KKLSETLGRK----------- Q5PQM7_RAT Q5PQM7_RAT ----------GGVGGGLGDVGEWRNCGW--- LIMS2_MOUSE LIMS2_MOUSE FPLELKKRL-KKLSDLSSRKAQPKSVDVNSL LIMS2_BOVIN LIMS2_BOVIN FPLELKKRL-KKLSELAARRAQPKSSGLHPA B3KNZ3_HUMAN B3KNZ3_HUMAN FPLELKKRL-KKLSELTSRKAQPKATDLNSA B4DMV1_HUMAN B4DMV1_HUMAN FPLELKKRL-KKLSELTSRKAQPKATDLNSA LIMS2_HUMAN LIMS2_HUMAN FPLELKKRL-KKLSELTSRKAQPKATDLNSA Q7Z4I5_HUMAN Q7Z4I5_HUMAN FPLELKKRL-KKLSELTSRKAQPKATDLNSA Q7Z4I3_HUMAN Q7Z4I3_HUMAN FPLELKKRL-KKLSELTSRKAQPKATDLNSA Q7Z4I4_HUMAN Q7Z4I4_HUMAN FPLELKKRL-KKLSELTSRKAQPKATDLNSA Q7Z4I2_HUMAN Q7Z4I2_HUMAN FPLELKKRL-KKLSELTSRKAQPKATDLNSA MATCH CONSENSUS FPLELKKRL?KKL?E????K???????????


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