Alignment of the gene Family HBG000070 of HOVERGEN

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Isoforms are ON
A0JMC7_DANRE A0JMC7_DANRE ----------MEPSFGISE----------------SQCIATVRGHEIRSGQK-------- Q4RTB9_TETNG Q4RTB9_TETNG DGLWALLQLLLLLTAPAARAAPDLSLYLYTILRNHTAHACEGDTLAIECPPRTSVTVLSA Q08BT4_XENTR Q08BT4_XENTR ----------AEPADEPGPGKRRAGKERYSMDRHKQVPSGGVTGHELKSGRK-------- Q4R433_MACFA Q4R433_MACFA ------------------------------------------------------------ Q5R9G5_PONAB Q5R9G5_PONAB ----------MEPPLPVGA-----------------QPLATVEGMEMKGPLR-------- B7ZLX2_HUMAN B7ZLX2_HUMAN ----------MEPPLPVGA-----------------QPLATVEGMEMKGPLR-------- A6NNH7_HUMAN A6NNH7_HUMAN ----------MEPPLPVGA-----------------QPLATVEGMEMKGPLR-------- Q504W7_HUMAN Q504W7_HUMAN ----------MEPPLPVGA-----------------QPLATVEGMEMKGPLR-------- OCRL_HUMAN OCRL_HUMAN ----------MEPPLPVGA-----------------QPLATVEGMEMKGPLR-------- Q4VY10_HUMAN Q4VY10_HUMAN ----------MEPPLPVGA-----------------QPLATVEGMEMKGPLR-------- A8KAP2_HUMAN A8KAP2_HUMAN ----------MEPPLPVGA-----------------QPLATVEGMEMKGPLR-------- A7E337_BOVIN A7E337_BOVIN ----------MEPPLPIGA-----------------QPLTTIEGMEMKGPLR-------- Q8BXT3_MOUSE Q8BXT3_MOUSE -----------------------------------------------MGSMK-------- Q8BXC9_MOUSE Q8BXC9_MOUSE ----------MEPRLPIGA-----------------QPLAMVAGLEMKGPLR-------- B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE ----------MEPRLPIGA-----------------QPLAMVAGLEMKGPLR-------- Q80XM6_MOUSE Q80XM6_MOUSE ------------------------------------------------------------ Q4T009_TETNG Q4T009_TETNG ------------------------------------------------------------ Q207K8_ICTPU Q207K8_ICTPU ------------------------------------------------------------ A5LFW0_MACFA A5LFW0_MACFA ------------------------------------------------------------ B3KMW4_HUMAN B3KMW4_HUMAN ----------MSAAASSRE----------------------------------------- I5P2_HUMAN I5P2_HUMAN ----------MDQSVAIQE-----------TLAEGEYCVIAVQGVLCEGDSRQSRLLGLV Q4G006_RAT Q4G006_RAT ------------------------------------------------------------ Q91ZF8_MOUSE Q91ZF8_MOUSE ----------MDQSVAIQE-----------TLVEGEYCVIAVQGVLCKGDSRQSRLLGLV Q8CF65_MOUSE Q8CF65_MOUSE ------------------------------------------------------------ O54996_MOUSE O54996_MOUSE ----------MHEGGPVRG----------------------------------------- Q8K337_MOUSE Q8K337_MOUSE ----------MDQSVAIQE-----------TLVEGEYCVIAVQGVLCKGDSRQSRLLGLV Q9DBW2_MOUSE Q9DBW2_MOUSE ---------ALEEA---------------------------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

A0JMC7_DANRE A0JMC7_DANRE ---------------------------------------------------------EPR Q4RTB9_TETNG Q4RTB9_TETNG FYGRRVPNQHLCPSVNPNATAEEDAECTSPVAMEKVLAECQYRQSCHVPVFSPVFGLDPC Q08BT4_XENTR Q08BT4_XENTR ---------------------------------------------------------EPC Q4R433_MACFA Q4R433_MACFA ------------------------------------------------------------ Q5R9G5_PONAB Q5R9G5_PONAB ---------------------------------------------------------EPC B7ZLX2_HUMAN B7ZLX2_HUMAN ---------------------------------------------------------EPC A6NNH7_HUMAN A6NNH7_HUMAN ---------------------------------------------------------EPC Q504W7_HUMAN Q504W7_HUMAN ---------------------------------------------------------EPC OCRL_HUMAN OCRL_HUMAN ---------------------------------------------------------EPC Q4VY10_HUMAN Q4VY10_HUMAN ---------------------------------------------------------EPC A8KAP2_HUMAN A8KAP2_HUMAN ---------------------------------------------------------EPC A7E337_BOVIN A7E337_BOVIN ---------------------------------------------------------EPC Q8BXT3_MOUSE Q8BXT3_MOUSE ------------------------------------------------------------ Q8BXC9_MOUSE Q8BXC9_MOUSE ---------------------------------------------------------EPC B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE ---------------------------------------------------------EPC Q80XM6_MOUSE Q80XM6_MOUSE ------------------------------------------------------------ Q4T009_TETNG Q4T009_TETNG ------------------------------------------------------------ Q207K8_ICTPU Q207K8_ICTPU ------------------------------------------------------------ A5LFW0_MACFA A5LFW0_MACFA ------------------------------------------------------------ B3KMW4_HUMAN B3KMW4_HUMAN ------------------------------------------------------------ I5P2_HUMAN I5P2_HUMAN RYRLEHGGQEHALFLYTHRRMAITGDDVSLDQIVPVSRDFTLEEVSPDGELYILGSDVTV Q4G006_RAT Q4G006_RAT ------------------------------------------------------------ Q91ZF8_MOUSE Q91ZF8_MOUSE RYRLENDAQEHALFLYTHRRMAITGDDVSLDQIVPLSKDFMLEEVSPDGELYILGSDVTV Q8CF65_MOUSE Q8CF65_MOUSE ------------------------------------------------------------ O54996_MOUSE O54996_MOUSE ------------------------------------------------------------ Q8K337_MOUSE Q8K337_MOUSE RYRLENDAQEHALFLYTHRRMAITGDDVSLDQIVPLSKDFMLEEVSPDGELYILGSDVTV Q9DBW2_MOUSE Q9DBW2_MOUSE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A0JMC7_DANRE A0JMC7_DANRE LLS-----------LLE------------------------------------------- Q4RTB9_TETNG Q4RTB9_TETNG PLTTKYLLVSYKCRPEHHLTRLVCENERLRLACKNETVLTIYSAVFGHLLHGSPSCPQDP Q08BT4_XENTR Q08BT4_XENTR LLI-----------LSQ------------------------------------------- Q4R433_MACFA Q4R433_MACFA ------------------------------------------------------------ Q5R9G5_PONAB Q5R9G5_PONAB ALT-----------LAQ------------------------------------------- B7ZLX2_HUMAN B7ZLX2_HUMAN ALT-----------LAQ------------------------------------------- A6NNH7_HUMAN A6NNH7_HUMAN ALT-----------LAQ------------------------------------------- Q504W7_HUMAN Q504W7_HUMAN ALT-----------LAQ------------------------------------------- OCRL_HUMAN OCRL_HUMAN ALT-----------LAQ------------------------------------------- Q4VY10_HUMAN Q4VY10_HUMAN ALT-----------LAQ------------------------------------------- A8KAP2_HUMAN A8KAP2_HUMAN ALT-----------LAQ------------------------------------------- A7E337_BOVIN A7E337_BOVIN ALT-----------LVQ------------------------------------------- Q8BXT3_MOUSE Q8BXT3_MOUSE ------------------------------------------------------------ Q8BXC9_MOUSE Q8BXC9_MOUSE VLT-----------LAR------------------------------------------- B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE VLT-----------LAR------------------------------------------- Q80XM6_MOUSE Q80XM6_MOUSE ------------------------------------------------------------ Q4T009_TETNG Q4T009_TETNG ------------------------------------------------------------ Q207K8_ICTPU Q207K8_ICTPU ------------------------------------------------------------ A5LFW0_MACFA A5LFW0_MACFA ------------------------------------------------------------ B3KMW4_HUMAN B3KMW4_HUMAN ------------------------------------------------------------ I5P2_HUMAN I5P2_HUMAN QLDTAELSLVFQLPFGS------------------------------------------- Q4G006_RAT Q4G006_RAT ------------------------------------------------------------ Q91ZF8_MOUSE Q91ZF8_MOUSE QLNTAELKLVFQLPFGS------------------------------------------- Q8CF65_MOUSE Q8CF65_MOUSE ------------------------------------------------------------ O54996_MOUSE O54996_MOUSE ------------------------------------------------------------ Q8K337_MOUSE Q8K337_MOUSE QLNTAELKLVFQLPFGS------------------------------------------- Q9DBW2_MOUSE Q9DBW2_MOUSE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A0JMC7_DANRE A0JMC7_DANRE --------------------CSGQFKLDILSNPDAIVLSPVSQLSIPINNHFRIIREAEE Q4RTB9_TETNG Q4RTB9_TETNG GSHVDMGLPEKVALYFVSGICAGLVFLLCLFGLRSTLVKDVKELVSELKTSRRQQKEFMD Q08BT4_XENTR Q08BT4_XENTR -------------------LRDGQYALVIHNQGR----NSVSEDILPITSNFKFVQEAEE Q4R433_MACFA Q4R433_MACFA ------------------------------------------------------------ Q5R9G5_PONAB Q5R9G5_PONAB --------------------RNGQYELIIQLHEK----EQHVQDIIPINSHFRCVQEAEE B7ZLX2_HUMAN B7ZLX2_HUMAN --------------------RNGQYELIIQLHEK----EQHVQDIIPINSHFRCVQEAEE A6NNH7_HUMAN A6NNH7_HUMAN --------------------RNGQYELIIQLHEK----EQHVQDIIPINSHFRCVQEAEE Q504W7_HUMAN Q504W7_HUMAN --------------------RNGQYELIIQLHEK----EQHVQDIIPINSHFRCVQEAEE OCRL_HUMAN OCRL_HUMAN --------------------RNGQYELIIQLHEK----EQHVQDIIPINSHFRCVQEAEE Q4VY10_HUMAN Q4VY10_HUMAN --------------------RNGQYELIIQLHEK----EQHVQDIIPINSHFRCVQEAEE A8KAP2_HUMAN A8KAP2_HUMAN --------------------RNGQYELIIQLHEK----EQHVQDIIPINSHFRCVQEAEE A7E337_BOVIN A7E337_BOVIN --------------------RNGQYELIIQLHKK----EQRVQDIIPINSHFRCVQEAEE Q8BXT3_MOUSE Q8BXT3_MOUSE ---------------------------------------------------------AEE Q8BXC9_MOUSE Q8BXC9_MOUSE --------------------RNGQYELIIQLHGK----EQHVQDIIPINSHFRCVQEAEE B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE --------------------RNGQYELIIQLHGK----EQHVQDIIPINSHFRCVQEAEE Q80XM6_MOUSE Q80XM6_MOUSE ------------------------------------------------------------ Q4T009_TETNG Q4T009_TETNG ------------------------------------------------------------ Q207K8_ICTPU Q207K8_ICTPU ------------------------------------------------------------ A5LFW0_MACFA A5LFW0_MACFA ------------------------------------------------------------ B3KMW4_HUMAN B3KMW4_HUMAN ------------------------------------------------------------ I5P2_HUMAN I5P2_HUMAN --------------------QTRMFLHEVARACPGFDSATRDPEFLWLSRYRCAELELEM Q4G006_RAT Q4G006_RAT ------------------------------------------------------------ Q91ZF8_MOUSE Q91ZF8_MOUSE --------------------HTRTFLQEVARACPGFDPETRDPEFEWLSRHTCAEPDAES Q8CF65_MOUSE Q8CF65_MOUSE ------------------------------------------------------------ O54996_MOUSE O54996_MOUSE ------------------------------------------------------------ Q8K337_MOUSE Q8K337_MOUSE --------------------HTRTFLQEVARACPGFDPETRDPEFEWLSRHTCAEPDAES Q9DBW2_MOUSE Q9DBW2_MOUSE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A0JMC7_DANRE A0JMC7_DANRE ALLIDIDSISKT-------------------------VRIRLRGE-RTPE---------- Q4RTB9_TETNG Q4RTB9_TETNG DLFEDEVSDSSSFCRLTQSRCTTDAFTPSTLTVELAPVKIRVKGE-RAPE---------- Q08BT4_XENTR Q08BT4_XENTR TLLIDIPTNS----------G----------------CKLRVQADPWSIE---------- Q4R433_MACFA Q4R433_MACFA ------------------------------------------------------------ Q5R9G5_PONAB Q5R9G5_PONAB TLLIDIASNS----------G----------------CKIRVQGD-WIRE---------- B7ZLX2_HUMAN B7ZLX2_HUMAN TLLIDIASNS----------G----------------CKIRVQGD-WIRE---------- A6NNH7_HUMAN A6NNH7_HUMAN TLLIDIASNS----------G----------------CKIRVQGD-WIRE---------- Q504W7_HUMAN Q504W7_HUMAN TLLIDIASNS----------G----------------CKIRVQGD-WIRE---------- OCRL_HUMAN OCRL_HUMAN TLLIDIASNS----------G----------------CKIRVQGD-WIRE---------- Q4VY10_HUMAN Q4VY10_HUMAN TLLIDIASNS----------G----------------CKIRVQGD-WIRE---------- A8KAP2_HUMAN A8KAP2_HUMAN TLLIDIASNS----------G----------------CKIRVQGD-WIRE---------- A7E337_BOVIN A7E337_BOVIN TLLIDIASNS----------G----------------CKIRIQGD-WTGE---------- Q8BXT3_MOUSE Q8BXT3_MOUSE TLLIDIASNS----------G----------------CKIRVQGD-WTRE---------- Q8BXC9_MOUSE Q8BXC9_MOUSE TLLIDIASNS----------G----------------CKIRVQGD-WTRE---------- B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE TLLIDIASNS----------G----------------CKIRVQGD-WTRE---------- Q80XM6_MOUSE Q80XM6_MOUSE ------------------------------------------------------------ Q4T009_TETNG Q4T009_TETNG ------------------------------------------------------------ Q207K8_ICTPU Q207K8_ICTPU ------------------------------------------------------------ A5LFW0_MACFA A5LFW0_MACFA ------------------------------------------------------------ B3KMW4_HUMAN B3KMW4_HUMAN ------------------------------------------------------------ I5P2_HUMAN I5P2_HUMAN PTPRGCNSAL----------VTWPGYAT------IGGGRYPSRKKRWGLEEARPQGAGSV Q4G006_RAT Q4G006_RAT ------------------------------------------------------------ Q91ZF8_MOUSE Q91ZF8_MOUSE PKPREWNSDPGTRSGFAPIGG----------------SRHQSRNARRGLEDVLPRGPGYI Q8CF65_MOUSE Q8CF65_MOUSE ------------------------------------------------------------ O54996_MOUSE O54996_MOUSE ------------------------------------------------------------ Q8K337_MOUSE Q8K337_MOUSE PKPREWNSDPGTRSGFAPIGG----------------SRHQSRNARRGLEDVLPRGPGYI Q9DBW2_MOUSE Q9DBW2_MOUSE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A0JMC7_DANRE A0JMC7_DANRE LLLELQDDGQTQSFLEHVTKAKQQAERSSLPRKMEPVVPAPVKDCVPVPPQRGTSKSFSN Q4RTB9_TETNG Q4RTB9_TETNG LLLELRDDDRTQTFLTQVKSAQH------------------------------------- Q08BT4_XENTR Q08BT4_XENTR RRFEIQDEEKCMDLLAEMKLVQEGRVRHSRSEKKE------------------------- Q4R433_MACFA Q4R433_MACFA ------------------------------------------------------------ Q5R9G5_PONAB Q5R9G5_PONAB RRFEIPDEEHCLKFLSAVLAAQKAQSQLLVPEQKD------------------------- B7ZLX2_HUMAN B7ZLX2_HUMAN RRFEIPDEEHCLKFLSAVLAAQKAQSQLLVPEQKD------------------------- A6NNH7_HUMAN A6NNH7_HUMAN RRFEIPDEEHCLKFLSAVLAAQKAQSQLLVPEQKD------------------------- Q504W7_HUMAN Q504W7_HUMAN RRFEIPDEEHCLKFLSAVLAAQKAQSQLLVPEQKD------------------------- OCRL_HUMAN OCRL_HUMAN RRFEIPDEEHCLKFLSAVLAAQKAQSQLLVPEQKD------------------------- Q4VY10_HUMAN Q4VY10_HUMAN RRFEIPDEEHCLKFLSAVLAAQKAQSQLLVPEQKD------------------------- A8KAP2_HUMAN A8KAP2_HUMAN RRFEIPDEEHCLKFLSAVLAAQKAQSQLLVPEQKD------------------------- A7E337_BOVIN A7E337_BOVIN RRFEIPDEDHCVKFVSEVLAAQEAQSQLLVPDQKE------------------------- Q8BXT3_MOUSE Q8BXT3_MOUSE RHFEIPDEERCLKFLSEVLEAQEAQSQLLVPEQKD------------------------- Q8BXC9_MOUSE Q8BXC9_MOUSE RHFEIPDEERCLKFLSEVLEAQEAQSQLLVPEQKD------------------------- B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE RHFEIPDEERCLKFLSEVLEAQEAQSQLLVPEQKD------------------------- Q80XM6_MOUSE Q80XM6_MOUSE ------------------------------------------------------------ Q4T009_TETNG Q4T009_TETNG ------------------------------------------------------------ Q207K8_ICTPU Q207K8_ICTPU ------------------------------------------------------------ A5LFW0_MACFA A5LFW0_MACFA ------------------------------------------------------------ B3KMW4_HUMAN B3KMW4_HUMAN ------------------------------------------------------------ I5P2_HUMAN I5P2_HUMAN LFWGGAMEKTGFRLMERAHGGGFVWGRSARDGRRD------------------------- Q4G006_RAT Q4G006_RAT ------------------------------------------------------------ Q91ZF8_MOUSE Q91ZF8_MOUSE LLWGGAAEEPEFLLAEEMHEGGPVRGRRPLAGRRD------------------------- Q8CF65_MOUSE Q8CF65_MOUSE ------------------------------------------------------------ O54996_MOUSE O54996_MOUSE --------------------------RRPLAGRRD------------------------- Q8K337_MOUSE Q8K337_MOUSE LLWGGAAEEPEFLLAEEMHEGGPVRGRRPLAGRRD------------------------- Q9DBW2_MOUSE Q9DBW2_MOUSE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A0JMC7_DANRE A0JMC7_DANRE NINNSTLANPSNTDSTRSLA-----TDFGFEENFNHVLKVEEKKNKQNRLVAQREPPPPP Q4RTB9_TETNG Q4RTB9_TETNG ------------QDPAQTLA-----SDFGFEDSFNHSLKVEEKKNHQNRTAPPRQQPPVP Q08BT4_XENTR Q08BT4_XENTR --SSNWYQPANKTDDAGTSSKEPTEGTLGFEDNFSSVNLEKRRNIQNQQMGSRREPPPPP Q4R433_MACFA Q4R433_MACFA ------------------------------------------------------------ Q5R9G5_PONAB Q5R9G5_PONAB --SSSWYQKLDTKDKPSVFS-----GLLGLEDNFSSMNLDKKINSQNQPTGIHREPPPPP B7ZLX2_HUMAN B7ZLX2_HUMAN --SSSWYQKLDTKDKPSVFS-----GLLGFEDNFSSMNLDKKINSQNQPTGIHREPPPPP A6NNH7_HUMAN A6NNH7_HUMAN --SSSWYQKLDTKDKPSVFS-----GLLGFEDNFSSMNLDKKINSQNQPTGIHREPPPPP Q504W7_HUMAN Q504W7_HUMAN --SSSWYQKLDTKDKPSVFS-----GLLGFEDNFSSMNLDKKINSQNQPTGIHREPPPPP OCRL_HUMAN OCRL_HUMAN --SSSWYQKLDTKDKPSVFS-----GLLGFEDNFSSMNLDKKINSQNQPTGIHREPPPPP Q4VY10_HUMAN Q4VY10_HUMAN --SSSWYQKLDTKDKPSVFS-----GLLGFEDNFSSMNLDKKINSQNQPTGIHREPPPPP A8KAP2_HUMAN A8KAP2_HUMAN --SSSWYQKLDTKDKPSVFS-----GLLGFEDNFSSMNLDKKINSQNQPTGIHREPPPLP A7E337_BOVIN A7E337_BOVIN --SSSWYQKLDTKDNSSVFS-----GLLGFEDNFSSMNLDKKISLQNQPIGVHREPPPPP Q8BXT3_MOUSE Q8BXT3_MOUSE --SSSWYQKLDTMDKPA-YS-----GLLGFEDNFSSLDLDKKMNTQNPRSGSHREPPPPP Q8BXC9_MOUSE Q8BXC9_MOUSE --SSSWYQKLDTMDKPA-YS-----GLLGFEDNFSSLDLDKKMNTQNPRSGSHREPPPPP B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE --SSSWYQKLDTMDKPA-YS-----GLLGFEDNFSSLDLDKKMNTQNPRSGSHREPPPPP Q80XM6_MOUSE Q80XM6_MOUSE ------------------------------------------------------------ Q4T009_TETNG Q4T009_TETNG ------------------------------------------------------------ Q207K8_ICTPU Q207K8_ICTPU ------------------------------------------------------------ A5LFW0_MACFA A5LFW0_MACFA ------------------------------------------------------------ B3KMW4_HUMAN B3KMW4_HUMAN -------------------------RNTAGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQ I5P2_HUMAN I5P2_HUMAN --EELEEAGREMSAAAGSRE-----RNTAGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQ Q4G006_RAT Q4G006_RAT ------EADWEMSAGGGSRE-----RDCAGGYNVDSSRPNGRGLLPLDQSSGARCPDKPE Q91ZF8_MOUSE Q91ZF8_MOUSE --EALEEADWEMSAGGGSRE-----RDCAGVSNVDSSRPNGR--GPDQPSGA-RCPEKPE Q8CF65_MOUSE Q8CF65_MOUSE ------------------MK-----GKLLCVSNVDSSRPNGR--GPDQPSGA-RCPEKPE O54996_MOUSE O54996_MOUSE --EALEEADWEMSAGGGSRE-----RDCAGVSNVDSSRPNGR--GPDQPSGA-RCPEKPE Q8K337_MOUSE Q8K337_MOUSE --EALEEADWEMSAGGGSRE-----RDCAGVSNVDSSRPNGR--GPDQPSGA-RCPEKPE Q9DBW2_MOUSE Q9DBW2_MOUSE --------NWEMSAGGGSRE-----RDCAGVSNVDSSRPNGR--GPDQPSGA-RCPEKPE MATCH CONSENSUS ????????????????????????????????????????????????????????????

A0JMC7_DANRE A0JMC7_DANRE IPPLPPRKGTNTSLTGPATKERP----------PSVQNATPVRNEFQSVDRSVSWSESPS Q4RTB9_TETNG Q4RTB9_TETNG PLPLRKGPYVPSNLPPLPPAAKDRAVSIQANAFTPNAKPESFTSGFESTDRPLSWCDSPT Q08BT4_XENTR Q08BT4_XENTR P----------APVERPLPPDRE----------RDSS----------------GWEKPRV Q4R433_MACFA Q4R433_MACFA ------------------------------------------------------------ Q5R9G5_PONAB Q5R9G5_PONAB S-----------SVNKMLPREKE----------ASNK------------------EQPKV B7ZLX2_HUMAN B7ZLX2_HUMAN F-----------SVNKMLPREKE----------ASNK------------------EQPKV A6NNH7_HUMAN A6NNH7_HUMAN F-----------SVNKMLPREKE----------ASNK------------------EQPKV Q504W7_HUMAN Q504W7_HUMAN F-----------SVNKMLPREKE----------ASNK------------------EQPKV OCRL_HUMAN OCRL_HUMAN F-----------SVNKMLPREKE----------ASNK------------------EQPKV Q4VY10_HUMAN Q4VY10_HUMAN F-----------SVNKMLPREKE----------ASNK------------------EQPKV A8KAP2_HUMAN A8KAP2_HUMAN F-----------SVNKMLPREKE----------ASNK------------------EQPKV A7E337_BOVIN A7E337_BOVIN S-----------SVNRMLSREKE----------ASNK------------------EPPKV Q8BXT3_MOUSE Q8BXT3_MOUSE S-----------SSTRMLSREKE----------ASNK------------------EQPKV Q8BXC9_MOUSE Q8BXC9_MOUSE S-----------SSTRMLSREKE----------ASNK------------------EQPKV B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE S-----------SSTRMLSREKE----------ASNK------------------EQPKV Q80XM6_MOUSE Q80XM6_MOUSE ------------------------------------------------------------ Q4T009_TETNG Q4T009_TETNG ------------------------------------------------------------ Q207K8_ICTPU Q207K8_ICTPU ------------------------------------------------------------ A5LFW0_MACFA A5LFW0_MACFA ------------------------------------------------------------ B3KMW4_HUMAN B3KMW4_HUMAN P--------------RQNKSKSE----------ITDM-----------------VRSSTI I5P2_HUMAN I5P2_HUMAN P--------------RQNKSKSE----------ITDM-----------------VRSSTI Q4G006_RAT Q4G006_RAT N-----------SLTRQNRSKAE----------ITDM-----------------VRSSTI Q91ZF8_MOUSE Q91ZF8_MOUSE N-----------SLTRQNKSKSD----------MSEK-----------------VRSATV Q8CF65_MOUSE Q8CF65_MOUSE N-----------SLTRQNKSKSD----------MSEK-----------------VRSATV O54996_MOUSE O54996_MOUSE N-----------SLTRQNKSKSD----------MSEK-----------------VRSATV Q8K337_MOUSE Q8K337_MOUSE N-----------SLTRQNKSKSD----------MSEK-----------------VRSATV Q9DBW2_MOUSE Q9DBW2_MOUSE N-----------SLTRQNKSKSD----------MSEK-----------------VRSATV MATCH CONSENSUS ????????????????????????????????????????????????????????????

A0JMC7_DANRE A0JMC7_DANRE NSTIRQAMM-SSHAGSREGLLKYRLSKKEKEYVDIENFKFFVGTWNVNGQSPDSSLGPWL Q4RTB9_TETNG Q4RTB9_TETNG SNTMRHAMF-SSQAGQREYLIKHRLGKKESEYVDIKCFRFFTGTWNVNGQSPDSSLEPWL Q08BT4_XENTR Q08BT4_XENTR TNSMRKLFTPNTQSGQREGLIKHILAKKENDYVNIKNFRFFVGTWNVNGQSPDGGLEPWL Q4R433_MACFA Q4R433_MACFA ------------------------------------------------------------ Q5R9G5_PONAB Q5R9G5_PONAB TNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWL B7ZLX2_HUMAN B7ZLX2_HUMAN TNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWL A6NNH7_HUMAN A6NNH7_HUMAN TNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWL Q504W7_HUMAN Q504W7_HUMAN TNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWL OCRL_HUMAN OCRL_HUMAN TNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWL Q4VY10_HUMAN Q4VY10_HUMAN TNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWL A8KAP2_HUMAN A8KAP2_HUMAN TNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWL A7E337_BOVIN A7E337_BOVIN TNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWL Q8BXT3_MOUSE Q8BXT3_MOUSE TNTMRKLFVPNTQTGQREGLIKHILTKREKEYVNIQSFRFFVGTWNVNGQSPDSSLEPWL Q8BXC9_MOUSE Q8BXC9_MOUSE TNTMRKLFVPNTQTGQREGLIKHILTKREKEYVNIQSFRFFVGTWNVNGQSPDSSLEPWL B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE TNTMRKLFVPNTQTGQREGLIKHILTKREKEYVNIQSFRFFVGTWNVNGQSPDSSLEPWL Q80XM6_MOUSE Q80XM6_MOUSE ------------------------------------------------------------ Q4T009_TETNG Q4T009_TETNG ------------------------------------------------------------ Q207K8_ICTPU Q207K8_ICTPU ------------------------------------------------------------ A5LFW0_MACFA A5LFW0_MACFA ------------------------------------------------------------ B3KMW4_HUMAN B3KMW4_HUMAN TVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWL I5P2_HUMAN I5P2_HUMAN TVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWL Q4G006_RAT Q4G006_RAT TVSDKAHILSMQKFGLRDTMVRSHLLQKEGEYTYIQNFRFFVGTYNVNGQSPKECLRPWL Q91ZF8_MOUSE Q91ZF8_MOUSE TVSDKAHILSVQKFGLRDTIVRSHLVQKEENYTYIQNFRFFVGTYNVNGQSPKECLRPWL Q8CF65_MOUSE Q8CF65_MOUSE TVSDKAHILSVQKFGLRDTIVRSHLVQKEENYTYIQNFRFFVGTYNVNGQSPKECLRPWL O54996_MOUSE O54996_MOUSE TVSDKAHILSVQKFGLRDTIVRSHLVQKEENYTYIQNFRFFVGTYNVNGQSPKECLRPWL Q8K337_MOUSE Q8K337_MOUSE TVSDKAHILSVQKFGLRDTIVRSHLVQKEENYTYIQNFRFFVGTYNVNGQSPKECLRPWL Q9DBW2_MOUSE Q9DBW2_MOUSE TVSDKAHILSVQKFGLRDTIVRSHLVQKEENYTYIQNFRFFVGTYNVNGQSPKECLRPWL MATCH CONSENSUS ????????????????????????????????????????????????????????????

A0JMC7_DANRE A0JMC7_DANRE SSDPDPPDVYALGFQELDLSTEAFFYMDSSKEQLWVDAVERGLHQKARYIQVRIIRLVGM Q4RTB9_TETNG Q4RTB9_TETNG CCDPEPPDIYALGFQELDLSTEAFFYMDSSKEQLWVEAVERSLHPKAKYKRVRIIRLVGM Q08BT4_XENTR Q08BT4_XENTR QADAEPPDVYVIGFQELDLSTEAFFYFDSGKEQEWLEAVERCLHTKAKYKNVRLIRLVGM Q4R433_MACFA Q4R433_MACFA ------------------------------------MAVERGLHSKAKYKKVQLVRLVGM Q5R9G5_PONAB Q5R9G5_PONAB NCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLERLVGM B7ZLX2_HUMAN B7ZLX2_HUMAN NCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVEM A6NNH7_HUMAN A6NNH7_HUMAN NCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGM Q504W7_HUMAN Q504W7_HUMAN NCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGM OCRL_HUMAN OCRL_HUMAN NCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGM Q4VY10_HUMAN Q4VY10_HUMAN NCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGM A8KAP2_HUMAN A8KAP2_HUMAN NCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGM A7E337_BOVIN A7E337_BOVIN NCDLNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSLAVERSLHSKAKYKKVQLVRLVGM Q8BXT3_MOUSE Q8BXT3_MOUSE DCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSLAVERGLPSKAKYRKVQLVRLVGM Q8BXC9_MOUSE Q8BXC9_MOUSE DCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSLAVERGLPSKAKYRKVQLVRLVGM B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE DCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSLAVERGLPSKAKYRKVQLVRLVGM Q80XM6_MOUSE Q80XM6_MOUSE ------------------------------------------------------------ Q4T009_TETNG Q4T009_TETNG ------------------------------------------------------------ Q207K8_ICTPU Q207K8_ICTPU ------------------------------------------------------------ A5LFW0_MACFA A5LFW0_MACFA ------------------------------------------------------------ B3KMW4_HUMAN B3KMW4_HUMAN SNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGI I5P2_HUMAN I5P2_HUMAN SNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGI Q4G006_RAT Q4G006_RAT SSDTKAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSESLHPDAKYAKVKLIRLVGI Q91ZF8_MOUSE Q91ZF8_MOUSE SHSALAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSESLHPDAKYAKVKFVRLVGI Q8CF65_MOUSE Q8CF65_MOUSE SHSALAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSESLHPDAKYAKVKFVRLVGI O54996_MOUSE O54996_MOUSE SHSALAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSESLHPDAKYAKVKFVRLVGI Q8K337_MOUSE Q8K337_MOUSE SHSALAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSESLHPDAKYAKVKFVRLVGI Q9DBW2_MOUSE Q9DBW2_MOUSE SHSALAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSESLHPDAKYAKVKFVRLVGI MATCH CONSENSUS ?????????????????????????????????????AV???L???A?Y??V???RLV??

A0JMC7_DANRE A0JMC7_DANRE MLVVYIKKEHKDQIREIASESVGTGLMNKMGNKGGVAVRFVFHNTSFCFVNSHLAAHVDD Q4RTB9_TETNG Q4RTB9_TETNG MLVVFVRKSLVKHIKEVAAEHVGTGIMGKMGNKGGVAVRFVFHNTSFCIVNSHLAAHVED Q08BT4_XENTR Q08BT4_XENTR MMLVFAKHEHFKHIREVVAESVGTGIMGKMGNKGGVAVRFVFHNTSFCFVNSHLAAHVED Q4R433_MACFA Q4R433_MACFA MLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVED Q5R9G5_PONAB Q5R9G5_PONAB MLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHMED B7ZLX2_HUMAN B7ZLX2_HUMAN MLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVED A6NNH7_HUMAN A6NNH7_HUMAN MLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVED Q504W7_HUMAN Q504W7_HUMAN MLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVED OCRL_HUMAN OCRL_HUMAN MLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVED Q4VY10_HUMAN Q4VY10_HUMAN MLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVED A8KAP2_HUMAN A8KAP2_HUMAN MLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVED A7E337_BOVIN A7E337_BOVIN MLLIFARKDQLRYIRDVATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEE Q8BXT3_MOUSE Q8BXT3_MOUSE MLLIFARKDQCQYIRDVATETTGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEE Q8BXC9_MOUSE Q8BXC9_MOUSE MLLIFARKDQCQYIRDVATETTGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEE B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE MLLIFARKDQCQYIRDVATETTGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEE Q80XM6_MOUSE Q80XM6_MOUSE ------------------------------------------------------------ Q4T009_TETNG Q4T009_TETNG ------------------------------------------------------------ Q207K8_ICTPU Q207K8_ICTPU -------------ISEVEAETVGTGIMGRMGNKGAVAISFKFHNSDICIVDSHLAAHIEE A5LFW0_MACFA A5LFW0_MACFA MLLLYVKQEHAAYVSEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEE B3KMW4_HUMAN B3KMW4_HUMAN MLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEE I5P2_HUMAN I5P2_HUMAN MLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEE Q4G006_RAT Q4G006_RAT MLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQLHNTSICVVNSHLAAHTEE Q91ZF8_MOUSE Q91ZF8_MOUSE MLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQLHNTSICVVNSHLAAHTEE Q8CF65_MOUSE Q8CF65_MOUSE MLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQLHNTSICVVNSHLAAHTEE O54996_MOUSE O54996_MOUSE MLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQLHNTSICVVNSHLAAHTEE Q8K337_MOUSE Q8K337_MOUSE MLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQLHNTSICVVNSHLAAHTEE Q9DBW2_MOUSE Q9DBW2_MOUSE MLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQLHNTSICVVNSHLAAHTEE MATCH CONSENSUS ML???????????I?????E??GTGIMG?MGNKGGVA?RF??HNT??C?VNSHLAAH?E?

A0JMC7_DANRE A0JMC7_DANRE FERRNQDYKDICARMSFHLLE--YPPVSIVKHDVVIWLGDLNYRLCLPDAGEVKRLIAEK Q4RTB9_TETNG Q4RTB9_TETNG FERRNQDYKDICARMTFHLLE--HPPLGIVKHDVVVWLGDLNYRLFMYDAGDVKQLIAKR Q08BT4_XENTR Q08BT4_XENTR FERRNQDYKDICARLNFTVPDQNIPISNIMKHDVVIWLGDLNYRLCKFDAAEVKSLIAKN Q4R433_MACFA Q4R433_MACFA FERRNQDYKDICARMSFVVPNQTLPQLNIMKHDVVIWLGDLNYRLCMPDANEVKSLINKK Q5R9G5_PONAB Q5R9G5_PONAB FERRNQDYKDICARMSFVVPNQTLPQLNIMKHDVVIWLGDLNYRLCMPDANEVKSLINKK B7ZLX2_HUMAN B7ZLX2_HUMAN FERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKK A6NNH7_HUMAN A6NNH7_HUMAN FERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKK Q504W7_HUMAN Q504W7_HUMAN FERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLGMPDANEVKSLINKK OCRL_HUMAN OCRL_HUMAN FERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKK Q4VY10_HUMAN Q4VY10_HUMAN FERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKK A8KAP2_HUMAN A8KAP2_HUMAN FERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKK A7E337_BOVIN A7E337_BOVIN FERRNQDYKDICARMSFVVPNQTLPQLNIMKHDVVIWLGDLNYRLCMPDASEVKSLINKN Q8BXT3_MOUSE Q8BXT3_MOUSE FERRNQDYKDICARMTFSVPNQTVPQVNIMKHDVVIWLGDLNYRLCMPDASEVKSLINKN Q8BXC9_MOUSE Q8BXC9_MOUSE FERRNQDYKDICARMTFSVPNQTVPQVNIMKHDVVIWLGDLNYRLCMPDASEVKSLINKN B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE FERRNQDYKDICARMTFSVPNQTVPQVNIMKHDVVIWLGDLNYRLCMPDASEVKSLINKN Q80XM6_MOUSE Q80XM6_MOUSE ------------------------------------------------------------ Q4T009_TETNG Q4T009_TETNG ------------------------------------------------------------ Q207K8_ICTPU Q207K8_ICTPU YERRNQDYKDICSRMLFRQLDLALPPLTIMKHSVVLWIGDLNYRISDLEVDHVKDLILKD A5LFW0_MACFA A5LFW0_MACFA YERRNQDYKDICSRMQFCQLDPSRPPLTISKHDVILWLGDLNYRIEELDVEKVKKLIEEK B3KMW4_HUMAN B3KMW4_HUMAN YERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLIEEK I5P2_HUMAN I5P2_HUMAN YERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLIEEK Q4G006_RAT Q4G006_RAT YERRNQDYRDICSRMQFSQVDPSLPPLTISKHDVILWLGDLNYRIEELDVEKVKKLVEEK Q91ZF8_MOUSE Q91ZF8_MOUSE YERRNQDYRDICSRMQFPQVDPSQPPLTINKHDVILWLGDLNYRIEELDVGKVKKLVEEK Q8CF65_MOUSE Q8CF65_MOUSE YERRNQDYRDICSRMQFPQVDPSQPPLTINKHDVILWLGDLNYRIEELDVGKVKKLVEEK O54996_MOUSE O54996_MOUSE YERRNQDYRDICSRMQFPQVDPSQPPLTINKHDVILWLGDLNYRIEELDVGKVKKLVEEK Q8K337_MOUSE Q8K337_MOUSE YERRNQDYRDICSRMQFPQVDPSQPPLTINKHDVILWLGDLNYRIEELDVGKVKKLVEEK Q9DBW2_MOUSE Q9DBW2_MOUSE YERRNQDYRDICSRMQFPQVDPSQPPLTINKHDVILWLGDLNYRIEELDVGKVKKLVEEK MATCH CONSENSUS ?ERRNQDY?DIC?RM?F???????P???I?KH?V??WLGDLNYR????D???VK?L????

A0JMC7_DANRE A0JMC7_DANRE ELRRLQEYDQLNLQRKTKRVFTDFMEGEINFIPTYKYDAKSDRWDSSGKCRIPAWCDRIL Q4RTB9_TETNG Q4RTB9_TETNG ELKKLQEFDQLNHQRQTNKAFSDFMEGEINFIPTYKYDPKTDRWDSSGKCRVPAWCDRIL Q08BT4_XENTR Q08BT4_XENTR DIQTLLKYDQLNIQREMKNVFSDFTEGTINFIPTYKFDAKTDRWDSSGKCRVPAWCDRVL Q4R433_MACFA Q4R433_MACFA DLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRIL Q5R9G5_PONAB Q5R9G5_PONAB DLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRIL B7ZLX2_HUMAN B7ZLX2_HUMAN DLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRIL A6NNH7_HUMAN A6NNH7_HUMAN DLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRIL Q504W7_HUMAN Q504W7_HUMAN DLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRIL OCRL_HUMAN OCRL_HUMAN DLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRIL Q4VY10_HUMAN Q4VY10_HUMAN DLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRIL A8KAP2_HUMAN A8KAP2_HUMAN DLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRIL A7E337_BOVIN A7E337_BOVIN DLQRLLKFDQLNIQRTQKKAFADFMEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRIL Q8BXT3_MOUSE Q8BXT3_MOUSE ELHKLLKFDQLNIQRTQKKAFADFNEGEINFVPTYKYDSKTDRWDSSGKCRVPAWCDRIL Q8BXC9_MOUSE Q8BXC9_MOUSE ELHKLLKFDQLNIQRTQKKAFADFNEGEINFVPTYKYDSKTDRWDSSGKCRVPAWCDRIL B1AVT5_MOUSE B1AVT5_MOUSE ----LLKFDQLNIQRTQKKAFADFNEGEINFVPTYKYDSKTDRWDSSGKCRVPAWCDRIL Q6NVF0_MOUSE Q6NVF0_MOUSE ELHKLLKFDQLNIQRTQKKAFADFNEGEINFVPTYKYDSKTDRWDSSGKCRVPAWCDRIL Q80XM6_MOUSE Q80XM6_MOUSE ---------------------------------TYKYDSKTDRWDSSGKCRVPAWCDRIL Q4T009_TETNG Q4T009_TETNG ------------------------------------------------------------ Q207K8_ICTPU Q207K8_ICTPU DFETLHNHDQLKRQMDEEAVFVGFMEGEIDFQPTYKYDTGSDEWDTSEKCRVPAWCDRIL A5LFW0_MACFA A5LFW0_MACFA DFQTLYACDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRIL B3KMW4_HUMAN B3KMW4_HUMAN DFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRIL I5P2_HUMAN I5P2_HUMAN DFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRIL Q4G006_RAT Q4G006_RAT AFHTLYAHDQLKIQVAAKTVFEGFTEGEITFQPTYKYDTGSDNWDTSEKCRAPAWCDRVL Q91ZF8_MOUSE Q91ZF8_MOUSE AFQTLYAHDQLKIQVAARTIFDGFTEGEITFQPTYKYDTGSDDWDTSEKCRAPAWCDRIL Q8CF65_MOUSE Q8CF65_MOUSE AFQTLYAHDQLKIQVAARTIFDGFTEGEITFQPTYKYDTGSDDWDTSEKCRAPAWCDRIL O54996_MOUSE O54996_MOUSE AFQTLYAHDQLKIQVAARTIFDGFTEGEITFQPTYKYDTGSDDWDTSEKCRAPAWCDRIL Q8K337_MOUSE Q8K337_MOUSE AFQTLYAHDQLKIQVAARTIFDGFTEGEITFQPTYKYDTGSDDWDTSEKCRAPAWCDRIL Q9DBW2_MOUSE Q9DBW2_MOUSE AFQTLYAHDQLKIQVAARTIFDGFTEGEITFQPTYKYDTGSDDWDTSEKCRAPAWCDRIL MATCH CONSENSUS ????L???DQL?IQ??????F??F?EGEI?F?PTYKYD???D?WD?S?KCR?PAWCDRIL

A0JMC7_DANRE A0JMC7_DANRE WRGSNVKQLHYRSHMELKTSDHKPVSSVFSIG---------------------------- Q4RTB9_TETNG Q4RTB9_TETNG WRGNNVKQLKYRSHMDLQTSDHKPVSALFEIG---------------------------- Q08BT4_XENTR Q08BT4_XENTR WRGTNITQLKYRSHMELKTSDHKPVSSLFSIG---------------------------- Q4R433_MACFA Q4R433_MACFA WRGTNVNQLNYRSHMELKTSDHKPVSALFHIG---------------------------- Q5R9G5_PONAB Q5R9G5_PONAB WRGTNVNQLNYRSHMELKTSDHKPVSALFHIG---------------------------- B7ZLX2_HUMAN B7ZLX2_HUMAN WRGTNVNQLNYRSHMELKTSDHKPVSALFHIG---------------------------- A6NNH7_HUMAN A6NNH7_HUMAN WRGTNVNQLNYRSHMELKTSDHKPVSALFHIG---------------------------- Q504W7_HUMAN Q504W7_HUMAN WRGTNVNQLNYRSHMELKTSDHKPVSALFHIG---------------------------- OCRL_HUMAN OCRL_HUMAN WRGTNVNQLNYRSHMELKTSDHKPVSALFHIG---------------------------- Q4VY10_HUMAN Q4VY10_HUMAN WRGTNVNQLNYRSHMELKTSDHKPVSALFHIG---------------------------- A8KAP2_HUMAN A8KAP2_HUMAN WRGTNVNQLNYRSHMELKTSDHKPVSALFHIG---------------------------- A7E337_BOVIN A7E337_BOVIN WRGINVNQLHYRSHMELKTSDHKPVSALFCIG---------------------------- Q8BXT3_MOUSE Q8BXT3_MOUSE WRGINVNQLHYRSHMELKTSDHKPVSALFHIG---------------------------- Q8BXC9_MOUSE Q8BXC9_MOUSE WRGINVNQLHYRSHMELKTSDHKPVSALFHIG---------------------------- B1AVT5_MOUSE B1AVT5_MOUSE WRGINVNQLHYRSHMELKTSDHKPVSALFHIGTHQKRPSDPITDGCEPPCGCWELNSGPL Q6NVF0_MOUSE Q6NVF0_MOUSE WRGINVNQLHYRSHMELKTSDHKPVSALFHIG---------------------------- Q80XM6_MOUSE Q80XM6_MOUSE WRGINVNQLHYRSHMELKTSDHKPVSALFHIG---------------------------- Q4T009_TETNG Q4T009_TETNG ----------------XKISDHKPVSSLLITG---------------------------- Q207K8_ICTPU Q207K8_ICTPU WRGKNITQRSYQSHMTVRNSDHKPVSSLLEIG---------------------------- A5LFW0_MACFA A5LFW0_MACFA WKGKNITQLSYQSHMALKTSDHKPVSSVFNIG---------------------------- B3KMW4_HUMAN B3KMW4_HUMAN WKGKNITQLSYQSHMALKTSDHKPVSSVFDIG---------------------------- I5P2_HUMAN I5P2_HUMAN WKGKNITQLSYQSHMALKTSDHKPVSSVFDIG---------------------------- Q4G006_RAT Q4G006_RAT WRGKNISQLSYQSHMSLKTSDHKPVSSVFEIG---------------------------- Q91ZF8_MOUSE Q91ZF8_MOUSE WKGKNITQLSYQSHMALKTSDHKPVSSVFDIG---------------------------- Q8CF65_MOUSE Q8CF65_MOUSE WKGKNITQLSYQSHMALKTSDHKPVSSVFDIG---------------------------- O54996_MOUSE O54996_MOUSE WKGKNITQLSYQSHMALKTSDHKPVSSVFDIG---------------------------- Q8K337_MOUSE Q8K337_MOUSE WKGKNITQLSYQSHMALKTSDHKPVSSVFDIG---------------------------- Q9DBW2_MOUSE Q9DBW2_MOUSE WKGKNITQLSYQSHMALKTSDHKPVSSVFDIG---------------------------- MATCH : *******::: * CONSENSUS W?G?N??QL?Y?SHM?LKTSDHKPVS??F?IG????????????????????????????

A0JMC7_DANRE A0JMC7_DANRE ---------------------VKMVIEQRYKKIFEEIVRDMDRMENDFLPSLSLTRREFT Q4RTB9_TETNG Q4RTB9_TETNG ---------------------VKVVNEERQKKVFEEIVRAMDRIENEFLPSVSLSRREFT Q08BT4_XENTR Q08BT4_XENTR ---------------------VKVVDERRYRKAFEDIVRMMDRMENEFLPSLNLSRREFV Q4R433_MACFA Q4R433_MACFA ---------------------VKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFV Q5R9G5_PONAB Q5R9G5_PONAB ---------------------VKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFV B7ZLX2_HUMAN B7ZLX2_HUMAN ---------------------VKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFV A6NNH7_HUMAN A6NNH7_HUMAN ---------------------VKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFV Q504W7_HUMAN Q504W7_HUMAN ---------------------VKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFV OCRL_HUMAN OCRL_HUMAN ---------------------VKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFV Q4VY10_HUMAN Q4VY10_HUMAN ---------------------VKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFV A8KAP2_HUMAN A8KAP2_HUMAN ---------------------VKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFV A7E337_BOVIN A7E337_BOVIN ---------------------VKVVDERRYRKVFEDIVRIMDRMENDFLPSLELSRRQFV Q8BXT3_MOUSE Q8BXT3_MOUSE ---------------------VKVVDERRYRKVFEDIVRIMDRMENDFLPSLELSRRE-- Q8BXC9_MOUSE Q8BXC9_MOUSE ---------------------VKVVDERRYRKVFEDIVRIMDRMENDFLPSLELSRREFF B1AVT5_MOUSE B1AVT5_MOUSE EEQSVLLTAEPSLQPSPMYLMVKVVDERRYRKVFEDIVRIMDRMENDFLPSLELSRREFF Q6NVF0_MOUSE Q6NVF0_MOUSE ---------------------VKVVDERRYRKVFEDIVRIMDRMENDFLPSLELSRREFF Q80XM6_MOUSE Q80XM6_MOUSE ---------------------VKVVDERRYRKVFEDIVRIMDRMENDFLPSLELSRREFF Q4T009_TETNG Q4T009_TETNG ---------------------IKRVNSEAYKKTFEEIVRNIDKMENECIPSVLLAKQEFY Q207K8_ICTPU Q207K8_ICTPU ---------------------IKVVNEEIYKRTFEDIVRSLDKLENECIPSVSLSEREFI A5LFW0_MACFA A5LFW0_MACFA ---------------------VRVVNDELYRKTLEEIVRSLDKMENANIPSVSLSKREFC B3KMW4_HUMAN B3KMW4_HUMAN ---------------------VRVVNDELYRKTLEEIVRSLDKMENANIPSVSLSKREFC I5P2_HUMAN I5P2_HUMAN ---------------------VRVVNDELYRKTLEEIVRSLDKMENANIPSVSLSKREFC Q4G006_RAT Q4G006_RAT ---------------------VRVVNEELYRKTLEEIVRSLDKMENANIPSVTLSKREFC Q91ZF8_MOUSE Q91ZF8_MOUSE ---------------------VRVVNEELYRKTLEEIVRSLDKMENANIPSVTLSKREFC Q8CF65_MOUSE Q8CF65_MOUSE ---------------------VRVVNEELYRKTLEEIVRSLDKMENANIPSVTLSKREFC O54996_MOUSE O54996_MOUSE ---------------------VRVVNEELYRKTLEEIVRSLDKMENANIPSVTLSKREFC Q8K337_MOUSE Q8K337_MOUSE ---------------------VRVVNEELYRKTLEEIVRSLDKMENANIPSVTLSKREFC Q9DBW2_MOUSE Q9DBW2_MOUSE ---------------------VRVVNEELYRKTLEEIVRSLDKMENANIPSVTLSKREFC MATCH :: * .. :: :*: ** :*::** :**: *:.:: CONSENSUS ?????????????????????V?VV?E??YRK??E??VR??D?MEN???PS??LS?REF?

A0JMC7_DANRE A0JMC7_DANRE FENVKFRQLQRQSFLITNDGQVACTFAFIPKLNDSQYCKPWLRAEPCEGVLDPNEKIEIF Q4RTB9_TETNG Q4RTB9_TETNG FENVKFRRLQKDRFLITNDGQVPCHFAFIPKLNDSQYCKPWLRAEPSDGFLEPNETLEIY Q08BT4_XENTR Q08BT4_XENTR FERVRFRQLQKEKFQIKNDGQVTCHFSFIPKLNDTQYCKPWLRAEPCEGYLEPEETVDIS Q4R433_MACFA Q4R433_MACFA FENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDIS Q5R9G5_PONAB Q5R9G5_PONAB FENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDIS B7ZLX2_HUMAN B7ZLX2_HUMAN FENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDIS A6NNH7_HUMAN A6NNH7_HUMAN FENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDIS Q504W7_HUMAN Q504W7_HUMAN FENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDIS OCRL_HUMAN OCRL_HUMAN FENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDIS Q4VY10_HUMAN Q4VY10_HUMAN FENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDIS A8KAP2_HUMAN A8KAP2_HUMAN FENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDIS A7E337_BOVIN A7E337_BOVIN FENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPCEGYLEPNETVDIS Q8BXT3_MOUSE Q8BXT3_MOUSE ------------------------------------------------------------ Q8BXC9_MOUSE Q8BXC9_MOUSE FENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETLDIS B1AVT5_MOUSE B1AVT5_MOUSE FENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETLDIS Q6NVF0_MOUSE Q6NVF0_MOUSE FENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETLDIS Q80XM6_MOUSE Q80XM6_MOUSE FENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETLDIS Q4T009_TETNG Q4T009_TETNG FKDVKYMQHQAKTLTVYNDGQVPCQFEFIQKPNESTYCKPWLTANPPKGFIAQGGSVDIE Q207K8_ICTPU Q207K8_ICTPU FNNVKFMQHQAKTLTLHNDGQ--------------------------------------- A5LFW0_MACFA A5LFW0_MACFA FQNVKYMQLKVESFTIHN-GQVPCHFEFINKPDEESYCKQWLNANPSRGFLLPDSDIEIE B3KMW4_HUMAN B3KMW4_HUMAN FQNVKYMQLKVESFTIHN-GQVPCHFEFINKPDEESYCKQWLNANPSRGFLLPDSDVEID I5P2_HUMAN I5P2_HUMAN FQNVKYMQLKVESFTIHN-GQVPCHFEFINKPDEESYCKQWLNANPSRGFLLPDSDVEID Q4G006_RAT Q4G006_RAT FENVKYMQLQTATFTIHN-GQVPCEFEFINKPDEETYCKQWLTAKPSRGFLLPDSHVEIE Q91ZF8_MOUSE Q91ZF8_MOUSE FENVKYMQLQTESFTIHN-SQVPCQFEFINKPDEESYCKQWLTARPSKGFLLPDSHVEIE Q8CF65_MOUSE Q8CF65_MOUSE FENVKYMQLQTESFTIHN-SQVPCQFEFINKPDEESYCKQWLTARPSKGFLLPDSHVEIE O54996_MOUSE O54996_MOUSE FENVKYMQLQTESFTIHN-SQVPCQFEFINKPDEESYCKQWLTARPSKGFLLPDSHVEIE Q8K337_MOUSE Q8K337_MOUSE FENVKYMQLQTESFTIHN-SQVPCQFEFINKPDEESYCKQWLTARPSKGFLLPDSHVEIE Q9DBW2_MOUSE Q9DBW2_MOUSE FENVKYMQLQTESFTIHN-SQVPCQFEFINKPDEESYCKQWLTARPSKGFLLPDSHVEIE MATCH CONSENSUS F?NVK??QLQ???F?I?N??QVPC?F?FI?K?????YCK?WL?A?P??G?L?P?????I?

A0JMC7_DANRE A0JMC7_DANRE LEVYVSKDSVTLLNSGEDNIEDILVLHLDRGKDYFITVSGNYLPSCFGTSLETLCRMKKP Q4RTB9_TETNG Q4RTB9_TETNG LEVYVSKDSVTLLNSGEDSIEDILVLHLDRGKDYFITIFGNYLPSCFGTSLEALCRMKKP Q08BT4_XENTR Q08BT4_XENTR LEVYVSKDSVTMLNSEEDKIEDILVLHLDRGKDYFLTISGSYLVSCFGTSLEALCRMKRP Q4R433_MACFA Q4R433_MACFA LDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRP Q5R9G5_PONAB Q5R9G5_PONAB LDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRP B7ZLX2_HUMAN B7ZLX2_HUMAN LDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRP A6NNH7_HUMAN A6NNH7_HUMAN LDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRP Q504W7_HUMAN Q504W7_HUMAN LDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRP OCRL_HUMAN OCRL_HUMAN LDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRP Q4VY10_HUMAN Q4VY10_HUMAN LDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRP A8KAP2_HUMAN A8KAP2_HUMAN LDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRP A7E337_BOVIN A7E337_BOVIN LDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRP Q8BXT3_MOUSE Q8BXT3_MOUSE ------------------------------------------------------------ Q8BXC9_MOUSE Q8BXC9_MOUSE LDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTIGGNYLPSCFGTSLEALCRMKRP B1AVT5_MOUSE B1AVT5_MOUSE LDVYVSKDSVTILNSGEDKIEDILVLHLDR------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE LDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTIGGNYLPSCFGTSLEALCRMKRP Q80XM6_MOUSE Q80XM6_MOUSE LDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTIGGNYLPSCFGTSLEALCRMKRP Q4T009_TETNG Q4T009_TETNG LEVFVNRMTAPDLNSG---MFKVLLVHVFNCFQVETSTHGNSLNAV-------------- Q207K8_ICTPU Q207K8_ICTPU ------------------------------------------------------------ A5LFW0_MACFA A5LFW0_MACFA LELFVNKTTATKLNSGEDKIEDILVLHLDRGKDYFLSVSGNYLPSCFGSPIHTLCYMREP B3KMW4_HUMAN B3KMW4_HUMAN LELFVNKTTATKLNSGEDKIEDILVLHLDRGKDYFLSVSGNYLPSCFGSPIHTLCYMREP I5P2_HUMAN I5P2_HUMAN LELFVNKTTATKLNSGEDKIEDILVLHLDRGKDYFLSVSGNYLPSCFGSPIHTLCYMREP Q4G006_RAT Q4G006_RAT LELFVNKATATKLNSGKDTIEDILVLHLHRGKDYFLSVTGNYLPSCFGSPIHTLCYMREP Q91ZF8_MOUSE Q91ZF8_MOUSE LELFVNKSTATKLNSGKDTIEDILVLHLERGKDYFLSVSGNYLPSCFGSPIHTLCYMREP Q8CF65_MOUSE Q8CF65_MOUSE LELFVNKSTATKLNSGKDTIEDILVLHLERGKDYFLSVSGNYLPSCFGSPIHTLCYMREP O54996_MOUSE O54996_MOUSE LELFVNKSTATKLNSGKDTIEDILVLHLERGKDYFLSVSGNYLPSCFGSPIHTLCYMREP Q8K337_MOUSE Q8K337_MOUSE LELFVNKSTATKLNSGKDTIEDILVLHLERGKDYFLSVSGNYLPSCFGSPIHTLCYMREP Q9DBW2_MOUSE Q9DBW2_MOUSE LELFVNKSTATKLNSGKDTIEDILVLHLERGKDYFLSVSGNYLPSCFGSPIHTLCYMREP MATCH CONSENSUS L???V?K???T?LNSG?D?IEDILVLHL?RGKDYF????GNYLPSCFG?????LC?M??P

A0JMC7_DANRE A0JMC7_DANRE IREIPITKLIDL--------EKARMTFLLDSAGTE-DKPLKIPKEVWLLVNHLYTKACQQ Q4RTB9_TETNG Q4RTB9_TETNG IREIPITKLIDLGEDSYMDKERSKVNFLTADGTGSEEKPLKIPKEVWILVNHLYTKASDQ Q08BT4_XENTR Q08BT4_XENTR IREIPVTKLIDLGEDSFSEKEKAALQMLPLESDETADKPMKIPKEIWLLVDHLYKNACRQ Q4R433_MACFA Q4R433_MACFA IREVPVTKLIDLEEDSFLEKEKSLLQMVPLDEGAS-ERPLQVPKEIWLLVDHLFKYACHQ Q5R9G5_PONAB Q5R9G5_PONAB IREVPVTKLIDL--------EKSLLQMVPLDEGAS-ERPLQVPKEIWLLVDHLFKYACHQ B7ZLX2_HUMAN B7ZLX2_HUMAN IREVPVTKLIDL--------EKSLLQMVPLDEGAS-ERPLQVPKEIWLLVDHLFKYACHQ A6NNH7_HUMAN A6NNH7_HUMAN IREVPVTKLIDLERTSFNYGEKSLLQMVPLDEGAS-ERPLQVPKEIWLLVDHLFKYACHQ Q504W7_HUMAN Q504W7_HUMAN IREVPVTKLIDL--------EKSLLQMVPLDEGAS-ERPLQVPKEIWLLVDHLFKYACHQ OCRL_HUMAN OCRL_HUMAN IREVPVTKLIDLEEDSFLEKEKSLLQMVPLDEGAS-ERPLQVPKEIWLLVDHLFKYACHQ Q4VY10_HUMAN Q4VY10_HUMAN IREVPVTKLIDLEEDSFLEKEKSLLQMVPLDEGAS-ERPLQVPKEIWLLVDHLFKYACHQ A8KAP2_HUMAN A8KAP2_HUMAN IREVPVTKLIDLEEDSFLEKEKSLLQMVPLDEGAS-ERPLQVPKEIWLLVDHLFKYACHQ A7E337_BOVIN A7E337_BOVIN IREVPVTKLIDL--------EKSLLQMVPLDEGAS-ERPLKVPKEIWLLVDHLFRYACHQ Q8BXT3_MOUSE Q8BXT3_MOUSE ------------------------------------TRP--------------------- Q8BXC9_MOUSE Q8BXC9_MOUSE IREVPVTKLIDL-----------------------------------------------E B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE IREVPVTKLIDLEEDSYLEKEKSLLQMVPLDEGTS-ERPLQVPKEIWLLVDHLFKYACHQ Q80XM6_MOUSE Q80XM6_MOUSE IREVPVTKLIDLEEDSYLEKEKSLLQMVPLDEGTS-ERPLQVPKEIWLLVDHLFKYACHQ Q4T009_TETNG Q4T009_TETNG -------------------------------------KPLDIPKELWMMVDYLFHNAIKQ Q207K8_ICTPU Q207K8_ICTPU ------------------------------------------------------------ A5LFW0_MACFA A5LFW0_MACFA ILDLPLETISEL----------TLMPIRTGDDGSQLESPMEIPKELWMMVDYLYRNAIQQ B3KMW4_HUMAN B3KMW4_HUMAN ILDLPLETISEL----------TLMPVWTGDDGSQLDSPMEIPKELWMMVDYLYRNAVQQ I5P2_HUMAN I5P2_HUMAN ILDLPLETISEL----------TLMPVWTGDDGSQLDSPMEIPKELWMMVDYLYRNAVQQ Q4G006_RAT Q4G006_RAT ILDLPLKIVNEL----------TLMTVQTADDRSQLEKPMEIPKELWMMVDYLYRNAVQQ Q91ZF8_MOUSE Q91ZF8_MOUSE ILDLPLKTVSDL----------T------------------------------------- Q8CF65_MOUSE Q8CF65_MOUSE ILDLPLKTVSDL----------TLMSVQTADDRSQLENPMEIPKELWMMVDYLYRNAVQQ O54996_MOUSE O54996_MOUSE ILDLPLKTVSDL----------TLMSVQTADDRSQLENPMEIPKELWMMVDYLYRNAVQQ Q8K337_MOUSE Q8K337_MOUSE ILDLPLKTVSDL----------TLMSVQTADDRSQLENPMEIPKELWMMVDYLYRNAVQQ Q9DBW2_MOUSE Q9DBW2_MOUSE ILDLPLKTVSDL----------TLMSVQTADDRSQLENPMEIPKELWMMVDYLYRNAVQQ MATCH CONSENSUS I???P??????L??????????????????????????P???PKE?W??V??L???A??Q

A0JMC7_DANRE A0JMC7_DANRE EDLFQTPGLQDELQSIIDCLDTSIPDSIPGCNHSVAEALLIFLEALPEPVLCYELFQRCL Q4RTB9_TETNG Q4RTB9_TETNG EDLFQTPGLQEEMQNIIDSLDTSIPDTISGCNHSVAEVLLIFLEALPEPVVCYELYQRCL Q08BT4_XENTR Q08BT4_XENTR EDLFQTPGKQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCI Q4R433_MACFA Q4R433_MACFA EDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLM------------------- Q5R9G5_PONAB Q5R9G5_PONAB DDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCL B7ZLX2_HUMAN B7ZLX2_HUMAN EDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCL A6NNH7_HUMAN A6NNH7_HUMAN EDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCL Q504W7_HUMAN Q504W7_HUMAN EDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCL OCRL_HUMAN OCRL_HUMAN EDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCL Q4VY10_HUMAN Q4VY10_HUMAN EDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCL A8KAP2_HUMAN A8KAP2_HUMAN EDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCL A7E337_BOVIN A7E337_BOVIN EDLFQTPGMQEELQQIIDCLDTSIPKTI-------------------------------- Q8BXT3_MOUSE Q8BXT3_MOUSE ------------------------------------------------------------ Q8BXC9_MOUSE Q8BXC9_MOUSE EDSY--------LEKVIQSIGGN-------------EGFLVL------------------ B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE EDLFQTPGMQEELQQIIDCLDTSIPETIPGNNHSVAEALLIFLEALPEPVICYELYQRCL Q80XM6_MOUSE Q80XM6_MOUSE EDLFQTPGMQEELQQIIDCLDTSIPETIPGNNHSVAEALLIFLEALPEPVICYELYQRCL Q4T009_TETNG Q4T009_TETNG EDIFQQPGLRSDFAEIRDCLDTGMPDSLPGSNHSVAEGLLLFLDALPEPVVPYSFYQQCL Q207K8_ICTPU Q207K8_ICTPU ------------------------------------------------------------ A5LFW0_MACFA A5LFW0_MACFA EDLFQQPGLRSEFEHVRDCLDTGMIDNLSASNHSVAEALLLFLESLPEPVICYSAYHNCL B3KMW4_HUMAN B3KMW4_HUMAN EDLFQQPGLRSEFEHIRDCLDTGMIDNLSASNHSVAEALLLFLESLPEPVICYSTYHNCL I5P2_HUMAN I5P2_HUMAN EDLFQQPGLRSEFEHIRDCLDTGMIDNLSASNHSVAEALLLFLESLPEPVICYSTYHNCL Q4G006_RAT Q4G006_RAT EDLFQQPGLRPEFEHIRDCLDTGMIDHLCANNHSVAEALLLFLESLPEPVICYSAYHSCL Q91ZF8_MOUSE Q91ZF8_MOUSE ------PG--------------------------------------------------C- Q8CF65_MOUSE Q8CF65_MOUSE EDLFQQPGLRPEFDHIRDCLDTGMIDQLCANNHSVAEALLLFLESLPEPVICYSAYHSCL O54996_MOUSE O54996_MOUSE EDLFQQPGLRPEFDHIRDCLDTGMIDQLCANNHSVAEALLLFLESLPEPVICYSAYHSCL Q8K337_MOUSE Q8K337_MOUSE EDLFQQPGLRPEFDHIRDCLDTGMIDQLCANNHSVAEALLLFLESLPEPVICYSAYHSCL Q9DBW2_MOUSE Q9DBW2_MOUSE EDLFQQPGLRPEFDHIRDCLDTGMIDQLCANNHSVAEALLLFLESLPEPVICYSAYHSCL MATCH CONSENSUS ED?FQ?PG?????????D?LDT??????????????E??L????????????????????

A0JMC7_DANRE A0JMC7_DANRE ECSHDSRLCKQLISQLPRAHRNVFRYLMAFLRELLKHSIDNNLNANLL------------ Q4RTB9_TETNG Q4RTB9_TETNG DCTHDSRLCKQLISQLSSAHRNVFRYLMAFLKELLKHSHNNNLTASLLGMNTQVTMSKSV Q08BT4_XENTR Q08BT4_XENTR DCSHDTRLCRQVISQLPRCHRNVFRYLMAFLRELLKYTGDNNLSANMI------------ Q4R433_MACFA Q4R433_MACFA ------------------------------------------------------------ Q5R9G5_PONAB Q5R9G5_PONAB DSAHDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFSEYNSVNANMI------------ B7ZLX2_HUMAN B7ZLX2_HUMAN DSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFSEYNSVNANMI------------ A6NNH7_HUMAN A6NNH7_HUMAN DSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFSEYNSVNANMI------------ Q504W7_HUMAN Q504W7_HUMAN DSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFSEYNSVNANMI------------ OCRL_HUMAN OCRL_HUMAN DSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFSEYNSVNANMI------------ Q4VY10_HUMAN Q4VY10_HUMAN DSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFSEYNSVNANMI------------ A8KAP2_HUMAN A8KAP2_HUMAN DSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFSEYNSVNANMI------------ A7E337_BOVIN A7E337_BOVIN -----------------------------LTTQWLRHCSFS------------------- Q8BXT3_MOUSE Q8BXT3_MOUSE ------------------------------------------------------------ Q8BXC9_MOUSE Q8BXC9_MOUSE ------------------------------------------------------------ B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------------ Q6NVF0_MOUSE Q6NVF0_MOUSE DSAHDPRICKQVISQLPRCHRNVFRYLMAFLRELLKFSDYNNINTNMI------------ Q80XM6_MOUSE Q80XM6_MOUSE DSAHDPRICKQVISQLPRCHRNVFRYLMAFLRELLKFSDYNNINTNMI------------ Q4T009_TETNG Q4T009_TETNG DCCSNASQCEKVISTLPQYHQNVFNYLTAFLRELLKHTANNRLDVTIL------------ Q207K8_ICTPU Q207K8_ICTPU ------------------------------------------------------------ A5LFW0_MACFA A5LFW0_MACFA ECSGNYTASKQVISTLPTFYKNVFHYLMAFLQELLKNSAKNHLDENIL------------ B3KMW4_HUMAN B3KMW4_HUMAN ECSGNYTASKQVISTLPIFHKNVFHYLMAFLRELLKNSAKNHLHENIL------------ I5P2_HUMAN I5P2_HUMAN ECSGNYTASKQVISTLPIFHKNVFHYLMAFLRELLKNSAKNHLDENIL------------ Q4G006_RAT Q4G006_RAT ECSGSHTASKQVISTLPTFHKNVFSYLMAFLQELLKNSAKNHLDENIL------------ Q91ZF8_MOUSE Q91ZF8_MOUSE QCNGA------------------------------------------------------- Q8CF65_MOUSE Q8CF65_MOUSE ECSGNYAASKQIILTLPSFHKNVFNYLMAFLQELLKNSANNHLDENIL------------ O54996_MOUSE O54996_MOUSE ECSGNYAASKQIILTLPSFHKNVFNYLMAFLQELLKNSANNHLDENIL------------ Q8K337_MOUSE Q8K337_MOUSE ECSGNYAASKQIILTLPSFHKNVFNYLMAFLQELLKNSANNHLDENIL------------ Q9DBW2_MOUSE Q9DBW2_MOUSE ECSGNYAASKQIILTLPSFHKNVFNYLMAFLQELLKNSANNHLDENIL------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A0JMC7_DANRE A0JMC7_DANRE --------------ATLFASLLIRPPPNLAGKQTQHDRQKANDFILGFLMAGDED Q4RTB9_TETNG Q4RTB9_TETNG TTKDPLNTKTRGSCATLFGSLLIRPPPNLAARQTQQDRQKAIDFVLGS------- Q08BT4_XENTR Q08BT4_XENTR --------------ATVFTSLLLRPPPNLIGKQTPSERQRAINFILGFLLSVDEE Q4R433_MACFA Q4R433_MACFA ------------------------------------------------IPGSADR Q5R9G5_PONAB Q5R9G5_PONAB --------------ATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEED B7ZLX2_HUMAN B7ZLX2_HUMAN --------------ATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEED A6NNH7_HUMAN A6NNH7_HUMAN --------------ATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEED Q504W7_HUMAN Q504W7_HUMAN --------------ATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEED OCRL_HUMAN OCRL_HUMAN --------------ATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEED Q4VY10_HUMAN Q4VY10_HUMAN --------------ATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEED A8KAP2_HUMAN A8KAP2_HUMAN --------------ATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEED A7E337_BOVIN A7E337_BOVIN ------------------------------------------------------- Q8BXT3_MOUSE Q8BXT3_MOUSE ------------------------------------------------------- Q8BXC9_MOUSE Q8BXC9_MOUSE ------------------------------------------------------D B1AVT5_MOUSE B1AVT5_MOUSE ------------------------------------------------------- Q6NVF0_MOUSE Q6NVF0_MOUSE --------------ATLFSSLLLRPPPNLMTRQTPNDRQHAIQFLLVFLLGNEED Q80XM6_MOUSE Q80XM6_MOUSE --------------ATLFSSLLLRPPPNLMTRQTPNDRQHAIQFLLVFLLGNEED Q4T009_TETNG Q4T009_TETNG --------------CKSKGTSL--------------------------------- Q207K8_ICTPU Q207K8_ICTPU ------------------------------------------------------- A5LFW0_MACFA A5LFW0_MACFA --------------ASIFGSLLLRNPAGH-QKLDMTEKKKAQEFIHQFLCNPL-- B3KMW4_HUMAN B3KMW4_HUMAN --------------ASIFGSLLLRNPAGH-QKLDMTEKKKAQEFIHQFLCNPL-- I5P2_HUMAN I5P2_HUMAN --------------ASIFGSLLLRNPAGH-QKLDMTEKKKAQEFIHQFLCNPL-- Q4G006_RAT Q4G006_RAT --------------ASIFGSLLLRSPAGH-RKLDMAEKKKAQEFIHHFLCNPL-- Q91ZF8_MOUSE Q91ZF8_MOUSE ------------------AAVLARG------------------------------ Q8CF65_MOUSE Q8CF65_MOUSE --------------ASIFGSLLLRNPARH-QKLDMAEKKKAQEFIHQFLCGPP-- O54996_MOUSE O54996_MOUSE --------------ASIFGSLLLRNPARH-QKLDMAEKKKAQEFIHQFLCGPL-- Q8K337_MOUSE Q8K337_MOUSE --------------ASIFGSLLLRNPARH-QKLDMAEKKKAQEFIHQFLCGPL-- Q9DBW2_MOUSE Q9DBW2_MOUSE --------------ASIFGSLLLRNPARH-QKLDMAEKKKAQEFIHQFLCGPP-- MATCH CONSENSUS ???????????????????????????????????????????????????????


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